USP27X (ubiquitin specific peptidase 27 X-linked) - Rat Genome Database

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Gene: USP27X (ubiquitin specific peptidase 27 X-linked) Sus scrofa
Analyze
Symbol: USP27X
Name: ubiquitin specific peptidase 27 X-linked
RGD ID: 13843174
Description: ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN protein deubiquitination (ortholog); protein K48-linked deubiquitination (ortholog); protein K63-linked deubiquitination (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital disorder of glycosylation type IIm (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 27
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX43,555,005 - 43,556,321 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X43,553,454 - 43,557,247 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X48,462,214 - 48,465,981 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
USP27X
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX43,555,005 - 43,556,321 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X43,553,454 - 43,557,247 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X48,462,214 - 48,465,981 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP27X
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X49,879,484 - 49,882,558 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX49,879,484 - 49,882,558 (+)EnsemblGRCh38hg38GRCh38
GRCh37X49,644,087 - 49,647,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X49,530,949 - 49,533,210 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX53,713,777 - 53,716,476 (+)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX47,113,635 - 47,116,334 (+)NCBIHuRef
CHM1_1X49,724,245 - 49,726,944 (+)NCBICHM1_1
T2T-CHM13v2.0X49,195,374 - 49,198,448 (+)NCBIT2T-CHM13v2.0
Usp27x
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,238,830 - 7,242,069 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,237,513 - 7,242,069 (-)EnsemblGRCm39 Ensembl
GRCm38X7,372,591 - 7,375,830 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX7,371,276 - 7,375,830 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 EnsemblX7,371,274 - 7,375,830 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X6,949,717 - 6,952,956 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X6,528,235 - 6,532,785 (-)NCBIMGSCv36mm8
CeleraX4,096,292 - 4,099,273 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.31NCBI
Usp27x
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,795,506 - 17,798,741 (+)NCBIGRCr8
mRatBN7.2X15,123,620 - 15,126,855 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX15,124,596 - 15,125,912 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX19,937,954 - 19,941,190 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,142,127 - 20,145,363 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X16,407,087 - 16,410,323 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,987,964 - 15,991,149 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,988,604 - 15,990,484 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,772,644 - 16,775,829 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X27,189,208 - 27,199,805 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX15,204,195 - 15,207,324 (+)NCBICelera
Cytogenetic MapXq12NCBI
Usp27x
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555431,023,931 - 1,027,048 (+)NCBIChiLan1.0ChiLan1.0
USP27X
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X51,306,617 - 51,310,196 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X51,309,993 - 51,313,493 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X42,093,799 - 42,097,346 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X49,808,212 - 49,811,792 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX49,809,559 - 49,810,875 (+)Ensemblpanpan1.1panPan2
USP27X
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X42,645,534 - 42,648,801 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX17,022,297 - 17,026,773 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,786,958 - 42,790,207 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X42,769,636 - 42,774,112 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,758,487 - 42,761,735 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,853,307 - 42,856,556 (+)NCBIUU_Cfam_GSD_1.0
Usp27x
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X35,156,310 - 35,159,329 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367211,396,103 - 1,399,745 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367211,396,103 - 1,399,718 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP27X
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X46,718,329 - 46,728,205 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666086309,144 - 313,397 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp27x
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248931,314,670 - 1,329,853 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248931,314,670 - 1,329,823 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in USP27X
24 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1
Low 4 2 2 3 22 2 1
Below cutoff 5 1 1 1 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000013455   ⟹   ENSSSCP00000013095
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX43,555,005 - 43,556,321 (+)Ensembl
RefSeq Acc Id: XM_003135097   ⟹   XP_003135145
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X43,553,454 - 43,557,247 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003135145 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000013095.4
  ENSSSCP00005044204.1
Reference Protein Sequences
RefSeq Acc Id: XP_003135145   ⟸   XM_003135097
- Sequence:
RefSeq Acc Id: ENSSSCP00000013095   ⟸   ENSSSCT00000013455
Protein Domains
USP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012305 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00005044109 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000013455.4 UniProtKB/TrEMBL
  ENSSSCT00005070914.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
NCBI Gene USP27X ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 27 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
PROSITE USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
UniProt A0A4X1VML5_PIG UniProtKB/TrEMBL
UniProt Secondary F1RW22 UniProtKB/TrEMBL