PNLIPRP3 (pancreatic lipase related protein 3) - Rat Genome Database

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Gene: PNLIPRP3 (pancreatic lipase related protein 3) Homo sapiens
Analyze
Symbol: PNLIPRP3
Name: pancreatic lipase related protein 3
RGD ID: 1353570
HGNC Page HGNC:23492
Description: Predicted to enable triglyceride lipase activity. Predicted to be involved in lipid catabolic process. Predicted to be located in extracellular region.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: pancreatic lipase-related protein 3; PL-RP3
RGD Orthologs
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810116,427,847 - 116,477,957 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10116,427,847 - 116,477,957 (+)EnsemblGRCh38hg38GRCh38
GRCh3710118,187,359 - 118,237,469 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610118,177,370 - 118,227,459 (+)NCBINCBI36Build 36hg18NCBI36
Celera10111,916,979 - 111,967,023 (+)NCBICelera
Cytogenetic Map10q25.3NCBI
HuRef10111,814,844 - 111,865,079 (+)NCBIHuRef
CHM1_110118,470,884 - 118,520,910 (+)NCBICHM1_1
T2T-CHM13v2.010117,322,181 - 117,372,229 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19640199   PMID:21873635  


Genomics

Comparative Map Data
PNLIPRP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810116,427,847 - 116,477,957 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10116,427,847 - 116,477,957 (+)EnsemblGRCh38hg38GRCh38
GRCh3710118,187,359 - 118,237,469 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610118,177,370 - 118,227,459 (+)NCBINCBI36Build 36hg18NCBI36
Celera10111,916,979 - 111,967,023 (+)NCBICelera
Cytogenetic Map10q25.3NCBI
HuRef10111,814,844 - 111,865,079 (+)NCBIHuRef
CHM1_110118,470,884 - 118,520,910 (+)NCBICHM1_1
T2T-CHM13v2.010117,322,181 - 117,372,229 (+)NCBIT2T-CHM13v2.0
Or52n20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397104,319,911 - 104,320,879 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7104,315,960 - 104,324,155 (+)EnsemblGRCm39 Ensembl
GRCm387104,670,704 - 104,671,672 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7104,666,753 - 104,674,948 (+)EnsemblGRCm38mm10GRCm38
MGSCv377111,819,218 - 111,820,186 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367104,544,525 - 104,545,493 (+)NCBIMGSCv36mm8
Celera7104,945,193 - 104,946,161 (+)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.69NCBI
PNLIPRP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28128,304,411 - 128,354,455 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110128,309,749 - 128,359,793 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010113,017,080 - 113,067,133 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110116,449,704 - 116,499,681 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10116,457,342 - 116,498,877 (+)Ensemblpanpan1.1panPan2
PNLIPRP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12827,064,823 - 27,092,693 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2827,058,258 - 27,091,134 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2827,215,130 - 27,242,990 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02827,600,908 - 27,628,758 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2827,594,602 - 27,627,472 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12827,155,161 - 27,183,453 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02827,168,806 - 27,203,078 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02827,364,126 - 27,391,978 (+)NCBIUU_Cfam_GSD_1.0
PNLIPRP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14126,677,455 - 126,716,529 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114126,668,569 - 126,717,139 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214137,861,108 - 137,898,039 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PNLIPRP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19109,238,862 - 109,290,181 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9109,238,862 - 109,287,898 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604870,482,663 - 70,532,663 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in PNLIPRP3
14 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q25.3(chr10:114584882-117015907)x1 copy number loss See cases [RCV000050821] Chr10:114584882..117015907 [GRCh38]
Chr10:116344641..118775418 [GRCh37]
Chr10:116334631..118765408 [NCBI36]
Chr10:10q25.3		 pathogenic
GRCh38/hg38 10q23.33-25.3(chr10:95112607-116776637)x3 copy number gain See cases [RCV000050747] Chr10:95112607..116776637 [GRCh38]
Chr10:96872364..118383651 [GRCh37]
Chr10:96862354..118526138 [NCBI36]
Chr10:10q23.33-25.3		 pathogenic
GRCh38/hg38 10q25.2-26.3(chr10:111313099-133620674)x3 copy number gain See cases [RCV000051218] Chr10:111313099..133620674 [GRCh38]
Chr10:113072857..135434178 [GRCh37]
Chr10:113062847..135284168 [NCBI36]
Chr10:10q25.2-26.3		 pathogenic
GRCh38/hg38 10q25.1-26.11(chr10:107191100-118761489)x1 copy number loss See cases [RCV000052570] Chr10:107191100..118761489 [GRCh38]
Chr10:108950858..120521001 [GRCh37]
Chr10:108940848..120510991 [NCBI36]
Chr10:10q25.1-26.11		 pathogenic
GRCh38/hg38 10q23.31-26.3(chr10:91048545-133620674)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|See cases [RCV000053560] Chr10:91048545..133620674 [GRCh38]
Chr10:92808302..135434178 [GRCh37]
Chr10:92798282..135284168 [NCBI36]
Chr10:10q23.31-26.3		 pathogenic
GRCh38/hg38 10q24.31-26.3(chr10:100194215-132432797)x3 copy number gain See cases [RCV000053564] Chr10:100194215..132432797 [GRCh38]
Chr10:101953972..134246301 [GRCh37]
Chr10:101943962..134096291 [NCBI36]
Chr10:10q24.31-26.3		 pathogenic
GRCh38/hg38 10q25.1-26.3(chr10:106925303-133620815)x3 copy number gain See cases [RCV000053588] Chr10:106925303..133620815 [GRCh38]
Chr10:108685061..135434319 [GRCh37]
Chr10:108675051..135284309 [NCBI36]
Chr10:10q25.1-26.3		 pathogenic
GRCh38/hg38 10q25.1-26.3(chr10:108102587-133620674)x3 copy number gain See cases [RCV000133688] Chr10:108102587..133620674 [GRCh38]
Chr10:109862345..135434178 [GRCh37]
Chr10:109852335..135284168 [NCBI36]
Chr10:10q25.1-26.3		 pathogenic
GRCh38/hg38 10q25.2-26.12(chr10:112701186-120970617)x3 copy number gain See cases [RCV000137511] Chr10:112701186..120970617 [GRCh38]
Chr10:114460945..122730130 [GRCh37]
Chr10:114450935..122720120 [NCBI36]
Chr10:10q25.2-26.12		 likely pathogenic
GRCh38/hg38 10q24.31-26.3(chr10:100600492-133622588)x3 copy number gain See cases [RCV000137747] Chr10:100600492..133622588 [GRCh38]
Chr10:102360249..135436092 [GRCh37]
Chr10:102350239..135286082 [NCBI36]
Chr10:10q24.31-26.3		 pathogenic
GRCh38/hg38 10q25.3(chr10:116384965-116504253)x3 copy number gain See cases [RCV000143340] Chr10:116384965..116504253 [GRCh38]
Chr10:118144477..118263765 [GRCh37]
Chr10:118134467..118253755 [NCBI36]
Chr10:10q25.3		 uncertain significance
GRCh37/hg19 10q24.32-26.3(chr10:103288313-135512075)x3 copy number gain See cases [RCV000240457] Chr10:103288313..135512075 [GRCh37]
Chr10:10q24.32-26.3		 pathogenic
GRCh37/hg19 10q24.32-26.3(chr10:104633712-135427143)x3 copy number gain See cases [RCV000449386] Chr10:104633712..135427143 [GRCh37]
Chr10:10q24.32-26.3		 pathogenic
GRCh37/hg19 10q24.2-26.3(chr10:100780957-135427143)x3 copy number gain See cases [RCV000446733] Chr10:100780957..135427143 [GRCh37]
Chr10:10q24.2-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic|uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:106003533-135427143)x3 copy number gain See cases [RCV000510813] Chr10:106003533..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q23.32-26.3(chr10:93283493-135427143)x3 copy number gain See cases [RCV000510972] Chr10:93283493..135427143 [GRCh37]
Chr10:10q23.32-26.3		 pathogenic
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3		 drug response
NM_001011709.3(PNLIPRP3):c.1099G>A (p.Glu367Lys) single nucleotide variant Inborn genetic diseases [RCV003279237] Chr10:116471806 [GRCh38]
Chr10:118231318 [GRCh37]
Chr10:10q25.3		 likely benign
GRCh37/hg19 10q24.33-26.3(chr10:105613040-135427143)x3 copy number gain not provided [RCV000683290] Chr10:105613040..135427143 [GRCh37]
Chr10:10q24.33-26.3		 pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:94346520-135427143)x3 copy number gain not provided [RCV000683291] Chr10:94346520..135427143 [GRCh37]
Chr10:10q23.33-26.3		 pathogenic
GRCh37/hg19 10q25.3(chr10:118102986-118299317)x3 copy number gain not provided [RCV000737300] Chr10:118102986..118299317 [GRCh37]
Chr10:10q25.3		 benign
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q25.1-26.3(chr10:110022170-135439095) copy number gain not provided [RCV000767665] Chr10:110022170..135439095 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q25.3-26.13(chr10:117024753-124942806) copy number loss Distal 10q deletion syndrome [RCV000767564] Chr10:117024753..124942806 [GRCh37]
Chr10:10q25.3-26.13		 pathogenic
GRCh37/hg19 10q25.2-26.3(chr10:114544537-135427143)x3 copy number gain not provided [RCV000847820] Chr10:114544537..135427143 [GRCh37]
Chr10:10q25.2-26.3		 pathogenic
NM_001011709.3(PNLIPRP3):c.1034A>G (p.Asn345Ser) single nucleotide variant Inborn genetic diseases [RCV003240967] Chr10:116469291 [GRCh38]
Chr10:118228803 [GRCh37]
Chr10:10q25.3		 uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:108455687-135427143) copy number gain not specified [RCV002052891] Chr10:108455687..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q25.3-26.13(chr10:117019650-125217066) copy number loss not specified [RCV002052892] Chr10:117019650..125217066 [GRCh37]
Chr10:10q25.3-26.13		 pathogenic
NM_001011709.3(PNLIPRP3):c.400G>C (p.Val134Leu) single nucleotide variant Inborn genetic diseases [RCV002869454] Chr10:116444457 [GRCh38]
Chr10:118203969 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001011709.3(PNLIPRP3):c.583C>A (p.Pro195Thr) single nucleotide variant Inborn genetic diseases [RCV002822067] Chr10:116460983 [GRCh38]
Chr10:118220495 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001011709.3(PNLIPRP3):c.164G>A (p.Arg55His) single nucleotide variant Inborn genetic diseases [RCV003004403] Chr10:116436825 [GRCh38]
Chr10:118196337 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001011709.3(PNLIPRP3):c.1334G>C (p.Gly445Ala) single nucleotide variant Inborn genetic diseases [RCV002807805] Chr10:116476813 [GRCh38]
Chr10:118236325 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001011709.3(PNLIPRP3):c.161C>T (p.Thr54Ile) single nucleotide variant Inborn genetic diseases [RCV002648811] Chr10:116436822 [GRCh38]
Chr10:118196334 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001011709.3(PNLIPRP3):c.269G>A (p.Arg90His) single nucleotide variant Inborn genetic diseases [RCV003296383] Chr10:116443119 [GRCh38]
Chr10:118202631 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001011709.3(PNLIPRP3):c.76G>A (p.Gly26Arg) single nucleotide variant Inborn genetic diseases [RCV003207387] Chr10:116436737 [GRCh38]
Chr10:118196249 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001011709.3(PNLIPRP3):c.695C>T (p.Thr232Ile) single nucleotide variant Inborn genetic diseases [RCV003194311] Chr10:116461177 [GRCh38]
Chr10:118220689 [GRCh37]
Chr10:10q25.3		 uncertain significance
GRCh37/hg19 10p13-q26.3(chr10:12829206-135427143) copy number loss Distal 10q deletion syndrome [RCV003319583] Chr10:12829206..135427143 [GRCh37]
Chr10:10p13-q26.3		 pathogenic
GRCh37/hg19 10p14-q26.3(chr10:11138692-135427143) copy number gain Distal trisomy 10q [RCV003319593] Chr10:11138692..135427143 [GRCh37]
Chr10:10p14-q26.3		 pathogenic
NM_001011709.3(PNLIPRP3):c.245A>G (p.Tyr82Cys) single nucleotide variant not provided [RCV003331464] Chr10:116443095 [GRCh38]
Chr10:118202607 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001011709.3(PNLIPRP3):c.1288A>G (p.Asn430Asp) single nucleotide variant Inborn genetic diseases [RCV003376173] Chr10:116476767 [GRCh38]
Chr10:118236279 [GRCh37]
Chr10:10q25.3		 uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:111378692-135427143)x3 copy number gain Distal trisomy 10q [RCV003458955] Chr10:111378692..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
NM_001011709.3(PNLIPRP3):c.1235A>G (p.Asn412Ser) single nucleotide variant Inborn genetic diseases [RCV003376595] Chr10:116476714 [GRCh38]
Chr10:118236226 [GRCh37]
Chr10:10q25.3		 uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:111447991-133435388)x3 copy number gain not provided [RCV003484817] Chr10:111447991..133435388 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q25.1-26.13(chr10:107129993-123817654)x3 copy number gain not specified [RCV003986891] Chr10:107129993..123817654 [GRCh37]
Chr10:10q25.1-26.13		 likely pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:95078198-135427143)x3 copy number gain not specified [RCV003986893] Chr10:95078198..135427143 [GRCh37]
Chr10:10q23.33-26.3		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:275
Count of miRNA genes:255
Interacting mature miRNAs:263
Transcripts:ENST00000369230
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 3 7 5 1 1168 1 26 1 6 88 583
Low 218 400 62 33 16 2 1016 52 14 22 202 79 35 458 432
Below cutoff 1490 1088 736 171 379 76 1134 1029 1174 71 523 716 97 422 958 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001011709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011539276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011539277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011539278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011539279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054364754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054364755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054364756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054364757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC011328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL833418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC065752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF455287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000369230   ⟹   ENSP00000358232
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10116,427,847 - 116,477,957 (+)Ensembl
RefSeq Acc Id: NM_001011709   ⟹   NP_001011709
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810116,427,847 - 116,477,957 (+)NCBI
GRCh3710118,187,424 - 118,237,469 (+)RGD
Build 3610118,177,370 - 118,227,459 (+)NCBI Archive
Celera10111,916,979 - 111,967,023 (+)RGD
HuRef10111,814,844 - 111,865,079 (+)ENTREZGENE
CHM1_110118,470,884 - 118,520,910 (+)NCBI
T2T-CHM13v2.010117,322,181 - 117,372,229 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011539276   ⟹   XP_011537578
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810116,427,847 - 116,477,957 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011539277   ⟹   XP_011537579
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810116,443,197 - 116,477,957 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011539278   ⟹   XP_011537580
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810116,436,788 - 116,477,957 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011539279   ⟹   XP_011537581
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810116,427,847 - 116,477,957 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054364754   ⟹   XP_054220729
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.010117,322,181 - 117,372,229 (+)NCBI
RefSeq Acc Id: XM_054364755   ⟹   XP_054220730
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.010117,337,533 - 117,372,229 (+)NCBI
RefSeq Acc Id: XM_054364756   ⟹   XP_054220731
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.010117,331,124 - 117,372,229 (+)NCBI
RefSeq Acc Id: XM_054364757   ⟹   XP_054220732
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.010117,322,181 - 117,372,229 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001011709   ⟸   NM_001011709
- Peptide Label: precursor
- UniProtKB: Q17RR3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011537578   ⟸   XM_011539276
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011537581   ⟸   XM_011539279
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011537580   ⟸   XM_011539278
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011537579   ⟸   XM_011539277
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000358232   ⟸   ENST00000369230
RefSeq Acc Id: XP_054220729   ⟸   XM_054364754
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054220732   ⟸   XM_054364757
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054220731   ⟸   XM_054364756
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054220730   ⟸   XM_054364755
- Peptide Label: isoform X2
Protein Domains
PLAT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q17RR3-F1-model_v2 AlphaFold Q17RR3 1-467 view protein structure

Promoters
RGD ID:7218747
Promoter ID:EPDNEW_H15119
Type:initiation region
Name:PNLIPRP3_2
Description:pancreatic lipase related protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15120  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810116,418,672 - 116,418,732EPDNEW
RGD ID:7218749
Promoter ID:EPDNEW_H15120
Type:initiation region
Name:PNLIPRP3_1
Description:pancreatic lipase related protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15119  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810116,427,901 - 116,427,961EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:23492 AgrOrtholog
COSMIC PNLIPRP3 COSMIC
Ensembl Genes ENSG00000203837 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000369230 ENTREZGENE
  ENST00000369230.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot
  PLAT/LH2 domain UniProtKB/Swiss-Prot
GTEx ENSG00000203837 GTEx
HGNC ID HGNC:23492 ENTREZGENE
Human Proteome Map PNLIPRP3 Human Proteome Map
InterPro AB_hydrolase UniProtKB/Swiss-Prot
  Lipase/vitellogenin UniProtKB/Swiss-Prot
  Lipase_LIPH UniProtKB/Swiss-Prot
  Lipase_N UniProtKB/Swiss-Prot
  Lipase_panc UniProtKB/Swiss-Prot
  PLAT/LH2_dom UniProtKB/Swiss-Prot
  PLAT/LH2_dom_sf UniProtKB/Swiss-Prot
  TAG_lipase UniProtKB/Swiss-Prot
KEGG Report hsa:119548 UniProtKB/Swiss-Prot
NCBI Gene 119548 ENTREZGENE
PANTHER PANCREATIC LIPASE-RELATED PROTEIN 3 UniProtKB/Swiss-Prot
  PTHR11610 UniProtKB/Swiss-Prot
Pfam Lipase UniProtKB/Swiss-Prot
  PLAT UniProtKB/Swiss-Prot
PharmGKB PA134954941 PharmGKB
PIRSF Lipoprotein_lipase_LIPH UniProtKB/Swiss-Prot
PRINTS PANCLIPASE UniProtKB/Swiss-Prot
  TAGLIPASE UniProtKB/Swiss-Prot
PROSITE LIPASE_SER UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49723 UniProtKB/Swiss-Prot
  SSF53474 UniProtKB/Swiss-Prot
UniProt LIPR3_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-16 PNLIPRP3  pancreatic lipase related protein 3    pancreatic lipase-related protein 3  Symbol and/or name change 5135510 APPROVED