ANAPC4 (anaphase promoting complex subunit 4) - Rat Genome Database

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Pathways
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Gene: ANAPC4 (anaphase promoting complex subunit 4) Homo sapiens
Analyze
Symbol: ANAPC4
Name: anaphase promoting complex subunit 4
RGD ID: 1315264
HGNC Page HGNC:19990
Description: Enables protein phosphatase binding activity. Involved in protein K11-linked ubiquitination. Located in nucleus. Part of anaphase-promoting complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: anaphase-promoting complex subunit 4; APC4; cyclosome subunit 4
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38425,377,263 - 25,418,498 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl425,377,263 - 25,418,498 (+)EnsemblGRCh38hg38GRCh38
GRCh37425,378,885 - 25,420,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36424,987,946 - 25,029,218 (+)NCBINCBI36Build 36hg18NCBI36
Build 34425,055,116 - 25,096,388NCBI
Celera425,827,551 - 25,868,815 (+)NCBICelera
Cytogenetic Map4p15.2NCBI
HuRef424,719,025 - 24,760,288 (+)NCBIHuRef
CHM1_1425,378,460 - 25,419,732 (+)NCBICHM1_1
T2T-CHM13v2.0425,359,068 - 25,400,297 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
anaphase-promoting complex  (IBA,IDA,IEA,IPI,NAS)
cytosol  (TAS)
nuclear periphery  (IBA,IEA)
nucleoplasm  (TAS)
nucleus  (IDA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:6180011   PMID:8889548   PMID:9469815   PMID:10318877   PMID:10500174   PMID:10548110   PMID:10793135   PMID:10922056   PMID:11076961   PMID:11285280   PMID:11340163   PMID:11535616  
PMID:11742988   PMID:12070128   PMID:12477932   PMID:12956947   PMID:14593737   PMID:14657031   PMID:14684825   PMID:14702039   PMID:15029244   PMID:15678131   PMID:16364912   PMID:16921029  
PMID:17554300   PMID:18445686   PMID:18471975   PMID:18485873   PMID:19490893   PMID:19531213   PMID:19535905   PMID:19826416   PMID:20360068   PMID:20686030   PMID:20733055   PMID:20966902  
PMID:21043528   PMID:21241890   PMID:21335556   PMID:21336306   PMID:21873635   PMID:21926987   PMID:22014574   PMID:22145905   PMID:22193957   PMID:22939629   PMID:22990118   PMID:23007648  
PMID:23007861   PMID:23078409   PMID:23160376   PMID:23288039   PMID:23443559   PMID:23667531   PMID:23979597   PMID:24151075   PMID:24163370   PMID:24464857   PMID:25043029   PMID:25306918  
PMID:25306923   PMID:25383541   PMID:25490258   PMID:25669885   PMID:25673878   PMID:25723520   PMID:25750436   PMID:25859049   PMID:26083744   PMID:26186194   PMID:26299517   PMID:26344197  
PMID:26496610   PMID:26673895   PMID:26687479   PMID:26811472   PMID:26960431   PMID:26986935   PMID:27097363   PMID:27114510   PMID:27120157   PMID:27939943   PMID:28404789   PMID:28514442  
PMID:28700943   PMID:28813667   PMID:29033132   PMID:29180619   PMID:29229926   PMID:29509190   PMID:29517484   PMID:29549242   PMID:29863498   PMID:30021884   PMID:31024071   PMID:31753913  
PMID:31911655   PMID:32076268   PMID:32152539   PMID:32572027   PMID:33306668   PMID:33705438   PMID:33916271   PMID:33961781   PMID:34079125   PMID:34244565   PMID:34591612   PMID:34595750  
PMID:34831298   PMID:35271311   PMID:35563538   PMID:35831314   PMID:35913887   PMID:35952650   PMID:36215168   PMID:36373674   PMID:36736316   PMID:36774506   PMID:37689310   PMID:37827155  
PMID:37866880  


Genomics

Comparative Map Data
ANAPC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38425,377,263 - 25,418,498 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl425,377,263 - 25,418,498 (+)EnsemblGRCh38hg38GRCh38
GRCh37425,378,885 - 25,420,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36424,987,946 - 25,029,218 (+)NCBINCBI36Build 36hg18NCBI36
Build 34425,055,116 - 25,096,388NCBI
Celera425,827,551 - 25,868,815 (+)NCBICelera
Cytogenetic Map4p15.2NCBI
HuRef424,719,025 - 24,760,288 (+)NCBIHuRef
CHM1_1425,378,460 - 25,419,732 (+)NCBICHM1_1
T2T-CHM13v2.0425,359,068 - 25,400,297 (+)NCBIT2T-CHM13v2.0
Anapc4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39552,991,477 - 53,024,076 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl552,991,354 - 53,025,139 (+)EnsemblGRCm39 Ensembl
GRCm38552,834,135 - 52,866,734 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl552,834,012 - 52,867,797 (+)EnsemblGRCm38mm10GRCm38
MGSCv37553,225,374 - 53,257,973 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36553,122,383 - 53,154,982 (+)NCBIMGSCv36mm8
Celera550,211,245 - 50,243,925 (+)NCBICelera
Cytogenetic Map5C1NCBI
cM Map528.81NCBI
Anapc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81462,338,798 - 62,370,572 (-)NCBIGRCr8
mRatBN7.21458,125,995 - 58,159,253 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1458,125,995 - 58,157,770 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1462,531,803 - 62,563,517 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01463,845,907 - 63,877,674 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01460,242,664 - 60,274,431 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01460,471,962 - 60,503,803 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1460,471,962 - 60,503,803 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01460,589,356 - 60,621,597 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41462,879,772 - 62,911,465 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11462,882,490 - 62,913,803 (-)NCBI
Celera1457,225,366 - 57,257,057 (-)NCBICelera
Cytogenetic Map14q11NCBI
Anapc4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544319,620,480 - 19,653,200 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544319,620,480 - 19,653,179 (-)NCBIChiLan1.0ChiLan1.0
ANAPC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2325,628,089 - 25,667,796 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1425,821,150 - 25,860,847 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0419,777,750 - 19,817,459 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1425,061,715 - 25,101,386 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl425,061,930 - 25,101,260 (+)Ensemblpanpan1.1panPan2
ANAPC4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1384,878,686 - 84,914,876 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl384,878,693 - 84,914,882 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha387,391,671 - 87,427,899 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0385,851,958 - 85,888,197 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl385,851,964 - 85,888,044 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1384,985,804 - 85,022,014 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0385,091,368 - 85,127,587 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0385,476,904 - 85,513,179 (-)NCBIUU_Cfam_GSD_1.0
Anapc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528550,432,788 - 50,464,823 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364774,134,403 - 4,166,537 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364774,134,449 - 4,166,496 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANAPC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl819,301,248 - 19,341,478 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1819,301,253 - 19,341,463 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ANAPC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12724,947,516 - 24,989,331 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2724,946,681 - 24,989,208 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604771,462,966 - 71,505,053 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Anapc4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247557,013,763 - 7,047,424 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247557,013,769 - 7,047,292 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ANAPC4
26 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4p16.3-15.1(chr4:72555-28066309)x1 copy number loss See cases [RCV000051642] Chr4:72555..28066309 [GRCh38]
Chr4:72447..28067931 [GRCh37]
Chr4:62447..27677029 [NCBI36]
Chr4:4p16.3-15.1		 pathogenic
GRCh38/hg38 4p16.3-15.2(chr4:51519-26519788)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051752]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051752]|See cases [RCV000051752] Chr4:51519..26519788 [GRCh38]
Chr4:51413..26521410 [GRCh37]
Chr4:41413..26130508 [NCBI36]
Chr4:4p16.3-15.2		 pathogenic
GRCh38/hg38 4p16.3-15.1(chr4:72555-33130620)x3 copy number gain See cases [RCV000051753] Chr4:72555..33130620 [GRCh38]
Chr4:72447..33132242 [GRCh37]
Chr4:62447..32808637 [NCBI36]
Chr4:4p16.3-15.1		 pathogenic
GRCh38/hg38 4p16.3-14(chr4:85149-38700366)x3 copy number gain See cases [RCV000051757] Chr4:85149..38700366 [GRCh38]
Chr4:85040..38701987 [GRCh37]
Chr4:75040..38378382 [NCBI36]
Chr4:4p16.3-14		 pathogenic
GRCh38/hg38 4p15.31-15.2(chr4:21056309-26732162)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053263]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053263]|See cases [RCV000053263] Chr4:21056309..26732162 [GRCh38]
Chr4:21057932..26733784 [GRCh37]
Chr4:20667030..26342882 [NCBI36]
Chr4:4p15.31-15.2		 pathogenic
NM_013367.2(ANAPC4):c.832G>A (p.Glu278Lys) single nucleotide variant Malignant melanoma [RCV000066400] Chr4:25393847 [GRCh38]
Chr4:25395469 [GRCh37]
Chr4:25004567 [NCBI36]
Chr4:4p15.2		 not provided
NM_013367.2(ANAPC4):c.1543C>T (p.Pro515Ser) single nucleotide variant Malignant melanoma [RCV000060973] Chr4:25413662 [GRCh38]
Chr4:25415284 [GRCh37]
Chr4:25024382 [NCBI36]
Chr4:4p15.2		 not provided
NM_001286756.1(ANAPC4):c.1320+80C>G single nucleotide variant Lung cancer [RCV000094590] Chr4:25405702 [GRCh38]
Chr4:25407324 [GRCh37]
Chr4:4p15.2		 uncertain significance
GRCh38/hg38 4p16.3-14(chr4:72555-39477144)x3 copy number gain See cases [RCV000133677] Chr4:72555..39477144 [GRCh38]
Chr4:72447..39478764 [GRCh37]
Chr4:62447..39155159 [NCBI36]
Chr4:4p16.3-14		 pathogenic
GRCh38/hg38 4p15.2(chr4:23862000-27685546)x1 copy number loss See cases [RCV000135404] Chr4:23862000..27685546 [GRCh38]
Chr4:23863623..27687168 [GRCh37]
Chr4:23472721..27296266 [NCBI36]
Chr4:4p15.2		 pathogenic
GRCh38/hg38 4p15.32-15.1(chr4:16925022-32113076)x1 copy number loss See cases [RCV000135806] Chr4:16925022..32113076 [GRCh38]
Chr4:16926645..32114698 [GRCh37]
Chr4:16535743..31758596 [NCBI36]
Chr4:4p15.32-15.1		 pathogenic|likely pathogenic
GRCh38/hg38 4p16.3-12(chr4:36424-47491595)x3 copy number gain See cases [RCV000137261] Chr4:36424..47491595 [GRCh38]
Chr4:36424..47493612 [GRCh37]
Chr4:26424..47188369 [NCBI36]
Chr4:4p16.3-12		 pathogenic
NM_018176.3(LGI2):c.-473617_-693dup duplication Gestational diabetes mellitus uncontrolled [RCV000161338] Chr4:25031386..25504310 [GRCh38]
Chr4:25033008..25505932 [GRCh37]
Chr4:4p15.2		 not provided
GRCh37/hg19 4p16.3-15.1(chr4:71552-29006745)x1 copy number loss See cases [RCV000240003] Chr4:71552..29006745 [GRCh37]
Chr4:4p16.3-15.1		 pathogenic
GRCh37/hg19 4p16.3-11(chr4:12440-49064044)x3 copy number gain See cases [RCV000240562] Chr4:12440..49064044 [GRCh37]
Chr4:4p16.3-11		 pathogenic
GRCh37/hg19 4p16.3-11(chr4:68345-49089361)x3 copy number gain not specified [RCV003986479] Chr4:68345..49089361 [GRCh37]
Chr4:4p16.3-11		 pathogenic
GRCh37/hg19 4p15.2-15.1(chr4:23458442-29252060)x1 copy number loss See cases [RCV000240221] Chr4:23458442..29252060 [GRCh37]
Chr4:4p15.2-15.1		 pathogenic
GRCh37/hg19 4p16.3-11(chr4:68345-49089361)x3 copy number gain See cases [RCV002292704] Chr4:68345..49089361 [GRCh37]
Chr4:4p16.3-11		 pathogenic
GRCh37/hg19 4p16.3-11(chr4:68345-49093788)x3 copy number gain See cases [RCV000446451] Chr4:68345..49093788 [GRCh37]
Chr4:4p16.3-11		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p15.2-15.1(chr4:23790131-32302608)x1 copy number loss See cases [RCV000445756] Chr4:23790131..32302608 [GRCh37]
Chr4:4p15.2-15.1		 likely pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q13.1(chr4:68345-66440622)x3 copy number gain See cases [RCV000511193] Chr4:68345..66440622 [GRCh37]
Chr4:4p16.3-q13.1		 pathogenic
NM_013367.3(ANAPC4):c.1592A>G (p.Asn531Ser) single nucleotide variant not specified [RCV004307073] Chr4:25413711 [GRCh38]
Chr4:25415333 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.700T>A (p.Phe234Ile) single nucleotide variant not specified [RCV004330922] Chr4:25391010 [GRCh38]
Chr4:25392632 [GRCh37]
Chr4:4p15.2		 uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-11(chr4:68345-49089361)x3 copy number gain not provided [RCV000682363] Chr4:68345..49089361 [GRCh37]
Chr4:4p16.3-11		 pathogenic
GRCh37/hg19 4p16.3-15.1(chr4:4165334-33324781)x1 copy number loss not provided [RCV000682373] Chr4:4165334..33324781 [GRCh37]
Chr4:4p16.3-15.1		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-11(chr4:1356924-49659859)x3 copy number gain not provided [RCV000743201] Chr4:1356924..49659859 [GRCh37]
Chr4:4p16.3-11		 pathogenic
GRCh37/hg19 4p16.3-12(chr4:49450-46339070)x3 copy number gain not provided [RCV000743154] Chr4:49450..46339070 [GRCh37]
Chr4:4p16.3-12		 pathogenic
GRCh37/hg19 4p15.33-15.1(chr4:12778849-27760141) copy number loss not provided [RCV000767707] Chr4:12778849..27760141 [GRCh37]
Chr4:4p15.33-15.1		 pathogenic
GRCh37/hg19 4p15.31-15.1(chr4:20406475-29134345)x1 copy number loss not provided [RCV001005527] Chr4:20406475..29134345 [GRCh37]
Chr4:4p15.31-15.1		 pathogenic
NM_013367.3(ANAPC4):c.2107C>T (p.Arg703Cys) single nucleotide variant not specified [RCV004326530] Chr4:25417647 [GRCh38]
Chr4:25419269 [GRCh37]
Chr4:4p15.2		 uncertain significance
GRCh37/hg19 4p16.3-15.2(chr4:68345-27423424)x3 copy number gain not provided [RCV001005510] Chr4:68345..27423424 [GRCh37]
Chr4:4p16.3-15.2		 pathogenic
GRCh37/hg19 4p16.3-15.1(chr4:69671-29702595)x3 copy number gain not provided [RCV001537928] Chr4:69671..29702595 [GRCh37]
Chr4:4p16.3-15.1		 pathogenic
GRCh37/hg19 4p16.3-11(chr4:49450-49620898)x3 copy number gain See cases [RCV001194594] Chr4:49450..49620898 [GRCh37]
Chr4:4p16.3-11		 pathogenic
GRCh37/hg19 4p15.31-14(chr4:19892850-37325128) copy number loss not specified [RCV002053409] Chr4:19892850..37325128 [GRCh37]
Chr4:4p15.31-14		 pathogenic
GRCh37/hg19 4p15.2-15.1(chr4:23790131-32302608) copy number loss not specified [RCV002053411] Chr4:23790131..32302608 [GRCh37]
Chr4:4p15.2-15.1		 likely pathogenic
GRCh37/hg19 4p16.3-12(chr4:114784-47569569)x3 copy number gain FETAL DEMISE [RCV002282978] Chr4:114784..47569569 [GRCh37]
Chr4:4p16.3-12		 pathogenic
NM_013367.3(ANAPC4):c.1497C>G (p.Asp499Glu) single nucleotide variant not specified [RCV004322464] Chr4:25409763 [GRCh38]
Chr4:25411385 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.2330C>T (p.Ser777Leu) single nucleotide variant not specified [RCV004188385] Chr4:25418285 [GRCh38]
Chr4:25419907 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.749G>A (p.Arg250Gln) single nucleotide variant not specified [RCV004090290] Chr4:25392381 [GRCh38]
Chr4:25394003 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.2353C>A (p.Gln785Lys) single nucleotide variant not specified [RCV004194334] Chr4:25418308 [GRCh38]
Chr4:25419930 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1816G>C (p.Asp606His) single nucleotide variant not specified [RCV004118069] Chr4:25414690 [GRCh38]
Chr4:25416312 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1145A>G (p.Asp382Gly) single nucleotide variant not specified [RCV004089178] Chr4:25396747 [GRCh38]
Chr4:25398369 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.2298T>A (p.Asn766Lys) single nucleotide variant not specified [RCV004172877] Chr4:25418253 [GRCh38]
Chr4:25419875 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1874A>G (p.Tyr625Cys) single nucleotide variant not specified [RCV004164614] Chr4:25415513 [GRCh38]
Chr4:25417135 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1025C>A (p.Ser342Tyr) single nucleotide variant not specified [RCV004173671] Chr4:25394869 [GRCh38]
Chr4:25396491 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1016C>T (p.Ser339Leu) single nucleotide variant not specified [RCV004104956] Chr4:25394860 [GRCh38]
Chr4:25396482 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.254C>T (p.Ala85Val) single nucleotide variant not specified [RCV004180373] Chr4:25383279 [GRCh38]
Chr4:25384901 [GRCh37]
Chr4:4p15.2		 uncertain significance
GRCh38/hg38 4p15.33-14(chr4:11399082-38137335) copy number loss 4p partial monosomy syndrome [RCV003155905] Chr4:11399082..38137335 [GRCh38]
Chr4:4p15.33-14		 pathogenic
NM_013367.3(ANAPC4):c.308C>T (p.Ser103Phe) single nucleotide variant not specified [RCV004257002] Chr4:25383333 [GRCh38]
Chr4:25384955 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1700G>T (p.Arg567Leu) single nucleotide variant not specified [RCV004324420] Chr4:25414480 [GRCh38]
Chr4:25416102 [GRCh37]
Chr4:4p15.2		 uncertain significance
GRCh37/hg19 4p16.3-15.1(chr4:68345-34512694) copy number gain 4p16.3 microduplication syndrome [RCV003319592] Chr4:68345..34512694 [GRCh37]
Chr4:4p16.3-15.1		 pathogenic
GRCh38/hg38 4p16.3-11(chr4:1-49062177)x3 copy number gain Neurodevelopmental disorder [RCV003327611] Chr4:1..49062177 [GRCh38]
Chr4:4p16.3-11		 pathogenic
GRCh38/hg38 4p16.3-13(chr4:2904667-42963232)x3 copy number gain Neurodevelopmental disorder [RCV003327612] Chr4:2904667..42963232 [GRCh38]
Chr4:4p16.3-13		 pathogenic
GRCh38/hg38 4p16.3-q12(chr4:85624-57073230)x3 copy number gain Neurodevelopmental disorder [RCV003327613] Chr4:85624..57073230 [GRCh38]
Chr4:4p16.3-q12		 pathogenic
NM_013367.3(ANAPC4):c.1172C>T (p.Thr391Ile) single nucleotide variant not specified [RCV004351222] Chr4:25396857 [GRCh38]
Chr4:25398479 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.748C>T (p.Arg250Trp) single nucleotide variant not specified [RCV004356813] Chr4:25392380 [GRCh38]
Chr4:25394002 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1976G>A (p.Arg659His) single nucleotide variant not specified [RCV004347860] Chr4:25416499 [GRCh38]
Chr4:25418121 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1216G>A (p.Val406Ile) single nucleotide variant not specified [RCV004360670] Chr4:25402972 [GRCh38]
Chr4:25404594 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1876G>A (p.Ala626Thr) single nucleotide variant not specified [RCV004348938] Chr4:25415515 [GRCh38]
Chr4:25417137 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1315A>G (p.Lys439Glu) single nucleotide variant not specified [RCV004410184] Chr4:25405617 [GRCh38]
Chr4:25407239 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1370A>G (p.Asn457Ser) single nucleotide variant not specified [RCV004410187] Chr4:25406881 [GRCh38]
Chr4:25408503 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.1400G>A (p.Gly467Glu) single nucleotide variant not specified [RCV004410189] Chr4:25407222 [GRCh38]
Chr4:25408844 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.2221G>T (p.Val741Leu) single nucleotide variant not specified [RCV004410233] Chr4:25418176 [GRCh38]
Chr4:25419798 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.2289G>T (p.Glu763Asp) single nucleotide variant not specified [RCV004410234] Chr4:25418244 [GRCh38]
Chr4:25419866 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.485A>G (p.Asp162Gly) single nucleotide variant not specified [RCV004410242] Chr4:25388852 [GRCh38]
Chr4:25390474 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.680G>A (p.Gly227Asp) single nucleotide variant not specified [RCV004410248] Chr4:25390990 [GRCh38]
Chr4:25392612 [GRCh37]
Chr4:4p15.2		 uncertain significance
NM_013367.3(ANAPC4):c.808A>T (p.Thr270Ser) single nucleotide variant not specified [RCV004410262] Chr4:25393823 [GRCh38]
Chr4:25395445 [GRCh37]
Chr4:4p15.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1060
Count of miRNA genes:606
Interacting mature miRNAs:688
Transcripts:ENST00000315368, ENST00000503805, ENST00000504256, ENST00000505080, ENST00000505842, ENST00000505991, ENST00000506973, ENST00000507809, ENST00000507925, ENST00000510092, ENST00000515848
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-50273  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37425,419,934 - 25,420,031UniSTSGRCh37
Build 36425,029,032 - 25,029,129RGDNCBI36
Celera425,868,629 - 25,868,726RGD
Cytogenetic Map4p15.2UniSTS
HuRef424,760,102 - 24,760,199UniSTS
TNG Radiation Hybrid Map415776.0UniSTS
SHGC-24100  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37425,419,937 - 25,420,031UniSTSGRCh37
Build 36425,029,035 - 25,029,129RGDNCBI36
Celera425,868,632 - 25,868,726RGD
Cytogenetic Map4p15.2UniSTS
HuRef424,760,105 - 24,760,199UniSTS
TNG Radiation Hybrid Map415779.0UniSTS
SHGC-59815  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37425,419,867 - 25,419,977UniSTSGRCh37
Build 36425,028,965 - 25,029,075RGDNCBI36
Celera425,868,562 - 25,868,672RGD
Cytogenetic Map4p15.2UniSTS
HuRef424,760,035 - 24,760,145UniSTS
GeneMap99-GB4 RH Map4105.37UniSTS
RH92873  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37425,405,047 - 25,405,149UniSTSGRCh37
Build 36425,014,145 - 25,014,247RGDNCBI36
Celera425,853,743 - 25,853,845RGD
Cytogenetic Map4p15.2UniSTS
HuRef424,745,215 - 24,745,317UniSTS
SHGC-154840  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37425,407,551 - 25,407,842UniSTSGRCh37
Build 36425,016,649 - 25,016,940RGDNCBI36
Celera425,856,247 - 25,856,538RGD
Cytogenetic Map4p15.2UniSTS
HuRef424,747,719 - 24,748,010UniSTS
TNG Radiation Hybrid Map415773.0UniSTS
D4S2517E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37425,419,937 - 25,420,064UniSTSGRCh37
Build 36425,029,035 - 25,029,162RGDNCBI36
Celera425,868,632 - 25,868,759RGD
Cytogenetic Map4p15.2UniSTS
HuRef424,760,105 - 24,760,232UniSTS
Stanford-G3 RH Map41545.0UniSTS
NCBI RH Map4264.9UniSTS
GeneMap99-G3 RH Map41529.0UniSTS
D4S2679  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37425,419,907 - 25,420,094UniSTSGRCh37
Build 36425,029,005 - 25,029,192RGDNCBI36
Celera425,868,602 - 25,868,789RGD
Cytogenetic Map4p15.2UniSTS
HuRef424,760,075 - 24,760,262UniSTS
GeneMap99-GB4 RH Map4103.51UniSTS
Whitehead-RH Map4132.5UniSTS
Whitehead-YAC Contig Map4 UniSTS
NCBI RH Map4262.7UniSTS
ANAPC4  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37425,379,056 - 25,379,162UniSTSGRCh37
Celera425,827,763 - 25,827,869UniSTS
HuRef424,719,233 - 24,719,339UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2333 1841 1411 343 1279 187 3953 1483 3052 225 1344 1483 166 1201 2446 4
Low 105 1148 315 281 671 278 403 712 676 194 116 129 9 1 3 342 1 2
Below cutoff 1 1 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001286756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005248159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011513838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017008138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024454027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047450152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001741213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002959726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC108218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC110812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF191338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL353932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI546948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA312572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000315368   ⟹   ENSP00000318775
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,377,263 - 25,418,498 (+)Ensembl
RefSeq Acc Id: ENST00000503805
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,394,758 - 25,409,769 (+)Ensembl
RefSeq Acc Id: ENST00000504256
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,405,601 - 25,418,498 (+)Ensembl
RefSeq Acc Id: ENST00000505080   ⟹   ENSP00000426512
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,377,315 - 25,390,183 (+)Ensembl
RefSeq Acc Id: ENST00000505842
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,396,719 - 25,413,871 (+)Ensembl
RefSeq Acc Id: ENST00000505991   ⟹   ENSP00000421840
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,377,320 - 25,388,854 (+)Ensembl
RefSeq Acc Id: ENST00000506973
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,415,152 - 25,418,497 (+)Ensembl
RefSeq Acc Id: ENST00000507809
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,377,357 - 25,380,608 (+)Ensembl
RefSeq Acc Id: ENST00000507925
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,393,861 - 25,395,420 (+)Ensembl
RefSeq Acc Id: ENST00000510092   ⟹   ENSP00000426654
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,377,293 - 25,418,489 (+)Ensembl
RefSeq Acc Id: ENST00000515848
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl425,412,918 - 25,418,261 (+)Ensembl
RefSeq Acc Id: NM_001286756   ⟹   NP_001273685
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38425,377,263 - 25,418,498 (+)NCBI
HuRef424,719,025 - 24,760,288 (+)NCBI
CHM1_1425,378,460 - 25,419,732 (+)NCBI
T2T-CHM13v2.0425,359,068 - 25,400,297 (+)NCBI
Sequence:
RefSeq Acc Id: NM_013367   ⟹   NP_037499
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38425,377,263 - 25,418,498 (+)NCBI
GRCh37425,378,848 - 25,420,120 (+)ENTREZGENE
GRCh37425,378,848 - 25,420,120 (+)NCBI
Build 36424,987,946 - 25,029,218 (+)NCBI Archive
HuRef424,719,025 - 24,760,288 (+)ENTREZGENE
CHM1_1425,378,460 - 25,419,732 (+)NCBI
T2T-CHM13v2.0425,359,068 - 25,400,297 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005248159   ⟹   XP_005248216
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38425,394,830 - 25,418,498 (+)NCBI
GRCh37425,378,848 - 25,420,120 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011513838   ⟹   XP_011512140
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38425,380,374 - 25,418,498 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047450152   ⟹   XP_047306108
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38425,377,263 - 25,415,489 (+)NCBI
RefSeq Acc Id: XM_054349854   ⟹   XP_054205829
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0425,362,179 - 25,400,297 (+)NCBI
RefSeq Acc Id: XM_054349855   ⟹   XP_054205830
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0425,359,068 - 25,397,288 (+)NCBI
RefSeq Acc Id: XM_054349856   ⟹   XP_054205831
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0425,376,637 - 25,400,297 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_037499   ⟸   NM_013367
- Peptide Label: isoform 2
- UniProtKB: Q6PCC6 (UniProtKB/Swiss-Prot),   E9PCR4 (UniProtKB/Swiss-Prot),   A8K8H1 (UniProtKB/Swiss-Prot),   Q9NSH6 (UniProtKB/Swiss-Prot),   Q9UJX5 (UniProtKB/Swiss-Prot),   B3KN47 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005248216   ⟸   XM_005248159
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001273685   ⟸   NM_001286756
- Peptide Label: isoform 1
- UniProtKB: B3KN47 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011512140   ⟸   XM_011513838
- Peptide Label: isoform X1
- UniProtKB: B3KN47 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000421840   ⟸   ENST00000505991
RefSeq Acc Id: ENSP00000426512   ⟸   ENST00000505080
RefSeq Acc Id: ENSP00000426654   ⟸   ENST00000510092
RefSeq Acc Id: ENSP00000318775   ⟸   ENST00000315368
RefSeq Acc Id: XP_047306108   ⟸   XM_047450152
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054205830   ⟸   XM_054349855
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054205829   ⟸   XM_054349854
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054205831   ⟸   XM_054349856
- Peptide Label: isoform X3
Protein Domains
Anaphase-promoting complex subunit 4 long   Anaphase-promoting complex subunit 4-like WD40

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9UJX5-F1-model_v2 AlphaFold Q9UJX5 1-808 view protein structure

Promoters
RGD ID:6802041
Promoter ID:HG_KWN:47989
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000214986
Position:
Human AssemblyChrPosition (strand)Source
Build 36424,987,596 - 24,988,097 (+)MPROMDB
RGD ID:6867160
Promoter ID:EPDNEW_H6745
Type:initiation region
Name:ANAPC4_1
Description:anaphase promoting complex subunit 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H6746  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38425,377,272 - 25,377,332EPDNEW
RGD ID:6867162
Promoter ID:EPDNEW_H6746
Type:initiation region
Name:ANAPC4_2
Description:anaphase promoting complex subunit 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H6745  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38425,405,621 - 25,405,681EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:19990 AgrOrtholog
COSMIC ANAPC4 COSMIC
Ensembl Genes ENSG00000053900 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000315368 ENTREZGENE
  ENST00000315368.8 UniProtKB/Swiss-Prot
  ENST00000505080.1 UniProtKB/TrEMBL
  ENST00000505991.1 UniProtKB/TrEMBL
  ENST00000510092 ENTREZGENE
  ENST00000510092.5 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000053900 GTEx
HGNC ID HGNC:19990 ENTREZGENE
Human Proteome Map ANAPC4 Human Proteome Map
InterPro APC4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  APC4_long_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  APC4_metazoa UniProtKB/Swiss-Prot
  Apc4_WD40_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:29945 UniProtKB/Swiss-Prot
NCBI Gene 29945 ENTREZGENE
OMIM 606947 OMIM
PANTHER ANAPHASE-PROMOTING COMPLEX SUBUNIT 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13260 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ANAPC4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ANAPC4_WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134894250 PharmGKB
PIRSF APC4 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K8H1 ENTREZGENE
  APC4_HUMAN UniProtKB/Swiss-Prot
  B3KN47 ENTREZGENE, UniProtKB/TrEMBL
  D6RAP6_HUMAN UniProtKB/TrEMBL
  D6RFM7_HUMAN UniProtKB/TrEMBL
  E9PCR4 ENTREZGENE
  Q6PCC6 ENTREZGENE
  Q9NSH6 ENTREZGENE
  Q9UJX5 ENTREZGENE
UniProt Secondary A8K8H1 UniProtKB/Swiss-Prot
  E9PCR4 UniProtKB/Swiss-Prot
  Q6PCC6 UniProtKB/Swiss-Prot
  Q9NSH6 UniProtKB/Swiss-Prot