SERTAD4 (SERTA domain containing 4) - Rat Genome Database

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Gene: SERTAD4 (SERTA domain containing 4) Homo sapiens
Analyze
Symbol: SERTAD4
Name: SERTA domain containing 4
RGD ID: 1351903
HGNC Page HGNC:25236
Description: Predicted to be located in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DJ667H12.2; SERTA domain-containing protein 4
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,232,796 - 210,246,631 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,232,796 - 210,246,631 (+)EnsemblGRCh38hg38GRCh38
GRCh371210,406,141 - 210,419,976 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361208,472,818 - 208,483,083 (+)NCBINCBI36Build 36hg18NCBI36
Build 341206,794,589 - 206,804,833NCBI
Celera1183,629,578 - 183,639,844 (+)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1181,079,983 - 181,090,160 (+)NCBIHuRef
CHM1_11211,678,522 - 211,688,788 (+)NCBICHM1_1
T2T-CHM13v2.01209,471,480 - 209,485,315 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14702039   PMID:15342556   PMID:19156129   PMID:19322201   PMID:20368287   PMID:21664411   PMID:26186194   PMID:28065597   PMID:28330616   PMID:28514442   PMID:30021884   PMID:32814053  
PMID:33961781  


Genomics

Comparative Map Data
SERTAD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,232,796 - 210,246,631 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,232,796 - 210,246,631 (+)EnsemblGRCh38hg38GRCh38
GRCh371210,406,141 - 210,419,976 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361208,472,818 - 208,483,083 (+)NCBINCBI36Build 36hg18NCBI36
Build 341206,794,589 - 206,804,833NCBI
Celera1183,629,578 - 183,639,844 (+)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1181,079,983 - 181,090,160 (+)NCBIHuRef
CHM1_11211,678,522 - 211,688,788 (+)NCBICHM1_1
T2T-CHM13v2.01209,471,480 - 209,485,315 (+)NCBIT2T-CHM13v2.0
Sertad4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391192,526,796 - 192,538,060 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1192,526,796 - 192,538,064 (-)EnsemblGRCm39 Ensembl
GRCm381192,844,469 - 192,855,752 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1192,844,488 - 192,855,756 (-)EnsemblGRCm38mm10GRCm38
MGSCv371194,670,682 - 194,681,946 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361194,545,212 - 194,556,445 (-)NCBIMGSCv36mm8
Celera1199,726,389 - 199,737,652 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.55NCBI
Sertad4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813106,889,019 - 106,899,777 (-)NCBIGRCr8
mRatBN7.213104,360,307 - 104,371,064 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13104,360,307 - 104,370,546 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13106,877,959 - 106,888,198 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013108,261,816 - 108,272,055 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013105,479,767 - 105,490,006 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013111,574,545 - 111,585,113 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13111,574,609 - 111,581,019 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,126,511 - 116,136,873 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413108,739,942 - 108,750,295 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera13103,790,786 - 103,801,020 (-)NCBICelera
Cytogenetic Map13q27NCBI
Sertad4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554891,947,045 - 1,953,970 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554891,947,819 - 1,958,434 (-)NCBIChiLan1.0ChiLan1.0
SERTAD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2139,168,286 - 39,181,958 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1139,134,527 - 39,148,088 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01185,789,513 - 185,803,679 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11190,663,690 - 190,672,669 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1190,663,690 - 190,672,666 (+)Ensemblpanpan1.1panPan2
SERTAD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.178,856,298 - 8,862,280 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl78,856,330 - 8,860,526 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha78,434,005 - 8,445,065 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.078,552,165 - 8,563,192 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl78,551,640 - 8,562,943 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.178,481,124 - 8,492,152 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.078,577,879 - 8,588,924 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.078,714,991 - 8,726,067 (+)NCBIUU_Cfam_GSD_1.0
Sertad4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934465,648,427 - 65,655,846 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365572,888,473 - 2,895,492 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365572,888,574 - 2,895,867 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERTAD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9132,737,299 - 132,748,448 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19132,737,291 - 132,748,443 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29145,772,676 - 145,783,649 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SERTAD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12519,224,996 - 19,238,427 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2519,224,806 - 19,233,425 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605519,787,524 - 19,800,998 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sertad4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248071,751,506 - 1,760,634 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SERTAD4
19 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q31.1-42.11(chr1:187143981-224299417)x3 copy number gain See cases [RCV000051857] Chr1:187143981..224299417 [GRCh38]
Chr1:187113113..224487119 [GRCh37]
Chr1:185379736..222553742 [NCBI36]
Chr1:1q31.1-42.11		 pathogenic
GRCh38/hg38 1q32.2-44(chr1:209646207-248931113)x3 copy number gain See cases [RCV000051861] Chr1:209646207..248931113 [GRCh38]
Chr1:209819552..249225312 [GRCh37]
Chr1:207886175..247191935 [NCBI36]
Chr1:1q32.2-44		 pathogenic
GRCh38/hg38 1q32.2-44(chr1:209963625-248918469)x3 copy number gain See cases [RCV000134979] Chr1:209963625..248918469 [GRCh38]
Chr1:210136970..249212668 [GRCh37]
Chr1:208203593..247179291 [NCBI36]
Chr1:1q32.2-44		 pathogenic
GRCh38/hg38 1q32.2-32.3(chr1:208063461-211907812)x1 copy number loss See cases [RCV000138122] Chr1:208063461..211907812 [GRCh38]
Chr1:208236806..212081154 [GRCh37]
Chr1:206303429..210147777 [NCBI36]
Chr1:1q32.2-32.3		 likely benign
GRCh38/hg38 1q32.1-42.12(chr1:204764914-225408698)x3 copy number gain See cases [RCV000142054] Chr1:204764914..225408698 [GRCh38]
Chr1:204734042..225596400 [GRCh37]
Chr1:203000665..223663023 [NCBI36]
Chr1:1q32.1-42.12		 pathogenic
GRCh38/hg38 1q32.2-44(chr1:207346642-248930485)x3 copy number gain See cases [RCV000143727] Chr1:207346642..248930485 [GRCh38]
Chr1:207519987..249224684 [GRCh37]
Chr1:205586610..247191307 [NCBI36]
Chr1:1q32.2-44		 pathogenic
GRCh37/hg19 1q31.3-42.13(chr1:197811907-228997888)x3 copy number gain See cases [RCV000240137] Chr1:197811907..228997888 [GRCh37]
Chr1:1q31.3-42.13		 pathogenic
GRCh37/hg19 1q31.3-44(chr1:195483439-249213000)x3 copy number gain See cases [RCV000449172] Chr1:195483439..249213000 [GRCh37]
Chr1:1q31.3-44		 pathogenic
GRCh37/hg19 1q32.2(chr1:209742722-210774573)x1 copy number loss See cases [RCV000446748] Chr1:209742722..210774573 [GRCh37]
Chr1:1q32.2		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1q32.1-32.3(chr1:204682513-212815646) copy number loss Global developmental delay [RCV000626524] Chr1:204682513..212815646 [GRCh37]
Chr1:1q32.1-32.3		 pathogenic
GRCh37/hg19 1q32.2(chr1:210026523-211033868)x3 copy number gain not provided [RCV000684693] Chr1:210026523..211033868 [GRCh37]
Chr1:1q32.2		 uncertain significance
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1q25.3-41(chr1:185644663-221698833)x3 copy number gain not provided [RCV000749265] Chr1:185644663..221698833 [GRCh37]
Chr1:1q25.3-41		 pathogenic
GRCh37/hg19 1q32.2(chr1:210400669-210722770)x1 copy number loss not provided [RCV001005169] Chr1:210400669..210722770 [GRCh37]
Chr1:1q32.2		 uncertain significance
GRCh37/hg19 1q25.3-44(chr1:182388773-249111240)x3 copy number gain not provided [RCV000845852] Chr1:182388773..249111240 [GRCh37]
Chr1:1q25.3-44		 pathogenic
GRCh37/hg19 1q32.1-32.3(chr1:206329070-213263817)x3 copy number gain not provided [RCV000848713] Chr1:206329070..213263817 [GRCh37]
Chr1:1q32.1-32.3		 uncertain significance
GRCh37/hg19 1q32.2-44(chr1:210152794-249218992)x3 copy number gain See cases [RCV001194578] Chr1:210152794..249218992 [GRCh37]
Chr1:1q32.2-44		 pathogenic
GRCh37/hg19 1q32.1-44(chr1:204045948-249218992)x3 copy number gain See cases [RCV001007407] Chr1:204045948..249218992 [GRCh37]
Chr1:1q32.1-44		 pathogenic
GRCh37/hg19 1q31.3-32.2(chr1:194356425-210988710)x3 copy number gain not provided [RCV001249273] Chr1:194356425..210988710 [GRCh37]
Chr1:1q31.3-32.2		 not provided
NC_000001.10:g.(?_130980840)_(248900000_?)dup duplication Gastrointestinal stromal tumor [RCV001300221]|Parathyroid carcinoma [RCV001341077] Chr1:130980840..248900000 [GRCh37]
Chr1:1q12-44		 uncertain significance
GRCh37/hg19 1q31.3-44(chr1:197867914-249224684)x3 copy number gain See cases [RCV002287837] Chr1:197867914..249224684 [GRCh37]
Chr1:1q31.3-44		 pathogenic
NM_019605.5(SERTAD4):c.741T>A (p.Asp247Glu) single nucleotide variant Inborn genetic diseases [RCV002753328] Chr1:210242007 [GRCh38]
Chr1:210415352 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.71G>A (p.Gly24Glu) single nucleotide variant Inborn genetic diseases [RCV002794351] Chr1:210238031 [GRCh38]
Chr1:210411376 [GRCh37]
Chr1:1q32.2		 uncertain significance
GRCh38/hg38 1q32.2-42.13(chr1:228006998-228061271)x2 copy number loss Orofacial cleft 2 [RCV002481175] Chr1:228006998..228061271 [GRCh38]
Chr1:1q32.2-42.13		 association
GRCh37/hg19 1q25.3-32.3(chr1:181453460-213107248)x3 copy number gain not provided [RCV002475637] Chr1:181453460..213107248 [GRCh37]
Chr1:1q25.3-32.3		 pathogenic
NM_019605.5(SERTAD4):c.358G>A (p.Asp120Asn) single nucleotide variant Inborn genetic diseases [RCV002946753] Chr1:210241624 [GRCh38]
Chr1:210414969 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.958A>T (p.Thr320Ser) single nucleotide variant Inborn genetic diseases [RCV003000748] Chr1:210242224 [GRCh38]
Chr1:210415569 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.110C>T (p.Pro37Leu) single nucleotide variant Inborn genetic diseases [RCV002929757] Chr1:210238070 [GRCh38]
Chr1:210411415 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.652T>C (p.Ser218Pro) single nucleotide variant Inborn genetic diseases [RCV002850401] Chr1:210241918 [GRCh38]
Chr1:210415263 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.538A>G (p.Lys180Glu) single nucleotide variant Inborn genetic diseases [RCV002787659] Chr1:210241804 [GRCh38]
Chr1:210415149 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.601A>G (p.Asn201Asp) single nucleotide variant Inborn genetic diseases [RCV002849642] Chr1:210241867 [GRCh38]
Chr1:210415212 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.185A>G (p.Tyr62Cys) single nucleotide variant Inborn genetic diseases [RCV002665286] Chr1:210239502 [GRCh38]
Chr1:210412847 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.823G>A (p.Val275Ile) single nucleotide variant Inborn genetic diseases [RCV002891565] Chr1:210242089 [GRCh38]
Chr1:210415434 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.872A>G (p.Asn291Ser) single nucleotide variant Inborn genetic diseases [RCV002915128] Chr1:210242138 [GRCh38]
Chr1:210415483 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.154G>A (p.Gly52Arg) single nucleotide variant Inborn genetic diseases [RCV002769978] Chr1:210238114 [GRCh38]
Chr1:210411459 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.521A>C (p.Lys174Thr) single nucleotide variant Inborn genetic diseases [RCV002920635] Chr1:210241787 [GRCh38]
Chr1:210415132 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.314G>A (p.Arg105Gln) single nucleotide variant Inborn genetic diseases [RCV002723318] Chr1:210241580 [GRCh38]
Chr1:210414925 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.700C>T (p.Pro234Ser) single nucleotide variant Inborn genetic diseases [RCV003220254] Chr1:210241966 [GRCh38]
Chr1:210415311 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.623C>T (p.Ala208Val) single nucleotide variant Inborn genetic diseases [RCV003190723] Chr1:210241889 [GRCh38]
Chr1:210415234 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.166C>G (p.Pro56Ala) single nucleotide variant Inborn genetic diseases [RCV003376428] Chr1:210238126 [GRCh38]
Chr1:210411471 [GRCh37]
Chr1:1q32.2		 uncertain significance
NM_019605.5(SERTAD4):c.1057G>A (p.Gly353Arg) single nucleotide variant Inborn genetic diseases [RCV003370003] Chr1:210242323 [GRCh38]
Chr1:210415668 [GRCh37]
Chr1:1q32.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1687
Count of miRNA genes:890
Interacting mature miRNAs:1060
Transcripts:ENST00000367012, ENST00000482421, ENST00000483884, ENST00000490620
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-76290  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,416,279 - 210,416,428UniSTSGRCh37
Build 361208,482,902 - 208,483,051RGDNCBI36
Celera1183,639,663 - 183,639,812RGD
Cytogenetic Map1q32.1-q41UniSTS
HuRef1181,089,979 - 181,090,128UniSTS
TNG Radiation Hybrid Map141608.0UniSTS
GeneMap99-GB4 RH Map1689.33UniSTS
Whitehead-RH Map1841.0UniSTS
RH92965  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,415,714 - 210,415,868UniSTSGRCh37
Build 361208,482,337 - 208,482,491RGDNCBI36
Celera1183,639,098 - 183,639,252RGD
Cytogenetic Map1q32.1-q41UniSTS
HuRef1181,089,414 - 181,089,568UniSTS
GeneMap99-GB4 RH Map1689.33UniSTS
RH102282  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,404,881 - 210,405,047UniSTSGRCh37
Build 361208,471,504 - 208,471,670RGDNCBI36
Celera1183,628,264 - 183,628,430RGD
Cytogenetic Map1q32.1-q41UniSTS
Cytogenetic Map1q32.2UniSTS
HuRef1181,078,899 - 181,079,065UniSTS
GeneMap99-GB4 RH Map1689.26UniSTS
SHGC-76284  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,411,325 - 210,411,450UniSTSGRCh37
Build 361208,477,948 - 208,478,073RGDNCBI36
Celera1183,634,708 - 183,634,833RGD
Cytogenetic Map1q32.1-q41UniSTS
HuRef1181,085,025 - 181,085,150UniSTS
TNG Radiation Hybrid Map141604.0UniSTS
GeneMap99-GB4 RH Map1689.16UniSTS
SERTAD4_3610  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,415,720 - 210,416,505UniSTSGRCh37
Build 361208,482,343 - 208,483,128RGDNCBI36
Celera1183,639,104 - 183,639,889RGD
HuRef1181,089,420 - 181,090,205UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 216 187 10 68 12 8 188 17 114 58 173 163 67 3 109 2
Low 2013 1853 1033 140 166 42 3354 1254 3334 300 1100 1410 106 1 1128 1908 2 1
Below cutoff 183 561 581 322 769 322 803 904 285 61 179 37 2 73 762 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001354173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001375428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047425536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054337727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_921894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI808539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK021425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK096381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL035414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW340609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP342499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000367012   ⟹   ENSP00000355979
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,232,796 - 210,246,255 (+)Ensembl
RefSeq Acc Id: ENST00000482421
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,237,943 - 210,246,628 (+)Ensembl
RefSeq Acc Id: ENST00000483884
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,237,978 - 210,246,631 (+)Ensembl
RefSeq Acc Id: ENST00000490620
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,237,282 - 210,242,165 (+)Ensembl
RefSeq Acc Id: NM_001354173   ⟹   NP_001341102
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,232,796 - 210,246,631 (+)NCBI
T2T-CHM13v2.01209,471,480 - 209,485,315 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001375428   ⟹   NP_001362357
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,237,286 - 210,246,255 (+)NCBI
T2T-CHM13v2.01209,475,970 - 209,484,939 (+)NCBI
Sequence:
RefSeq Acc Id: NM_019605   ⟹   NP_062551
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,232,796 - 210,246,255 (+)NCBI
GRCh371210,406,195 - 210,420,252 (+)NCBI
Build 361208,472,818 - 208,483,083 (+)NCBI Archive
Celera1183,629,578 - 183,639,844 (+)RGD
HuRef1181,079,983 - 181,090,160 (+)ENTREZGENE
CHM1_11211,678,522 - 211,688,788 (+)NCBI
T2T-CHM13v2.01209,471,480 - 209,484,939 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047425536   ⟹   XP_047281492
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,237,286 - 210,246,631 (+)NCBI
RefSeq Acc Id: XM_054337727   ⟹   XP_054193702
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01209,475,970 - 209,485,315 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_062551   ⟸   NM_019605
- Peptide Label: isoform 1
- UniProtKB: B2RD32 (UniProtKB/Swiss-Prot),   Q9NUC0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001341102   ⟸   NM_001354173
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: NP_001362357   ⟸   NM_001375428
- Peptide Label: isoform 1
- UniProtKB: Q9NUC0 (UniProtKB/Swiss-Prot),   B2RD32 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSP00000355979   ⟸   ENST00000367012
RefSeq Acc Id: XP_047281492   ⟸   XM_047425536
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054193702   ⟸   XM_054337727
- Peptide Label: isoform X1
Protein Domains
SERTA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NUC0-F1-model_v2 AlphaFold Q9NUC0 1-356 view protein structure

Promoters
RGD ID:6858884
Promoter ID:EPDNEW_H2607
Type:initiation region
Name:SERTAD4_2
Description:SERTA domain containing 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2608  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,232,679 - 210,232,739EPDNEW
RGD ID:6858886
Promoter ID:EPDNEW_H2608
Type:initiation region
Name:SERTAD4_1
Description:SERTA domain containing 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2607  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,232,802 - 210,232,862EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:25236 AgrOrtholog
COSMIC SERTAD4 COSMIC
Ensembl Genes ENSG00000082497 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000281230 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000367012 ENTREZGENE
  ENST00000367012.4 UniProtKB/Swiss-Prot
  ENST00000630425.2 UniProtKB/Swiss-Prot
GTEx ENSG00000082497 GTEx
  ENSG00000281230 GTEx
HGNC ID HGNC:25236 ENTREZGENE
Human Proteome Map SERTAD4 Human Proteome Map
InterPro SERTA_dom UniProtKB/Swiss-Prot
  SERTAD4 UniProtKB/Swiss-Prot
KEGG Report hsa:56256 UniProtKB/Swiss-Prot
NCBI Gene 56256 ENTREZGENE
PANTHER PTHR14272 UniProtKB/Swiss-Prot
  SERTA DOMAIN-CONTAINING PROTEIN 4 UniProtKB/Swiss-Prot
Pfam SERTA UniProtKB/Swiss-Prot
PharmGKB PA134897438 PharmGKB
PROSITE SERTA UniProtKB/Swiss-Prot
UniProt B2RD32 ENTREZGENE
  Q9NUC0 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B2RD32 UniProtKB/Swiss-Prot