IFRD2 (interferon related developmental regulator 2)

Gene: IFRD2 (interferon related developmental regulator 2) Homo sapiens

Analyze

Symbol:

IFRD2

Name:

interferon related developmental regulator 2

RGD ID:

1320999

HGNC Page

HGNC:5457

Description:

Enables ribosome binding activity and translation repressor activity. Involved in negative regulation of translation. Located in nucleus.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

FLJ40446; IFNRP; interferon-related developmental regulator 2; interferon-related protein; SKMc15; SM15

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	50,287,732 - 50,292,429 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	50,287,732 - 50,292,918 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	50,325,163 - 50,329,860 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	50,300,124 - 50,304,923 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	50,300,123 - 50,304,923	NCBI
Celera	3	50,297,995 - 50,302,857 (-)	NCBI		Celera
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	50,380,906 - 50,385,769 (-)	NCBI		HuRef
CHM1_1	3	50,277,469 - 50,282,332 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	50,317,089 - 50,321,785 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 1 (IAGP)

developmental and epileptic encephalopathy (IAGP)

early infantile epileptic encephalopathy (IAGP)

primary ciliary dyskinesia (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

14-Deoxy-11,12-didehydroandrographolide (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (ISO)

2-butoxyethanol (ISO)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (ISO)

4-hydroxyphenyl retinamide (ISO)

acrolein (EXP)

acrylamide (EXP)

all-trans-retinoic acid (EXP)

alpha-pinene (EXP)

antimycin A (EXP)

Aroclor 1254 (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

bortezomib (EXP)

bucladesine (EXP)

cadmium dichloride (ISO)

cobalt dichloride (EXP)

coumestrol (EXP)

crocidolite asbestos (ISO)

cyclosporin A (EXP)

daidzein (EXP)

deguelin (EXP)

diazinon (EXP)

dibutyl phthalate (ISO)

dioxygen (EXP)

disodium selenite (EXP)

elemental selenium (EXP)

endosulfan (ISO)

Enterolactone (EXP)

ethyl methanesulfonate (EXP)

fenthion (ISO)

flutamide (ISO)

folic acid (ISO)

formaldehyde (EXP)

furan (ISO)

gallic acid (EXP)

genistein (EXP)

gentamycin (ISO)

glycidyl methacrylate (EXP)

glycitein (EXP)

glyphosate (ISO)

inulin (ISO)

medroxyprogesterone acetate (EXP)

methidathion (ISO)

methyl methanesulfonate (EXP)

methylseleninic acid (EXP)

nefazodone (ISO)

nickel atom (EXP)

nimesulide (ISO)

oxaliplatin (ISO)

ozone (EXP,ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorononanoic acid (EXP)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

picoxystrobin (EXP)

pirinixic acid (ISO)

pyrimidifen (EXP)

resveratrol (EXP)

rotenone (EXP,ISO)

selenium atom (EXP)

sodium arsenite (ISO)

sunitinib (EXP)

tetrachloromethane (ISO)

thioacetamide (ISO)

topotecan (ISO)

trichloroethene (ISO)

triptonide (ISO)

trovafloxacin (ISO)

uranium atom (EXP)

urethane (EXP)

valproic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of translation (IDA)

regulation of translation (IEA)

Cellular Component

nucleus (HDA)

Molecular Function

protein binding (IPI)

ribosome binding (IDA)

translation repressor activity (IDA)

References

References - curated

#	Reference Title	Reference Citation
1.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9050919	PMID:9722946	PMID:11085536	PMID:12477932	PMID:14702039	PMID:15489334	PMID:16303743	PMID:18976975	PMID:19615732	PMID:19953087	PMID:20689807	PMID:21044950
PMID:21630459	PMID:21832049	PMID:21903422	PMID:22658674	PMID:24778252	PMID:26344197	PMID:26496610	PMID:26972000	PMID:28514442	PMID:30355441	PMID:30463901	PMID:31527615
PMID:31617661	PMID:32296183	PMID:32513696	PMID:32807901	PMID:32994395	PMID:33961781	PMID:35256949	PMID:35748872	PMID:35915257	PMID:37827155

Genomics

Comparative Map Data

IFRD2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	50,287,732 - 50,292,429 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	50,287,732 - 50,292,918 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	50,325,163 - 50,329,860 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	50,300,124 - 50,304,923 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	50,300,123 - 50,304,923	NCBI
Celera	3	50,297,995 - 50,302,857 (-)	NCBI		Celera
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	50,380,906 - 50,385,769 (-)	NCBI		HuRef
CHM1_1	3	50,277,469 - 50,282,332 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	50,317,089 - 50,321,785 (-)	NCBI		T2T-CHM13v2.0

Ifrd2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	107,464,917 - 107,470,237 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	107,464,841 - 107,470,584 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	107,587,718 - 107,593,038 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	107,587,642 - 107,593,385 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	107,490,049 - 107,495,369 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	107,445,819 - 107,451,139 (+)	NCBI		MGSCv36	mm8
Celera	9	107,196,492 - 107,201,819 (+)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	58.24	NCBI

Ifrd2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,139,612 - 117,144,834 (+)	NCBI		GRCr8
mRatBN7.2	8	108,260,969 - 108,266,191 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,260,969 - 108,266,194 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	113,887,789 - 113,893,023 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,086,946 - 112,092,180 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	109,929,728 - 109,934,962 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	116,343,096 - 116,348,318 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,343,096 - 116,348,314 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	115,699,356 - 115,704,578 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	112,834,734 - 112,839,956 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	112,854,188 - 112,859,131 (+)	NCBI
Celera	8	107,567,547 - 107,572,769 (+)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

Ifrd2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	2,101,202 - 2,104,104 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955532	2,101,202 - 2,106,779 (-)	NCBI	ChiLan1.0	ChiLan1.0

IFRD2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	50,270,799 - 50,276,030 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	50,275,574 - 50,280,436 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	50,216,335 - 50,221,186 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	51,451,086 - 51,455,934 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	51,451,086 - 51,455,934 (-)	Ensembl	panpan1.1		panPan2

IFRD2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	39,047,573 - 39,053,528 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	39,048,259 - 39,053,341 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	38,968,620 - 38,974,571 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	39,403,618 - 39,409,570 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	39,397,514 - 39,409,548 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	38,771,441 - 38,777,392 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	39,174,952 - 39,180,903 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	39,455,021 - 39,460,972 (+)	NCBI		UU_Cfam_GSD_1.0

Ifrd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	65,064,610 - 65,070,600 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	1,823,679 - 1,830,879 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	1,825,107 - 1,831,112 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IFRD2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	32,756,680 - 32,790,672 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	32,756,671 - 32,790,763 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	35,935,219 - 35,969,079 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IFRD2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	11,675,094 - 11,679,953 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	11,675,542 - 11,679,843 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	155,306,236 - 155,311,096 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ifrd2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	4,148,888 - 4,154,496 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	4,148,888 - 4,154,698 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in IFRD2
38 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 3p21.31-14.3(chr3:49461000-55314500)x1	copy number loss	See cases [RCV000051511]	Chr3:49461000..55314500 [GRCh38] Chr3:49498433..55348528 [GRCh37] Chr3:49473437..55323568 [NCBI36] Chr3:3p21.31-14.3	pathogenic
GRCh38/hg38 3p21.31-21.2(chr3:45879883-50749922)x4	copy number gain	See cases [RCV000133650]	Chr3:45879883..50749922 [GRCh38] Chr3:45921375..50787353 [GRCh37] Chr3:45896379..50762357 [NCBI36] Chr3:3p21.31-21.2	pathogenic
GRCh37/hg19 3p21.31(chr3:50273827-50403519)x3	copy number gain	Breast ductal adenocarcinoma [RCV000207033]	Chr3:50273827..50403519 [GRCh37] Chr3:3p21.31	uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)	copy number gain	See cases [RCV000512358]	Chr3:61892..197851986 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3	copy number gain	See cases [RCV000511055]	Chr3:61892..197851986 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3	copy number gain	not provided [RCV000742138]	Chr3:61495..197838262 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3	copy number gain	not provided [RCV000742133]	Chr3:60174..197948027 [GRCh37] Chr3:3p26.3-q29	pathogenic
NM_006764.5(IFRD2):c.237G>C (p.Glu79Asp)	single nucleotide variant	not provided [RCV000950656]	Chr3:50290414 [GRCh38] Chr3:50327845 [GRCh37] Chr3:3p21.31	benign
GRCh37/hg19 3p21.31-21.1(chr3:45153770-53878616)	copy number gain	not provided [RCV000767704]	Chr3:45153770..53878616 [GRCh37] Chr3:3p21.31-21.1	pathogenic
NM_006764.5(IFRD2):c.879C>A (p.Asp293Glu)	single nucleotide variant	not specified [RCV004331143]	Chr3:50289261 [GRCh38] Chr3:50326692 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.1156A>G (p.Asn386Asp)	single nucleotide variant	not specified [RCV004302332]	Chr3:50288501 [GRCh38] Chr3:50325932 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.122G>A (p.Arg41His)	single nucleotide variant	not specified [RCV004305574]	Chr3:50290616 [GRCh38] Chr3:50328047 [GRCh37] Chr3:3p21.31	uncertain significance
GRCh37/hg19 3p21.31-21.2(chr3:48807193-51363558)x1	copy number loss	not provided [RCV001259686]	Chr3:48807193..51363558 [GRCh37] Chr3:3p21.31-21.2	pathogenic
NC_000003.11:g.(?_48507870)_(50340407_?)del	deletion	Aicardi-Goutieres syndrome 1 [RCV001380369]	Chr3:48507870..50340407 [GRCh37] Chr3:3p21.31	pathogenic
NM_006764.5(IFRD2):c.47G>A (p.Arg16His)	single nucleotide variant	not specified [RCV001733638]	Chr3:50292228 [GRCh38] Chr3:50329659 [GRCh37] Chr3:3p21.31	uncertain significance
NC_000003.11:g.(?_49547968)_(50685477_?)del	deletion	Early infantile epileptic encephalopathy with suppression bursts [RCV001970206]	Chr3:49547968..50685477 [GRCh37] Chr3:3p21.31-21.2	pathogenic
NC_000003.11:g.(?_49866536)_(50540854_?)dup	duplication	Primary ciliary dyskinesia [RCV003119656]	Chr3:49866536..50540854 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.-138G>A	single nucleotide variant	not specified [RCV004156063]	Chr3:50292412 [GRCh38] Chr3:50329843 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.65G>A (p.Arg22Gln)	single nucleotide variant	not specified [RCV004144248]	Chr3:50290673 [GRCh38] Chr3:50328104 [GRCh37] Chr3:3p21.31	likely benign
NM_006764.5(IFRD2):c.690C>G (p.Ser230Arg)	single nucleotide variant	not specified [RCV004088528]	Chr3:50289536 [GRCh38] Chr3:50326967 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.346C>T (p.Arg116Cys)	single nucleotide variant	not specified [RCV004212456]	Chr3:50290212 [GRCh38] Chr3:50327643 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.1174A>G (p.Ile392Val)	single nucleotide variant	not specified [RCV004169756]	Chr3:50288483 [GRCh38] Chr3:50325914 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.5C>G (p.Pro2Arg)	single nucleotide variant	not specified [RCV004103934]	Chr3:50292270 [GRCh38] Chr3:50329701 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.955A>G (p.Lys319Glu)	single nucleotide variant	not specified [RCV004172153]	Chr3:50288868 [GRCh38] Chr3:50326299 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.-123C>A	single nucleotide variant	not specified [RCV004074206]	Chr3:50292397 [GRCh38] Chr3:50329828 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.347G>A (p.Arg116His)	single nucleotide variant	not specified [RCV004157064]	Chr3:50290211 [GRCh38] Chr3:50327642 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.671G>T (p.Ser224Ile)	single nucleotide variant	not specified [RCV004157246]	Chr3:50289555 [GRCh38] Chr3:50326986 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.311C>T (p.Ala104Val)	single nucleotide variant	not specified [RCV004113258]	Chr3:50290247 [GRCh38] Chr3:50327678 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.-141C>A	single nucleotide variant	not specified [RCV004128815]	Chr3:50292415 [GRCh38] Chr3:50329846 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.1213G>T (p.Ala405Ser)	single nucleotide variant	not specified [RCV004130858]	Chr3:50288444 [GRCh38] Chr3:50325875 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.-26C>T	single nucleotide variant	not specified [RCV004205154]	Chr3:50292300 [GRCh38] Chr3:50329731 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.179G>C (p.Gly60Ala)	single nucleotide variant	not specified [RCV004081769]	Chr3:50290472 [GRCh38] Chr3:50327903 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.-39G>A	single nucleotide variant	not specified [RCV004170802]	Chr3:50292313 [GRCh38] Chr3:50329744 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.641G>A (p.Arg214Gln)	single nucleotide variant	not specified [RCV004077913]	Chr3:50289585 [GRCh38] Chr3:50327016 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.835G>A (p.Ala279Thr)	single nucleotide variant	not specified [RCV004239309]	Chr3:50289305 [GRCh38] Chr3:50326736 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.1057G>A (p.Gly353Ser)	single nucleotide variant	not specified [RCV004263108]	Chr3:50288678 [GRCh38] Chr3:50326109 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.-11C>G	single nucleotide variant	not specified [RCV004253617]	Chr3:50292285 [GRCh38] Chr3:50329716 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.1238G>T (p.Arg413Leu)	single nucleotide variant	not specified [RCV004265794]	Chr3:50288419 [GRCh38] Chr3:50325850 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.980G>A (p.Arg327Gln)	single nucleotide variant	not specified [RCV004294843]	Chr3:50288843 [GRCh38] Chr3:50326274 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.147C>G (p.Ser49Arg)	single nucleotide variant	not specified [RCV004353203]	Chr3:50290591 [GRCh38] Chr3:50328022 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.644T>A (p.Phe215Tyr)	single nucleotide variant	not specified [RCV004355233]	Chr3:50289582 [GRCh38] Chr3:50327013 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.1303C>T (p.Arg435Trp)	single nucleotide variant	not specified [RCV004349942]	Chr3:50288217 [GRCh38] Chr3:50325648 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.790C>T (p.Arg264Trp)	single nucleotide variant	not specified [RCV004344678]	Chr3:50289350 [GRCh38] Chr3:50326781 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.1166T>C (p.Leu389Pro)	single nucleotide variant	not specified [RCV004334714]	Chr3:50288491 [GRCh38] Chr3:50325922 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.427G>A (p.Gly143Ser)	single nucleotide variant	not specified [RCV004337558]	Chr3:50290048 [GRCh38] Chr3:50327479 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.697G>A (p.Gly233Ser)	single nucleotide variant	not specified [RCV004358546]	Chr3:50289529 [GRCh38] Chr3:50326960 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.-122G>T	single nucleotide variant	not specified [RCV004400246]	Chr3:50292396 [GRCh38] Chr3:50329827 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.577G>C (p.Val193Leu)	single nucleotide variant	not specified [RCV004400248]	Chr3:50289732 [GRCh38] Chr3:50327163 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.38G>A (p.Gly13Asp)	single nucleotide variant	not specified [RCV004400242]	Chr3:50292237 [GRCh38] Chr3:50329668 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.-92T>C	single nucleotide variant	not specified [RCV004400240]	Chr3:50292366 [GRCh38] Chr3:50329797 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.898T>C (p.Tyr300His)	single nucleotide variant	not specified [RCV004400241]	Chr3:50288925 [GRCh38] Chr3:50326356 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.115G>A (p.Glu39Lys)	single nucleotide variant	not specified [RCV004400244]	Chr3:50290623 [GRCh38] Chr3:50328054 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.253A>G (p.Thr85Ala)	single nucleotide variant	not specified [RCV004400245]	Chr3:50290398 [GRCh38] Chr3:50327829 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.532G>T (p.Ala178Ser)	single nucleotide variant	not specified [RCV004400247]	Chr3:50289943 [GRCh38] Chr3:50327374 [GRCh37] Chr3:3p21.31	uncertain significance
NM_006764.5(IFRD2):c.640C>T (p.Arg214Trp)	single nucleotide variant	not specified [RCV004400249]	Chr3:50289586 [GRCh38] Chr3:50327017 [GRCh37] Chr3:3p21.31	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	5848
Count of miRNA genes:	1064
Interacting mature miRNAs:	1344
Transcripts:	ENST00000336089, ENST00000414734, ENST00000417626, ENST00000426499, ENST00000429673, ENST00000436390, ENST00000438296, ENST00000462001, ENST00000464258, ENST00000468737, ENST00000469855, ENST00000474556, ENST00000483071, ENST00000484043, ENST00000486322, ENST00000489569, ENST00000492387
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

RH80851

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	50,330,310 - 50,330,545	UniSTS	GRCh37
Build 36	3	50,305,314 - 50,305,549	RGD	NCBI36
Celera	3	50,303,141 - 50,303,376	RGD
Cytogenetic Map	3	p21.3	UniSTS
HuRef	3	50,386,053 - 50,386,288	UniSTS
GeneMap99-GB4 RH Map	3	160.47	UniSTS

RH76408

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	50,325,222 - 50,325,470	UniSTS	GRCh37
Build 36	3	50,300,226 - 50,300,474	RGD	NCBI36
Celera	3	50,298,054 - 50,298,302	RGD
Cytogenetic Map	3	p21.31	UniSTS
Cytogenetic Map	3	p21.3	UniSTS
HuRef	3	50,380,965 - 50,381,213	UniSTS

IFRD2_8768

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	50,324,938 - 50,325,634	UniSTS	GRCh37
Build 36	3	50,299,942 - 50,300,638	RGD	NCBI36
Celera	3	50,297,770 - 50,298,466	RGD
HuRef	3	50,380,681 - 50,381,377	UniSTS

SHGC-76999

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	50,325,317 - 50,325,501	UniSTS	GRCh37
Build 36	3	50,300,321 - 50,300,505	RGD	NCBI36
Celera	3	50,298,149 - 50,298,333	RGD
Cytogenetic Map	3	p21.31	UniSTS
Cytogenetic Map	3	p21.3	UniSTS
HuRef	3	50,381,060 - 50,381,244	UniSTS
TNG Radiation Hybrid Map	3	31325.0	UniSTS
GeneMap99-GB4 RH Map	3	162.74	UniSTS
NCBI RH Map	3	491.7	UniSTS

HYAL3__6618

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	50,330,223 - 50,330,935	UniSTS	GRCh37
Build 36	3	50,305,227 - 50,305,939	RGD	NCBI36
Celera	3	50,303,054 - 50,303,766	RGD
HuRef	3	50,385,966 - 50,386,678	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

visual system

adipose tissue

appendage

entire extraembryonic component

pharyngeal arch

High

Medium

2429

2259

1710

616

1290

458

4353

2118

1848

390

1445

1602

171

1203

2787

Low

732

661

1873

Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_006764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AI292274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK074763	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK097765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK309114	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC001327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC001676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC007265	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC007437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BI825477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BT019999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U09585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U73167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U90094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y12395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000414734 ⟹ ENSP00000413726

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,288,799 - 50,292,389 (-)	Ensembl

RefSeq Acc Id:

ENST00000417626 ⟹ ENSP00000402849

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,287,732 - 50,292,429 (-)	Ensembl

RefSeq Acc Id:

ENST00000426499 ⟹ ENSP00000408549

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,287,743 - 50,288,639 (-)	Ensembl

RefSeq Acc Id:

ENST00000436390 ⟹ ENSP00000392316

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,287,743 - 50,292,918 (-)	Ensembl

RefSeq Acc Id:

ENST00000438296 ⟹ ENSP00000415448

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,288,430 - 50,290,251 (-)	Ensembl

RefSeq Acc Id:

ENST00000462001

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,290,009 - 50,292,436 (-)	Ensembl

RefSeq Acc Id:

ENST00000464258

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,288,131 - 50,289,601 (-)	Ensembl

RefSeq Acc Id:

ENST00000468737

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,290,181 - 50,292,056 (-)	Ensembl

RefSeq Acc Id:

ENST00000469855

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,288,663 - 50,289,263 (-)	Ensembl

RefSeq Acc Id:

ENST00000474556

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,287,941 - 50,292,424 (-)	Ensembl

RefSeq Acc Id:

ENST00000483071

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,289,208 - 50,290,070 (-)	Ensembl

RefSeq Acc Id:

ENST00000484043

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,290,006 - 50,292,049 (-)	Ensembl

RefSeq Acc Id:

ENST00000486322

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,288,371 - 50,289,060 (-)	Ensembl

RefSeq Acc Id:

ENST00000489569

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,289,248 - 50,292,420 (-)	Ensembl

RefSeq Acc Id:

ENST00000492387

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	50,288,512 - 50,289,226 (-)	Ensembl

RefSeq Acc Id:

NM_006764 ⟹ NP_006755

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	50,287,732 - 50,292,429 (-)	NCBI
GRCh37	3	50,325,163 - 50,330,648 (-)	NCBI
Build 36	3	50,300,124 - 50,304,923 (-)	NCBI Archive
Celera	3	50,297,995 - 50,302,857 (-)	RGD
HuRef	3	50,380,906 - 50,385,769 (-)	ENTREZGENE
CHM1_1	3	50,277,469 - 50,282,332 (-)	NCBI
T2T-CHM13v2.0	3	50,317,089 - 50,321,785 (-)	NCBI

Sequence:

show sequence

AGGGCGGGGCGCCTCGCGAAGATGGTGGCGCGCGTGGCGTGTGGCTCCCGTCGTCTGGCCAAGT
CTCAGCGCAGCGCACCGGCCGGCGTCTCGTTGGCCTGGAGCCCACACCCACCGGGTCCCTGACC
CCGCGCCCCCCGCGCCCGGTTCCCGGCATGCCTCGCGCCCGTAAGGGCAACACGCTCCGGAAGG
GTGGTCAGCGCCGTGGAGGAGGTGCCCGGAGCAGTGCCCAAGCTGACTCGGGTTCCAGTGACGA
TGAGGCAGCCAGTGAGGCCCGCAGCACCGCCAGTGAATGCCCCAGCCTTCTCAGCACCACTGCA
GAGGACAGCCTTGGGGGGGATGTCGTGGATGAGCAGGGCCAGCAGGAAGACCTTGAGGAAAAGC
TGAAGGAGTATGTGGACTGTCTCACAGACAAGAGTGCCAAGACCCGGCAGGGTGCTCTTGAGAG
CCTGCGCCTGGCCCTAGCGTCCCGCCTACTCCCCGACTTCTTGCTGGAGCGCCGCCTCACGCTA
GCCGATGCCCTGGAAAAGTGCCTCAAGAAAGGGAAGGGCGAGGAACAAGCCCTGGCTGCTGCTG
TGCTAGGCCTGCTCTGCGTGCAGCTGGGCCCTGGACCTAAGGGTGAGGAGCTGTTTCACAGCCT
GCAGCCTCTGCTGGTCTCTGTGCTCAGTGACAGCACAGCTAGCCCTGCTGCCCGGCTCCACTGT
GCTTCTGCCCTTGGCCTGGGCTGCTACGTGGCTGCCGCTGACATCCAGGACCTGGTCTCTTGCC
TTGCCTGCTTAGAAAGTGTTTTCAGCCGGTTCTATGGCTTGGGGGGCAGCTCCACAAGTCCTGT
GGTTCCTGCCAGCCTGCACGGCCTGCTCTCTGCTGCCCTGCAGGCCTGGGCATTGCTGCTCACC
ATCTGCCCTAGCACCCAAATCAGCCACATCCTTGACAGGCAGCTGCCCCGGCTGCCCCAGCTCT
TGTCCAGTGAAAGTGTGAACCTGCGGATCGCTGCCGGTGAAACCATTGCACTGCTCTTTGAGCT
TGCCCGGGACCTTGAGGAGGAGTTTGTTTACGAGGACATGGAGGCCCTCTGCAGTGTCCTGCGC
ACTCTGGCCACTGACAGTAACAAGTACCGTGCCAAGGCTGATCGTCGGCGCCAGCGCTCTACTT
TCCGCGCCGTGCTGCACTCCGTGGAGGGCGGTGAATGCGAAGAAGAGATAGTGCGCTTCGGCTT
TGAGGTGCTCTACATGGACAGCTGGGCTCGGCACCGGATCTACGCTGCCTTCAAGGAAGTGCTG
GGTTCGGGCATGCACCACCACCTCCAGAACAATGAGCTACTCCGTGACATCTTTGGCCTGGGCC
CTGTGCTGTTGCTGGATGCCACTGCCCTGAAGGCCTGCAAGGTTCCACGCTTTGAGAAGCACCT
GTACAATGCTGCTGCCTTCAAAGCCCGGACCAAGGCTCGAAGCCGTGTGCGGGACAAGCGGGCA
GACATCCTGTGAAGCAGGACCTGCTGAAGAGGAGACTTTCTATGCCCTTGGTCCGTATTTTTAA
CAGAAGACAGTGCAACAACTGGTCTCCACCAGTATTTGTCACTTTATTTTTTTTAATGACAAAA
CCAAAAACAGACATGGGGTGGGTAGCTGGGGGCCCGGACACTTGGGACCCTGACCCCTTTGTCC
CTGCACTCAGCCCTGTGGCCCCTTCCTGTCCTGTCTCAGGCCAGGCTAAATATGTGCCTTCCTC
AGGGCTGTGGGGCAGGCACTAGGGGGCCTTTCCCTTCCTTTCCTTTCTCAGGCCTTGCTCCCCC
AGGATGACCCACTCTTAGGGGGGTGGTGGCATCTGGACAAATGCCACCACAGCAGGTGGGGTGG
CAAAGCTACCTGGAATGGATTTGTGTGCTGATTTTTAAGGATTATTACAGATAATTAAACAGAA
CGGTCAGCCTTCTGTGGTCTTAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_006755	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC02728	(Get FASTA)	NCBI Sequence Viewer
	AAC16924	(Get FASTA)	NCBI Sequence Viewer
	AAH01327	(Get FASTA)	NCBI Sequence Viewer
	AAH01676	(Get FASTA)	NCBI Sequence Viewer
	AAH07265	(Get FASTA)	NCBI Sequence Viewer
	AAH07437	(Get FASTA)	NCBI Sequence Viewer
	AAV38802	(Get FASTA)	NCBI Sequence Viewer
	BAG51999	(Get FASTA)	NCBI Sequence Viewer
	CAA73027	(Get FASTA)	NCBI Sequence Viewer
	EAW65069	(Get FASTA)	NCBI Sequence Viewer
	EAW65070	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000392316.1
	ENSP00000402849
	ENSP00000402849.4
	ENSP00000408549.1
	ENSP00000413726.1
	ENSP00000415448.1
GenBank Protein	Q12894	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_006755 ⟸ NM_006764

- UniProtKB:

Q9UJ88 (UniProtKB/Swiss-Prot), Q9BVB4 (UniProtKB/Swiss-Prot), Q12894 (UniProtKB/Swiss-Prot), A0A0R4J2F6 (UniProtKB/TrEMBL), B3KQD7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAWNSPSRRPVWQGGAPREDGGARGVWLPSSGQVSAQRTGRRLVGLEPTPTGSLTPRPPRPVPG
MPRARKGNTLRKGGQRRGGGARSSAQADSGSSDDEAASEARSTASECPSLLSTTAEDSLGGDVV
DEQGQQEDLEEKLKEYVDCLTDKSAKTRQGALESLRLALASRLLPDFLLERRLTLADALEKCLK
KGKGEEQALAAAVLGLLCVQLGPGPKGEELFHSLQPLLVSVLSDSTASPAARLHCASALGLGCY
VAAADIQDLVSCLACLESVFSRFYGLGGSSTSPVVPASLHGLLSAALQAWALLLTICPSTQISH
ILDRQLPRLPQLLSSESVNLRIAAGETIALLFELARDLEEEFVYEDMEALCSVLRTLATDSNKY
RAKADRRRQRSTFRAVLHSVEGGECEEEIVRFGFEVLYMDSWARHRIYAAFKEVLGSGMHHHLQ
NNELLRDIFGLGPVLLLDATALKACKVPRFEKHLYNAAAFKARTKARSRVRDKRADIL

hide sequence

RefSeq Acc Id:

ENSP00000415448 ⟸ ENST00000438296

RefSeq Acc Id:

ENSP00000408549 ⟸ ENST00000426499

RefSeq Acc Id:

ENSP00000413726 ⟸ ENST00000414734

RefSeq Acc Id:

ENSP00000402849 ⟸ ENST00000417626

RefSeq Acc Id:

ENSP00000392316 ⟸ ENST00000436390

Protein Domains

Interferon-related developmental regulator C- Interferon-related developmental regulator N-

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q12894-F1-model_v2	AlphaFold	Q12894	1-506	view protein structure

Promoters

RGD ID:

6864492

Promoter ID:

EPDNEW_H5410

Type:

initiation region

Name:

IFRD2_1

Description:

interferon related developmental regulator 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H5411

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	50,292,554 - 50,292,614	EPDNEW

RGD ID:

6864494

Promoter ID:

EPDNEW_H5411

Type:

initiation region

Name:

IFRD2_2

Description:

interferon related developmental regulator 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H5410

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	50,292,921 - 50,292,981	EPDNEW

RGD ID:

6801145

Promoter ID:

HG_KWN:45126

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, HeLa_S3, Lymphoblastoid, NB4

Transcripts:

OTTHUMT00000346751, OTTHUMT00000346752, OTTHUMT00000346754, OTTHUMT00000346755, OTTHUMT00000346756, OTTHUMT00000346757

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	3	50,301,081 - 50,303,162 (-)	MPROMDB

RGD ID:

6801142

Promoter ID:

HG_KWN:45127

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, HeLa_S3, Jurkat, K562, Lymphoblastoid, NB4

Transcripts:

OTTHUMT00000346662, OTTHUMT00000346663, OTTHUMT00000346747, OTTHUMT00000346748, OTTHUMT00000346749, OTTHUMT00000346750, OTTHUMT00000346758, UC003CZA.1, UC003CZB.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	3	50,304,231 - 50,306,027 (-)	MPROMDB

RGD ID:

6852918

Promoter ID:

EP74278

Type:

initiation region

Name:

HS_IFRD2

Description:

Interferon-related developmental regulator 2.

SO ACC ID:

SO:0000170

Source:

EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Mammalian gene collection (MGC) full-length cDNA cloning

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	3	50,305,356 - 50,305,416	EPD

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:5457	AgrOrtholog
COSMIC	IFRD2	COSMIC
Ensembl Genes	ENSG00000214706	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENST00000414734.5	UniProtKB/TrEMBL
	ENST00000417626	ENTREZGENE
	ENST00000417626.8	UniProtKB/Swiss-Prot
	ENST00000426499.5	UniProtKB/TrEMBL
	ENST00000436390.5	UniProtKB/Swiss-Prot
	ENST00000438296.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000214706	GTEx
HGNC ID	HGNC:5457	ENTREZGENE
Human Proteome Map	IFRD2	Human Proteome Map
InterPro	ARM-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ARM-type_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IFRD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Interferon-rel_develop_reg_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Interferon-rel_develop_reg_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:7866	UniProtKB/Swiss-Prot
NCBI Gene	7866	ENTREZGENE
OMIM	602725	OMIM
PANTHER	INTERFERON-RELATED DEVELOPMENTAL REGULATOR 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR12354	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	IFRD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IFRD_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA29692	PharmGKB
Superfamily-SCOP	SSF48371	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0R4J2F6	ENTREZGENE
	B3KQD7	ENTREZGENE, UniProtKB/TrEMBL
	F8WEI6_HUMAN	UniProtKB/TrEMBL
	H7C2Z4_HUMAN	UniProtKB/TrEMBL
	H7C444_HUMAN	UniProtKB/TrEMBL
	IFRD2_HUMAN	UniProtKB/Swiss-Prot, ENTREZGENE
	Q9BVB4	ENTREZGENE
	Q9UJ88	ENTREZGENE
UniProt Secondary	A0A0R4J2F6	UniProtKB/Swiss-Prot
	Q9BVB4	UniProtKB/Swiss-Prot
	Q9UJ88	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-30	IFRD2	interferon related developmental regulator 2		interferon-related developmental regulator 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar