RYBP (RING1 and YY1 binding protein) - Rat Genome Database

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Gene: RYBP (RING1 and YY1 binding protein) Homo sapiens
Analyze
Symbol: RYBP
Name: RING1 and YY1 binding protein
RGD ID: 1316054
HGNC Page HGNC:10480
Description: Enables nucleic acid binding activity. Involved in several processes, including chromatin remodeling; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; and positive regulation of DNA-templated transcription. Located in nucleoplasm. Part of PcG protein complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AAP1; APAP-1; apoptin-associating protein 1; death effector domain-associated factor; DED-associated factor; DEDAF; RING1 and YY1-binding protein; ring1 interactor RYBP; YEAF1; YY1 and E4TF1 associated factor 1; YY1 and E4TF1-associated factor 1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38372,374,597 - 72,446,623 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl372,371,825 - 72,446,621 (-)EnsemblGRCh38hg38GRCh38
GRCh37372,423,744 - 72,495,774 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36372,506,438 - 72,578,462 (-)NCBINCBI36Build 36hg18NCBI36
Build 34372,508,773 - 72,578,464NCBI
Celera372,354,609 - 72,427,714 (-)NCBICelera
Cytogenetic Map3p13NCBI
HuRef372,426,405 - 72,499,331 (-)NCBIHuRef
CHM1_1372,375,955 - 72,448,623 (-)NCBICHM1_1
T2T-CHM13v2.0372,416,169 - 72,500,475 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleoplasm  (IDA,IEA,TAS)
nucleus  (IBA,IDA,IEA)
PcG protein complex  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8943360   PMID:10369680   PMID:11171983   PMID:11395500   PMID:11953439   PMID:12411495   PMID:12477932   PMID:14691460   PMID:14765135   PMID:15489334   PMID:16189514   PMID:16943429  
PMID:17070805   PMID:18551146   PMID:19098711   PMID:19170609   PMID:19322201   PMID:20379614   PMID:20543098   PMID:20696397   PMID:20881960   PMID:21530438   PMID:21653829   PMID:21873635  
PMID:22046132   PMID:22325352   PMID:22723975   PMID:23395003   PMID:23455922   PMID:23563607   PMID:24457600   PMID:24855944   PMID:24981860   PMID:25277244   PMID:25344099   PMID:25416956  
PMID:25429064   PMID:25519132   PMID:25814554   PMID:26104682   PMID:26186194   PMID:26496610   PMID:26687479   PMID:27060496   PMID:27505670   PMID:27634302   PMID:27705803   PMID:27748911  
PMID:27989698   PMID:28028181   PMID:28111200   PMID:28369212   PMID:28514442   PMID:29028833   PMID:29117863   PMID:29220657   PMID:29320735   PMID:29509190   PMID:29665352   PMID:30040487  
PMID:30217970   PMID:30431689   PMID:30638661   PMID:30804502   PMID:31113915   PMID:31545279   PMID:32209426   PMID:32296183   PMID:32707033   PMID:32814053   PMID:33537835   PMID:33945888  
PMID:33961781   PMID:34133714   PMID:34316702   PMID:35140242   PMID:35271311   PMID:35831314   PMID:35908953   PMID:35933409   PMID:35944360   PMID:36233063   PMID:36736316   PMID:37272752  


Genomics

Comparative Map Data
RYBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38372,374,597 - 72,446,623 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl372,371,825 - 72,446,621 (-)EnsemblGRCh38hg38GRCh38
GRCh37372,423,744 - 72,495,774 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36372,506,438 - 72,578,462 (-)NCBINCBI36Build 36hg18NCBI36
Build 34372,508,773 - 72,578,464NCBI
Celera372,354,609 - 72,427,714 (-)NCBICelera
Cytogenetic Map3p13NCBI
HuRef372,426,405 - 72,499,331 (-)NCBIHuRef
CHM1_1372,375,955 - 72,448,623 (-)NCBICHM1_1
T2T-CHM13v2.0372,416,169 - 72,500,475 (-)NCBIT2T-CHM13v2.0
Rybp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396100,205,526 - 100,264,319 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6100,205,526 - 100,264,446 (-)EnsemblGRCm39 Ensembl
GRCm386100,228,565 - 100,287,358 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6100,228,565 - 100,287,485 (-)EnsemblGRCm38mm10GRCm38
MGSCv376100,178,559 - 100,237,352 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366100,194,028 - 100,252,821 (-)NCBIMGSCv36mm8
Celera6102,093,266 - 102,151,363 (-)NCBICelera
Cytogenetic Map6D3NCBI
cM Map646.62NCBI
Rybp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84134,432,663 - 134,484,732 (-)NCBIGRCr8
mRatBN7.24132,876,260 - 132,928,328 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4132,876,361 - 132,928,316 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4138,290,334 - 138,342,407 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04134,071,106 - 134,123,179 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04132,689,373 - 132,741,452 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04132,689,623 - 132,740,823 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4132,689,531 - 132,740,938 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04197,177,356 - 197,228,556 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44135,101,700 - 135,153,427 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14135,346,439 - 135,400,411 (-)NCBI
Celera4121,729,359 - 121,780,574 (-)NCBICelera
Cytogenetic Map4q34NCBI
Rybp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542115,728,580 - 15,803,150 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542115,728,778 - 15,803,150 (+)NCBIChiLan1.0ChiLan1.0
RYBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2272,330,724 - 72,404,552 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1372,335,512 - 72,409,340 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0372,315,494 - 72,389,328 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1374,244,030 - 74,319,460 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl374,247,807 - 74,318,398 (-)Ensemblpanpan1.1panPan2
RYBP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12019,650,936 - 19,732,987 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2019,615,426 - 19,729,474 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2019,631,461 - 19,711,420 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02019,688,765 - 19,768,997 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12019,375,120 - 19,455,272 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02019,717,116 - 19,793,847 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02019,789,496 - 19,869,686 (+)NCBIUU_Cfam_GSD_1.0
Rybp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049423,618,715 - 3,693,007 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366033,618,795 - 3,690,410 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366033,618,715 - 3,693,007 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RYBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1353,724,065 - 53,809,601 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11353,724,062 - 53,809,698 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21359,462,871 - 59,523,645 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RYBP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12233,327,516 - 33,397,463 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2233,331,290 - 33,397,362 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041133,371,297 - 133,441,346 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rybp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247736,899,927 - 6,993,526 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247736,899,927 - 6,993,434 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RYBP
8 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3p14.1-12.3(chr3:64761248-78410098)x1 copy number loss See cases [RCV000051512] Chr3:64761248..78410098 [GRCh38]
Chr3:64746924..78459248 [GRCh37]
Chr3:64721964..78541938 [NCBI36]
Chr3:3p14.1-12.3		 pathogenic
GRCh38/hg38 3p13-12.3(chr3:70296167-74865078)x1 copy number loss See cases [RCV000051513] Chr3:70296167..74865078 [GRCh38]
Chr3:70345318..74914229 [GRCh37]
Chr3:70428008..74996919 [NCBI36]
Chr3:3p13-12.3		 pathogenic
GRCh38/hg38 3p14.1-13(chr3:67391006-73414001)x1 copy number loss See cases [RCV000133821] Chr3:67391006..73414001 [GRCh38]
Chr3:67441430..73463152 [GRCh37]
Chr3:67524120..73545842 [NCBI36]
Chr3:3p14.1-13		 pathogenic
GRCh38/hg38 3p14.1-12.3(chr3:68328980-76764319)x3 copy number gain See cases [RCV000140215] Chr3:68328980..76764319 [GRCh38]
Chr3:68378130..76813470 [GRCh37]
Chr3:68460820..76896160 [NCBI36]
Chr3:3p14.1-12.3		 likely pathogenic|uncertain significance
GRCh38/hg38 3p14.3-11.1(chr3:57140424-90259960)x1 copy number loss See cases [RCV000139626] Chr3:57140424..90259960 [GRCh38]
Chr3:57174452..90309110 [GRCh37]
Chr3:57149492..90391800 [NCBI36]
Chr3:3p14.3-11.1		 pathogenic
GRCh38/hg38 3p13-12.3(chr3:71317346-74324671)x1 copy number loss See cases [RCV000142649] Chr3:71317346..74324671 [GRCh38]
Chr3:71366497..74373822 [GRCh37]
Chr3:71449187..74456512 [NCBI36]
Chr3:3p13-12.3		 pathogenic
GRCh37/hg19 3p13(chr3:72207527-72497713)x1 copy number loss See cases [RCV000448017] Chr3:72207527..72497713 [GRCh37]
Chr3:3p13		 likely benign
GRCh37/hg19 3p13-12.3(chr3:70127345-74508912)x3 copy number gain See cases [RCV000448203] Chr3:70127345..74508912 [GRCh37]
Chr3:3p13-12.3		 uncertain significance
GRCh37/hg19 3p13-12.3(chr3:70433832-77012164)x1 copy number loss See cases [RCV000512368] Chr3:70433832..77012164 [GRCh37]
Chr3:3p13-12.3		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p14.1-12.3(chr3:66133719-75076440)x1 copy number loss not provided [RCV000682270] Chr3:66133719..75076440 [GRCh37]
Chr3:3p14.1-12.3		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p13-12.3(chr3:70938608-74660846)x3 copy number gain not provided [RCV001259675] Chr3:70938608..74660846 [GRCh37]
Chr3:3p13-12.3		 uncertain significance
Single allele deletion See cases [RCV001374461] Chr3:68965654..72679568 [GRCh37]
Chr3:3p14.1-13		 pathogenic
GRCh37/hg19 3p13-q12.1(chr3:72488757-99614758)x3 copy number gain not provided [RCV002221455] Chr3:72488757..99614758 [GRCh37]
Chr3:3p13-q12.1		 likely pathogenic
GRCh37/hg19 3p13(chr3:70583776-72793789)x1 copy number loss not specified [RCV003986401] Chr3:70583776..72793789 [GRCh37]
Chr3:3p13		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2019
Count of miRNA genes:942
Interacting mature miRNAs:1109
Transcripts:ENST00000477973
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-36192  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,453,996 - 72,454,096UniSTSGRCh37
Build 36372,536,686 - 72,536,786RGDNCBI36
Celera372,384,858 - 72,384,958RGD
Cytogenetic Map3p13UniSTS
HuRef372,456,662 - 72,456,762UniSTS
GeneMap99-G3 RH Map32250.0UniSTS
SHGC-77078  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,426,126 - 72,426,350UniSTSGRCh37
Build 36372,508,816 - 72,509,040RGDNCBI36
Celera372,356,991 - 72,357,215RGD
Cytogenetic Map3p13UniSTS
HuRef372,428,786 - 72,429,010UniSTS
TNG Radiation Hybrid Map346153.0UniSTS
GeneMap99-GB4 RH Map3211.07UniSTS
HSC10B052  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,423,770 - 72,424,045UniSTSGRCh37
Build 36372,506,460 - 72,506,735RGDNCBI36
Celera372,354,635 - 72,354,910RGD
Cytogenetic Map3p13UniSTS
HuRef372,426,431 - 72,426,706UniSTS
Whitehead-YAC Contig Map3 UniSTS
RH119434  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,440,637 - 72,440,950UniSTSGRCh37
Build 36372,523,327 - 72,523,640RGDNCBI36
Celera372,371,503 - 72,371,816RGD
Cytogenetic Map3p13UniSTS
HuRef372,443,297 - 72,443,610UniSTS
TNG Radiation Hybrid Map346148.0UniSTS
SGC33951  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,470,441 - 72,470,541UniSTSGRCh37
Build 36372,553,131 - 72,553,231RGDNCBI36
Celera372,401,303 - 72,401,403RGD
Cytogenetic Map3p13UniSTS
HuRef372,473,097 - 72,473,197UniSTS
GeneMap99-GB4 RH Map3211.81UniSTS
Whitehead-RH Map3259.6UniSTS
Cda10b05  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,423,903 - 72,424,002UniSTSGRCh37
Build 36372,506,593 - 72,506,692RGDNCBI36
Celera372,354,768 - 72,354,867RGD
Cytogenetic Map3p13UniSTS
HuRef372,426,564 - 72,426,663UniSTS
GeneMap99-GB4 RH Map3211.97UniSTS
RH16326  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,446,460 - 72,446,638UniSTSGRCh37
Build 36372,529,150 - 72,529,328RGDNCBI36
Celera372,377,326 - 72,377,504RGD
Cytogenetic Map3p13UniSTS
HuRef372,449,121 - 72,449,299UniSTS
GeneMap99-GB4 RH Map3211.18UniSTS
SGC34284  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,426,585 - 72,426,734UniSTSGRCh37
Build 36372,509,275 - 72,509,424RGDNCBI36
Celera372,357,450 - 72,357,599RGD
Cytogenetic Map3p13UniSTS
HuRef372,429,245 - 72,429,394UniSTS
GeneMap99-GB4 RH Map3213.52UniSTS
Whitehead-RH Map3256.1UniSTS
STS-AA027856  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,427,116 - 72,427,212UniSTSGRCh37
Build 36372,509,806 - 72,509,902RGDNCBI36
Celera372,357,981 - 72,358,077RGD
Cytogenetic Map3p13UniSTS
HuRef372,429,776 - 72,429,872UniSTS
GeneMap99-GB4 RH Map3211.18UniSTS
G19717  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,423,836 - 72,424,004UniSTSGRCh37
Build 36372,506,526 - 72,506,694RGDNCBI36
Celera372,354,701 - 72,354,869RGD
Cytogenetic Map3p13UniSTS
HuRef372,426,497 - 72,426,665UniSTS
A001W26  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,423,836 - 72,424,004UniSTSGRCh37
Build 36372,506,526 - 72,506,694RGDNCBI36
Celera372,354,701 - 72,354,869RGD
Cytogenetic Map3p13UniSTS
HuRef372,426,497 - 72,426,665UniSTS
TNG Radiation Hybrid Map346109.0UniSTS
GeneMap99-GB4 RH Map3211.97UniSTS
SHGC-52585  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,424,586 - 72,424,812UniSTSGRCh37
Build 36372,507,276 - 72,507,502RGDNCBI36
Celera372,355,451 - 72,355,677RGD
Cytogenetic Map3p13UniSTS
HuRef372,427,247 - 72,427,473UniSTS
TNG Radiation Hybrid Map346163.0UniSTS
GeneMap99-G3 RH Map32250.0UniSTS
WI-11804  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37372,426,100 - 72,426,201UniSTSGRCh37
Build 36372,508,790 - 72,508,891RGDNCBI36
Celera372,356,965 - 72,357,066RGD
Cytogenetic Map3p13UniSTS
HuRef372,428,760 - 72,428,861UniSTS
GeneMap99-GB4 RH Map3211.81UniSTS
Whitehead-RH Map3259.6UniSTS
NCBI RH Map3574.2UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1871 1921 1061 270 1727 173 3275 805 2134 294 1412 1517 109 1052 1850 4
Low 567 1069 665 354 224 292 1082 1392 1600 125 48 96 64 1 152 938 2 2
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054345905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054345906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB029551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC104330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC255560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF085840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF179286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF227959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL049940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY228125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC036459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF939411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HF583910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000477973   ⟹   ENSP00000419494
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl372,371,825 - 72,446,621 (-)Ensembl
RefSeq Acc Id: ENST00000676660
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl372,374,502 - 72,380,630 (-)Ensembl
RefSeq Acc Id: ENST00000676841
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl372,376,950 - 72,379,197 (-)Ensembl
RefSeq Acc Id: ENST00000677329
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl372,374,502 - 72,380,359 (-)Ensembl
RefSeq Acc Id: NM_012234   ⟹   NP_036366
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38372,374,597 - 72,446,623 (-)NCBI
GRCh37372,423,744 - 72,495,774 (-)ENTREZGENE
Build 36372,506,438 - 72,578,462 (-)NCBI Archive
HuRef372,426,405 - 72,499,331 (-)ENTREZGENE
CHM1_1372,375,955 - 72,448,623 (-)NCBI
T2T-CHM13v2.0372,416,173 - 72,489,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054345905   ⟹   XP_054201880
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0372,416,169 - 72,488,011 (-)NCBI
RefSeq Acc Id: XM_054345906   ⟹   XP_054201881
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0372,416,169 - 72,500,475 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_036366   ⟸   NM_012234
- UniProtKB: Q9P2W5 (UniProtKB/Swiss-Prot),   Q9UMW4 (UniProtKB/Swiss-Prot),   Q8N488 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000419494   ⟸   ENST00000477973
RefSeq Acc Id: XP_054201881   ⟸   XM_054345906
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054201880   ⟸   XM_054345905
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8N488-F1-model_v2 AlphaFold Q8N488 1-228 view protein structure

Promoters
RGD ID:6864994
Promoter ID:EPDNEW_H5662
Type:initiation region
Name:RYBP_1
Description:RING1 and YY1 binding protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38372,446,902 - 72,446,962EPDNEW
RGD ID:6801612
Promoter ID:HG_KWN:45526
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000295859
Position:
Human AssemblyChrPosition (strand)Source
Build 36372,578,281 - 72,579,292 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:10480 AgrOrtholog
COSMIC RYBP COSMIC
Ensembl Genes ENSG00000163602 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000281766 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000477973 ENTREZGENE
  ENST00000477973.5 UniProtKB/Swiss-Prot
  ENST00000628983.2 UniProtKB/Swiss-Prot
  ENST00000643872.3 UniProtKB/Swiss-Prot
Gene3D-CATH Zinc finger, RanBP2-type UniProtKB/Swiss-Prot
GTEx ENSG00000163602 GTEx
  ENSG00000281766 GTEx
HGNC ID HGNC:10480 ENTREZGENE
Human Proteome Map RYBP Human Proteome Map
InterPro RYBP/YAF2 UniProtKB/Swiss-Prot
  YAF2_RYBP UniProtKB/Swiss-Prot
  Znf_RanBP2 UniProtKB/Swiss-Prot
  Znf_RanBP2_sf UniProtKB/Swiss-Prot
KEGG Report hsa:23429 UniProtKB/Swiss-Prot
NCBI Gene 23429 ENTREZGENE
OMIM 607535 OMIM
PANTHER PTHR12920 UniProtKB/Swiss-Prot
  RING1 AND YY1-BINDING PROTEIN UniProtKB/Swiss-Prot
Pfam YAF2_RYBP UniProtKB/Swiss-Prot
  zf-RanBP UniProtKB/Swiss-Prot
PharmGKB PA34893 PharmGKB
PROSITE ZF_RANBP2_1 UniProtKB/Swiss-Prot
  ZF_RANBP2_2 UniProtKB/Swiss-Prot
SMART ZnF_RBZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF90209 UniProtKB/Swiss-Prot
UniProt L8ECE1_HUMAN UniProtKB/TrEMBL
  Q8N488 ENTREZGENE
  Q9P2W5 ENTREZGENE
  Q9UMW4 ENTREZGENE
  RYBP_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q9P2W5 UniProtKB/Swiss-Prot
  Q9UMW4 UniProtKB/Swiss-Prot