CTDNEP1 (CTD nuclear envelope phosphatase 1) - Rat Genome Database

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Gene: CTDNEP1 (CTD nuclear envelope phosphatase 1) Homo sapiens
Analyze
Symbol: CTDNEP1
Name: CTD nuclear envelope phosphatase 1
RGD ID: 1320917
HGNC Page HGNC:19085
Description: Enables protein serine/threonine phosphatase activity. Involved in nuclear envelope organization; positive regulation of triglyceride biosynthetic process; and protein localization to nucleus. Located in endoplasmic reticulum membrane; lipid droplet; and nuclear membrane. Part of Nem1-Spo7 phosphatase complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C-terminal domain nuclear envelope phosphatase 1; DULLARD; dullard homolog; HSA011916; NET56; serine/threonine-protein phosphatase dullard
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: CTDNEP1P1   CTDNEP1P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,243,591 - 7,251,978 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,243,591 - 7,252,491 (-)EnsemblGRCh38hg38GRCh38
GRCh37177,146,910 - 7,155,297 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,087,882 - 7,095,983 (-)NCBINCBI36Build 36hg18NCBI36
Build 34177,087,882 - 7,095,983NCBI
Celera177,171,550 - 7,179,904 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,038,309 - 7,046,665 (-)NCBIHuRef
CHM1_1177,155,699 - 7,164,051 (-)NCBICHM1_1
T2T-CHM13v2.0177,144,513 - 7,152,901 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12083771   PMID:12477932   PMID:17141153   PMID:17157258   PMID:17420445   PMID:21413788   PMID:21873635   PMID:22134922   PMID:22658674   PMID:25944354   PMID:26186194   PMID:27880917  
PMID:28287811   PMID:28514442   PMID:28986522   PMID:29117863   PMID:31073040   PMID:31343991   PMID:32271860   PMID:32296183   PMID:32513696   PMID:33845483   PMID:33961781   PMID:34373451  
PMID:35271311   PMID:35748872   PMID:36765089  


Genomics

Comparative Map Data
CTDNEP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,243,591 - 7,251,978 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,243,591 - 7,252,491 (-)EnsemblGRCh38hg38GRCh38
GRCh37177,146,910 - 7,155,297 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,087,882 - 7,095,983 (-)NCBINCBI36Build 36hg18NCBI36
Build 34177,087,882 - 7,095,983NCBI
Celera177,171,550 - 7,179,904 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,038,309 - 7,046,665 (-)NCBIHuRef
CHM1_1177,155,699 - 7,164,051 (-)NCBICHM1_1
T2T-CHM13v2.0177,144,513 - 7,152,901 (-)NCBIT2T-CHM13v2.0
Ctdnep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,871,994 - 69,881,427 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,871,982 - 69,881,427 (+)EnsemblGRCm39 Ensembl
GRCm381169,981,168 - 69,990,601 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,981,156 - 69,990,601 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,794,670 - 69,804,103 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,797,363 - 69,806,796 (+)NCBIMGSCv36mm8
Celera1177,529,199 - 77,538,411 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.95NCBI
Ctdnep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,203,047 - 55,212,469 (+)NCBIGRCr8
mRatBN7.21054,704,367 - 54,713,781 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,704,148 - 54,713,781 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,367,054 - 59,375,976 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,855,632 - 58,864,556 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,362,911 - 54,371,834 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,590,822 - 56,600,235 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,591,292 - 56,600,232 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,335,955 - 56,345,354 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,826,157 - 56,835,292 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,842,478 - 56,850,339 (+)NCBI
Celera1053,858,610 - 53,867,366 (+)NCBICelera
Cytogenetic Map10q24NCBI
Ctdnep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,660,288 - 9,666,878 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,660,088 - 9,666,878 (+)NCBIChiLan1.0ChiLan1.0
CTDNEP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21914,836,234 - 14,843,933 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11716,802,238 - 16,809,937 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,273,460 - 7,281,158 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,260,803 - 7,269,300 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,260,803 - 7,269,003 (-)Ensemblpanpan1.1panPan2
CTDNEP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,211,185 - 32,216,921 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,211,343 - 32,216,698 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,349,309 - 32,355,232 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,316,636 - 32,322,560 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,316,636 - 32,322,345 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,281,920 - 32,287,841 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,240,947 - 32,246,869 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,417,900 - 32,423,821 (-)NCBIUU_Cfam_GSD_1.0
Ctdnep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,062,943 - 47,069,147 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595536,297 - 543,071 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595537,131 - 543,341 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTDNEP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,617,609 - 6,625,261 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,617,966 - 6,625,342 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,785,432 - 14,793,149 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctdnep1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247869,860,758 - 9,867,293 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247869,857,370 - 9,867,299 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CTDNEP1
2 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17p13.2-13.1(chr17:5732977-8038822)x1 copy number loss See cases [RCV000051043] Chr17:5732977..8038822 [GRCh38]
Chr17:5636297..7942140 [GRCh37]
Chr17:5577021..7882865 [NCBI36]
Chr17:17p13.2-13.1		 pathogenic
GRCh38/hg38 17p13.1(chr17:6958978-8335684)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052457]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052457]|See cases [RCV000052457] Chr17:6958978..8335684 [GRCh38]
Chr17:6862297..8239002 [GRCh37]
Chr17:6803021..8179727 [NCBI36]
Chr17:17p13.1		 pathogenic
GRCh38/hg38 17p13.2-13.1(chr17:6307904-8842949)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053407]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053407]|See cases [RCV000053407] Chr17:6307904..8842949 [GRCh38]
Chr17:6211224..8746266 [GRCh37]
Chr17:6151948..8686991 [NCBI36]
Chr17:17p13.2-13.1		 pathogenic
GRCh38/hg38 17p13.1(chr17:7210345-7496934)x1 copy number loss See cases [RCV000053425] Chr17:7210345..7496934 [GRCh38]
Chr17:7113664..7400253 [GRCh37]
Chr17:7054388..7340977 [NCBI36]
Chr17:17p13.1		 pathogenic
NM_001143775.1(CTDNEP1):c.587C>A (p.Pro196Gln) single nucleotide variant Malignant melanoma [RCV000063300] Chr17:7246028 [GRCh38]
Chr17:7149347 [GRCh37]
Chr17:7090071 [NCBI36]
Chr17:17p13.1		 not provided
GRCh38/hg38 17p13.1(chr17:6958978-7491129)x3 copy number gain See cases [RCV000133763] Chr17:6958978..7491129 [GRCh38]
Chr17:6862297..7394448 [GRCh37]
Chr17:6803021..7335172 [NCBI36]
Chr17:17p13.1		 uncertain significance
GRCh38/hg38 17p13.3-13.1(chr17:198748-7491129)x3 copy number gain See cases [RCV000134970] Chr17:198748..7491129 [GRCh38]
Chr17:50690..7394448 [GRCh37]
Chr17:48539..7335172 [NCBI36]
Chr17:17p13.3-13.1		 pathogenic
GRCh38/hg38 17p13.2-12(chr17:5732953-12095349)x3 copy number gain See cases [RCV000134851] Chr17:5732953..12095349 [GRCh38]
Chr17:5636273..11998666 [GRCh37]
Chr17:5576997..11939391 [NCBI36]
Chr17:17p13.2-12		 pathogenic
GRCh38/hg38 17p13.3-13.1(chr17:162016-7697012)x1 copy number loss See cases [RCV000138214] Chr17:162016..7697012 [GRCh38]
Chr17:45835..7600330 [GRCh37]
Chr17:11807..7541055 [NCBI36]
Chr17:17p13.3-13.1		 pathogenic
GRCh38/hg38 17p13.2-13.1(chr17:6361393-7750863)x3 copy number gain See cases [RCV000138220] Chr17:6361393..7750863 [GRCh38]
Chr17:6264713..7654181 [GRCh37]
Chr17:6205437..7594906 [NCBI36]
Chr17:17p13.2-13.1		 likely pathogenic
GRCh38/hg38 17p13.3-12(chr17:162016-12343901)x3 copy number gain See cases [RCV000138531] Chr17:162016..12343901 [GRCh38]
Chr17:45835..12247218 [GRCh37]
Chr17:11807..12187943 [NCBI36]
Chr17:17p13.3-12		 pathogenic
GRCh38/hg38 17p13.1(chr17:6891357-7264234)x3 copy number gain See cases [RCV000139216] Chr17:6891357..7264234 [GRCh38]
Chr17:6794676..7167553 [GRCh37]
Chr17:6735400..7108277 [NCBI36]
Chr17:17p13.1		 uncertain significance
GRCh38/hg38 17p13.3-12(chr17:150732-14764202)x3 copy number gain See cases [RCV000142236] Chr17:150732..14764202 [GRCh38]
Chr17:525..14667519 [GRCh37]
Chr17:525..14608244 [NCBI36]
Chr17:17p13.3-12		 pathogenic
GRCh37/hg19 17p13.1(chr17:7120452-7165252)x3 copy number gain Breast ductal adenocarcinoma [RCV000207224] Chr17:7120452..7165252 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7121580-7186623)x3 copy number gain Breast ductal adenocarcinoma [RCV000207305] Chr17:7121580..7186623 [GRCh37]
Chr17:17p13.1		 likely pathogenic|uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-12(chr17:525-15027737)x3 copy number gain See cases [RCV000511786] Chr17:525..15027737 [GRCh37]
Chr17:17p13.3-12		 pathogenic
GRCh37/hg19 17p13.1(chr17:6934163-8217978)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626431] Chr17:6934163..8217978 [GRCh37]
Chr17:17p13.1		 drug response
GRCh37/hg19 17p13.1(chr17:7094070-7414448)x1 copy number loss See cases [RCV000512276] Chr17:7094070..7414448 [GRCh37]
Chr17:17p13.1		 likely pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
NC_000017.10:g.7124585_7400253dup duplication Robin sequence [RCV000677112] Chr17:7124585..7400253 [GRCh37]
Chr17:17p13.1		 uncertain significance
Single allele duplication Isolated Pierre-Robin syndrome [RCV000677112] Chr17:7124585..7400253 [GRCh37]
Chr17:17p13.1		 likely pathogenic
GRCh37/hg19 17p13.3-12(chr17:525-11186432)x3 copy number gain not provided [RCV000683866] Chr17:525..11186432 [GRCh37]
Chr17:17p13.3-12		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.1(chr17:7013365-7265208)x1 copy number loss not provided [RCV000739389] Chr17:7013365..7265208 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:6826243-7311408)x3 copy number gain not provided [RCV000849961] Chr17:6826243..7311408 [GRCh37]
Chr17:17p13.1		 uncertain significance
NC_000017.10:g.(?_6589506)_(8151374_?)dup duplication Common variable immunodeficiency [RCV001338841]|Dyskeratosis congenita [RCV001031775] Chr17:6589506..8151374 [GRCh37]
Chr17:17p13.1		 uncertain significance
NC_000017.10:g.(?_7123304)_(7606804_?)del deletion Common variable immunodeficiency [RCV003107751] Chr17:7123304..7606804 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:6800893-7304696)x1 copy number loss not provided [RCV001006866] Chr17:6800893..7304696 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.1(chr17:6650649-8040151)x3 copy number gain not provided [RCV001259299] Chr17:6650649..8040151 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.1(chr17:7014481-7283233)x1 copy number loss not provided [RCV001259300] Chr17:7014481..7283233 [GRCh37]
Chr17:17p13.1		 pathogenic
NC_000017.10:g.(?_6328780)_(7606804_?)dup duplication Congenital myasthenic syndrome 2A [RCV003109217]|Very long chain acyl-CoA dehydrogenase deficiency [RCV003119078] Chr17:6328780..7606804 [GRCh37]
Chr17:17p13.2-13.1		 uncertain significance
NM_001143775.2(CTDNEP1):c.39C>G (p.Phe13Leu) single nucleotide variant not specified [RCV004298919] Chr17:7251258 [GRCh38]
Chr17:7154577 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7020054-8086290) copy number loss not specified [RCV002052585] Chr17:7020054..8086290 [GRCh37]
Chr17:17p13.1		 pathogenic
NC_000017.10:g.(?_7120455)_(8151423_?)del deletion Li-Fraumeni syndrome [RCV003111420] Chr17:7120455..8151423 [GRCh37]
Chr17:17p13.1		 pathogenic
NC_000017.10:g.(?_7123304)_(8193254_?)del deletion Very long chain acyl-CoA dehydrogenase deficiency [RCV003119081] Chr17:7123304..8193254 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.1(chr17:7043719-7193448)x3 copy number gain not provided [RCV002474897] Chr17:7043719..7193448 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7004894-7766789)x1 copy number loss not provided [RCV003222936] Chr17:7004894..7766789 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh38/hg38 17p13.3-12(chr17:165730-11404096)x3 copy number gain Chromosome 17p13.3 duplication syndrome [RCV003327726] Chr17:165730..11404096 [GRCh38]
Chr17:17p13.3-12		 pathogenic
GRCh37/hg19 17p13.1(chr17:7002380-7469251)x1 copy number loss not specified [RCV003987240] Chr17:7002380..7469251 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.3-11.2(chr17:525-21510992)x3 copy number gain not specified [RCV003987215] Chr17:525..21510992 [GRCh37]
Chr17:17p13.3-11.2		 pathogenic
NM_001143775.2(CTDNEP1):c.337C>T (p.His113Tyr) single nucleotide variant not specified [RCV004372896] Chr17:7246814 [GRCh38]
Chr17:7150133 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001143775.2(CTDNEP1):c.256C>T (p.Arg86Trp) single nucleotide variant not specified [RCV004372895] Chr17:7247096 [GRCh38]
Chr17:7150415 [GRCh37]
Chr17:17p13.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3781
Count of miRNA genes:788
Interacting mature miRNAs:953
Transcripts:ENST00000318988, ENST00000570380, ENST00000570385, ENST00000570484, ENST00000570828, ENST00000571409, ENST00000572043, ENST00000573600, ENST00000574205, ENST00000574322, ENST00000575783, ENST00000576613
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH79691  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37177,146,967 - 7,147,235UniSTSGRCh37
GRCh373113,605,155 - 113,605,422UniSTSGRCh37
Build 363115,087,845 - 115,088,112RGDNCBI36
Celera177,171,611 - 7,171,879UniSTS
Celera3112,013,581 - 112,013,848RGD
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map3q13.31UniSTS
HuRef177,038,370 - 7,038,638UniSTS
HuRef3110,979,765 - 110,980,032UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1
Medium 2439 2981 1720 619 1943 460 4357 2192 3734 417 1459 1613 175 1 1204 2788 6 2
Low 10 6 5 8 5 5 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000318988   ⟹   ENSP00000321732
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,243,839 - 7,251,961 (-)Ensembl
RefSeq Acc Id: ENST00000570380   ⟹   ENSP00000461567
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,246,254 - 7,251,330 (-)Ensembl
RefSeq Acc Id: ENST00000570385
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,246,034 - 7,246,678 (-)Ensembl
RefSeq Acc Id: ENST00000570484
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,244,141 - 7,244,838 (-)Ensembl
RefSeq Acc Id: ENST00000570828   ⟹   ENSP00000460527
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,243,591 - 7,247,339 (-)Ensembl
RefSeq Acc Id: ENST00000571409   ⟹   ENSP00000458408
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,246,356 - 7,252,474 (-)Ensembl
RefSeq Acc Id: ENST00000572043   ⟹   ENSP00000459866
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,244,039 - 7,252,491 (-)Ensembl
RefSeq Acc Id: ENST00000573600   ⟹   ENSP00000461749
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,243,618 - 7,252,081 (-)Ensembl
RefSeq Acc Id: ENST00000574205   ⟹   ENSP00000458758
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,243,650 - 7,251,682 (-)Ensembl
RefSeq Acc Id: ENST00000574322   ⟹   ENSP00000460683
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,243,591 - 7,251,734 (-)Ensembl
RefSeq Acc Id: ENST00000575783   ⟹   ENSP00000461122
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,244,555 - 7,252,054 (-)Ensembl
RefSeq Acc Id: ENST00000576613   ⟹   ENSP00000458763
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl177,244,232 - 7,251,286 (-)Ensembl
RefSeq Acc Id: NM_001143775   ⟹   NP_001137247
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,243,591 - 7,251,734 (-)NCBI
GRCh37177,146,906 - 7,155,259 (-)RGD
Celera177,171,550 - 7,179,904 (-)RGD
HuRef177,038,309 - 7,046,665 (-)RGD
CHM1_1177,155,699 - 7,163,788 (-)NCBI
T2T-CHM13v2.0177,144,513 - 7,152,657 (-)NCBI
Sequence:
RefSeq Acc Id: NM_015343   ⟹   NP_056158
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,243,591 - 7,251,978 (-)NCBI
GRCh37177,146,906 - 7,155,259 (-)RGD
Build 36177,087,882 - 7,095,983 (-)NCBI Archive
Celera177,171,550 - 7,179,904 (-)RGD
HuRef177,038,309 - 7,046,665 (-)RGD
CHM1_1177,155,699 - 7,164,051 (-)NCBI
T2T-CHM13v2.0177,144,513 - 7,152,901 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_056158   ⟸   NM_015343
- UniProtKB: D3DTN7 (UniProtKB/Swiss-Prot),   Q96GQ9 (UniProtKB/Swiss-Prot),   O95476 (UniProtKB/Swiss-Prot),   I3L4B2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001137247   ⟸   NM_001143775
- UniProtKB: D3DTN7 (UniProtKB/Swiss-Prot),   Q96GQ9 (UniProtKB/Swiss-Prot),   O95476 (UniProtKB/Swiss-Prot),   I3L4B2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000461567   ⟸   ENST00000570380
RefSeq Acc Id: ENSP00000460527   ⟸   ENST00000570828
RefSeq Acc Id: ENSP00000458408   ⟸   ENST00000571409
RefSeq Acc Id: ENSP00000459866   ⟸   ENST00000572043
RefSeq Acc Id: ENSP00000461749   ⟸   ENST00000573600
RefSeq Acc Id: ENSP00000460683   ⟸   ENST00000574322
RefSeq Acc Id: ENSP00000458758   ⟸   ENST00000574205
RefSeq Acc Id: ENSP00000461122   ⟸   ENST00000575783
RefSeq Acc Id: ENSP00000458763   ⟸   ENST00000576613
RefSeq Acc Id: ENSP00000321732   ⟸   ENST00000318988
Protein Domains
FCP1 homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O95476-F1-model_v2 AlphaFold O95476 1-244 view protein structure

Promoters
RGD ID:6793972
Promoter ID:HG_KWN:24857
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   Jurkat,   Lymphoblastoid
Transcripts:OTTHUMT00000220030,   UC002GFC.1,   UC002GFD.1,   UC002GFF.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36177,096,001 - 7,096,777 (-)MPROMDB
RGD ID:7233665
Promoter ID:EPDNEW_H22577
Type:initiation region
Name:CTDNEP1_2
Description:CTD nuclear envelope phosphatase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22578  EPDNEW_H22583  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,251,710 - 7,251,770EPDNEW
RGD ID:7233663
Promoter ID:EPDNEW_H22578
Type:initiation region
Name:CTDNEP1_1
Description:CTD nuclear envelope phosphatase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22577  EPDNEW_H22583  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38177,251,977 - 7,252,037EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:19085 AgrOrtholog
COSMIC CTDNEP1 COSMIC
Ensembl Genes ENSG00000175826 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000318988 ENTREZGENE
  ENST00000318988.10 UniProtKB/Swiss-Prot
  ENST00000570380.5 UniProtKB/TrEMBL
  ENST00000570828.5 UniProtKB/TrEMBL
  ENST00000571409.1 UniProtKB/TrEMBL
  ENST00000572043.5 UniProtKB/TrEMBL
  ENST00000573600.5 UniProtKB/Swiss-Prot
  ENST00000574205.5 UniProtKB/Swiss-Prot
  ENST00000574322 ENTREZGENE
  ENST00000574322.6 UniProtKB/Swiss-Prot
  ENST00000575783.5 UniProtKB/TrEMBL
  ENST00000576613.5 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1000 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000175826 GTEx
HGNC ID HGNC:19085 ENTREZGENE
Human Proteome Map CTDNEP1 Human Proteome Map
InterPro Dullard_phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FCP1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HAD-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HAD_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:23399 UniProtKB/Swiss-Prot
NCBI Gene 23399 ENTREZGENE
OMIM 610684 OMIM
PANTHER CTD NUCLEAR ENVELOPE PHOSPHATASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DULLARD PROTEIN PHOSPHATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NIF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134937999 PharmGKB
PROSITE FCP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CPDc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56784 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CNEP1_HUMAN UniProtKB/Swiss-Prot
  D3DTN7 ENTREZGENE
  I3L0X6_HUMAN UniProtKB/TrEMBL
  I3L1D9_HUMAN UniProtKB/TrEMBL
  I3L2R5_HUMAN UniProtKB/TrEMBL
  I3L3K5_HUMAN UniProtKB/TrEMBL
  I3L4B2 ENTREZGENE, UniProtKB/TrEMBL
  I3L4W0_HUMAN UniProtKB/TrEMBL
  O95476 ENTREZGENE
  Q96GQ9 ENTREZGENE
UniProt Secondary D3DTN7 UniProtKB/Swiss-Prot
  Q96GQ9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 CTDNEP1  CTD nuclear envelope phosphatase 1  DULLARD  dullard homolog (Xenopus laevis)  Symbol and/or name change 5135510 APPROVED