ZNF24 (zinc finger protein 24) - Rat Genome Database

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Gene: ZNF24 (zinc finger protein 24) Homo sapiens
Analyze
Symbol: ZNF24
Name: zinc finger protein 24
RGD ID: 1344102
HGNC Page HGNC:13032
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: KOX17; lacks zinc finger domain; retinoic acid suppression protein A; RSG-A; Zfp191; zinc finger and SCAN domain-containing protein 3; zinc finger protein 191; zinc finger protein 24 (KOX 17); zinc finger protein KOX17; ZNF191; ZSCAN3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381835,332,227 - 35,344,420 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1835,332,227 - 35,345,482 (-)EnsemblGRCh38hg38GRCh38
GRCh371832,912,191 - 32,924,384 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361831,169,957 - 31,178,405 (-)NCBINCBI36Build 36hg18NCBI36
Build 341831,169,956 - 31,178,403NCBI
Celera1829,720,074 - 29,732,324 (-)NCBICelera
Cytogenetic Map18q12.2NCBI
HuRef1829,771,791 - 29,784,041 (-)NCBIHuRef
CHM1_11832,839,132 - 32,851,381 (-)NCBICHM1_1
T2T-CHM13v2.01835,523,566 - 35,535,760 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IDA)
nucleus  (IEA,ISS)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2004757   PMID:2288909   PMID:8889548   PMID:10567577   PMID:10585455   PMID:11532988   PMID:12477932   PMID:12801647   PMID:14499622   PMID:14702039   PMID:15489334   PMID:15561718  
PMID:15592455   PMID:16169070   PMID:16189514   PMID:17270462   PMID:18029348   PMID:18472161   PMID:19060904   PMID:19274049   PMID:19463170   PMID:19544452   PMID:19615732   PMID:20195357  
PMID:20211142   PMID:20453000   PMID:20510677   PMID:20562859   PMID:21382349   PMID:21516116   PMID:21532573   PMID:21549307   PMID:21873635   PMID:22213192   PMID:22678762   PMID:22902626  
PMID:22939629   PMID:23212515   PMID:24224020   PMID:24711643   PMID:25416956   PMID:25550468   PMID:25910212   PMID:26186194   PMID:26317898   PMID:26344197   PMID:26972000   PMID:27545878  
PMID:27637333   PMID:28514442   PMID:28813667   PMID:29121065   PMID:29180619   PMID:29395067   PMID:29467281   PMID:29509190   PMID:29844126   PMID:29892012   PMID:30154076   PMID:31091453  
PMID:31403225   PMID:31452512   PMID:31515488   PMID:31527615   PMID:31753913   PMID:32203420   PMID:32239614   PMID:32296183   PMID:32814053   PMID:32891193   PMID:32989298   PMID:33001583  
PMID:33187986   PMID:33197287   PMID:33742100   PMID:33961781   PMID:34079125   PMID:34091597   PMID:34189442   PMID:34597346   PMID:34921745   PMID:35013556   PMID:35092191   PMID:35140242  
PMID:35182466   PMID:35563538   PMID:35792897   PMID:35831314   PMID:35944360   PMID:36089195   PMID:36232890   PMID:36273042   PMID:36835656   PMID:37689310   PMID:38297188  


Genomics

Comparative Map Data
ZNF24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381835,332,227 - 35,344,420 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1835,332,227 - 35,345,482 (-)EnsemblGRCh38hg38GRCh38
GRCh371832,912,191 - 32,924,384 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361831,169,957 - 31,178,405 (-)NCBINCBI36Build 36hg18NCBI36
Build 341831,169,956 - 31,178,403NCBI
Celera1829,720,074 - 29,732,324 (-)NCBICelera
Cytogenetic Map18q12.2NCBI
HuRef1829,771,791 - 29,784,041 (-)NCBIHuRef
CHM1_11832,839,132 - 32,851,381 (-)NCBICHM1_1
T2T-CHM13v2.01835,523,566 - 35,535,760 (-)NCBIT2T-CHM13v2.0
Zfp24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391824,142,774 - 24,155,294 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1824,142,759 - 24,153,867 (-)EnsemblGRCm39 Ensembl
GRCm381824,009,717 - 24,020,813 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1824,009,702 - 24,020,810 (-)EnsemblGRCm38mm10GRCm38
MGSCv371824,170,768 - 24,179,272 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361824,155,277 - 24,163,781 (-)NCBIMGSCv36mm8
Celera1824,502,320 - 24,510,829 (-)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1812.55NCBI
Zfp24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81815,573,031 - 15,583,432 (-)NCBIGRCr8
mRatBN7.21815,295,687 - 15,307,319 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1815,298,290 - 15,306,799 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1815,485,141 - 15,492,250 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01816,267,846 - 16,274,955 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01815,557,596 - 15,564,706 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01815,910,175 - 15,921,757 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1815,914,399 - 15,921,734 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01815,675,784 - 15,687,354 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41815,782,909 - 15,790,125 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11815,809,563 - 15,816,771 (-)NCBI
Celera1815,248,039 - 15,255,255 (-)NCBICelera
Cytogenetic Map18p12NCBI
Znf24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540222,067,261 - 22,079,216 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540222,067,261 - 22,079,216 (-)NCBIChiLan1.0ChiLan1.0
ZNF24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21752,721,511 - 52,734,457 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11838,414,102 - 38,430,756 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01828,551,197 - 28,563,351 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11832,139,846 - 32,152,397 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1832,144,853 - 32,152,242 (-)Ensemblpanpan1.1panPan2
ZNF24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1754,691,212 - 54,702,249 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl754,691,555 - 54,697,183 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha754,117,106 - 54,127,901 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0754,662,616 - 54,673,411 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl754,662,723 - 54,670,299 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1754,345,258 - 54,372,911 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0754,368,570 - 54,379,364 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0754,661,702 - 54,689,042 (+)NCBIUU_Cfam_GSD_1.0
Znf24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494450,416,647 - 50,427,741 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365179,743,973 - 9,752,449 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365179,744,087 - 9,752,346 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6119,160,530 - 119,167,187 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16119,156,507 - 119,167,240 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26111,615,234 - 111,625,806 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11845,418,556 - 45,430,743 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1845,418,568 - 45,425,743 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605019,920,846 - 19,933,200 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247799,732,615 - 9,739,497 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247799,727,764 - 9,739,442 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZNF24
8 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 18q12.1-12.3(chr18:31655749-42564094)x3 copy number gain See cases [RCV000050773] Chr18:31655749..42564094 [GRCh38]
Chr18:29235712..40144059 [GRCh37]
Chr18:27489710..38398057 [NCBI36]
Chr18:18q12.1-12.3		 pathogenic
GRCh38/hg38 18q12.1-12.3(chr18:29444510-40403652)x1 copy number loss See cases [RCV000051090] Chr18:29444510..40403652 [GRCh38]
Chr18:27024475..37983616 [GRCh37]
Chr18:25278473..36237614 [NCBI36]
Chr18:18q12.1-12.3		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:148963-80252149)x3 copy number gain See cases [RCV000051048] Chr18:148963..80252149 [GRCh38]
Chr18:148963..78010032 [GRCh37]
Chr18:138963..76111023 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q11.1-23(chr18:20960320-80234429)x3 copy number gain See cases [RCV000052543] Chr18:20960320..80234429 [GRCh38]
Chr18:18540281..77992312 [GRCh37]
Chr18:16794279..76093303 [NCBI36]
Chr18:18q11.1-23		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:53345-80209986)x3 copy number gain See cases [RCV000052501] Chr18:53345..80209986 [GRCh38]
Chr18:53345..77967869 [GRCh37]
Chr18:43345..76068860 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q11.1-23(chr18:20989762-80209986)x3 copy number gain See cases [RCV000052549] Chr18:20989762..80209986 [GRCh38]
Chr18:18569723..77967869 [GRCh37]
Chr18:16823721..76068860 [NCBI36]
Chr18:18q11.1-23		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:148763-80252290)x3 copy number gain See cases [RCV000052507] Chr18:148763..80252290 [GRCh38]
Chr18:148763..78010173 [GRCh37]
Chr18:138763..76111164 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q12.1-22.1(chr18:29249202-65448117)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052563]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052563]|See cases [RCV000052563] Chr18:29249202..65448117 [GRCh38]
Chr18:26829167..63115353 [GRCh37]
Chr18:25083165..61266333 [NCBI36]
Chr18:18q12.1-22.1		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:148963-80244381)x3 copy number gain See cases [RCV000052514] Chr18:148963..80244381 [GRCh38]
Chr18:148963..78002264 [GRCh37]
Chr18:138963..76103255 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q12.1-12.2(chr18:35097761-39379288)x3 copy number gain See cases [RCV000052567] Chr18:35097761..39379288 [GRCh38]
Chr18:32677725..36959252 [GRCh37]
Chr18:30931723..35213250 [NCBI36]
Chr18:18q12.1-12.2		 pathogenic
GRCh38/hg38 18q12.1-12.3(chr18:32111530-44070219)x1 copy number loss See cases [RCV000053829] Chr18:32111530..44070219 [GRCh38]
Chr18:29691493..41650184 [GRCh37]
Chr18:27945491..39904182 [NCBI36]
Chr18:18q12.1-12.3		 pathogenic
GRCh38/hg38 18q12.1-12.3(chr18:34047118-41394354)x1 copy number loss See cases [RCV000053830] Chr18:34047118..41394354 [GRCh38]
Chr18:31627082..38974318 [GRCh37]
Chr18:29881080..37228316 [NCBI36]
Chr18:18q12.1-12.3		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:149089-80234391)x3 copy number gain See cases [RCV000134110] Chr18:149089..80234391 [GRCh38]
Chr18:149089..77992274 [GRCh37]
Chr18:139089..76093265 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q12.1-23(chr18:32123105-80252149)x3 copy number gain See cases [RCV000136890] Chr18:32123105..80252149 [GRCh38]
Chr18:29703068..78010032 [GRCh37]
Chr18:27957066..76111023 [NCBI36]
Chr18:18q12.1-23		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:118760-80254946)x3 copy number gain See cases [RCV000138656] Chr18:118760..80254946 [GRCh38]
Chr18:118760..78012829 [GRCh37]
Chr18:108760..76113817 [NCBI36]
Chr18:18p11.32-q23		 pathogenic|conflicting data from submitters
GRCh38/hg38 18q12.1-12.2(chr18:33373798-37364748)x1 copy number loss See cases [RCV000138295] Chr18:33373798..37364748 [GRCh38]
Chr18:30953762..34944711 [GRCh37]
Chr18:29207760..33198709 [NCBI36]
Chr18:18q12.1-12.2		 likely pathogenic
GRCh38/hg38 18p11.32-q23(chr18:149089-80254936)x3 copy number gain See cases [RCV000139397] Chr18:149089..80254936 [GRCh38]
Chr18:149089..78012819 [GRCh37]
Chr18:139089..76113807 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:136227-80256240)x3 copy number gain See cases [RCV000142244] Chr18:136227..80256240 [GRCh38]
Chr18:136227..78014123 [GRCh37]
Chr18:126227..76115097 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q11.1-12.3(chr18:20941324-40360620)x3 copy number gain See cases [RCV000142226] Chr18:20941324..40360620 [GRCh38]
Chr18:18521285..37940584 [GRCh37]
Chr18:16775283..36194582 [NCBI36]
Chr18:18q11.1-12.3		 pathogenic
GRCh38/hg38 18q11.1-22.3(chr18:20962119-74691446)x3 copy number gain See cases [RCV000143057] Chr18:20962119..74691446 [GRCh38]
Chr18:18542080..72403402 [GRCh37]
Chr18:16796078..70532390 [NCBI36]
Chr18:18q11.1-22.3		 pathogenic
GRCh38/hg38 18q12.1-12.2(chr18:34454080-35755377)x3 copy number gain See cases [RCV000142876] Chr18:34454080..35755377 [GRCh38]
Chr18:32034044..33335341 [GRCh37]
Chr18:30288042..31589339 [NCBI36]
Chr18:18q12.1-12.2		 uncertain significance
GRCh38/hg38 18p11.32-q23(chr18:136226-80256240)x3 copy number gain See cases [RCV000143218] Chr18:136226..80256240 [GRCh38]
Chr18:136226..78014123 [GRCh37]
Chr18:126226..76115097 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:148963-80252149)x3 copy number gain See cases [RCV000148072] Chr18:148963..80252149 [GRCh38]
Chr18:148963..78010032 [GRCh37]
Chr18:138963..76111023 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:163323-78005236)x3 copy number gain See cases [RCV000240130] Chr18:163323..78005236 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18q11.1-23(chr18:18548019-77954165)x3 copy number gain See cases [RCV000240476] Chr18:18548019..77954165 [GRCh37]
Chr18:18q11.1-23		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:136226-78014123)x3 copy number gain See cases [RCV000446047] Chr18:136226..78014123 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:163323-78005185)x3 copy number gain See cases [RCV000445851] Chr18:163323..78005185 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18q11.2-12.2(chr18:20069932-36887326)x1 copy number loss See cases [RCV000510691] Chr18:20069932..36887326 [GRCh37]
Chr18:18q11.2-12.2		 pathogenic
GRCh37/hg19 18p11.32-q21.1(chr18:136227-46171053)x3 copy number gain See cases [RCV000511857] Chr18:136227..46171053 [GRCh37]
Chr18:18p11.32-q21.1		 pathogenic
GRCh37/hg19 18q12.1-12.2(chr18:30368042-36078516)x1 copy number loss See cases [RCV000511858] Chr18:30368042..36078516 [GRCh37]
Chr18:18q12.1-12.2		 likely pathogenic
GRCh37/hg19 18q11.1-22.1(chr18:18521285-64495798)x3 copy number gain See cases [RCV000511734] Chr18:18521285..64495798 [GRCh37]
Chr18:18q11.1-22.1		 pathogenic
GRCh37/hg19 18p11.21-q23(chr18:14869204-78014123)x3 copy number gain See cases [RCV000512030] Chr18:14869204..78014123 [GRCh37]
Chr18:18p11.21-q23		 pathogenic
GRCh37/hg19 18q11.2-21.1(chr18:24835114-46917217)x3 copy number gain See cases [RCV000511124] Chr18:24835114..46917217 [GRCh37]
Chr18:18q11.2-21.1		 likely benign
GRCh37/hg19 18p11.32-q23(chr18:136227-78014123) copy number gain See cases [RCV000511189] Chr18:136227..78014123 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18q12.1-23(chr18:31879854-78014123)x3 copy number gain See cases [RCV000512425] Chr18:31879854..78014123 [GRCh37]
Chr18:18q12.1-23		 pathogenic
GRCh37/hg19 18q12.1-12.2(chr18:29711972-35866193)x1 copy number loss not provided [RCV000684043] Chr18:29711972..35866193 [GRCh37]
Chr18:18q12.1-12.2		 pathogenic
GRCh37/hg19 18q11.1-21.2(chr18:18539806-49926444)x2 copy number gain not provided [RCV000739776] Chr18:18539806..49926444 [GRCh37]
Chr18:18q11.1-21.2		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:12842-78015180)x3 copy number gain not provided [RCV000752245] Chr18:12842..78015180 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:13034-78015180)x3 copy number gain not provided [RCV000752246] Chr18:13034..78015180 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18q11.2-12.2(chr18:22868759-34335753)x1 copy number loss not provided [RCV001006964] Chr18:22868759..34335753 [GRCh37]
Chr18:18q11.2-12.2		 pathogenic
GRCh37/hg19 18q11.2-21.2(chr18:20689919-49455212)x3 copy number gain not provided [RCV001006980] Chr18:20689919..49455212 [GRCh37]
Chr18:18q11.2-21.2		 pathogenic
GRCh37/hg19 18q11.2-23(chr18:23626739-78014976)x3 copy number gain not provided [RCV001537911] Chr18:23626739..78014976 [GRCh37]
Chr18:18q11.2-23		 pathogenic
GRCh37/hg19 18q11.2-12.2(chr18:23971647-33737300)x1 copy number loss See cases [RCV001263022] Chr18:23971647..33737300 [GRCh37]
Chr18:18q11.2-12.2		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:1-78077248) copy number gain Trisomy 18 [RCV002280660] Chr18:1..78077248 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
Single allele deletion Intellectual disability [RCV001787257] Chr18:1262336..53254747 [GRCh37]
Chr18:18p11.32-q21.2		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:136226-78014123) copy number gain not specified [RCV002052616] Chr18:136226..78014123 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
NM_006965.4(ZNF24):c.733C>T (p.Pro245Ser) single nucleotide variant not specified [RCV004076663] Chr18:35337606 [GRCh38]
Chr18:32917570 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_006965.4(ZNF24):c.437G>A (p.Arg146Gln) single nucleotide variant not specified [RCV004219577] Chr18:35339960 [GRCh38]
Chr18:32919924 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_006965.4(ZNF24):c.311T>C (p.Leu104Pro) single nucleotide variant not specified [RCV004100537] Chr18:35340340 [GRCh38]
Chr18:32920304 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_006965.4(ZNF24):c.733C>A (p.Pro245Thr) single nucleotide variant not specified [RCV004168157] Chr18:35337606 [GRCh38]
Chr18:32917570 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_006965.4(ZNF24):c.352G>C (p.Glu118Gln) single nucleotide variant not specified [RCV004178654] Chr18:35340299 [GRCh38]
Chr18:32920263 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_006965.4(ZNF24):c.120C>G (p.Ile40Met) single nucleotide variant not specified [RCV004318195] Chr18:35340531 [GRCh38]
Chr18:32920495 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_006965.4(ZNF24):c.479A>C (p.Glu160Ala) single nucleotide variant not specified [RCV004260312] Chr18:35339918 [GRCh38]
Chr18:32919882 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_006965.4(ZNF24):c.670C>A (p.Pro224Thr) single nucleotide variant not specified [RCV004297462] Chr18:35337669 [GRCh38]
Chr18:32917633 [GRCh37]
Chr18:18q12.2		 uncertain significance
GRCh37/hg19 18q12.1-12.3(chr18:26595964-38643072)x1 copy number loss not provided [RCV003483335] Chr18:26595964..38643072 [GRCh37]
Chr18:18q12.1-12.3		 pathogenic
NM_006965.4(ZNF24):c.496A>G (p.Ser166Gly) single nucleotide variant not specified [RCV004493994] Chr18:35339901 [GRCh38]
Chr18:32919865 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_006965.4(ZNF24):c.103G>A (p.Glu35Lys) single nucleotide variant not specified [RCV004493993] Chr18:35340548 [GRCh38]
Chr18:32920512 [GRCh37]
Chr18:18q12.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:7021
Count of miRNA genes:1214
Interacting mature miRNAs:1567
Transcripts:ENST00000261332, ENST00000399061, ENST00000589539, ENST00000589881, ENST00000590140, ENST00000593130
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH91536  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371832,912,387 - 32,912,553UniSTSGRCh37
Build 361831,166,385 - 31,166,551RGDNCBI36
Celera1829,720,283 - 29,720,449RGD
Cytogenetic Map18q12UniSTS
HuRef1829,772,000 - 29,772,166UniSTS
RH103604  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371832,915,240 - 32,915,415UniSTSGRCh37
Build 361831,169,238 - 31,169,413RGDNCBI36
Celera1829,723,137 - 29,723,312RGD
Cytogenetic Map18q12UniSTS
HuRef1829,774,854 - 29,775,029UniSTS
SHGC-37487  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371832,923,381 - 32,923,530UniSTSGRCh37
Build 361831,177,379 - 31,177,528RGDNCBI36
Celera1829,731,279 - 29,731,428RGD
Cytogenetic Map18q12UniSTS
HuRef1829,782,996 - 29,783,145UniSTS
GeneMap99-G3 RH Map181118.0UniSTS
D18S1233  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371832,917,205 - 32,917,482UniSTSGRCh37
GRCh371832,917,205 - 32,917,315UniSTSGRCh37
Build 361831,171,203 - 31,171,313RGDNCBI36
Celera1829,725,102 - 29,725,379UniSTS
Celera1829,725,102 - 29,725,212RGD
Cytogenetic Map18q12UniSTS
HuRef1829,776,819 - 29,777,096UniSTS
Whitehead-YAC Contig Map18 UniSTS
A009Q31  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371832,913,722 - 32,913,822UniSTSGRCh37
Build 361831,167,720 - 31,167,820RGDNCBI36
Celera1829,721,618 - 29,721,718RGD
Cytogenetic Map18q12UniSTS
HuRef1829,773,335 - 29,773,435UniSTS
GeneMap99-GB4 RH Map18290.24UniSTS
STS-W73139  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371832,912,191 - 32,912,431UniSTSGRCh37
Build 361831,166,189 - 31,166,429RGDNCBI36
Celera1829,720,087 - 29,720,327RGD
Cytogenetic Map18q12UniSTS
HuRef1829,771,804 - 29,772,044UniSTS
GeneMap99-GB4 RH Map18270.04UniSTS
G32784  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371832,913,722 - 32,913,822UniSTSGRCh37
Celera1829,721,618 - 29,721,718UniSTS
Cytogenetic Map18q12UniSTS
HuRef1829,773,335 - 29,773,435UniSTS
RH48366  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371832,918,910 - 32,919,851UniSTSGRCh37
Celera1829,726,808 - 29,727,749UniSTS
Cytogenetic Map18q12UniSTS
HuRef1829,778,525 - 29,779,466UniSTS
GeneMap99-GB4 RH Map18268.83UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2353 1915 1566 489 1382 332 4072 1742 3182 342 1444 1606 173 1 1185 2555 6 2
Low 86 1075 160 135 568 133 285 455 552 77 16 7 2 19 233
Below cutoff 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001308123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001375815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC116447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF016052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF038964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF542097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK021966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC016801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG436261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT006658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA314100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR450328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY101315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U68536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X52348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000261332   ⟹   ENSP00000261332
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1835,332,227 - 35,344,420 (-)Ensembl
RefSeq Acc Id: ENST00000399061   ⟹   ENSP00000382015
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1835,332,227 - 35,344,456 (-)Ensembl
RefSeq Acc Id: ENST00000589539   ⟹   ENSP00000467608
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1835,340,345 - 35,343,932 (-)Ensembl
RefSeq Acc Id: ENST00000589881   ⟹   ENSP00000467655
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1835,332,227 - 35,340,654 (-)Ensembl
RefSeq Acc Id: ENST00000590140   ⟹   ENSP00000467432
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1835,340,235 - 35,345,482 (-)Ensembl
RefSeq Acc Id: ENST00000593130   ⟹   ENSP00000467924
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1835,340,363 - 35,342,675 (-)Ensembl
RefSeq Acc Id: NM_001308123   ⟹   NP_001295052
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381835,332,227 - 35,344,420 (-)NCBI
CHM1_11832,845,803 - 32,851,386 (-)NCBI
T2T-CHM13v2.01835,523,566 - 35,535,760 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001375815   ⟹   NP_001362744
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381835,332,227 - 35,344,420 (-)NCBI
T2T-CHM13v2.01835,523,566 - 35,535,760 (-)NCBI
Sequence:
RefSeq Acc Id: NM_006965   ⟹   NP_008896
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381835,332,227 - 35,344,420 (-)NCBI
GRCh371832,912,178 - 32,924,428 (-)NCBI
Build 361831,169,957 - 31,178,405 (-)NCBI Archive
HuRef1829,771,791 - 29,784,041 (-)ENTREZGENE
CHM1_11832,839,126 - 32,851,386 (-)NCBI
T2T-CHM13v2.01835,523,566 - 35,535,760 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_008896   ⟸   NM_006965
- Peptide Label: isoform 1
- UniProtKB: Q6ICR5 (UniProtKB/Swiss-Prot),   Q53YE4 (UniProtKB/Swiss-Prot),   O14754 (UniProtKB/Swiss-Prot),   Q8IZN4 (UniProtKB/Swiss-Prot),   P17028 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001295052   ⟸   NM_001308123
- Peptide Label: isoform 2
- UniProtKB: P17028 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001362744   ⟸   NM_001375815
- Peptide Label: isoform 1
- UniProtKB: Q6ICR5 (UniProtKB/Swiss-Prot),   Q53YE4 (UniProtKB/Swiss-Prot),   P17028 (UniProtKB/Swiss-Prot),   O14754 (UniProtKB/Swiss-Prot),   Q8IZN4 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSP00000382015   ⟸   ENST00000399061
RefSeq Acc Id: ENSP00000467608   ⟸   ENST00000589539
RefSeq Acc Id: ENSP00000467655   ⟸   ENST00000589881
RefSeq Acc Id: ENSP00000261332   ⟸   ENST00000261332
RefSeq Acc Id: ENSP00000467432   ⟸   ENST00000590140
RefSeq Acc Id: ENSP00000467924   ⟸   ENST00000593130
Protein Domains
SCAN box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P17028-F1-model_v2 AlphaFold P17028 1-368 view protein structure

Promoters
RGD ID:6795069
Promoter ID:HG_KWN:27882
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:UC002KYU.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361831,174,086 - 31,174,586 (-)MPROMDB
RGD ID:6795068
Promoter ID:HG_KWN:27883
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000255769,   UC002KYT.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361831,178,016 - 31,178,517 (-)MPROMDB
RGD ID:7237179
Promoter ID:EPDNEW_H24335
Type:initiation region
Name:ZNF24_1
Description:zinc finger protein 24
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381835,344,420 - 35,344,480EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:13032 AgrOrtholog
COSMIC ZNF24 COSMIC
Ensembl Genes ENSG00000172466 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000261332 ENTREZGENE
  ENST00000261332.11 UniProtKB/Swiss-Prot
  ENST00000399061 ENTREZGENE
  ENST00000399061.3 UniProtKB/Swiss-Prot
  ENST00000589539.1 UniProtKB/TrEMBL
  ENST00000589881 ENTREZGENE
  ENST00000589881.5 UniProtKB/Swiss-Prot
  ENST00000590140.1 UniProtKB/TrEMBL
  ENST00000593130.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.4020.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot
GTEx ENSG00000172466 GTEx
HGNC ID HGNC:13032 ENTREZGENE
Human Proteome Map ZNF24 Human Proteome Map
InterPro SCAN_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCAN_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report hsa:7572 UniProtKB/Swiss-Prot
NCBI Gene 7572 ENTREZGENE
OMIM 194534 OMIM
PANTHER PROTEIN ZBED8-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCAN DOMAIN-CONTAINING PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SCAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot
PharmGKB PA37610 PharmGKB
PROSITE SCAN_BOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART SCAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP Retrovirus capsid dimerization domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot
UniProt K7EPL1_HUMAN UniProtKB/TrEMBL
  K7EPZ8_HUMAN UniProtKB/TrEMBL
  K7EQP8_HUMAN UniProtKB/TrEMBL
  O14754 ENTREZGENE
  P17028 ENTREZGENE
  Q53YE4 ENTREZGENE
  Q6ICR5 ENTREZGENE
  Q8IZN4 ENTREZGENE
  ZNF24_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary O14754 UniProtKB/Swiss-Prot
  Q53YE4 UniProtKB/Swiss-Prot
  Q6ICR5 UniProtKB/Swiss-Prot
  Q8IZN4 UniProtKB/Swiss-Prot