FSIP2-AS2 (FSIP2 antisense RNA 2) - Rat Genome Database

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Gene: FSIP2-AS2 (FSIP2 antisense RNA 2) Homo sapiens
Analyze
Symbol: FSIP2-AS2
Name: FSIP2 antisense RNA 2
RGD ID: 13793157
HGNC Page HGNC:54061
Description:
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382185,719,874 - 185,740,477 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2185,653,303 - 185,802,323 (-)EnsemblGRCh38hg38GRCh38
GRCh372186,584,601 - 186,605,204 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map2q32.1NCBI
HuRef2178,444,688 - 178,460,956 (-)NCBIHuRef
CHM1_12186,590,473 - 186,606,742 (-)NCBICHM1_1
T2T-CHM13v2.02186,208,935 - 186,229,543 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:12477932  


Genomics

Variants

.
Variants in FSIP2-AS2
14 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q31.3-32.1(chr2:180942902-187372388)x1 copy number loss See cases [RCV000137116] Chr2:180942902..187372388 [GRCh38]
Chr2:181807629..188237115 [GRCh37]
Chr2:181515874..187945360 [NCBI36]
Chr2:2q31.3-32.1		 pathogenic
GRCh38/hg38 2q31.1-33.2(chr2:174898848-203941548)x1 copy number loss See cases [RCV000050980] Chr2:174898848..203941548 [GRCh38]
Chr2:175763576..204806271 [GRCh37]
Chr2:175471822..204514516 [NCBI36]
Chr2:2q31.1-33.2		 pathogenic
GRCh38/hg38 2q31.1-33.1(chr2:176304445-202039790)x1 copy number loss See cases [RCV000052558] Chr2:176304445..202039790 [GRCh38]
Chr2:177169173..202904513 [GRCh37]
Chr2:176877419..202612758 [NCBI36]
Chr2:2q31.1-33.1		 pathogenic
GRCh38/hg38 2q31.1-32.2(chr2:171429233-189179568)x1 copy number loss See cases [RCV000136850] Chr2:171429233..189179568 [GRCh38]
Chr2:172285743..190044294 [GRCh37]
Chr2:171993989..189752539 [NCBI36]
Chr2:2q31.1-32.2		 pathogenic
GRCh38/hg38 2q31.2-33.1(chr2:177874070-198525492)x1 copy number loss See cases [RCV000052559] Chr2:177874070..198525492 [GRCh38]
Chr2:178738797..199390216 [GRCh37]
Chr2:178447043..199098461 [NCBI36]
Chr2:2q31.2-33.1		 pathogenic
GRCh38/hg38 2q31.1-32.2(chr2:174634502-189000964)x1 copy number loss See cases [RCV000136861] Chr2:174634502..189000964 [GRCh38]
Chr2:175499230..189865690 [GRCh37]
Chr2:175207476..189573935 [NCBI36]
Chr2:2q31.1-32.2		 pathogenic
GRCh38/hg38 2q31.3-36.2(chr2:180513793-224302848)x3 copy number gain See cases [RCV000139446] Chr2:180513793..224302848 [GRCh38]
Chr2:181378520..225167565 [GRCh37]
Chr2:181086765..224875809 [NCBI36]
Chr2:2q31.3-36.2		 pathogenic
GRCh38/hg38 2q32.1(chr2:185571260-185998642)x1 copy number loss See cases [RCV000141983] Chr2:185571260..185998642 [GRCh38]
Chr2:186435987..186863369 [GRCh37]
Chr2:186144232..186571614 [NCBI36]
Chr2:2q32.1		 uncertain significance|conflicting data from submitters
GRCh38/hg38 2q31.1-32.1(chr2:170407688-186189894)x1 copy number loss See cases [RCV000054127] Chr2:170407688..186189894 [GRCh38]
Chr2:171264198..187054621 [GRCh37]
Chr2:170972444..186762866 [NCBI36]
Chr2:2q31.1-32.1		 pathogenic
GRCh38/hg38 2q31.3-32.3(chr2:181758701-192015392)x1 copy number loss See cases [RCV000138253] Chr2:181758701..192015392 [GRCh38]
Chr2:182623428..192880118 [GRCh37]
Chr2:182331673..192588363 [NCBI36]
Chr2:2q31.3-32.3		 pathogenic
GRCh38/hg38 2q31.2-32.3(chr2:177827730-195125329)x1 copy number loss See cases [RCV000141735] Chr2:177827730..195125329 [GRCh38]
Chr2:178692457..195990053 [GRCh37]
Chr2:178400703..195698298 [NCBI36]
Chr2:2q31.2-32.3		 pathogenic
GRCh38/hg38 2q31.1-32.3(chr2:176086763-193201970)x1 copy number loss See cases [RCV000143484] Chr2:176086763..193201970 [GRCh38]
Chr2:176951491..194066696 [GRCh37]
Chr2:176659737..193774941 [NCBI36]
Chr2:2q31.1-32.3		 pathogenic
NM_173651.4(FSIP2):c.17G>A (p.Gly6Asp) single nucleotide variant not specified [RCV004295656] Chr2:185738911 [GRCh38]
Chr2:186603638 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.4(FSIP2):c.171G>T (p.Leu57=) single nucleotide variant not provided [RCV002512010] Chr2:185739417 [GRCh38]
Chr2:186604144 [GRCh37]
Chr2:2q32.1		 likely benign
NM_173651.2(FSIP2):c.116G>T (p.Gly39Val) single nucleotide variant not specified [RCV004210405] Chr2:185738743 [GRCh38]
Chr2:186603470 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.2(FSIP2):c.65C>A (p.Ala22Glu) single nucleotide variant not specified [RCV004088774] Chr2:185738692 [GRCh38]
Chr2:186603419 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.4(FSIP2):c.-60G>A single nucleotide variant not specified [RCV004141255] Chr2:185738835 [GRCh38]
Chr2:186603562 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.2(FSIP2):c.34C>T (p.Pro12Ser) single nucleotide variant not specified [RCV004216377] Chr2:185738661 [GRCh38]
Chr2:186603388 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.4(FSIP2):c.-38G>A single nucleotide variant not specified [RCV004193004] Chr2:185738857 [GRCh38]
Chr2:186603584 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.4(FSIP2):c.131G>A (p.Gly44Glu) single nucleotide variant not specified [RCV004243663] Chr2:185739377 [GRCh38]
Chr2:186604104 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.2(FSIP2):c.148G>A (p.Gly50Ser) single nucleotide variant not specified [RCV004159362] Chr2:185738775 [GRCh38]
Chr2:186603502 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.4(FSIP2):c.91T>C (p.Cys31Arg) single nucleotide variant not specified [RCV004276614] Chr2:185738985 [GRCh38]
Chr2:186603712 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.4(FSIP2):c.-63A>C single nucleotide variant not specified [RCV004280638] Chr2:185738832 [GRCh38]
Chr2:186603559 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.4(FSIP2):c.-32G>T single nucleotide variant not specified [RCV004284722] Chr2:185738863 [GRCh38]
Chr2:186603590 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.4(FSIP2):c.-44A>G single nucleotide variant not specified [RCV004277928] Chr2:185738851 [GRCh38]
Chr2:186603578 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.4(FSIP2):c.-4G>A single nucleotide variant FSIP2-related condition [RCV003914444] Chr2:185738891 [GRCh38]
Chr2:186603618 [GRCh37]
Chr2:2q32.1		 likely benign
NM_173651.4(FSIP2):c.99C>T (p.Asp33=) single nucleotide variant FSIP2-related condition [RCV003981758] Chr2:185738993 [GRCh38]
Chr2:186603720 [GRCh37]
Chr2:2q32.1		 likely benign
NM_173651.2(FSIP2):c.31A>G (p.Arg11Gly) single nucleotide variant not specified [RCV004387113] Chr2:185738658 [GRCh38]
Chr2:186603385 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.4(FSIP2):c.86A>G (p.Gln29Arg) single nucleotide variant not specified [RCV004387116] Chr2:185738980 [GRCh38]
Chr2:186603707 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.2(FSIP2):c.149G>A (p.Gly50Asp) single nucleotide variant not specified [RCV004387065] Chr2:185738776 [GRCh38]
Chr2:186603503 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.2(FSIP2):c.164T>C (p.Val55Ala) single nucleotide variant not specified [RCV004387075] Chr2:185738791 [GRCh38]
Chr2:186603518 [GRCh37]
Chr2:2q32.1		 likely benign
NM_173651.4(FSIP2):c.-11C>T single nucleotide variant not specified [RCV004387109] Chr2:185738884 [GRCh38]
Chr2:186603611 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_173651.2(FSIP2):c.67C>T (p.Leu23Phe) single nucleotide variant not specified [RCV004387140] Chr2:185738694 [GRCh38]
Chr2:186603421 [GRCh37]
Chr2:2q32.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:104
Interacting mature miRNAs:106
Transcripts:ENST00000421998, ENST00000427269, ENST00000437717
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 6 1 1 1 1 5 123
Low 345 147 938 155 139 76 746 160 1592 120 695 616 80 145 496
Below cutoff 1770 1648 651 354 561 280 2904 1557 2016 220 511 774 80 901 1844 3

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000421998
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2185,719,874 - 185,738,721 (-)Ensembl
RefSeq Acc Id: ENST00000427269
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2185,720,212 - 185,740,479 (-)Ensembl
RefSeq Acc Id: ENST00000437717
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2185,736,062 - 185,739,025 (-)Ensembl
RefSeq Acc Id: NR_110214
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382185,719,874 - 185,739,093 (-)NCBI
T2T-CHM13v2.02186,208,935 - 186,228,159 (-)NCBI
Sequence:
RefSeq Acc Id: NR_110215
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382185,719,874 - 185,738,719 (-)NCBI
T2T-CHM13v2.02186,208,935 - 186,227,784 (-)NCBI
Sequence:
RefSeq Acc Id: NR_110216
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382185,719,874 - 185,738,719 (-)NCBI
T2T-CHM13v2.02186,208,935 - 186,227,784 (-)NCBI
Sequence:
RefSeq Acc Id: NR_110217
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382185,719,874 - 185,740,477 (-)NCBI
T2T-CHM13v2.02186,208,935 - 186,229,543 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC FSIP2-AS2 COSMIC
Ensembl Genes ENSG00000226747 Ensembl
  ENSG00000231646 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000421998 ENTREZGENE
GTEx ENSG00000226747 GTEx
  ENSG00000231646 GTEx
HGNC ID HGNC:54061 ENTREZGENE
Human Proteome Map FSIP2-AS2 Human Proteome Map
NCBI Gene FSIP2-AS2 ENTREZGENE
RNAcentral URS000075A682 RNACentral
  URS000075BFE2 RNACentral
  URS000075C8AF RNACentral
  URS000075CC3B RNACentral