RAB15 (RAB15, member RAS oncogene family) - Rat Genome Database

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Gene: RAB15 (RAB15, member RAS oncogene family) Homo sapiens
Analyze
Symbol: RAB15
Name: RAB15, member RAS oncogene family
RGD ID: 1351715
HGNC Page HGNC:20150
Description: Predicted to enable GTP binding activity and GTPase activity. Involved in positive regulation of regulated secretory pathway. Located in cilium; endosome membrane; and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: RAB15, member RAS onocogene family; ras-related protein Rab-15; Ras-related protein Rab-15 isoform AN1; Ras-related protein Rab-15 isoform AN2; Ras-related protein Rab-15 isoform AN3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381464,945,816 - 64,972,336 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1464,945,814 - 64,973,226 (-)EnsemblGRCh38hg38GRCh38
GRCh371465,412,534 - 65,439,054 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361464,482,287 - 64,508,551 (-)NCBINCBI36Build 36hg18NCBI36
Build 341464,482,287 - 64,508,551NCBI
Celera1445,467,116 - 45,493,459 (-)NCBICelera
Cytogenetic Map14q23.3NCBI
HuRef1445,582,156 - 45,608,228 (-)NCBIHuRef
CHM1_11465,350,701 - 65,377,061 (-)NCBICHM1_1
T2T-CHM13v2.01459,150,685 - 59,177,205 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10428799   PMID:10837464   PMID:11697911   PMID:12105226   PMID:12477932   PMID:12508121   PMID:12578829   PMID:15146197   PMID:15489334   PMID:16195351   PMID:17207965   PMID:17646400  
PMID:18022941   PMID:18676680   PMID:19056867   PMID:19170196   PMID:19625176   PMID:19692168   PMID:19773279   PMID:19913121   PMID:20379614   PMID:20628086   PMID:21319273   PMID:21491086  
PMID:21873635   PMID:22427180   PMID:22898364   PMID:22899725   PMID:23246001   PMID:23376485   PMID:26760575   PMID:28514442   PMID:28581483   PMID:29845934   PMID:30804014   PMID:31324722  
PMID:31436131   PMID:31536960   PMID:31586073   PMID:31732153   PMID:32176739   PMID:32694731   PMID:33961781   PMID:34316702   PMID:35256949   PMID:35871249   PMID:36526897   PMID:36574265  
PMID:36610398   PMID:38473798  


Genomics

Comparative Map Data
RAB15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381464,945,816 - 64,972,336 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1464,945,814 - 64,973,226 (-)EnsemblGRCh38hg38GRCh38
GRCh371465,412,534 - 65,439,054 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361464,482,287 - 64,508,551 (-)NCBINCBI36Build 36hg18NCBI36
Build 341464,482,287 - 64,508,551NCBI
Celera1445,467,116 - 45,493,459 (-)NCBICelera
Cytogenetic Map14q23.3NCBI
HuRef1445,582,156 - 45,608,228 (-)NCBIHuRef
CHM1_11465,350,701 - 65,377,061 (-)NCBICHM1_1
T2T-CHM13v2.01459,150,685 - 59,177,205 (-)NCBIT2T-CHM13v2.0
Rab15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391276,844,734 - 76,869,532 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1276,844,734 - 76,869,682 (-)EnsemblGRCm39 Ensembl
GRCm381276,797,960 - 76,822,759 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1276,797,960 - 76,822,908 (-)EnsemblGRCm38mm10GRCm38
MGSCv371277,898,950 - 77,923,511 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361277,716,802 - 77,741,361 (-)NCBIMGSCv36mm8
Celera1277,880,317 - 77,904,917 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1233.73NCBI
Rab15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86101,232,740 - 101,257,388 (-)NCBIGRCr8
mRatBN7.2695,499,584 - 95,524,073 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl695,499,587 - 95,523,942 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx695,888,215 - 95,912,538 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0696,186,752 - 96,211,074 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0695,615,555 - 95,639,890 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0699,845,952 - 99,870,320 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl699,845,954 - 99,870,024 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06109,242,425 - 109,266,332 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4699,378,937 - 99,403,340 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1699,382,393 - 99,406,796 (-)NCBI
Celera693,918,933 - 93,942,804 (-)NCBICelera
Cytogenetic Map6q24NCBI
Rab15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554664,958,414 - 4,981,464 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554664,958,414 - 4,981,464 (+)NCBIChiLan1.0ChiLan1.0
RAB15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21566,059,643 - 66,086,329 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11465,276,156 - 65,302,829 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01445,529,223 - 45,555,895 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11464,408,591 - 64,435,016 (-)NCBIpanpan1.1PanPan1.1panPan2
RAB15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1839,329,754 - 39,364,000 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl839,330,557 - 39,335,590 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha839,021,097 - 39,056,403 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0839,551,806 - 39,587,131 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl839,551,806 - 39,577,155 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1839,172,610 - 39,208,151 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0839,245,370 - 39,280,887 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0839,604,428 - 39,640,008 (-)NCBIUU_Cfam_GSD_1.0
Rab15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864065,569,044 - 65,598,245 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364958,596,430 - 8,622,661 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364958,590,844 - 8,622,655 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl789,015,042 - 89,039,482 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1789,015,041 - 89,039,482 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2795,395,973 - 95,402,824 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAB15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12442,160,949 - 42,185,098 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2442,158,271 - 42,185,082 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605330,328,691 - 30,374,327 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473436,062,329 - 36,084,049 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473436,062,726 - 36,083,841 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RAB15
7 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 14q23.1-23.3(chr14:59917051-66750803)x1 copy number loss See cases [RCV000050892] Chr14:59917051..66750803 [GRCh38]
Chr14:60383769..67217521 [GRCh37]
Chr14:59453522..66287274 [NCBI36]
Chr14:14q23.1-23.3		 pathogenic
GRCh38/hg38 14q22.3-23.3(chr14:57041036-67208231)x1 copy number loss See cases [RCV000051521] Chr14:57041036..67208231 [GRCh38]
Chr14:57507754..67674948 [GRCh37]
Chr14:56577507..66744701 [NCBI36]
Chr14:14q22.3-23.3		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q23.3(chr14:64952923-66295289)x3 copy number gain See cases [RCV000136999] Chr14:64952923..66295289 [GRCh38]
Chr14:65419641..66762007 [GRCh37]
Chr14:64489394..65831760 [NCBI36]
Chr14:14q23.3		 uncertain significance
GRCh38/hg38 14q23.2-23.3(chr14:62252700-65753416)x1 copy number loss See cases [RCV000138250] Chr14:62252700..65753416 [GRCh38]
Chr14:62719418..66220134 [GRCh37]
Chr14:61789171..65289887 [NCBI36]
Chr14:14q23.2-23.3		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19794561-107234280)x3 copy number gain See cases [RCV000446256] Chr14:19794561..107234280 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q23.2-32.33(chr14:62493932-107285437)x3 copy number gain See cases [RCV000448557] Chr14:62493932..107285437 [GRCh37]
Chr14:14q23.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:20511673-107285437) copy number gain See cases [RCV000512041] Chr14:20511673..107285437 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.1-32.33(chr14:19000422-107289053)x3 copy number gain not provided [RCV000738412] Chr14:19000422..107289053 [GRCh37]
Chr14:14q11.1-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19280733-107287663)x3 copy number gain not provided [RCV000738413] Chr14:19280733..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19327823-107287663)x3 copy number gain not provided [RCV000738414] Chr14:19327823..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q23.1-23.3(chr14:61409856-65742610)x3 copy number gain not provided [RCV001259780] Chr14:61409856..65742610 [GRCh37]
Chr14:14q23.1-23.3		 likely pathogenic
GRCh37/hg19 14q23.2-23.3(chr14:64016496-65834490)x3 copy number gain See cases [RCV002285053] Chr14:64016496..65834490 [GRCh37]
Chr14:14q23.2-23.3		 uncertain significance
GRCh37/hg19 14q22.2-24.3(chr14:54654001-75828024)x3 copy number gain 14q22.2q24.3 duplication [RCV001506967] Chr14:54654001..75828024 [GRCh37]
Chr14:14q22.2-24.3		 likely pathogenic
NC_000014.8:g.(?_64746679)_(66975329_?)del deletion Sulfite oxidase deficiency due to molybdenum cofactor deficiency type C [RCV002007295] Chr14:64746679..66975329 [GRCh37]
Chr14:14q23.2-23.3		 pathogenic
GRCh37/hg19 14q13.3-32.33(chr14:37671058-106985955)x2 copy number gain See cases [RCV002286356] Chr14:37671058..106985955 [GRCh37]
Chr14:14q13.3-32.33		 pathogenic
NM_001308154.2(RAB15):c.327C>T (p.Tyr109=) single nucleotide variant not specified [RCV004076058] Chr14:64950412 [GRCh38]
Chr14:65417130 [GRCh37]
Chr14:14q23.3		 likely benign
NM_001308154.2(RAB15):c.79C>G (p.Arg27Gly) single nucleotide variant not specified [RCV004182369] Chr14:64971998 [GRCh38]
Chr14:65438716 [GRCh37]
Chr14:14q23.3		 uncertain significance
NM_001308154.2(RAB15):c.299T>C (p.Met100Thr) single nucleotide variant not specified [RCV004317369] Chr14:64951099 [GRCh38]
Chr14:65417817 [GRCh37]
Chr14:14q23.3		 uncertain significance
NM_001308154.2(RAB15):c.19G>A (p.Val7Met) single nucleotide variant not specified [RCV004279186] Chr14:64972058 [GRCh38]
Chr14:65438776 [GRCh37]
Chr14:14q23.3		 uncertain significance
GRCh37/hg19 14q23.1-32.33(chr14:58894502-107227240)x3 copy number gain not provided [RCV003485036] Chr14:58894502..107227240 [GRCh37]
Chr14:14q23.1-32.33		 pathogenic
GRCh37/hg19 14q22.3-24.1(chr14:57588965-68334517)x3 copy number gain not provided [RCV003485034] Chr14:57588965..68334517 [GRCh37]
Chr14:14q22.3-24.1		 likely pathogenic
NM_001308154.2(RAB15):c.100C>T (p.His34Tyr) single nucleotide variant not specified [RCV004443017] Chr14:64971977 [GRCh38]
Chr14:65438695 [GRCh37]
Chr14:14q23.3		 uncertain significance
NM_001308154.2(RAB15):c.324+23C>T single nucleotide variant not specified [RCV004443019] Chr14:64951051 [GRCh38]
Chr14:65417769 [GRCh37]
Chr14:14q23.3		 likely benign
NM_001308154.2(RAB15):c.470A>G (p.Asn157Ser) single nucleotide variant not specified [RCV004443020] Chr14:64948678 [GRCh38]
Chr14:65415396 [GRCh37]
Chr14:14q23.3		 uncertain significance
NM_001308154.2(RAB15):c.316G>A (p.Val106Met) single nucleotide variant not specified [RCV004443018] Chr14:64951082 [GRCh38]
Chr14:65417800 [GRCh37]
Chr14:14q23.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:7202
Count of miRNA genes:1078
Interacting mature miRNAs:1338
Transcripts:ENST00000267512, ENST00000426039, ENST00000436278, ENST00000533601, ENST00000554593, ENST00000555256, ENST00000585059
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH76749  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371465,412,566 - 65,412,781UniSTSGRCh37
Build 361464,482,319 - 64,482,534RGDNCBI36
Celera1445,467,150 - 45,467,365RGD
Cytogenetic Map14q23.3UniSTS
HuRef1445,582,190 - 45,582,405UniSTS
RH44212  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14q23.3UniSTS
GeneMap99-GB4 RH Map14153.24UniSTS
NCBI RH Map14647.8UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 982 1078 1026 381 288 248 912 488 2529 230 566 1294 144 17 370 4
Low 1449 1813 695 239 1538 214 3441 1700 1196 188 881 314 27 1187 2416
Below cutoff 3 94 2 3 116 2 3 5 4 1 5 1 1 2 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001308154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001330182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024449577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054376020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB672631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB672632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB678452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB678453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI096837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL139022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX399903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX248046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX640825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN352234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W81100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000267512   ⟹   ENSP00000267512
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,945,814 - 64,972,157 (-)Ensembl
RefSeq Acc Id: ENST00000426039   ⟹   ENSP00000433485
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,945,827 - 64,972,778 (-)Ensembl
RefSeq Acc Id: ENST00000533601   ⟹   ENSP00000434103
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,945,816 - 64,972,336 (-)Ensembl
RefSeq Acc Id: ENST00000554593   ⟹   ENSP00000452195
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,945,827 - 64,972,776 (-)Ensembl
RefSeq Acc Id: ENST00000555256
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,948,677 - 64,950,827 (-)Ensembl
RefSeq Acc Id: ENST00000585059   ⟹   ENSP00000464662
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,947,242 - 64,971,894 (-)Ensembl
RefSeq Acc Id: ENST00000642625   ⟹   ENSP00000494630
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,945,816 - 64,972,197 (-)Ensembl
RefSeq Acc Id: ENST00000642782
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,945,828 - 64,973,226 (-)Ensembl
RefSeq Acc Id: ENST00000646728   ⟹   ENSP00000496006
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,945,839 - 64,972,760 (-)Ensembl
RefSeq Acc Id: ENST00000646754   ⟹   ENSP00000494998
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1464,945,827 - 64,972,935 (-)Ensembl
RefSeq Acc Id: NM_001308154   ⟹   NP_001295083
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,945,816 - 64,972,336 (-)NCBI
CHM1_11465,350,701 - 65,377,061 (-)NCBI
T2T-CHM13v2.01459,150,685 - 59,177,205 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001330182   ⟹   NP_001317111
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,945,816 - 64,972,336 (-)NCBI
T2T-CHM13v2.01459,150,685 - 59,177,205 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198686   ⟹   NP_941959
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,945,816 - 64,972,336 (-)NCBI
GRCh371465,412,532 - 65,439,016 (-)NCBI
Build 361464,482,287 - 64,508,551 (-)NCBI Archive
Celera1445,467,116 - 45,493,459 (-)RGD
HuRef1445,582,156 - 45,608,228 (-)RGD
CHM1_11465,350,701 - 65,377,061 (-)NCBI
T2T-CHM13v2.01459,150,685 - 59,177,205 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024449577   ⟹   XP_024305345
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,945,816 - 64,957,967 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054376020   ⟹   XP_054231995
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01459,150,685 - 59,162,836 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_941959   ⟸   NM_198686
- Peptide Label: isoform 1
- UniProtKB: P59190 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001295083   ⟸   NM_001308154
- Peptide Label: isoform 2
- UniProtKB: Q86TX7 (UniProtKB/Swiss-Prot),   G5EMR7 (UniProtKB/Swiss-Prot),   Q8IW89 (UniProtKB/Swiss-Prot),   P59190 (UniProtKB/Swiss-Prot),   G5EMR8 (UniProtKB/TrEMBL),   G3V196 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001317111   ⟸   NM_001330182
- Peptide Label: isoform 3
- UniProtKB: G3V562 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024305345   ⟸   XM_024449577
- Peptide Label: isoform X1
- UniProtKB: A0A2R8Y7G7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000267512   ⟸   ENST00000267512
RefSeq Acc Id: ENSP00000433485   ⟸   ENST00000426039
RefSeq Acc Id: ENSP00000464662   ⟸   ENST00000585059
RefSeq Acc Id: ENSP00000434103   ⟸   ENST00000533601
RefSeq Acc Id: ENSP00000494630   ⟸   ENST00000642625
RefSeq Acc Id: ENSP00000494998   ⟸   ENST00000646754
RefSeq Acc Id: ENSP00000496006   ⟸   ENST00000646728
RefSeq Acc Id: ENSP00000452195   ⟸   ENST00000554593
RefSeq Acc Id: XP_054231995   ⟸   XM_054376020
- Peptide Label: isoform X1
- UniProtKB: A0A2R8Y7G7 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P59190-F1-model_v2 AlphaFold P59190 1-212 view protein structure

Promoters
RGD ID:6791829
Promoter ID:HG_KWN:19593
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid,   NB4
Transcripts:NM_198686,   UC010AQK.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361464,508,456 - 64,508,956 (-)MPROMDB
RGD ID:7227899
Promoter ID:EPDNEW_H19695
Type:initiation region
Name:RAB15_2
Description:RAB15, member RAS oncogene family
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H19696  EPDNEW_H19698  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,972,185 - 64,972,245EPDNEW
RGD ID:7227901
Promoter ID:EPDNEW_H19696
Type:initiation region
Name:RAB15_1
Description:RAB15, member RAS oncogene family
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H19695  EPDNEW_H19698  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,972,315 - 64,972,375EPDNEW
RGD ID:7227905
Promoter ID:EPDNEW_H19698
Type:initiation region
Name:RAB15_3
Description:RAB15, member RAS oncogene family
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H19695  EPDNEW_H19696  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381464,977,115 - 64,977,175EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:20150 AgrOrtholog
COSMIC RAB15 COSMIC
Ensembl Genes ENSG00000139998 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000267512 ENTREZGENE
  ENST00000267512.9 UniProtKB/Swiss-Prot
  ENST00000426039.8 UniProtKB/TrEMBL
  ENST00000533601 ENTREZGENE
  ENST00000533601.7 UniProtKB/Swiss-Prot
  ENST00000554593 ENTREZGENE
  ENST00000554593.2 UniProtKB/TrEMBL
  ENST00000585059.5 UniProtKB/TrEMBL
  ENST00000642625.1 UniProtKB/TrEMBL
  ENST00000646728 ENTREZGENE
  ENST00000646728.1 UniProtKB/TrEMBL
  ENST00000646754.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000139998 GTEx
HGNC ID HGNC:20150 ENTREZGENE
Human Proteome Map RAB15 Human Proteome Map
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rab15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:376267 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 376267 ENTREZGENE
OMIM 619547 OMIM
PANTHER LD44762P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134901572 PharmGKB
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8Y7G7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8YDI9_HUMAN UniProtKB/TrEMBL
  A0A2R8YFB8_HUMAN UniProtKB/TrEMBL
  G3V196 ENTREZGENE, UniProtKB/TrEMBL
  G3V562 ENTREZGENE, UniProtKB/TrEMBL
  G5ELZ5_HUMAN UniProtKB/TrEMBL
  G5ELZ6_HUMAN UniProtKB/TrEMBL
  G5EMR7 ENTREZGENE
  G5EMR8 ENTREZGENE, UniProtKB/TrEMBL
  J3QSF4_HUMAN UniProtKB/TrEMBL
  P59190 ENTREZGENE
  Q86TX7 ENTREZGENE
  Q8IW89 ENTREZGENE
  RAB15_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary G5EMR7 UniProtKB/Swiss-Prot
  Q86TX7 UniProtKB/Swiss-Prot
  Q8IW89 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-03-01 RAB15  RAB15, member RAS oncogene family  RAB15  RAB15, member RAS onocogene family  Symbol and/or name change 5135510 APPROVED