COMMD10 (COMM domain containing 10) - Rat Genome Database

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Gene: COMMD10 (COMM domain containing 10) Homo sapiens
Analyze
Symbol: COMMD10
Name: COMM domain containing 10
RGD ID: 1346630
HGNC Page HGNC:30201
Description: Located in nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: COMM domain-containing protein 10; FLJ11285; PTD002
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385116,085,025 - 116,293,287 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5116,085,016 - 116,412,762 (+)EnsemblGRCh38hg38GRCh38
GRCh375115,420,722 - 115,628,984 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,448,626 - 115,656,880 (+)NCBINCBI36Build 36hg18NCBI36
Build 345115,448,625 - 115,656,877NCBI
Celera5111,369,127 - 111,578,514 (+)NCBICelera
Cytogenetic Map5q23.1NCBI
HuRef5110,601,462 - 110,809,519 (+)NCBIHuRef
CHM1_15114,853,501 - 115,061,550 (+)NCBICHM1_1
T2T-CHM13v2.05116,597,411 - 116,805,723 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleoplasm  (IDA)
nucleus  (IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Autism  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11042152   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15799966   PMID:16344560   PMID:17207965   PMID:19913121   PMID:20628086   PMID:21778237   PMID:22228203   PMID:22688191  
PMID:22939629   PMID:23563313   PMID:23934736   PMID:24993907   PMID:25355947   PMID:26186194   PMID:26344197   PMID:26496610   PMID:28514442   PMID:28817833   PMID:29997525   PMID:30787448  
PMID:30833792   PMID:31540324   PMID:32296183   PMID:32393512   PMID:32687490   PMID:32814053   PMID:33060197   PMID:33961781   PMID:34047468   PMID:35101526   PMID:35235311   PMID:35271311  
PMID:36919165   PMID:37172566  


Genomics

Comparative Map Data
COMMD10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385116,085,025 - 116,293,287 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5116,085,016 - 116,412,762 (+)EnsemblGRCh38hg38GRCh38
GRCh375115,420,722 - 115,628,984 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,448,626 - 115,656,880 (+)NCBINCBI36Build 36hg18NCBI36
Build 345115,448,625 - 115,656,877NCBI
Celera5111,369,127 - 111,578,514 (+)NCBICelera
Cytogenetic Map5q23.1NCBI
HuRef5110,601,462 - 110,809,519 (+)NCBIHuRef
CHM1_15114,853,501 - 115,061,550 (+)NCBICHM1_1
T2T-CHM13v2.05116,597,411 - 116,805,723 (+)NCBIT2T-CHM13v2.0
Commd10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391847,091,917 - 47,242,435 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1847,091,883 - 47,367,351 (+)EnsemblGRCm39 Ensembl
GRCm381846,958,819 - 47,087,995 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1846,958,816 - 47,234,284 (+)EnsemblGRCm38mm10GRCm38
MGSCv371847,118,530 - 47,247,649 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361847,084,207 - 47,213,326 (+)NCBIMGSCv36mm8
Celera1848,320,570 - 48,450,579 (+)NCBICelera
Cytogenetic Map18CNCBI
cM Map1824.9NCBI
Commd10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81841,927,802 - 42,061,384 (+)NCBIGRCr8
mRatBN7.21839,741,219 - 39,874,801 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1839,741,298 - 39,874,903 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1841,774,508 - 41,907,990 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01842,476,755 - 42,610,256 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01840,269,855 - 40,403,350 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01841,022,487 - 41,158,374 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1841,022,552 - 41,154,932 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01840,666,615 - 40,798,878 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41841,226,869 - 41,362,841 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11841,264,409 - 41,400,381 (+)NCBI
Celera1837,992,809 - 38,125,779 (+)NCBICelera
Cytogenetic Map18q11NCBI
Commd10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540835,887,802 - 36,043,835 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540835,887,995 - 36,045,085 (+)NCBIChiLan1.0ChiLan1.0
COMMD10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24111,330,035 - 111,533,397 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15109,482,867 - 109,687,058 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05111,439,100 - 111,642,742 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15117,236,606 - 117,438,866 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5117,236,804 - 117,438,068 (+)Ensemblpanpan1.1panPan2
COMMD10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1115,800,880 - 5,985,775 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl115,800,928 - 5,984,924 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha115,951,513 - 6,136,406 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0115,792,736 - 5,977,761 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl115,792,791 - 5,979,955 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1115,741,476 - 5,926,343 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0115,819,121 - 6,004,160 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0116,070,827 - 6,255,975 (+)NCBIUU_Cfam_GSD_1.0
Commd10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213128,566,476 - 128,770,756 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367421,267,282 - 1,475,072 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367421,267,334 - 1,471,521 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COMMD10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2120,238,614 - 120,445,021 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12120,238,543 - 120,444,409 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22125,144,480 - 125,375,337 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COMMD10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12319,373,892 - 19,601,508 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2319,373,864 - 19,448,138 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603458,803,263 - 59,033,962 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Commd10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247335,561,391 - 5,751,334 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247335,563,258 - 5,751,340 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in COMMD10
12 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NC_000005.9:g.(?_86400000)_(154000000_?)del deletion Familial adenomatous polyposis 1 [RCV002231249]|Hereditary cancer-predisposing syndrome [RCV000554476] Chr5:86400000..154000000 [GRCh37]
Chr5:5q14.3-33.2		 pathogenic
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1 copy number loss See cases [RCV000053524] Chr5:106619588..156124387 [GRCh38]
Chr5:105955289..155551397 [GRCh37]
Chr5:105983188..155483975 [NCBI36]
Chr5:5q21.3-33.2		 pathogenic
GRCh38/hg38 5q21.3-23.1(chr5:108585264-116815075)x1 copy number loss See cases [RCV000133813] Chr5:108585264..116815075 [GRCh38]
Chr5:107920965..116150771 [GRCh37]
Chr5:107948864..116178670 [NCBI36]
Chr5:5q21.3-23.1		 pathogenic
GRCh38/hg38 5q22.3-23.2(chr5:114707561-126507744)x1 copy number loss See cases [RCV000134895] Chr5:114707561..126507744 [GRCh38]
Chr5:114043258..125843436 [GRCh37]
Chr5:114071157..125871335 [NCBI36]
Chr5:5q22.3-23.2		 pathogenic
GRCh38/hg38 5q21.3-23.1(chr5:107002209-118025316)x1 copy number loss See cases [RCV000135699] Chr5:107002209..118025316 [GRCh38]
Chr5:106337910..117361011 [GRCh37]
Chr5:106365809..117388910 [NCBI36]
Chr5:5q21.3-23.1		 pathogenic
GRCh38/hg38 5q22.1-23.2(chr5:111463016-127193038)x1 copy number loss See cases [RCV000135549] Chr5:111463016..127193038 [GRCh38]
Chr5:110798714..126528730 [GRCh37]
Chr5:110826613..126556629 [NCBI36]
Chr5:5q22.1-23.2		 pathogenic
GRCh38/hg38 5q22.1-23.3(chr5:110687442-130103838)x1 copy number loss See cases [RCV000139235] Chr5:110687442..130103838 [GRCh38]
Chr5:110023143..129439531 [GRCh37]
Chr5:110051042..129467430 [NCBI36]
Chr5:5q22.1-23.3		 pathogenic|uncertain significance
GRCh38/hg38 5q14.3-23.3(chr5:90374606-128076423)x1 copy number loss See cases [RCV000139893] Chr5:90374606..128076423 [GRCh38]
Chr5:89670423..127412115 [GRCh37]
Chr5:89706179..127440014 [NCBI36]
Chr5:5q14.3-23.3		 pathogenic
GRCh38/hg38 5q14.3-23.1(chr5:92899734-119614119)x1 copy number loss See cases [RCV000141252] Chr5:92899734..119614119 [GRCh38]
Chr5:92235441..118949814 [GRCh37]
Chr5:92261197..118977713 [NCBI36]
Chr5:5q14.3-23.1		 pathogenic
GRCh38/hg38 5q22.2-23.1(chr5:112323517-117773507)x1 copy number loss See cases [RCV000140791] Chr5:112323517..117773507 [GRCh38]
Chr5:111659214..117109202 [GRCh37]
Chr5:111687113..117137101 [NCBI36]
Chr5:5q22.2-23.1		 pathogenic
GRCh38/hg38 5q23.1(chr5:116172632-116197770)x3 copy number gain See cases [RCV000140960] Chr5:116172632..116197770 [GRCh38]
Chr5:115508329..115533467 [GRCh37]
Chr5:115536228..115561366 [NCBI36]
Chr5:5q23.1		 benign
GRCh38/hg38 5q23.1(chr5:116197770-116249556)x1 copy number loss See cases [RCV000140961] Chr5:116197770..116249556 [GRCh38]
Chr5:115533467..115585253 [GRCh37]
Chr5:115561366..115613152 [NCBI36]
Chr5:5q23.1		 benign
GRCh38/hg38 5q21.3-23.2(chr5:108308463-125777797)x1 copy number loss See cases [RCV000143326] Chr5:108308463..125777797 [GRCh38]
Chr5:107644164..125113490 [GRCh37]
Chr5:107672063..125141389 [NCBI36]
Chr5:5q21.3-23.2		 pathogenic
GRCh38/hg38 5q14.3-31.1(chr5:91411708-131319563)x1 copy number loss See cases [RCV000143746] Chr5:91411708..131319563 [GRCh38]
Chr5:90707525..130655256 [GRCh37]
Chr5:90743281..130683155 [NCBI36]
Chr5:5q14.3-31.1		 pathogenic
NR_104675.1(LOC101927190):n.1544C>T single nucleotide variant Lung cancer [RCV000095223] Chr5:116369130 [GRCh38]
Chr5:115704827 [GRCh37]
Chr5:5q23.1		 uncertain significance
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3		 likely benign
GRCh37/hg19 5q22.1-23.2(chr5:110407606-122522885)x1 copy number loss See cases [RCV000446959] Chr5:110407606..122522885 [GRCh37]
Chr5:5q22.1-23.2		 pathogenic
GRCh37/hg19 5q21.1-23.2(chr5:100607918-125900735)x1 copy number loss See cases [RCV000445968] Chr5:100607918..125900735 [GRCh37]
Chr5:5q21.1-23.2		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3		 pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
Single allele duplication Autism [RCV000754292] Chr5:114046360..118610426 [GRCh38]
Chr5:5q22.3-23.1		 likely pathogenic
GRCh37/hg19 5q23.1(chr5:115229725-115450657)x3 copy number gain not provided [RCV000745101] Chr5:115229725..115450657 [GRCh37]
Chr5:5q23.1		 benign
GRCh37/hg19 5q23.1(chr5:115236690-115453671)x3 copy number gain not provided [RCV000745102] Chr5:115236690..115453671 [GRCh37]
Chr5:5q23.1		 benign
GRCh37/hg19 5q23.1(chr5:115322822-115517399)x3 copy number gain not provided [RCV000745103] Chr5:115322822..115517399 [GRCh37]
Chr5:5q23.1		 benign
GRCh37/hg19 5q23.1(chr5:115540041-115609347)x1 copy number loss not provided [RCV000745104] Chr5:115540041..115609347 [GRCh37]
Chr5:5q23.1		 benign
GRCh37/hg19 5q23.1(chr5:115540041-115627570)x1 copy number loss not provided [RCV000745105] Chr5:115540041..115627570 [GRCh37]
Chr5:5q23.1		 benign
GRCh37/hg19 5q23.1(chr5:115553944-115601291)x1 copy number loss not provided [RCV000745106] Chr5:115553944..115601291 [GRCh37]
Chr5:5q23.1		 benign
GRCh37/hg19 5q23.1(chr5:115568712-115713688)x1 copy number loss not provided [RCV000745107] Chr5:115568712..115713688 [GRCh37]
Chr5:5q23.1		 benign
GRCh37/hg19 5q14.3-23.3(chr5:89949118-129317455)x3 copy number gain not provided [RCV000849289] Chr5:89949118..129317455 [GRCh37]
Chr5:5q14.3-23.3		 pathogenic
GRCh37/hg19 5q21.3-23.1(chr5:108304806-121335239)x1 copy number loss not provided [RCV000846246] Chr5:108304806..121335239 [GRCh37]
Chr5:5q21.3-23.1		 pathogenic
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32		 uncertain significance
GRCh37/hg19 5q23.1(chr5:115472743-116126058)x3 copy number gain not provided [RCV001005721] Chr5:115472743..116126058 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_016144.4(COMMD10):c.373C>T (p.Arg125Trp) single nucleotide variant not specified [RCV004288892] Chr5:116092674 [GRCh38]
Chr5:115428371 [GRCh37]
Chr5:5q23.1		 uncertain significance
GRCh37/hg19 5q22.1-23.1(chr5:111443783-116255660) copy number loss not specified [RCV002053518] Chr5:111443783..116255660 [GRCh37]
Chr5:5q22.1-23.1		 pathogenic
GRCh37/hg19 5q21.1-23.2(chr5:100607918-125900735) copy number loss not specified [RCV002053515] Chr5:100607918..125900735 [GRCh37]
Chr5:5q21.1-23.2		 pathogenic
GRCh37/hg19 5q22.2-23.3(chr5:112557391-128106299)x1 copy number loss not provided [RCV002475732] Chr5:112557391..128106299 [GRCh37]
Chr5:5q22.2-23.3		 pathogenic
NM_016144.4(COMMD10):c.176C>T (p.Ala59Val) single nucleotide variant not specified [RCV004216416] Chr5:116091122 [GRCh38]
Chr5:115426819 [GRCh37]
Chr5:5q23.1		 likely benign
NM_016144.4(COMMD10):c.76G>C (p.Asp26His) single nucleotide variant not specified [RCV004233268] Chr5:116087531 [GRCh38]
Chr5:115423228 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_016144.4(COMMD10):c.106C>T (p.Arg36Trp) single nucleotide variant not specified [RCV004216869] Chr5:116087561 [GRCh38]
Chr5:115423258 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_016144.4(COMMD10):c.10C>T (p.Pro4Ser) single nucleotide variant not specified [RCV004187012] Chr5:116085062 [GRCh38]
Chr5:115420759 [GRCh37]
Chr5:5q23.1		 likely benign
NM_016144.4(COMMD10):c.556G>T (p.Asp186Tyr) single nucleotide variant not specified [RCV004274720] Chr5:116291562 [GRCh38]
Chr5:115627259 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_016144.4(COMMD10):c.498T>A (p.Asn166Lys) single nucleotide variant not specified [RCV004277451] Chr5:116134166 [GRCh38]
Chr5:115469863 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_016144.4(COMMD10):c.44T>C (p.Met15Thr) single nucleotide variant not specified [RCV004261815] Chr5:116087499 [GRCh38]
Chr5:115423196 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_016144.4(COMMD10):c.562T>C (p.Tyr188His) single nucleotide variant not specified [RCV004251360] Chr5:116291568 [GRCh38]
Chr5:115627265 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_016144.4(COMMD10):c.575A>G (p.Glu192Gly) single nucleotide variant not specified [RCV004437741] Chr5:116292455 [GRCh38]
Chr5:115628152 [GRCh37]
Chr5:5q23.1		 uncertain significance
GRCh37/hg19 5q15-23.2(chr5:93828571-123711334)x1 copy number loss not specified [RCV003986577] Chr5:93828571..123711334 [GRCh37]
Chr5:5q15-23.2		 pathogenic
GRCh37/hg19 5q23.1(chr5:115387163-115469875)x1 copy number loss not provided [RCV003885512] Chr5:115387163..115469875 [GRCh37]
Chr5:5q23.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:885
Count of miRNA genes:502
Interacting mature miRNAs:535
Transcripts:ENST00000274458, ENST00000503424, ENST00000506589, ENST00000507356, ENST00000508250, ENST00000515539
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-30887  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,575,745 - 115,575,845UniSTSGRCh37
Build 365115,603,644 - 115,603,744RGDNCBI36
Celera5111,525,278 - 111,525,378RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,756,610 - 110,756,710UniSTS
Stanford-G3 RH Map54496.0UniSTS
GeneMap99-GB4 RH Map5474.81UniSTS
Whitehead-RH Map5382.9UniSTS
NCBI RH Map5826.1UniSTS
GeneMap99-G3 RH Map54584.0UniSTS
RH104116  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,565,996 - 115,566,076UniSTSGRCh37
Build 365115,593,895 - 115,593,975RGDNCBI36
Celera5111,515,529 - 111,515,609RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,746,861 - 110,746,941UniSTS
GeneMap99-GB4 RH Map5476.34UniSTS
SHGC-78602  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,508,559 - 115,508,860UniSTSGRCh37
Build 365115,536,458 - 115,536,759RGDNCBI36
Celera5111,458,063 - 111,458,364RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,689,324 - 110,689,625UniSTS
TNG Radiation Hybrid Map552911.0UniSTS
SHGC-81710  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,450,913 - 115,451,249UniSTSGRCh37
Build 365115,478,812 - 115,479,148RGDNCBI36
Celera5111,399,342 - 111,399,678RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,631,708 - 110,632,044UniSTS
TNG Radiation Hybrid Map553151.0UniSTS
RH121423  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,627,533 - 115,627,827UniSTSGRCh37
Build 365115,655,432 - 115,655,726RGDNCBI36
Celera5111,577,069 - 111,577,363RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,808,074 - 110,808,368UniSTS
TNG Radiation Hybrid Map553199.0UniSTS
RH122602  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,472,531 - 115,472,813UniSTSGRCh37
Build 365115,500,430 - 115,500,712RGDNCBI36
Celera5111,420,728 - 111,421,010RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,653,087 - 110,653,369UniSTS
TNG Radiation Hybrid Map553001.0UniSTS
SHGC-142273  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,570,812 - 115,571,142UniSTSGRCh37
Build 365115,598,711 - 115,599,041RGDNCBI36
Celera5111,520,345 - 111,520,675RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,751,677 - 110,752,007UniSTS
bac53028T  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,545,221 - 115,545,441UniSTSGRCh37
Build 365115,573,120 - 115,573,340RGDNCBI36
Celera5111,494,725 - 111,494,945RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,725,984 - 110,726,204UniSTS
G65578  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,574,589 - 115,574,939UniSTSGRCh37
Build 365115,602,488 - 115,602,838RGDNCBI36
Celera5111,524,122 - 111,524,472RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,755,454 - 110,755,804UniSTS
G65698  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,521,367 - 115,521,611UniSTSGRCh37
Build 365115,549,266 - 115,549,510RGDNCBI36
Celera5111,470,868 - 111,471,112RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,702,126 - 110,702,370UniSTS
STS-H82747  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,420,423 - 115,420,557UniSTSGRCh37
Build 365115,448,322 - 115,448,456RGDNCBI36
Celera5111,368,823 - 111,368,957RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,601,158 - 110,601,292UniSTS
GeneMap99-GB4 RH Map5473.64UniSTS
STS-H92882  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,628,724 - 115,628,901UniSTSGRCh37
Build 365115,656,623 - 115,656,800RGDNCBI36
Celera5111,578,260 - 111,578,437RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,809,265 - 110,809,442UniSTS
GeneMap99-GB4 RH Map5474.2UniSTS
NCBI RH Map5826.1UniSTS
RH66590  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,552,659 - 115,552,824UniSTSGRCh37
Build 365115,580,558 - 115,580,723RGDNCBI36
Celera5111,502,191 - 111,502,356RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,733,523 - 110,733,688UniSTS
GeneMap99-GB4 RH Map5478.64UniSTS
NCBI RH Map5826.1UniSTS
stSG629961  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371662,527,555 - 62,528,901UniSTSGRCh37
GRCh375115,419,174 - 115,420,406UniSTSGRCh37
Build 365115,447,073 - 115,448,305RGDNCBI36
Celera1647,031,465 - 47,032,811RGD
HuRef1648,396,462 - 48,397,808UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1943 1785 1412 334 1131 195 2765 1035 1578 363 1180 1548 154 1 1085 1554 5 2
Low 494 1197 314 290 812 270 1592 1161 2156 56 280 65 21 119 1234 1
Below cutoff 1 9 8 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001308080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_016144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC010296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC018752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC034236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC109456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF078857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF161423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW128995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW662195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY542165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI859871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA001572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB300445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY134365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY139221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF510880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000274458   ⟹   ENSP00000274458
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,085,025 - 116,293,287 (+)Ensembl
RefSeq Acc Id: ENST00000503424
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,292,457 - 116,412,762 (+)Ensembl
RefSeq Acc Id: ENST00000506589   ⟹   ENSP00000424611
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,091,079 - 116,292,916 (+)Ensembl
RefSeq Acc Id: ENST00000507356   ⟹   ENSP00000422448
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,085,016 - 116,292,718 (+)Ensembl
RefSeq Acc Id: ENST00000508250
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,291,539 - 116,306,923 (+)Ensembl
RefSeq Acc Id: ENST00000515539   ⟹   ENSP00000427319
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,085,474 - 116,292,657 (+)Ensembl
RefSeq Acc Id: ENST00000632434   ⟹   ENSP00000488332
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,085,026 - 116,293,286 (+)Ensembl
RefSeq Acc Id: NM_001308080   ⟹   NP_001295009
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385116,085,462 - 116,293,287 (+)NCBI
CHM1_15114,853,933 - 115,061,559 (+)NCBI
T2T-CHM13v2.05116,597,848 - 116,805,723 (+)NCBI
Sequence:
RefSeq Acc Id: NM_016144   ⟹   NP_057228
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385116,085,025 - 116,293,287 (+)NCBI
GRCh375115,420,727 - 115,628,978 (+)RGD
Build 365115,448,626 - 115,656,880 (+)NCBI Archive
Celera5111,369,127 - 111,578,514 (+)RGD
HuRef5110,601,462 - 110,809,519 (+)ENTREZGENE
CHM1_15114,853,447 - 115,061,559 (+)NCBI
T2T-CHM13v2.05116,597,411 - 116,805,723 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146218
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385116,085,025 - 116,190,941 (+)NCBI
T2T-CHM13v2.05116,597,411 - 116,703,350 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146219
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385116,085,278 - 116,190,941 (+)NCBI
T2T-CHM13v2.05116,597,664 - 116,703,350 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146220
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385116,085,025 - 116,190,941 (+)NCBI
T2T-CHM13v2.05116,597,411 - 116,703,350 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_057228   ⟸   NM_016144
- Peptide Label: isoform a
- UniProtKB: D3DT07 (UniProtKB/Swiss-Prot),   Q9P077 (UniProtKB/Swiss-Prot),   Q9Y6G5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001295009   ⟸   NM_001308080
- Peptide Label: isoform b
- UniProtKB: D6RJ90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000424611   ⟸   ENST00000506589
RefSeq Acc Id: ENSP00000422448   ⟸   ENST00000507356
RefSeq Acc Id: ENSP00000274458   ⟸   ENST00000274458
RefSeq Acc Id: ENSP00000488332   ⟸   ENST00000632434
RefSeq Acc Id: ENSP00000427319   ⟸   ENST00000515539
Protein Domains
COMM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Y6G5-F1-model_v2 AlphaFold Q9Y6G5 1-202 view protein structure

Promoters
RGD ID:6802974
Promoter ID:HG_KWN:50863
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000274458
Position:
Human AssemblyChrPosition (strand)Source
Build 365115,447,956 - 115,448,977 (+)MPROMDB
RGD ID:6870332
Promoter ID:EPDNEW_H8331
Type:multiple initiation site
Name:COMMD10_2
Description:COMM domain containing 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H8332  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385116,075,388 - 116,075,448EPDNEW
RGD ID:6870340
Promoter ID:EPDNEW_H8332
Type:initiation region
Name:COMMD10_1
Description:COMM domain containing 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H8331  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385116,085,025 - 116,085,085EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30201 AgrOrtholog
COSMIC COMMD10 COSMIC
Ensembl Genes ENSG00000145781 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000274458 ENTREZGENE
  ENST00000274458.9 UniProtKB/Swiss-Prot
  ENST00000506589.1 UniProtKB/TrEMBL
  ENST00000507356.5 UniProtKB/TrEMBL
  ENST00000515539 ENTREZGENE
  ENST00000515539.5 UniProtKB/TrEMBL
  ENST00000632434.1 UniProtKB/TrEMBL
GTEx ENSG00000145781 GTEx
HGNC ID HGNC:30201 ENTREZGENE
Human Proteome Map COMMD10 Human Proteome Map
InterPro COMM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  COMMD10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:51397 UniProtKB/Swiss-Prot
NCBI Gene 51397 ENTREZGENE
OMIM 616704 OMIM
PANTHER COMM DOMAIN-CONTAINING PROTEIN 10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12333 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COMM_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  COMM_HN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134862606 PharmGKB
PROSITE COMM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt COMDA_HUMAN UniProtKB/Swiss-Prot
  D3DT07 ENTREZGENE
  D6RC04_HUMAN UniProtKB/TrEMBL
  D6RJ90 ENTREZGENE, UniProtKB/TrEMBL
  H0Y9N4_HUMAN UniProtKB/TrEMBL
  L8EAU8_HUMAN UniProtKB/TrEMBL
  Q9P077 ENTREZGENE
  Q9Y6G5 ENTREZGENE
UniProt Secondary D3DT07 UniProtKB/Swiss-Prot
  Q9P077 UniProtKB/Swiss-Prot