ZBTB22 (zinc finger and BTB domain containing 22) - Rat Genome Database

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Gene: ZBTB22 (zinc finger and BTB domain containing 22) Homo sapiens
Analyze
Symbol: ZBTB22
Name: zinc finger and BTB domain containing 22
RGD ID: 1352119
HGNC Page HGNC:13085
Description: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BING1; fru; fruitless; ZBTB22A; zinc finger and BTB domain-containing protein 22; zinc finger and BTB domain-containing protein 22A; zinc finger protein 297; ZNF297; ZNF297A
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38633,314,418 - 33,317,942 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl633,314,406 - 33,317,942 (-)EnsemblGRCh38hg38GRCh38
GRCh37633,282,195 - 33,285,719 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,390,173 - 33,393,472 (-)NCBINCBI36Build 36hg18NCBI36
Build 34633,390,173 - 33,393,472NCBI
Celera634,836,547 - 34,840,085 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef633,023,752 - 33,027,291 (-)NCBIHuRef
CHM1_1633,284,116 - 33,287,635 (-)NCBICHM1_1
T2T-CHM13v2.0633,135,780 - 33,139,304 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatin  (ISA)
nucleus  (IEA,TAS)

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9521053   PMID:9545376   PMID:12477932   PMID:14574404   PMID:14702039   PMID:15489334   PMID:16169070   PMID:16189514   PMID:16344560   PMID:19851445   PMID:20211142   PMID:21873635  
PMID:21988832   PMID:25416956   PMID:27107014   PMID:28065597   PMID:28473536   PMID:32296183  


Genomics

Comparative Map Data
ZBTB22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38633,314,418 - 33,317,942 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl633,314,406 - 33,317,942 (-)EnsemblGRCh38hg38GRCh38
GRCh37633,282,195 - 33,285,719 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,390,173 - 33,393,472 (-)NCBINCBI36Build 36hg18NCBI36
Build 34633,390,173 - 33,393,472NCBI
Celera634,836,547 - 34,840,085 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef633,023,752 - 33,027,291 (-)NCBIHuRef
CHM1_1633,284,116 - 33,287,635 (-)NCBICHM1_1
T2T-CHM13v2.0633,135,780 - 33,139,304 (-)NCBIT2T-CHM13v2.0
Zbtb22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,135,150 - 34,138,299 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,134,878 - 34,138,299 (+)EnsemblGRCm39 Ensembl
GRCm381733,916,176 - 33,919,325 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1733,915,904 - 33,919,325 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,053,121 - 34,056,270 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,526,683 - 33,529,779 (+)NCBIMGSCv36mm8
Celera1736,669,100 - 36,672,249 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Zbtb22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,968,215 - 4,971,734 (-)NCBIGRCr8
mRatBN7.2204,966,331 - 4,969,853 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,966,271 - 4,969,498 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,689,736 - 5,692,902 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0205,051,481 - 5,054,647 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,532,230 - 5,535,393 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,476,345 - 5,479,900 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,476,345 - 5,479,511 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,534,957 - 7,538,446 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,118,097 - 5,121,262 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1205,118,322 - 5,121,489 (-)NCBI
Celera206,550,444 - 6,553,501 (-)NCBICelera
Cytogenetic Map20p12NCBI
Zbtb22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554371,867,834 - 1,869,066 (-)NCBIChiLan1.0ChiLan1.0
ZBTB22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2547,792,318 - 47,795,676 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1643,663,980 - 43,667,336 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,886,710 - 32,890,071 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1634,000,220 - 34,003,874 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl634,000,820 - 34,002,724 (-)Ensemblpanpan1.1panPan2
ZBTB22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,751,959 - 2,755,629 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,752,533 - 2,754,524 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,832,832 - 2,836,512 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0123,083,393 - 3,087,072 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl123,083,967 - 3,085,889 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1122,750,578 - 2,754,258 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,831,891 - 2,835,570 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,906,801 - 2,910,480 (-)NCBIUU_Cfam_GSD_1.0
Zbtb22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,405,927 - 38,409,511 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,550,813 - 25,554,351 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647625,551,796 - 25,554,351 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZBTB22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl729,673,027 - 29,675,593 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1729,673,006 - 29,676,614 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2734,176,761 - 34,180,371 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZBTB22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11738,759,542 - 38,762,882 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1738,760,379 - 38,762,277 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604433,149,219 - 33,152,558 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zbtb22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,509,668 - 23,512,414 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475423,509,661 - 23,512,909 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZBTB22
16 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001141969.1(DAXX):c.210C>T (p.Phe70=) single nucleotide variant Malignant melanoma [RCV000067317] Chr6:33321565 [GRCh38]
Chr6:33289342 [GRCh37]
Chr6:33397320 [NCBI36]
Chr6:6p21.32		 not provided
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3		 pathogenic
GRCh37/hg19 6p21.32(chr6:33256191-33400523)x3 copy number gain Breast ductal adenocarcinoma [RCV000207216] Chr6:33256191..33400523 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.928A>G (p.Thr310Ala) single nucleotide variant not specified [RCV000455781] Chr6:33315989 [GRCh38]
Chr6:33283766 [GRCh37]
Chr6:6p21.32		 benign
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1		 pathogenic
NC_000006.11:g.(?_33131435)_(33419703_?)dup duplication Intellectual disability, autosomal dominant 5 [RCV000817954] Chr6:33163658..33451926 [GRCh38]
Chr6:33131435..33419703 [GRCh37]
Chr6:6p21.32		 uncertain significance
NC_000006.12:g.(?_33173681)_(33451926_?)dup duplication Intellectual disability, autosomal dominant 5 [RCV001032258] Chr6:33141458..33419703 [GRCh37]
Chr6:6p21.32		 uncertain significance
GRCh37/hg19 6p21.33-21.31(chr6:31036397-34088832)x3 copy number gain not provided [RCV001005791] Chr6:31036397..34088832 [GRCh37]
Chr6:6p21.33-21.31		 likely pathogenic
GRCh37/hg19 6p21.32-21.31(chr6:33069892-33751391) copy number gain not specified [RCV002053566] Chr6:33069892..33751391 [GRCh37]
Chr6:6p21.32-21.31		 uncertain significance
NM_005453.5(ZBTB22):c.946G>T (p.Asp316Tyr) single nucleotide variant not specified [RCV004219837] Chr6:33315971 [GRCh38]
Chr6:33283748 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.587G>A (p.Arg196Gln) single nucleotide variant not specified [RCV004220719] Chr6:33316330 [GRCh38]
Chr6:33284107 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1243C>T (p.Pro415Ser) single nucleotide variant not specified [RCV004188160] Chr6:33315674 [GRCh38]
Chr6:33283451 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1723G>A (p.Val575Ile) single nucleotide variant not specified [RCV004206578] Chr6:33315194 [GRCh38]
Chr6:33282971 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1774T>A (p.Ser592Thr) single nucleotide variant not specified [RCV004077245] Chr6:33315143 [GRCh38]
Chr6:33282920 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1394G>A (p.Gly465Asp) single nucleotide variant not specified [RCV004094470] Chr6:33315523 [GRCh38]
Chr6:33283300 [GRCh37]
Chr6:6p21.32		 uncertain significance
NC_000006.11:g.(?_32148920)_(36953949_?)dup duplication not provided [RCV003154914] Chr6:32148920..36953949 [GRCh37]
Chr6:6p21.32-21.2		 uncertain significance
NC_000006.11:g.(?_30695893)_(36953949_?)dup duplication Proteasome-associated autoinflammatory syndrome 1 [RCV003113679] Chr6:30695893..36953949 [GRCh37]
Chr6:6p21.33-21.2		 uncertain significance
NM_005453.5(ZBTB22):c.1336G>A (p.Gly446Arg) single nucleotide variant not specified [RCV004285398] Chr6:33315581 [GRCh38]
Chr6:33283358 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1399C>T (p.Pro467Ser) single nucleotide variant not specified [RCV004270191] Chr6:33315518 [GRCh38]
Chr6:33283295 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1891G>A (p.Gly631Arg) single nucleotide variant not specified [RCV004280046] Chr6:33315026 [GRCh38]
Chr6:33282803 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1222G>C (p.Ala408Pro) single nucleotide variant not specified [RCV004336508] Chr6:33315695 [GRCh38]
Chr6:33283472 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1018C>G (p.Leu340Val) single nucleotide variant not specified [RCV004315598] Chr6:33315899 [GRCh38]
Chr6:33283676 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1070G>A (p.Ser357Asn) single nucleotide variant not specified [RCV004317605] Chr6:33315847 [GRCh38]
Chr6:33283624 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1826C>T (p.Pro609Leu) single nucleotide variant not specified [RCV004361998] Chr6:33315091 [GRCh38]
Chr6:33282868 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1702C>T (p.Arg568Cys) single nucleotide variant not specified [RCV004346577] Chr6:33315215 [GRCh38]
Chr6:33282992 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1162G>A (p.Glu388Lys) single nucleotide variant not specified [RCV004478824] Chr6:33315755 [GRCh38]
Chr6:33283532 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1172G>T (p.Gly391Val) single nucleotide variant not specified [RCV004478825] Chr6:33315745 [GRCh38]
Chr6:33283522 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1287C>G (p.Phe429Leu) single nucleotide variant not specified [RCV004478826] Chr6:33315630 [GRCh38]
Chr6:33283407 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1389C>G (p.Ser463Arg) single nucleotide variant not specified [RCV004478827] Chr6:33315528 [GRCh38]
Chr6:33283305 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1427G>A (p.Gly476Glu) single nucleotide variant not specified [RCV004478828] Chr6:33315490 [GRCh38]
Chr6:33283267 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_005453.5(ZBTB22):c.1888G>C (p.Gly630Arg) single nucleotide variant not specified [RCV004478830] Chr6:33315029 [GRCh38]
Chr6:33282806 [GRCh37]
Chr6:6p21.32		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1378
Count of miRNA genes:598
Interacting mature miRNAs:680
Transcripts:ENST00000418724, ENST00000431845, ENST00000441117
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
ZNF297_8921  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37633,282,189 - 33,282,836UniSTSGRCh37
Build 36633,390,167 - 33,390,814RGDNCBI36
Celera634,836,554 - 34,837,201RGD
HuRef633,023,759 - 33,024,406UniSTS
RH37250  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37633,282,248 - 33,282,465UniSTSGRCh37
Build 36633,390,226 - 33,390,443RGDNCBI36
Celera634,836,613 - 34,836,830RGD
Cytogenetic Map6p21.3UniSTS
HuRef633,023,818 - 33,024,035UniSTS
GeneMap99-GB4 RH Map6120.03UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2248 1879 1391 305 1507 151 3599 1013 2772 354 1387 1599 171 1 1117 2073 5
Low 191 1112 335 319 440 314 758 1184 962 65 73 14 4 87 715 1 2
Below cutoff 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_009876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001145338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_005453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK095978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ002626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX248088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX459194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD369813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA625357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA777388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z97183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z97184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000418724   ⟹   ENSP00000404403
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl633,314,406 - 33,317,942 (-)Ensembl
RefSeq Acc Id: ENST00000431845   ⟹   ENSP00000407545
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl633,314,418 - 33,317,744 (-)Ensembl
RefSeq Acc Id: ENST00000441117   ⟹   ENSP00000413172
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl633,316,469 - 33,317,941 (-)Ensembl
RefSeq Acc Id: NM_001145338   ⟹   NP_001138810
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38633,314,418 - 33,317,942 (-)NCBI
GRCh37633,282,182 - 33,285,719 (-)RGD
Celera634,836,547 - 34,840,085 (-)RGD
HuRef633,023,752 - 33,027,291 (-)RGD
CHM1_1633,284,116 - 33,287,635 (-)NCBI
T2T-CHM13v2.0633,135,780 - 33,139,304 (-)NCBI
Sequence:
RefSeq Acc Id: NM_005453   ⟹   NP_005444
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38633,314,418 - 33,317,744 (-)NCBI
GRCh37633,282,182 - 33,285,719 (-)RGD
Build 36633,390,173 - 33,393,472 (-)NCBI Archive
Celera634,836,547 - 34,840,085 (-)RGD
HuRef633,023,752 - 33,027,291 (-)RGD
CHM1_1633,284,116 - 33,287,428 (-)NCBI
T2T-CHM13v2.0633,135,780 - 33,139,106 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001138810   ⟸   NM_001145338
- UniProtKB: Q8WV82 (UniProtKB/Swiss-Prot),   Q5STR7 (UniProtKB/Swiss-Prot),   Q5STL0 (UniProtKB/Swiss-Prot),   Q5HYV4 (UniProtKB/Swiss-Prot),   B0V007 (UniProtKB/Swiss-Prot),   O15209 (UniProtKB/Swiss-Prot),   A0A1U9X8V3 (UniProtKB/TrEMBL),   A0A1U9X8U9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_005444   ⟸   NM_005453
- UniProtKB: Q8WV82 (UniProtKB/Swiss-Prot),   Q5STR7 (UniProtKB/Swiss-Prot),   Q5STL0 (UniProtKB/Swiss-Prot),   Q5HYV4 (UniProtKB/Swiss-Prot),   B0V007 (UniProtKB/Swiss-Prot),   O15209 (UniProtKB/Swiss-Prot),   A0A1U9X8V3 (UniProtKB/TrEMBL),   A0A1U9X8U9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000413172   ⟸   ENST00000441117
RefSeq Acc Id: ENSP00000404403   ⟸   ENST00000418724
RefSeq Acc Id: ENSP00000407545   ⟸   ENST00000431845
Protein Domains
BTB   C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O15209-F1-model_v2 AlphaFold O15209 1-634 view protein structure

Promoters
RGD ID:6872932
Promoter ID:EPDNEW_H9599
Type:multiple initiation site
Name:ZBTB22_1
Description:zinc finger and BTB domain containing 22
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9600  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38633,317,744 - 33,317,804EPDNEW
RGD ID:6872870
Promoter ID:EPDNEW_H9600
Type:initiation region
Name:ZBTB22_2
Description:zinc finger and BTB domain containing 22
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9599  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38633,318,046 - 33,318,106EPDNEW
RGD ID:6805028
Promoter ID:HG_KWN:53193
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid
Transcripts:UC010JUV.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36633,390,791 - 33,391,522 (-)MPROMDB
RGD ID:6805026
Promoter ID:HG_KWN:53194
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001145338,   NM_005453
Position:
Human AssemblyChrPosition (strand)Source
Build 36633,393,591 - 33,394,627 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:13085 AgrOrtholog
COSMIC ZBTB22 COSMIC
Ensembl Genes ENSG00000206280 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000227780 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000229253 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000236104 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000237056 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000383196.4 UniProtKB/Swiss-Prot
  ENST00000416097.2 UniProtKB/Swiss-Prot
  ENST00000418540.2 UniProtKB/Swiss-Prot
  ENST00000418724 ENTREZGENE
  ENST00000418724.1 UniProtKB/Swiss-Prot
  ENST00000426244.1 UniProtKB/TrEMBL
  ENST00000431845 ENTREZGENE
  ENST00000431845.3 UniProtKB/Swiss-Prot
  ENST00000436352.1 UniProtKB/TrEMBL
  ENST00000441117.1 UniProtKB/TrEMBL
  ENST00000445320.2 UniProtKB/Swiss-Prot
  ENST00000448500.1 UniProtKB/TrEMBL
  ENST00000454866.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000206280 GTEx
  ENSG00000227780 GTEx
  ENSG00000229253 GTEx
  ENSG00000236104 GTEx
  ENSG00000237056 GTEx
HGNC ID HGNC:13085 ENTREZGENE
Human Proteome Map ZBTB22 Human Proteome Map
InterPro BTB/POZ_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:9278 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 9278 ENTREZGENE
OMIM 611439 OMIM
PANTHER AGAP004733-PA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37661 PharmGKB
PROSITE BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1U9X8U9 ENTREZGENE, UniProtKB/TrEMBL
  A0A1U9X8V3 ENTREZGENE, UniProtKB/TrEMBL
  A2AB93_HUMAN UniProtKB/TrEMBL
  B0V007 ENTREZGENE
  O15209 ENTREZGENE
  Q5HYV4 ENTREZGENE
  Q5STL0 ENTREZGENE
  Q5STR7 ENTREZGENE
  Q8WV82 ENTREZGENE
  ZBT22_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B0V007 UniProtKB/Swiss-Prot
  Q5HYV4 UniProtKB/Swiss-Prot
  Q5STL0 UniProtKB/Swiss-Prot
  Q5STR7 UniProtKB/Swiss-Prot
  Q8WV82 UniProtKB/Swiss-Prot