OR10A3 (olfactory receptor family 10 subfamily A member 3)

Gene: OR10A3 (olfactory receptor family 10 subfamily A member 3) Homo sapiens

Analyze

Symbol:

OR10A3

Name:

olfactory receptor family 10 subfamily A member 3

RGD ID:

1351222

HGNC Page

HGNC:8162

Description:

Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

HSHTPCRX12; HTPCRX12; olfactory receptor 10A3; olfactory receptor OR11-97; olfactory receptor, family 10, subfamily A, member 3

RGD Orthologs

Alliance Genes

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	7,937,171 - 7,941,708 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	7,937,171 - 7,941,708 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	7,958,718 - 7,963,255 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	7,916,699 - 7,917,643 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	7,916,698 - 7,917,643	NCBI
Celera	11	8,075,635 - 8,076,579 (-)	NCBI		Celera
Cytogenetic Map	11	p15.4	NCBI
HuRef	11	7,626,831 - 7,627,775 (-)	NCBI		HuRef
CHM1_1	11	7,959,096 - 7,960,040 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	8,016,341 - 8,020,876 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

acrylamide (ISO)

aflatoxin B1 (EXP)

benzo[a]pyrene (EXP)

bisphenol A (ISO)

CGP 52608 (EXP)

crocidolite asbestos (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of smell (IBA,IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of smell (IEA,NAS)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

olfactory receptor activity (IBA,IEA,NAS)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:1370859	PMID:12213199	PMID:12477932	PMID:14983052	PMID:16554811	PMID:21873635	PMID:23042114	PMID:36552724

Genomics

Comparative Map Data

OR10A3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	7,937,171 - 7,941,708 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	7,937,171 - 7,941,708 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	7,958,718 - 7,963,255 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	7,916,699 - 7,917,643 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	7,916,698 - 7,917,643	NCBI
Celera	11	8,075,635 - 8,076,579 (-)	NCBI		Celera
Cytogenetic Map	11	p15.4	NCBI
HuRef	11	7,626,831 - 7,627,775 (-)	NCBI		HuRef
CHM1_1	11	7,959,096 - 7,960,040 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	8,016,341 - 8,020,876 (-)	NCBI		T2T-CHM13v2.0

Or10a3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	108,479,810 - 108,480,811 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	108,479,395 - 108,484,213 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	108,880,603 - 108,881,604 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	108,880,188 - 108,885,006 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	116,024,117 - 116,025,118 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	108,671,780 - 108,672,781 (-)	NCBI		MGSCv36	mm8
Celera	7	108,857,157 - 108,858,158 (-)	NCBI		Celera
Cytogenetic Map	7	E3	NCBI
cM Map	7	57.21	NCBI

Or10a3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	172,291,739 - 172,292,719 (-)	NCBI		GRCr8
mRatBN7.2	1	162,856,896 - 162,857,876 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	162,856,896 - 162,857,897 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	171,191,625 - 171,192,605 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	178,377,636 - 178,378,616 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	171,056,351 - 171,057,330 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	173,455,508 - 173,456,488 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	173,455,508 - 173,456,488 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	180,444,624 - 180,445,604 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	166,484,739 - 166,485,719 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	166,595,401 - 166,596,382 (+)	NCBI
Celera	1	160,763,537 - 160,764,517 (-)	NCBI		Celera
Cytogenetic Map	1	q33	NCBI

LOC102013596
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	23,775,674 - 23,776,618 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	23,775,674 - 23,776,654 (-)	NCBI	ChiLan1.0	ChiLan1.0

OR10A3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	31,492,259 - 31,493,203 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	31,492,259 - 31,493,203 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	31,061,514 - 31,062,458 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	32,366,190 - 32,367,134 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	32,366,190 - 32,367,134 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	31,636,019 - 31,636,963 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	31,802,161 - 31,803,105 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	32,095,906 - 32,096,850 (-)	NCBI		UU_Cfam_GSD_1.0

OR10A3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	1,324,378 - 1,366,814 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	1,323,258 - 1,325,761 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	1,628,949 - 1,630,150 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103240935
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	56,856,155 - 56,857,610 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	154,585,799 - 154,586,992 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101701979
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624766	159,944 - 160,891 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in OR10A3
17 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 11p15.5-13(chr11:202758-31726224)x3	copy number gain	See cases [RCV000053613]	Chr11:202758..31726224 [GRCh38] Chr11:202758..31747772 [GRCh37] Chr11:192758..31704348 [NCBI36] Chr11:11p15.5-13	pathogenic
NM_001003745.1(OR10A3):c.435A>G (p.Val145=)	single nucleotide variant	Malignant melanoma [RCV000069716]	Chr11:7939086 [GRCh38] Chr11:7960633 [GRCh37] Chr11:7917209 [NCBI36] Chr11:11p15.4	not provided
GRCh38/hg38 11p15.5-15.1(chr11:446754-18904742)x3	copy number gain	See cases [RCV000133997]	Chr11:446754..18904742 [GRCh38] Chr11:446754..18926289 [GRCh37] Chr11:436754..18882865 [NCBI36] Chr11:11p15.5-15.1	pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:61793-10727969)x3	copy number gain	See cases [RCV000139987]	Chr11:61793..10727969 [GRCh38] Chr11:61793..10749516 [GRCh37] Chr11:51793..10706092 [NCBI36] Chr11:11p15.5-15.4	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)	copy number gain	See cases [RCV000511729]	Chr11:230616..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11p15.5-12(chr11:230615-37698540)x3	copy number gain	See cases [RCV000511561]	Chr11:230615..37698540 [GRCh37] Chr11:11p15.5-12	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3	copy number gain	See cases [RCV000510881]	Chr11:230616..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11p15.5-15.3(chr11:193146-12643136)	copy number gain	Silver-Russell syndrome 1 [RCV000767567]	Chr11:193146..12643136 [GRCh37] Chr11:11p15.5-15.3	pathogenic
NM_001003745.2(OR10A3):c.397C>T (p.Pro133Ser)	single nucleotide variant	Inborn genetic diseases [RCV003288659]	Chr11:7939124 [GRCh38] Chr11:7960671 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.5-14.3(chr11:230615-25584362)x3	copy number gain	See cases [RCV000512225]	Chr11:230615..25584362 [GRCh37] Chr11:11p15.5-14.3	pathogenic
GRCh37/hg19 11p15.5-13(chr11:230615-31995219)x3	copy number gain	See cases [RCV000512477]	Chr11:230615..31995219 [GRCh37] Chr11:11p15.5-13	pathogenic
GRCh37/hg19 11p15.4(chr11:7837338-9295428)x3	copy number gain	not provided [RCV000683357]	Chr11:7837338..9295428 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.4(chr11:6969013-9257231)x3	copy number gain	not provided [RCV000683360]	Chr11:6969013..9257231 [GRCh37] Chr11:11p15.4	pathogenic
GRCh37/hg19 11p15.4(chr11:7418934-8308834)x3	copy number gain	not provided [RCV000683352]	Chr11:7418934..8308834 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:230615-9704511)x3	copy number gain	not provided [RCV000683369]	Chr11:230615..9704511 [GRCh37] Chr11:11p15.5-15.4	pathogenic
GRCh37/hg19 11p15.4(chr11:7797256-7982842)x1	copy number loss	not provided [RCV000683314]	Chr11:7797256..7982842 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.5-15.1(chr11:230615-17099213)x3	copy number gain	not provided [RCV000683372]	Chr11:230615..17099213 [GRCh37] Chr11:11p15.5-15.1	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3	copy number gain	not provided [RCV000737348]	Chr11:198510..134934063 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3	copy number gain	not provided [RCV000749874]	Chr11:70864..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
NM_001003745.2(OR10A3):c.73G>A (p.Val25Met)	single nucleotide variant	Inborn genetic diseases [RCV003247530]	Chr11:7939448 [GRCh38] Chr11:7960995 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.4(chr11:7953436-8303138)x3	copy number gain	not provided [RCV000846250]	Chr11:7953436..8303138 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.5-13(chr11:235934-33826995)x3	copy number gain	not provided [RCV001006372]	Chr11:235934..33826995 [GRCh37] Chr11:11p15.5-13	pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:210300-8664358)x3	copy number gain	Silver-Russell syndrome 1 [RCV001263222]	Chr11:210300..8664358 [GRCh37] Chr11:11p15.5-15.4	pathogenic
GRCh37/hg19 11p15.5-14.2(chr11:230615-26881146)x3	copy number gain	See cases [RCV002286351]	Chr11:230615..26881146 [GRCh37] Chr11:11p15.5-14.2	pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230616-8250724)x3	copy number gain	not provided [RCV002472435]	Chr11:230616..8250724 [GRCh37] Chr11:11p15.5-15.4	pathogenic
NM_001003745.2(OR10A3):c.350C>T (p.Ala117Val)	single nucleotide variant	Inborn genetic diseases [RCV002951131]	Chr11:7939171 [GRCh38] Chr11:7960718 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.653A>G (p.Tyr218Cys)	single nucleotide variant	Inborn genetic diseases [RCV002844300]	Chr11:7938868 [GRCh38] Chr11:7960415 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.871A>G (p.Ser291Gly)	single nucleotide variant	Inborn genetic diseases [RCV002954810]	Chr11:7938650 [GRCh38] Chr11:7960197 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.585T>A (p.Phe195Leu)	single nucleotide variant	Inborn genetic diseases [RCV002742270]	Chr11:7938936 [GRCh38] Chr11:7960483 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.622A>G (p.Met208Val)	single nucleotide variant	Inborn genetic diseases [RCV002789434]	Chr11:7938899 [GRCh38] Chr11:7960446 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.73G>T (p.Val25Leu)	single nucleotide variant	Inborn genetic diseases [RCV002916625]	Chr11:7939448 [GRCh38] Chr11:7960995 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.772A>T (p.Thr258Ser)	single nucleotide variant	Inborn genetic diseases [RCV002742543]	Chr11:7938749 [GRCh38] Chr11:7960296 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.365G>A (p.Arg122Gln)	single nucleotide variant	Inborn genetic diseases [RCV002940839]	Chr11:7939156 [GRCh38] Chr11:7960703 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.659G>A (p.Arg220Gln)	single nucleotide variant	Inborn genetic diseases [RCV002669766]	Chr11:7938862 [GRCh38] Chr11:7960409 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.878G>A (p.Arg293Gln)	single nucleotide variant	Inborn genetic diseases [RCV002703397]	Chr11:7938643 [GRCh38] Chr11:7960190 [GRCh37] Chr11:11p15.4	likely benign
NM_001003745.2(OR10A3):c.883A>G (p.Ser295Gly)	single nucleotide variant	Inborn genetic diseases [RCV002920459]	Chr11:7938638 [GRCh38] Chr11:7960185 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.775T>C (p.Tyr259His)	single nucleotide variant	Inborn genetic diseases [RCV003213100]	Chr11:7938746 [GRCh38] Chr11:7960293 [GRCh37] Chr11:11p15.4	uncertain significance
NM_001003745.2(OR10A3):c.486G>T (p.Trp162Cys)	single nucleotide variant	Inborn genetic diseases [RCV003367191]	Chr11:7939035 [GRCh38] Chr11:7960582 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.4(chr11:7922549-8155364)x3	copy number gain	not provided [RCV003484832]	Chr11:7922549..8155364 [GRCh37] Chr11:11p15.4	uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:230615-8821443)x3	copy number gain	Russell-Silver syndrome [RCV003444025]	Chr11:230615..8821443 [GRCh37] Chr11:11p15.5-15.4	pathogenic

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	108
Count of miRNA genes:	101
Interacting mature miRNAs:	104
Transcripts:	ENST00000360759
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	adipose tissue	appendage	entire extraembryonic component
High
Medium
Low	6	4	2	1	2	1	287	2	5	7	28	12	2		166
Below cutoff	230	339	59	79	65	19	1182	77	171	77	451	211	64	63	601	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001003745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB065768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB065940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC044810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF399634	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284332	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284333	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284337	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY284356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137032	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BK004404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KP290445	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X64986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000360759 ⟹ ENSP00000353988

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	11	7,938,534 - 7,939,594 (-)	Ensembl

RefSeq Acc Id:

ENST00000642047 ⟹ ENSP00000493303

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	11	7,937,171 - 7,941,708 (-)	Ensembl

RefSeq Acc Id:

NM_001003745 ⟹ NP_001003745

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	11	7,937,171 - 7,941,708 (-)	NCBI
GRCh37	11	7,960,123 - 7,961,067 (-)	RGD
Build 36	11	7,916,699 - 7,917,643 (-)	NCBI Archive
Celera	11	8,075,635 - 8,076,579 (-)	RGD
HuRef	11	7,626,831 - 7,627,775 (-)	RGD
CHM1_1	11	7,959,096 - 7,960,040 (-)	NCBI
T2T-CHM13v2.0	11	8,016,341 - 8,020,876 (-)	NCBI

Sequence:

show sequence

CAGGGACAGTGAATAGATAAGGATCTGAAGATTCTGCTTTGGTACTTGTTGGTGGGTTTGCCTT
CTGTAGTTATCCTCACTGATAATTGGAGATACTTATCAAGTGATAACTCAATGCTCAGATTCAC
TATTACAAGTCATTGGCCATTCTTCAAAAGTGCCAACCTGAAGTTCTGTCAAAATGAGCTTGTC
ATTACATCTGCTGTCAAGAATTCCAGACTTGAACTCACAGCTATGGGATTACGACTTCATACTC
GATATACCAGGTCCATAAAAACAATATAAGTTTCAACTACTGAAATGAAAAGACAAAATCAAAG
CTGTGTGGTTGAATTCATCCTCCTGGGCTTTTCTAACTTTCCTGAGCTCCAGGTGCAGCTCTTT
GGGGTTTTCCTAGTTATTTATGTGGTGACCCTGATGGGAAATGCCATCATTACAGTCATCATCT
CCTTAAACCAGAGCCTCCACGTTCCCATGTACCTGTTCCTCCTGAACCTATCTGTGGTGGAGGT
GAGTTTCAGTGCAGTCATTACGCCTGAAATGCTGGTGGTGCTCTCTACTGAGAAAACTATGATT
TCTTTTGTGGGCTGTTTTGCACAGATGTATTTCATCCTTCTTTTTGGTGGGACTGAATGTTTTC
TCCTGGGAGCGATGGCTTATGACCGATTTGCTGCAATTTGCCATCCTCTGAACTACCCAGTGAT
TATGAACAGAGGGGTTTTTATGAAATTAGTAATATTCTCATGGATCTCAGGGATCATGGTGGCT
ACTGTGCAGACCACTTGGGTATTTAGTTTTCCATTTTGTGGCCCCAATGAAATTAATCATCTCT
TCTGTGAGACTCCCCCGGTACTAGAGCTTGTGTGTGCAGACACCTTCTTATTTGAAATCTATGC
CTTCACAGGCACCATTTTGATTGTTATGGTTCCTTTCTTGTTGATCCTCTTGTCTTACATTCGA
GTTCTGTTTGCCATCCTGAAGATGCCATCAACTACTGGGAGACAAAAGGCCTTTTCCACCTGTG
CCTCTCACCTCACATCTGTGACCCTGTTCTATGGCACAGCCAATATGACTTATTTACAACCCAA
ATCTGGCTACTCACCCGAAACCAAGAAACTGATCTCATTGGCTTACACGTTGCTTACCCCTCTG
CTCAATCCGCTCATCTATAGCTTACGAAACAGTGAGATGAAGAGGACTTTGATAAAACTATGGC
GAAGAAAAGTGATTTTACACACATTCTGATTGTGTTGAGAAGCTGAGTAAGATTTGGCCACTGC
CTGAGTGAACTCTATTTAAATTTAATAAAGGGTGAAAACAGACTGCATTTTTTGTATGACTATG
TAAGTTTGTTGAGTTTTTTTATTGGAAAACGTATCTCAATAAAGAACTGCTGTCACTTGTTTTT
AGTAGATACATATGTTCTCATAACATGACACAACAGTTTATTCATCCATTTCTCTATTATGAAC
ATCCAAGTAGCTACTGGATTACTGTCATTTTTTTTTTTTTTTTTTTTGAGATGGAGTTTCGCTC
CAGCCCAGGCTGGAGTGCAATGGCACGATCTGGGCTCACTGCAACCTCCACCTCCTGGGTTCTA
GCAATTCTCCTGCCTCAGCCTCCCGAGTAGTTGGGATTACAGGCATGCGCCACCACACCCAGCT
AATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGCTGGTCAGGCTGGTCTCAAACTCCCA
ACCTTAGATGATCCGCCCACCTCGGCCTCCCAAAGCGCTGTGATTACAGGTGTGAGCCACCACG
CCTGGCCTGGATTACTGTCATTAAGACAGTGCTTCAATAAATGCCTTGTTCCATATGCTCATAT
GTACTGATGTCATTATACCTGTGTGATAGATTTGCTACAGTGCGGCTGATAGGATGAGGAGTAT
CTGTGTTTACAAATTTTATTAGCTATTGCAGAATTACTTTTCAAAATGATTATAGTTCTTCAGA
CTGGCCTGAAGGCTCACTGTGCTTTGGTAACAGGGTAGAGCTTCAAGAGACCAACAAATAAGGT
GATGATGTTTCTATTTTTGGATTGAAAATTTGTTCCACGGATGAGTAAAAAAAAAGTGCATCTA
TTTTGGGGGGCCAAAAATGGTTCTACTTCATGACCTTACACAAATTATAATCCCAAACTGGATT
TCTCTTGGTATCTTTCCAAATATTTATCCAATGTTGGTGACCAGAGAGCTACATGGGAAGTTTC
TCAAATTCTCATTTGATAATATCAGTATCTTTTTCATTTACAGACCACTGATTTAGAAACTTTT
ATGAAGTTTCCTTTTGTAGTCTGTGACAGGAAAGTAAAATCTTGGAACCCCAAACTCACTATGC
CAAAAGAAAAGTTAAGCTTGGAAACTGGCTCAGGCAAAAAAATTGCCTTTCCTTTTGTTCCTAA
ATAGATAGCTACAAGATATCCGGTCACCTATCTTCCCAGGTTACCTCCCTCAATTGTTCTTAAA
AATAATTGGAATAAAACTGATACTGTGATGTTAAGATTAGATATACATATTCTGCTAAATGAAG
GGGTGTCATTATAATTTGTGTATATTATTTGGGAATAGGCAATACATATATATATCTGTGTGTC
TATTTAAACTGGTTTTAGGTTTATAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001003745	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI37032	(Get FASTA)	NCBI Sequence Viewer
	AAI37033	(Get FASTA)	NCBI Sequence Viewer
	AAK95119	(Get FASTA)	NCBI Sequence Viewer
	ALI87612	(Get FASTA)	NCBI Sequence Viewer
	BAC05988	(Get FASTA)	NCBI Sequence Viewer
	BAC06155	(Get FASTA)	NCBI Sequence Viewer
	DAA04802	(Get FASTA)	NCBI Sequence Viewer
	EAW68641	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000484096.1
	ENSP00000487530.1
	ENSP00000493029.1
	ENSP00000493303
	ENSP00000493303.1
GenBank Protein	P58181	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001003745 ⟸ NM_001003745

- UniProtKB:

Q6IF58 (UniProtKB/Swiss-Prot), B9EH39 (UniProtKB/Swiss-Prot), Q96R11 (UniProtKB/Swiss-Prot), P58181 (UniProtKB/Swiss-Prot), A0A126GVZ2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKRQNQSCVVEFILLGFSNFPELQVQLFGVFLVIYVVTLMGNAIITVIISLNQSLHVPMYLFLL
NLSVVEVSFSAVITPEMLVVLSTEKTMISFVGCFAQMYFILLFGGTECFLLGAMAYDRFAAICH
PLNYPVIMNRGVFMKLVIFSWISGIMVATVQTTWVFSFPFCGPNEINHLFCETPPVLELVCADT
FLFEIYAFTGTILIVMVPFLLILLSYIRVLFAILKMPSTTGRQKAFSTCASHLTSVTLFYGTAN
MTYLQPKSGYSPETKKLISLAYTLLTPLLNPLIYSLRNSEMKRTLIKLWRRKVILHTF

hide sequence

RefSeq Acc Id:

ENSP00000353988 ⟸ ENST00000360759

RefSeq Acc Id:

ENSP00000493303 ⟸ ENST00000642047

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P58181-F1-model_v2	AlphaFold	P58181	1-314	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:8162	AgrOrtholog
COSMIC	OR10A3	COSMIC
Ensembl Genes	ENSG00000170683	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSG00000273953	UniProtKB/Swiss-Prot
	ENSG00000281680	UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000612788.1	UniProtKB/Swiss-Prot
	ENST00000626843.1	UniProtKB/Swiss-Prot
	ENST00000641438.1	UniProtKB/Swiss-Prot
	ENST00000642047	ENTREZGENE
	ENST00000642047.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000170683	GTEx
	ENSG00000273953	GTEx
	ENSG00000281680	GTEx
HGNC ID	HGNC:8162	ENTREZGENE
Human Proteome Map	OR10A3	Human Proteome Map
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:26496	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	26496	ENTREZGENE
PANTHER	OLFACTORY RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORY RECEPTOR 10A3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA31951	PharmGKB
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A126GVZ2	ENTREZGENE, UniProtKB/TrEMBL
	B9EH39	ENTREZGENE
	O10A3_HUMAN	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6IF58	ENTREZGENE
	Q96R11	ENTREZGENE
UniProt Secondary	B9EH39	UniProtKB/Swiss-Prot
	Q6IF58	UniProtKB/Swiss-Prot
	Q96R11	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-15	OR10A3	olfactory receptor family 10 subfamily A member 3	OR10A3	olfactory receptor, family 10, subfamily A, member 3	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar