TMEM30B (transmembrane protein 30B) - Rat Genome Database

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Gene: TMEM30B (transmembrane protein 30B) Homo sapiens
Analyze
Symbol: TMEM30B
Name: transmembrane protein 30B
RGD ID: 1318678
HGNC Page HGNC:27254
Description: Enables aminophospholipid flippase activity. Involved in aminophospholipid transport and positive regulation of protein exit from endoplasmic reticulum. Located in phospholipid-translocating ATPase complex and plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CDC50B; cell cycle control protein 50B; MGC126775; P4-ATPase flippase complex beta subunit TMEM30B
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: TMEM30BP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381461,277,370 - 61,281,338 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1461,277,370 - 61,281,761 (-)EnsemblGRCh38hg38GRCh38
GRCh371461,744,088 - 61,748,056 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361460,813,841 - 60,818,283 (-)NCBINCBI36Build 36hg18NCBI36
Celera1441,794,372 - 41,798,814 (-)NCBICelera
Cytogenetic Map14q23.1NCBI
HuRef1441,907,447 - 41,911,901 (-)NCBIHuRef
CHM1_11461,683,484 - 61,687,926 (-)NCBICHM1_1
T2T-CHM13v2.01455,483,965 - 55,487,943 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
melanoma  (EXP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15375526   PMID:15489334   PMID:16344560   PMID:20510206   PMID:20685720   PMID:20947505   PMID:20961850   PMID:21873635   PMID:21914794   PMID:23251661  
PMID:28514442   PMID:32296183   PMID:33845483   PMID:33961781  


Genomics

Comparative Map Data
TMEM30B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381461,277,370 - 61,281,338 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1461,277,370 - 61,281,761 (-)EnsemblGRCh38hg38GRCh38
GRCh371461,744,088 - 61,748,056 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361460,813,841 - 60,818,283 (-)NCBINCBI36Build 36hg18NCBI36
Celera1441,794,372 - 41,798,814 (-)NCBICelera
Cytogenetic Map14q23.1NCBI
HuRef1441,907,447 - 41,911,901 (-)NCBIHuRef
CHM1_11461,683,484 - 61,687,926 (-)NCBICHM1_1
T2T-CHM13v2.01455,483,965 - 55,487,943 (-)NCBIT2T-CHM13v2.0
Tmem30b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391273,589,888 - 73,593,169 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1273,590,176 - 73,593,166 (-)EnsemblGRCm39 Ensembl
GRCm381273,543,114 - 73,546,395 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1273,543,402 - 73,546,392 (-)EnsemblGRCm38mm10GRCm38
MGSCv371274,644,101 - 74,647,382 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361274,461,952 - 74,465,233 (-)NCBIMGSCv36mm8
Celera1274,649,888 - 74,653,169 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1230.65NCBI
Tmem30b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8697,987,471 - 97,990,546 (-)NCBIGRCr8
mRatBN7.2692,251,626 - 92,254,702 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl692,249,790 - 92,254,842 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx692,641,002 - 92,644,082 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0692,940,531 - 92,943,611 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0692,368,389 - 92,371,469 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0696,439,607 - 96,442,682 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl696,439,607 - 96,442,682 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06105,870,491 - 105,873,566 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4696,029,115 - 96,032,190 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1696,033,815 - 96,035,593 (-)NCBI
Celera690,712,443 - 90,715,518 (-)NCBICelera
Cytogenetic Map6q24NCBI
Tmem30b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554668,426,735 - 8,427,793 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554668,426,706 - 8,430,851 (+)NCBIChiLan1.0ChiLan1.0
TMEM30B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21562,408,788 - 62,453,706 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11461,625,301 - 61,628,664 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01441,880,759 - 41,882,090 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11460,135,989 - 60,139,390 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1460,138,410 - 60,139,780 (-)Ensemblpanpan1.1panPan2
TMEM30B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha835,936,392 - 35,939,911 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0836,416,593 - 36,420,113 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl836,417,354 - 36,420,119 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1836,026,784 - 36,030,301 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0836,104,285 - 36,107,798 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0836,466,075 - 36,469,596 (-)NCBIUU_Cfam_GSD_1.0
Tmem30b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864068,798,945 - 68,802,382 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364955,391,319 - 5,392,380 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364955,390,078 - 5,392,726 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM30B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1190,170,034 - 190,171,095 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11190,161,201 - 190,171,726 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21211,526,140 - 211,529,424 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM30B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12438,444,590 - 38,452,847 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2438,444,681 - 38,445,736 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605326,704,685 - 26,716,131 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem30b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473439,876,628 - 39,877,686 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473439,876,577 - 39,880,009 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TMEM30B
19 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 14q23.1-23.3(chr14:59917051-66750803)x1 copy number loss See cases [RCV000050892] Chr14:59917051..66750803 [GRCh38]
Chr14:60383769..67217521 [GRCh37]
Chr14:59453522..66287274 [NCBI36]
Chr14:14q23.1-23.3		 pathogenic
GRCh38/hg38 14q22.3-23.3(chr14:57041036-67208231)x1 copy number loss See cases [RCV000051521] Chr14:57041036..67208231 [GRCh38]
Chr14:57507754..67674948 [GRCh37]
Chr14:56577507..66744701 [NCBI36]
Chr14:14q22.3-23.3		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q23.1-23.2(chr14:57653413-64093528)x1 copy number loss See cases [RCV000138348] Chr14:57653413..64093528 [GRCh38]
Chr14:58120131..64560246 [GRCh37]
Chr14:57189884..63629999 [NCBI36]
Chr14:14q23.1-23.2		 pathogenic
GRCh38/hg38 14q23.1(chr14:61139770-61309705)x1 copy number loss See cases [RCV000139838] Chr14:61139770..61309705 [GRCh38]
Chr14:61606488..61776423 [GRCh37]
Chr14:60676241..60846176 [NCBI36]
Chr14:14q23.1		 uncertain significance
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19794561-107234280)x3 copy number gain See cases [RCV000446256] Chr14:19794561..107234280 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:20511673-107285437) copy number gain See cases [RCV000512041] Chr14:20511673..107285437 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q23.1(chr14:61678546-61984823)x1 copy number loss See cases [RCV000511690] Chr14:61678546..61984823 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.532C>T (p.His178Tyr) single nucleotide variant not specified [RCV004333905] Chr14:61280616 [GRCh38]
Chr14:61747334 [GRCh37]
Chr14:14q23.1		 uncertain significance
GRCh37/hg19 14q11.1-32.33(chr14:19000422-107289053)x3 copy number gain not provided [RCV000738412] Chr14:19000422..107289053 [GRCh37]
Chr14:14q11.1-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19280733-107287663)x3 copy number gain not provided [RCV000738413] Chr14:19280733..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19327823-107287663)x3 copy number gain not provided [RCV000738414] Chr14:19327823..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
Single allele duplication not provided [RCV000844902] Chr14:61701451..62960957 [GRCh37]
Chr14:14q23.1-23.2		 not provided
GRCh37/hg19 14q23.1-23.2(chr14:61701451-62960957) copy number gain not provided [RCV001249389] Chr14:61701451..62960957 [GRCh37]
Chr14:14q23.1-23.2		 not provided
GRCh37/hg19 14q23.1-23.2(chr14:61126208-63517651)x3 copy number gain not provided [RCV000845699] Chr14:61126208..63517651 [GRCh37]
Chr14:14q23.1-23.2		 uncertain significance
NM_001017970.3(TMEM30B):c.551G>A (p.Gly184Glu) single nucleotide variant not specified [RCV004319367] Chr14:61280597 [GRCh38]
Chr14:61747315 [GRCh37]
Chr14:14q23.1		 uncertain significance
GRCh37/hg19 14q23.1-23.3(chr14:61409856-65742610)x3 copy number gain not provided [RCV001259780] Chr14:61409856..65742610 [GRCh37]
Chr14:14q23.1-23.3		 likely pathogenic
GRCh37/hg19 14q22.2-24.3(chr14:54654001-75828024)x3 copy number gain 14q22.2q24.3 duplication [RCV001506967] Chr14:54654001..75828024 [GRCh37]
Chr14:14q22.2-24.3		 likely pathogenic
GRCh37/hg19 14q13.3-32.33(chr14:37671058-106985955)x2 copy number gain See cases [RCV002286356] Chr14:37671058..106985955 [GRCh37]
Chr14:14q13.3-32.33		 pathogenic
GRCh37/hg19 14q22.3-23.2(chr14:57804997-63590203)x1 copy number loss not provided [RCV002472446] Chr14:57804997..63590203 [GRCh37]
Chr14:14q22.3-23.2		 likely pathogenic
NM_001017970.3(TMEM30B):c.773C>T (p.Ala258Val) single nucleotide variant not specified [RCV004235972] Chr14:61280375 [GRCh38]
Chr14:61747093 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.827C>T (p.Ala276Val) single nucleotide variant not specified [RCV004206220] Chr14:61280321 [GRCh38]
Chr14:61747039 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.446C>T (p.Pro149Leu) single nucleotide variant not specified [RCV004169742] Chr14:61280702 [GRCh38]
Chr14:61747420 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.146T>G (p.Leu49Arg) single nucleotide variant not specified [RCV004236952] Chr14:61281002 [GRCh38]
Chr14:61747720 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.538C>T (p.Arg180Cys) single nucleotide variant not specified [RCV004084594] Chr14:61280610 [GRCh38]
Chr14:61747328 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.124G>T (p.Ala42Ser) single nucleotide variant not specified [RCV004204713] Chr14:61281024 [GRCh38]
Chr14:61747742 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.190G>C (p.Glu64Gln) single nucleotide variant not specified [RCV004152305] Chr14:61280958 [GRCh38]
Chr14:61747676 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.782C>G (p.Thr261Arg) single nucleotide variant not specified [RCV004131732] Chr14:61280366 [GRCh38]
Chr14:61747084 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.283G>A (p.Ala95Thr) single nucleotide variant not specified [RCV004175489] Chr14:61280865 [GRCh38]
Chr14:61747583 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.1032C>A (p.Asp344Glu) single nucleotide variant not specified [RCV004193583] Chr14:61280116 [GRCh38]
Chr14:61746834 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.457A>T (p.Ser153Cys) single nucleotide variant not specified [RCV004273669] Chr14:61280691 [GRCh38]
Chr14:61747409 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.740A>G (p.Asn247Ser) single nucleotide variant not specified [RCV004349743] Chr14:61280408 [GRCh38]
Chr14:61747126 [GRCh37]
Chr14:14q23.1		 uncertain significance
GRCh37/hg19 14q11.2-23.1(chr14:20511673-61826023)x3 copy number gain not provided [RCV003485022] Chr14:20511673..61826023 [GRCh37]
Chr14:14q11.2-23.1		 pathogenic
GRCh37/hg19 14q23.1-32.33(chr14:58894502-107227240)x3 copy number gain not provided [RCV003485036] Chr14:58894502..107227240 [GRCh37]
Chr14:14q23.1-32.33		 pathogenic
GRCh37/hg19 14q22.3-24.1(chr14:57588965-68334517)x3 copy number gain not provided [RCV003485034] Chr14:57588965..68334517 [GRCh37]
Chr14:14q22.3-24.1		 likely pathogenic
GRCh37/hg19 14q22.3-23.2(chr14:55667390-64447598)x1 copy number loss not provided [RCV003483204] Chr14:55667390..64447598 [GRCh37]
Chr14:14q22.3-23.2		 pathogenic
NM_001017970.3(TMEM30B):c.806T>G (p.Ile269Ser) single nucleotide variant not specified [RCV004467787] Chr14:61280342 [GRCh38]
Chr14:61747060 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.19G>A (p.Ala7Thr) single nucleotide variant not specified [RCV004467778] Chr14:61281129 [GRCh38]
Chr14:61747847 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.637A>G (p.Asn213Asp) single nucleotide variant not specified [RCV004467784] Chr14:61280511 [GRCh38]
Chr14:61747229 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.679C>T (p.Pro227Ser) single nucleotide variant not specified [RCV004467785] Chr14:61280469 [GRCh38]
Chr14:61747187 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.334T>G (p.Tyr112Asp) single nucleotide variant not specified [RCV004467780] Chr14:61280814 [GRCh38]
Chr14:61747532 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.349T>C (p.Phe117Leu) single nucleotide variant not specified [RCV004467781] Chr14:61280799 [GRCh38]
Chr14:61747517 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.790A>G (p.Lys264Glu) single nucleotide variant not specified [RCV004467786] Chr14:61280358 [GRCh38]
Chr14:61747076 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.898A>C (p.Lys300Gln) single nucleotide variant not specified [RCV004467788] Chr14:61280250 [GRCh38]
Chr14:61746968 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.314A>G (p.Gln105Arg) single nucleotide variant not specified [RCV004467779] Chr14:61280834 [GRCh38]
Chr14:61747552 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.629C>T (p.Pro210Leu) single nucleotide variant not specified [RCV004467783] Chr14:61280519 [GRCh38]
Chr14:61747237 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.407T>G (p.Leu136Arg) single nucleotide variant not specified [RCV004467782] Chr14:61280741 [GRCh38]
Chr14:61747459 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.334T>C (p.Tyr112His) single nucleotide variant not specified [RCV004237973] Chr14:61280814 [GRCh38]
Chr14:61747532 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.892G>A (p.Gly298Ser) single nucleotide variant not specified [RCV004280532] Chr14:61280256 [GRCh38]
Chr14:61746974 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.844G>T (p.Ala282Ser) single nucleotide variant not specified [RCV004335609] Chr14:61280304 [GRCh38]
Chr14:61747022 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.398T>C (p.Leu133Pro) single nucleotide variant not specified [RCV004357401] Chr14:61280750 [GRCh38]
Chr14:61747468 [GRCh37]
Chr14:14q23.1		 uncertain significance
NM_001017970.3(TMEM30B):c.912C>A (p.Phe304Leu) single nucleotide variant not specified [RCV004357402] Chr14:61280236 [GRCh38]
Chr14:61746954 [GRCh37]
Chr14:14q23.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2300
Count of miRNA genes:915
Interacting mature miRNAs:1064
Transcripts:ENST00000355702, ENST00000554497, ENST00000555868, ENST00000557163
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
G31464  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371461,744,640 - 61,744,749UniSTSGRCh37
Build 361460,814,393 - 60,814,502RGDNCBI36
Celera1441,794,924 - 41,795,033RGD
Cytogenetic Map14q23.1UniSTS
HuRef1441,907,999 - 41,908,108UniSTS
RH91843  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371461,744,743 - 61,744,928UniSTSGRCh37
Build 361460,814,496 - 60,814,681RGDNCBI36
Celera1441,795,027 - 41,795,212RGD
Cytogenetic Map14q23.1UniSTS
HuRef1441,908,102 - 41,908,287UniSTS
GeneMap99-GB4 RH Map14142.12UniSTS
UniSTS:485699  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371461,746,731 - 61,747,911UniSTSGRCh37
Celera1441,797,015 - 41,798,195UniSTS
HuRef1441,910,102 - 41,911,282UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 812 1018 1074 257 111 101 2356 12 787 148 619 1293 168 191 1544 1
Low 1564 919 620 352 403 348 1699 1573 1089 209 785 237 3 1008 1017 2 2
Below cutoff 42 1015 17 8 889 9 242 568 1759 33 29 34 3 1 5 227 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000554497
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1461,280,803 - 61,281,761 (-)Ensembl
RefSeq Acc Id: ENST00000555868   ⟹   ENSP00000450842
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1461,277,370 - 61,281,338 (-)Ensembl
RefSeq Acc Id: ENST00000557163
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1461,279,872 - 61,281,476 (-)Ensembl
RefSeq Acc Id: NM_001017970   ⟹   NP_001017970
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381461,277,370 - 61,281,338 (-)NCBI
GRCh371461,744,088 - 61,748,530 (-)RGD
Build 361460,813,841 - 60,818,283 (-)NCBI Archive
Celera1441,794,372 - 41,798,814 (-)RGD
HuRef1441,907,447 - 41,911,901 (-)RGD
CHM1_11461,683,484 - 61,687,926 (-)NCBI
T2T-CHM13v2.01455,483,965 - 55,487,943 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001017970 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI01727 (Get FASTA)   NCBI Sequence Viewer  
  AAI13560 (Get FASTA)   NCBI Sequence Viewer  
  BAG52296 (Get FASTA)   NCBI Sequence Viewer  
  EAW80799 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000450842
  ENSP00000450842.1
GenBank Protein Q3MIR4 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001017970   ⟸   NM_001017970
- UniProtKB: B3KR84 (UniProtKB/Swiss-Prot),   Q14D00 (UniProtKB/Swiss-Prot),   Q3MIR4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000450842   ⟸   ENST00000555868

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3MIR4-F1-model_v2 AlphaFold Q3MIR4 1-351 view protein structure

Promoters
RGD ID:6791954
Promoter ID:HG_KWN:19525
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour
Transcripts:ENST00000355702,   UC010APR.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361460,817,111 - 60,817,762 (-)MPROMDB
RGD ID:7227799
Promoter ID:EPDNEW_H19645
Type:initiation region
Name:TMEM30B_1
Description:transmembrane protein 30B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381461,281,379 - 61,281,439EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:27254 AgrOrtholog
COSMIC TMEM30B COSMIC
Ensembl Genes ENSG00000182107 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000555868 ENTREZGENE
  ENST00000555868.2 UniProtKB/Swiss-Prot
GTEx ENSG00000182107 GTEx
HGNC ID HGNC:27254 ENTREZGENE
Human Proteome Map TMEM30B Human Proteome Map
InterPro CDC50/LEM3_fam UniProtKB/Swiss-Prot
KEGG Report hsa:161291 UniProtKB/Swiss-Prot
NCBI Gene 161291 ENTREZGENE
OMIM 611029 OMIM
PANTHER PTHR10926 UniProtKB/Swiss-Prot
  PTHR10926:SF19 UniProtKB/Swiss-Prot
Pfam CDC50 UniProtKB/Swiss-Prot
PharmGKB PA134993260 PharmGKB
PIRSF DUF284_TM_euk UniProtKB/Swiss-Prot
UniProt B3KR84 ENTREZGENE
  CC50B_HUMAN UniProtKB/Swiss-Prot
  Q14D00 ENTREZGENE
  Q3MIR4 ENTREZGENE
UniProt Secondary B3KR84 UniProtKB/Swiss-Prot
  Q14D00 UniProtKB/Swiss-Prot