TEX36 (testis expressed 36) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: TEX36 (testis expressed 36) Homo sapiens
Analyze
Symbol: TEX36
Name: testis expressed 36
RGD ID: 1352588
HGNC Page HGNC:31653
Description: INTERACTS WITH benzo[a]pyrene; lead(0); 17beta-estradiol (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bA383C5.1; C10orf122; FLJ27500; MGC157877; MGC157878; putative uncharacterized protein C10orf122; testis-expressed protein 36; testis-expressed sequence 36 protein
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810125,576,522 - 125,683,163 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10125,576,522 - 125,683,163 (-)EnsemblGRCh38hg38GRCh38
GRCh3710127,265,091 - 127,371,732 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610127,344,263 - 127,371,713 (-)NCBINCBI36Build 36hg18NCBI36
Celera10121,119,677 - 121,147,126 (-)NCBICelera
Cytogenetic Map10q26.13NCBI
HuRef10121,033,659 - 121,061,108 (-)NCBIHuRef
CHM1_110127,625,990 - 127,653,441 (-)NCBICHM1_1
T2T-CHM13v2.010126,458,967 - 126,565,578 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15164054   PMID:15489334   PMID:20379614   PMID:20708005   PMID:21382349   PMID:25609649   PMID:33961781  


Genomics

Comparative Map Data
TEX36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810125,576,522 - 125,683,163 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10125,576,522 - 125,683,163 (-)EnsemblGRCh38hg38GRCh38
GRCh3710127,265,091 - 127,371,732 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610127,344,263 - 127,371,713 (-)NCBINCBI36Build 36hg18NCBI36
Celera10121,119,677 - 121,147,126 (-)NCBICelera
Cytogenetic Map10q26.13NCBI
HuRef10121,033,659 - 121,061,108 (-)NCBIHuRef
CHM1_110127,625,990 - 127,653,441 (-)NCBICHM1_1
T2T-CHM13v2.010126,458,967 - 126,565,578 (-)NCBIT2T-CHM13v2.0
Tex36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397133,188,753 - 133,203,844 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7133,188,753 - 133,203,887 (-)EnsemblGRCm39 Ensembl
GRCm387133,587,024 - 133,602,115 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7133,587,024 - 133,602,158 (-)EnsemblGRCm38mm10GRCm38
MGSCv377140,778,707 - 140,793,798 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367133,425,367 - 133,440,501 (-)NCBIMGSCv36mm8
Celera7133,391,860 - 133,407,043 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map777.09NCBI
Tex36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,820,066 - 197,834,473 (-)NCBIGRCr8
mRatBN7.21188,390,062 - 188,404,448 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1188,390,064 - 188,404,377 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1196,740,106 - 196,754,466 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01203,916,729 - 203,931,085 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01196,590,250 - 196,604,611 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01205,615,759 - 205,630,073 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1205,615,761 - 205,669,760 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01212,603,754 - 212,618,068 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41193,083,749 - 193,098,063 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1186,129,994 - 186,144,218 (-)NCBICelera
Cytogenetic Map1q41NCBI
Tex36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554773,562,442 - 3,576,730 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554773,562,667 - 3,579,915 (-)NCBIChiLan1.0ChiLan1.0
TEX36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28137,426,421 - 137,533,710 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110137,431,772 - 137,539,061 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010122,137,207 - 122,244,324 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110126,401,351 - 126,508,429 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10126,401,533 - 126,508,429 (-)Ensemblpanpan1.1panPan2
TEX36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12834,834,489 - 34,856,911 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2834,835,397 - 34,856,793 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2834,893,558 - 34,915,992 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02835,392,614 - 35,415,052 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2835,403,986 - 35,414,919 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12834,946,399 - 34,968,832 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02834,938,028 - 34,960,451 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02835,197,891 - 35,220,328 (-)NCBIUU_Cfam_GSD_1.0
Tex36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721311,858,589 - 11,870,927 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648613,690,496 - 13,702,577 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648613,690,679 - 13,702,577 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TEX36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14134,994,034 - 135,009,308 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114134,993,483 - 135,001,781 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214146,602,143 - 146,617,494 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TEX36
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19118,275,546 - 118,310,201 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9118,285,362 - 118,310,043 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604879,577,489 - 79,667,443 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tex36
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473721,476,737 - 21,493,948 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473721,476,588 - 21,500,320 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TEX36
10 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q25.2-26.3(chr10:111313099-133620674)x3 copy number gain See cases [RCV000051218] Chr10:111313099..133620674 [GRCh38]
Chr10:113072857..135434178 [GRCh37]
Chr10:113062847..135284168 [NCBI36]
Chr10:10q25.2-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:122265252-133620674)x1 copy number loss See cases [RCV000051069] Chr10:122265252..133620674 [GRCh38]
Chr10:124024767..135434178 [GRCh37]
Chr10:124014757..135284168 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.12-26.3(chr10:120454430-133620674)x1 copy number loss See cases [RCV000051103] Chr10:120454430..133620674 [GRCh38]
Chr10:122213942..135434178 [GRCh37]
Chr10:122203932..135284168 [NCBI36]
Chr10:10q26.12-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:123307835-133620674)x1 copy number loss See cases [RCV000051150] Chr10:123307835..133620674 [GRCh38]
Chr10:125067351..135434178 [GRCh37]
Chr10:125057341..135284168 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.2(chr10:122826743-126730948)x1 copy number loss See cases [RCV000052609] Chr10:122826743..126730948 [GRCh38]
Chr10:124586259..128419517 [GRCh37]
Chr10:124576249..128409507 [NCBI36]
Chr10:10q26.13-26.2		 pathogenic
GRCh38/hg38 10q26.13-26.2(chr10:122973296-128210291)x1 copy number loss See cases [RCV000052610] Chr10:122973296..128210291 [GRCh38]
Chr10:124732812..130008555 [GRCh37]
Chr10:124722802..129898545 [NCBI36]
Chr10:10q26.13-26.2		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:123580320-133558988)x1 copy number loss See cases [RCV000052611] Chr10:123580320..133558988 [GRCh38]
Chr10:125339836..135372492 [GRCh37]
Chr10:125329826..135222482 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q23.31-26.3(chr10:91048545-133620674)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|See cases [RCV000053560] Chr10:91048545..133620674 [GRCh38]
Chr10:92808302..135434178 [GRCh37]
Chr10:92798282..135284168 [NCBI36]
Chr10:10q23.31-26.3		 pathogenic
GRCh38/hg38 10q24.31-26.3(chr10:100194215-132432797)x3 copy number gain See cases [RCV000053564] Chr10:100194215..132432797 [GRCh38]
Chr10:101953972..134246301 [GRCh37]
Chr10:101943962..134096291 [NCBI36]
Chr10:10q24.31-26.3		 pathogenic
GRCh38/hg38 10q25.1-26.3(chr10:106925303-133620815)x3 copy number gain See cases [RCV000053588] Chr10:106925303..133620815 [GRCh38]
Chr10:108685061..135434319 [GRCh37]
Chr10:108675051..135284309 [NCBI36]
Chr10:10q25.1-26.3		 pathogenic
GRCh38/hg38 10q26.11-26.3(chr10:117866565-133554210)x3 copy number gain See cases [RCV000053589] Chr10:117866565..133554210 [GRCh38]
Chr10:119626076..135367714 [GRCh37]
Chr10:119616066..135217704 [NCBI36]
Chr10:10q26.11-26.3		 pathogenic
NM_001128202.1(TEX36):c.25C>T (p.Pro9Ser) single nucleotide variant Malignant melanoma [RCV000068848] Chr10:125682965 [GRCh38]
Chr10:127371534 [GRCh37]
Chr10:127361524 [NCBI36]
Chr10:10q26.13		 not provided
GRCh37/hg19 10q25.2-26.3(chr10:114544537-135427143)x3 copy number gain not provided [RCV000847820] Chr10:114544537..135427143 [GRCh37]
Chr10:10q25.2-26.3		 pathogenic
GRCh38/hg38 10q25.1-26.3(chr10:108102587-133620674)x3 copy number gain See cases [RCV000133688] Chr10:108102587..133620674 [GRCh38]
Chr10:109862345..135434178 [GRCh37]
Chr10:109852335..135284168 [NCBI36]
Chr10:10q25.1-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:125657472-133620674)x1 copy number loss See cases [RCV000133741] Chr10:125657472..133620674 [GRCh38]
Chr10:127346041..135434178 [GRCh37]
Chr10:127336031..135284168 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:124473108-133620609)x1 copy number loss See cases [RCV000136028] Chr10:124473108..133620609 [GRCh38]
Chr10:126161677..135434113 [GRCh37]
Chr10:126151667..135284103 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.2(chr10:124032888-127368827)x3 copy number gain See cases [RCV000136887] Chr10:124032888..127368827 [GRCh38]
Chr10:125792404..129167091 [GRCh37]
Chr10:125782394..129057081 [NCBI36]
Chr10:10q26.13-26.2		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:124834858-133622588)x1 copy number loss See cases [RCV000137653] Chr10:124834858..133622588 [GRCh38]
Chr10:126523427..135436092 [GRCh37]
Chr10:126513417..135286082 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.2(chr10:124912981-125968614)x1 copy number loss See cases [RCV000138151] Chr10:124912981..125968614 [GRCh38]
Chr10:126601550..127657183 [GRCh37]
Chr10:126591540..127647173 [NCBI36]
Chr10:10q26.13-26.2		 pathogenic
GRCh38/hg38 10q24.31-26.3(chr10:100600492-133622588)x3 copy number gain See cases [RCV000137747] Chr10:100600492..133622588 [GRCh38]
Chr10:102360249..135436092 [GRCh37]
Chr10:102350239..135286082 [NCBI36]
Chr10:10q24.31-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:122881207-133620609)x1 copy number loss See cases [RCV000138435] Chr10:122881207..133620609 [GRCh38]
Chr10:124640723..135434113 [GRCh37]
Chr10:124630713..135284103 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.12-26.3(chr10:120970558-133622588)x1 copy number loss See cases [RCV000139344] Chr10:120970558..133622588 [GRCh38]
Chr10:122730071..135436092 [GRCh37]
Chr10:122720061..135286082 [NCBI36]
Chr10:10q26.12-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:125316124-130269667)x1 copy number loss See cases [RCV000139127] Chr10:125316124..130269667 [GRCh38]
Chr10:127004693..132067931 [GRCh37]
Chr10:126994683..131957921 [NCBI36]
Chr10:10q26.13-26.3		 likely benign
GRCh38/hg38 10q26.13-26.3(chr10:125021995-133620609)x1 copy number loss See cases [RCV000139588] Chr10:125021995..133620609 [GRCh38]
Chr10:126710564..135434113 [GRCh37]
Chr10:126700554..135284103 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:125452905-133785874)x3 copy number gain See cases [RCV000141337] Chr10:125452905..133785874 [GRCh38]
Chr10:127141474..135523199 [GRCh37]
Chr10:127131464..135373189 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.11-26.3(chr10:119707856-133613639)x3 copy number gain See cases [RCV000142005] Chr10:119707856..133613639 [GRCh38]
Chr10:121467368..135427143 [GRCh37]
Chr10:121457358..135277133 [NCBI36]
Chr10:10q26.11-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:121588992-133620674)x1 copy number loss See cases [RCV000142441] Chr10:121588992..133620674 [GRCh38]
Chr10:123348506..135434178 [GRCh37]
Chr10:123338496..135284168 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:121918547-133620674)x1 copy number loss See cases [RCV000142737] Chr10:121918547..133620674 [GRCh38]
Chr10:123678062..135434178 [GRCh37]
Chr10:123668052..135284168 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:123986772-133613639)x1 copy number loss See cases [RCV000143623] Chr10:123986772..133613639 [GRCh38]
Chr10:125746288..135427143 [GRCh37]
Chr10:125736278..135277133 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:123576393-133613639)x1 copy number loss See cases [RCV000143544] Chr10:123576393..133613639 [GRCh38]
Chr10:125335909..135427143 [GRCh37]
Chr10:125325899..135277133 [NCBI36]
Chr10:10q26.13-26.3		 pathogenic
GRCh37/hg19 10q26.12-26.2(chr10:122239239-128203032)x1 copy number loss See cases [RCV000240153] Chr10:122239239..128203032 [GRCh37]
Chr10:10q26.12-26.2		 pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:123731209-135353867)x1 copy number loss See cases [RCV000203440] Chr10:123731209..135353867 [GRCh37]
Chr10:10q26.13-26.3		 pathogenic|likely pathogenic
GRCh37/hg19 10q24.32-26.3(chr10:103288313-135512075)x3 copy number gain See cases [RCV000240457] Chr10:103288313..135512075 [GRCh37]
Chr10:10q24.32-26.3		 pathogenic
GRCh37/hg19 10p13-q26.3(chr10:12829206-135427143) copy number loss Distal 10q deletion syndrome [RCV003319583] Chr10:12829206..135427143 [GRCh37]
Chr10:10p13-q26.3		 pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122125760-135062972)x3 copy number gain See cases [RCV000449169] Chr10:122125760..135062972 [GRCh37]
Chr10:10q26.12-26.3		 likely pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:124147428-135370736)x1 copy number loss See cases [RCV000449336] Chr10:124147428..135370736 [GRCh37]
Chr10:10q26.13-26.3		 pathogenic
GRCh37/hg19 10q24.32-26.3(chr10:104633712-135427143)x3 copy number gain See cases [RCV000449386] Chr10:104633712..135427143 [GRCh37]
Chr10:10q24.32-26.3		 pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122343861-135427143)x1 copy number loss See cases [RCV000446095] Chr10:122343861..135427143 [GRCh37]
Chr10:10q26.12-26.3		 pathogenic
GRCh37/hg19 10q24.2-26.3(chr10:100780957-135427143)x3 copy number gain See cases [RCV000446733] Chr10:100780957..135427143 [GRCh37]
Chr10:10q24.2-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic|uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:106003533-135427143)x3 copy number gain See cases [RCV000510813] Chr10:106003533..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q23.32-26.3(chr10:93283493-135427143)x3 copy number gain See cases [RCV000510972] Chr10:93283493..135427143 [GRCh37]
Chr10:10q23.32-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3		 drug response
GRCh37/hg19 10q26.13-26.2(chr10:126652011-128433378)x3 copy number gain not provided [RCV000683267] Chr10:126652011..128433378 [GRCh37]
Chr10:10q26.13-26.2		 uncertain significance
GRCh37/hg19 10q26.13-26.3(chr10:125450893-135427143)x1 copy number loss not provided [RCV000683285] Chr10:125450893..135427143 [GRCh37]
Chr10:10q26.13-26.3		 pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:123019239-135427143)x1 copy number loss not provided [RCV000683286] Chr10:123019239..135427143 [GRCh37]
Chr10:10q26.12-26.3		 pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122509781-135427143)x1 copy number loss not provided [RCV000683287] Chr10:122509781..135427143 [GRCh37]
Chr10:10q26.12-26.3		 pathogenic
GRCh37/hg19 10q24.33-26.3(chr10:105613040-135427143)x3 copy number gain not provided [RCV000683290] Chr10:105613040..135427143 [GRCh37]
Chr10:10q24.33-26.3		 pathogenic
GRCh37/hg19 10q26.11-26.3(chr10:121269222-135427143)x3 copy number gain not provided [RCV000683288] Chr10:121269222..135427143 [GRCh37]
Chr10:10q26.11-26.3		 pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:94346520-135427143)x3 copy number gain not provided [RCV000683291] Chr10:94346520..135427143 [GRCh37]
Chr10:10q23.33-26.3		 pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122443197-135477883)x1 copy number loss not provided [RCV000737305] Chr10:122443197..135477883 [GRCh37]
Chr10:10q26.12-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q25.1-26.3(chr10:110022170-135439095) copy number gain not provided [RCV000767665] Chr10:110022170..135439095 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:124988334-135427143)x3 copy number gain not provided [RCV000848791] Chr10:124988334..135427143 [GRCh37]
Chr10:10q26.13-26.3		 pathogenic
GRCh37/hg19 10q26.11-26.3(chr10:119996339-135427143)x3 copy number gain not provided [RCV001006356] Chr10:119996339..135427143 [GRCh37]
Chr10:10q26.11-26.3		 pathogenic
GRCh37/hg19 10q25.3-26.3(chr10:118247181-135435319)x3 copy number gain not provided [RCV001537903] Chr10:118247181..135435319 [GRCh37]
Chr10:10q25.3-26.3		 pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122785023-135457222)x1 copy number loss See cases [RCV001526488] Chr10:122785023..135457222 [GRCh37]
Chr10:10q26.12-26.3		 pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122125760-135062972) copy number gain not specified [RCV002052894] Chr10:122125760..135062972 [GRCh37]
Chr10:10q26.12-26.3		 likely pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122343861-135427143) copy number loss not specified [RCV002052895] Chr10:122343861..135427143 [GRCh37]
Chr10:10q26.12-26.3		 pathogenic
GRCh37/hg19 10q25.1-26.3(chr10:108455687-135427143) copy number gain not specified [RCV002052891] Chr10:108455687..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q26.13-26.2(chr10:127128172-127999424)x3 copy number gain not provided [RCV001827939] Chr10:127128172..127999424 [GRCh37]
Chr10:10q26.13-26.2		 uncertain significance
GRCh37/hg19 10q26.13-26.3(chr10:126914469-135427143)x1 copy number loss See cases [RCV002292397] Chr10:126914469..135427143 [GRCh37]
Chr10:10q26.13-26.3		 pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:127198625-135427143)x3 copy number gain See cases [RCV002292400] Chr10:127198625..135427143 [GRCh37]
Chr10:10q26.13-26.3		 pathogenic
Single allele duplication not specified [RCV002286381] Chr10:124920875..125841697 [GRCh38]
Chr10:10q26.13-26.2		 uncertain significance
GRCh37/hg19 10q26.13-26.3(chr10:126662496-133985966)x3 copy number gain not provided [RCV002474692] Chr10:126662496..133985966 [GRCh37]
Chr10:10q26.13-26.3		 uncertain significance
NM_001128202.3(TEX36):c.25C>A (p.Pro9Thr) single nucleotide variant not specified [RCV004194987] Chr10:125682965 [GRCh38]
Chr10:127371534 [GRCh37]
Chr10:10q26.13		 uncertain significance
NM_001128202.3(TEX36):c.106T>C (p.Ser36Pro) single nucleotide variant not specified [RCV004151591] Chr10:125661923 [GRCh38]
Chr10:127350492 [GRCh37]
Chr10:10q26.13		 uncertain significance
NM_001128202.3(TEX36):c.176G>A (p.Arg59Gln) single nucleotide variant not specified [RCV004137003] Chr10:125661853 [GRCh38]
Chr10:127350422 [GRCh37]
Chr10:10q26.13		 uncertain significance
NM_001128202.3(TEX36):c.554A>T (p.Glu185Val) single nucleotide variant not specified [RCV004165995] Chr10:125655907 [GRCh38]
Chr10:127344476 [GRCh37]
Chr10:10q26.13		 uncertain significance
NM_001128202.3(TEX36):c.116C>T (p.Pro39Leu) single nucleotide variant not specified [RCV004073848] Chr10:125661913 [GRCh38]
Chr10:127350482 [GRCh37]
Chr10:10q26.13		 uncertain significance
NM_001128202.3(TEX36):c.274C>T (p.Arg92Cys) single nucleotide variant not specified [RCV004078833] Chr10:125656187 [GRCh38]
Chr10:127344756 [GRCh37]
Chr10:10q26.13		 uncertain significance
GRCh37/hg19 10q26.12-26.3(chr10:122610933-135439810)x1 copy number loss not provided [RCV003222684] Chr10:122610933..135439810 [GRCh37]
Chr10:10q26.12-26.3		 pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:123477898-135427143) copy number loss Distal 10q deletion syndrome [RCV003319590] Chr10:123477898..135427143 [GRCh37]
Chr10:10q26.13-26.3		 pathogenic
GRCh37/hg19 10p14-q26.3(chr10:11138692-135427143) copy number gain Distal trisomy 10q [RCV003319593] Chr10:11138692..135427143 [GRCh37]
Chr10:10p14-q26.3		 pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:124895517-135440296)x1 copy number loss Distal 10q deletion syndrome [RCV003329543] Chr10:124895517..135440296 [GRCh37]
Chr10:10q26.13-26.3		 pathogenic
NM_001128202.3(TEX36):c.433C>G (p.Arg145Gly) single nucleotide variant not specified [RCV004363130] Chr10:125656028 [GRCh38]
Chr10:127344597 [GRCh37]
Chr10:10q26.13		 uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:111378692-135427143)x3 copy number gain Distal trisomy 10q [RCV003458955] Chr10:111378692..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
NM_001128202.3(TEX36):c.314G>T (p.Arg105Ile) single nucleotide variant not specified [RCV004365742] Chr10:125656147 [GRCh38]
Chr10:127344716 [GRCh37]
Chr10:10q26.13		 uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:111447991-133435388)x3 copy number gain not provided [RCV003484817] Chr10:111447991..133435388 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:125987494-135427143)x1 copy number loss not specified [RCV003986904] Chr10:125987494..135427143 [GRCh37]
Chr10:10q26.13-26.3		 pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:126127397-135427143)x1 copy number loss not specified [RCV003986878] Chr10:126127397..135427143 [GRCh37]
Chr10:10q26.13-26.3		 pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:95078198-135427143)x3 copy number gain not specified [RCV003986893] Chr10:95078198..135427143 [GRCh37]
Chr10:10q23.33-26.3		 pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122331280-135426386)x1 copy number loss not provided [RCV004442821] Chr10:122331280..135426386 [GRCh37]
Chr10:10q26.12-26.3		 pathogenic
NM_001128202.3(TEX36):c.62T>A (p.Ile21Asn) single nucleotide variant not specified [RCV004472281] Chr10:125661967 [GRCh38]
Chr10:127350536 [GRCh37]
Chr10:10q26.13		 uncertain significance
NM_001128202.3(TEX36):c.304C>T (p.His102Tyr) single nucleotide variant not specified [RCV004472280] Chr10:125656157 [GRCh38]
Chr10:127344726 [GRCh37]
Chr10:10q26.13		 uncertain significance
NM_001128202.3(TEX36):c.181A>G (p.Lys61Glu) single nucleotide variant not specified [RCV004472279] Chr10:125661848 [GRCh38]
Chr10:127350417 [GRCh37]
Chr10:10q26.13		 uncertain significance
NM_001128202.3(TEX36):c.91A>G (p.Ile31Val) single nucleotide variant not specified [RCV004472282] Chr10:125661938 [GRCh38]
Chr10:127350507 [GRCh37]
Chr10:10q26.13		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:369
Count of miRNA genes:292
Interacting mature miRNAs:307
Transcripts:ENST00000368821, ENST00000526819, ENST00000532135
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D10S1286E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371630,081,503 - 30,081,670UniSTSGRCh37
GRCh3710127,355,309 - 127,355,474UniSTSGRCh37
Build 3610127,345,299 - 127,345,464RGDNCBI36
Celera1672,714,050 - 72,714,217UniSTS
Celera10121,130,723 - 121,130,888RGD
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map10q26.13UniSTS
HuRef1627,742,771 - 27,742,938UniSTS
HuRef10121,044,705 - 121,044,870UniSTS
ALDOA  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710127,355,450 - 127,355,676UniSTSGRCh37
Celera10121,130,864 - 121,131,090UniSTS
HuRef352,290,743 - 52,290,990UniSTS
HuRef10121,044,846 - 121,045,072UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium 1 315 1
Low 9 6 1 3 2 12 12 14 1 125 36 2 2
Below cutoff 231 165 174 50 120 19 433 128 631 18 291 286 35 232 217

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000368821   ⟹   ENSP00000357811
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10125,655,694 - 125,683,163 (-)Ensembl
RefSeq Acc Id: ENST00000526819   ⟹   ENSP00000434299
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10125,621,613 - 125,683,130 (-)Ensembl
RefSeq Acc Id: ENST00000532135   ⟹   ENSP00000431764
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10125,576,522 - 125,683,106 (-)Ensembl
RefSeq Acc Id: NM_001128202   ⟹   NP_001121674
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810125,655,694 - 125,683,163 (-)NCBI
GRCh3710127,265,091 - 127,371,735 (-)NCBI
Celera10121,119,677 - 121,147,126 (-)RGD
HuRef10121,033,659 - 121,061,108 (-)RGD
CHM1_110127,625,990 - 127,653,441 (-)NCBI
T2T-CHM13v2.010126,538,108 - 126,565,578 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001318133   ⟹   NP_001305062
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810125,576,522 - 125,683,163 (-)NCBI
CHM1_110127,546,826 - 127,653,441 (-)NCBI
T2T-CHM13v2.010126,458,967 - 126,565,578 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005269817   ⟹   XP_005269874
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810125,639,244 - 125,683,163 (-)NCBI
GRCh3710127,265,091 - 127,371,735 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054365903   ⟹   XP_054221878
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.010126,521,658 - 126,565,578 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001121674   ⟸   NM_001128202
- Peptide Label: isoform a
- UniProtKB: Q0P5T8 (UniProtKB/Swiss-Prot),   Q5VZQ5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005269874   ⟸   XM_005269817
- Peptide Label: isoform X1
- UniProtKB: E9PR91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001305062   ⟸   NM_001318133
- Peptide Label: isoform b
- UniProtKB: A0PJZ8 (UniProtKB/TrEMBL),   E9PJL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000431764   ⟸   ENST00000532135
RefSeq Acc Id: ENSP00000357811   ⟸   ENST00000368821
RefSeq Acc Id: ENSP00000434299   ⟸   ENST00000526819
RefSeq Acc Id: XP_054221878   ⟸   XM_054365903
- Peptide Label: isoform X1
Protein Domains
Domain of unknown function with conserved HDNR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5VZQ5-F1-model_v2 AlphaFold Q5VZQ5 1-186 view protein structure

Promoters
RGD ID:7218963
Promoter ID:EPDNEW_H15227
Type:initiation region
Name:TEX36_1
Description:testis expressed 36
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810125,683,127 - 125,683,187EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31653 AgrOrtholog
COSMIC TEX36 COSMIC
Ensembl Genes ENSG00000175018 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000368821 ENTREZGENE
  ENST00000368821.4 UniProtKB/Swiss-Prot
  ENST00000526819.5 UniProtKB/TrEMBL
  ENST00000532135 ENTREZGENE
  ENST00000532135.5 UniProtKB/TrEMBL
GTEx ENSG00000175018 GTEx
HGNC ID HGNC:31653 ENTREZGENE
Human Proteome Map TEX36 Human Proteome Map
InterPro HDNR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:387718 UniProtKB/Swiss-Prot
NCBI Gene 387718 ENTREZGENE
PANTHER TESTIS-EXPRESSED PROTEIN 36 UniProtKB/Swiss-Prot
  TESTIS-EXPRESSED PROTEIN 36 UniProtKB/Swiss-Prot
  TESTIS-EXPRESSED PROTEIN 36 UniProtKB/TrEMBL
  TESTIS-EXPRESSED PROTEIN 36 UniProtKB/TrEMBL
Pfam HDNR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134969142 PharmGKB
UniProt A0PJZ8 ENTREZGENE, UniProtKB/TrEMBL
  E9PJL2 ENTREZGENE, UniProtKB/TrEMBL
  E9PR91 ENTREZGENE, UniProtKB/TrEMBL
  Q0P5T8 ENTREZGENE
  Q5VZQ5 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q0P5T8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-21 TEX36  testis expressed 36  C10orf122  chromosome 10 open reading frame 122  Symbol and/or name change 5135510 APPROVED