Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Pttg1ip (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PTTG1IP mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PTTG1IP mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of PTTG1IP mRNA] | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PTTG1IP mRNA | CTD | PMID:32109520 and PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTTG1IP mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PTTG1IP mRNA | CTD | PMID:21215274 | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bisphenol S results in increased expression of PTTG1IP protein | CTD | PMID:34186270 | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Omeprazole affects the expression of PTTG1IP mRNA | CTD | PMID:19483382 | 6-propyl-2-thiouracil | affects expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Propylthiouracil affects the expression of PTTG1IP mRNA | CTD | PMID:19483382 | 6-propyl-2-thiouracil | decreases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of PTTG1IP mRNA | CTD | PMID:30047161 | acrylamide | increases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of PTTG1IP mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PTTG1IP mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Tretinoin results in decreased expression of PTTG1IP mRNA | CTD | PMID:20488242 | amiodarone | affects expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Amiodarone affects the expression of PTTG1IP mRNA | CTD | PMID:19483382 | amitrole | decreases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of PTTG1IP mRNA | CTD | PMID:30047161 | antirheumatic drug | decreases expression | EXP | | 6480464 | Antirheumatic Agents results in decreased expression of PTTG1IP mRNA | CTD | PMID:24449571 | benzbromarone | affects expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Benzbromarone affects the expression of PTTG1IP mRNA | CTD | PMID:19483382 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of PTTG1IP promoter | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PTTG1IP mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PTTG1IP protein | CTD | PMID:34186270 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of PTTG1IP mRNA | CTD | PMID:30903817 | Bisphenol B | increases expression | EXP | | 6480464 | bisphenol B results in increased expression of PTTG1IP protein | CTD | PMID:34186270 | butanal | increases expression | EXP | | 6480464 | butyraldehyde results in increased expression of PTTG1IP mRNA | CTD | PMID:26079696 | cadmium dichloride | decreases methylation | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased methylation of PTTG1IP promoter | CTD | PMID:22457795 | cadmium dichloride | decreases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of PTTG1IP mRNA | CTD | PMID:33453195 | caffeine | increases phosphorylation | EXP | | 6480464 | Caffeine results in increased phosphorylation of PTTG1IP protein | CTD | PMID:35688186 | cantharidin | increases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Cantharidin results in increased expression of PTTG1IP mRNA | CTD | PMID:36907384 | carbon nanotube | increases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of PTTG1IP mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PTTG1IP gene] | CTD | PMID:28238834 | ciguatoxin CTX1B | affects expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Ciguatoxins affects the expression of PTTG1IP mRNA | CTD | PMID:18353800 | clobetasol | increases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Clobetasol results in increased expression of PTTG1IP mRNA | CTD | PMID:27462272 | clofibrate | affects expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Clofibrate affects the expression of PTTG1IP mRNA | CTD | PMID:19483382 | clofibric acid | affects expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Clofibric Acid affects the expression of PTTG1IP mRNA | CTD | PMID:17602206 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of PTTG1IP mRNA | CTD | PMID:19376846 | dexamethasone | increases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Dexamethasone results in increased expression of PTTG1IP mRNA | CTD | PMID:22733784 | disodium selenite | increases expression | EXP | | 6480464 | Sodium Selenite results in increased expression of PTTG1IP mRNA | CTD | PMID:18175754 | epoxiconazole | decreases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of PTTG1IP mRNA | CTD | PMID:35436446 | fenthion | decreases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Fenthion results in decreased expression of PTTG1IP mRNA | CTD | PMID:34813904 | folic acid | multiple interactions | ISO | Pttg1ip (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PTTG1IP mRNA | CTD | PMID:22206623 | hydrogen cyanide | increases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Hydrogen Cyanide results in increased expression of PTTG1IP mRNA | CTD | PMID:33914522 | L-ethionine | affects expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Ethionine affects the expression of PTTG1IP mRNA | CTD | PMID:19483382 | lipopolysaccharide | multiple interactions | EXP | | 6480464 | [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of PTTG1IP mRNA | CTD | PMID:35877022 | methidathion | affects expression | ISO | Pttg1ip (Mus musculus) | 6480464 | methidathion affects the expression of PTTG1IP mRNA | CTD | PMID:34813904 | methimazole | decreases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of PTTG1IP mRNA | CTD | PMID:30047161 | methoxychlor | affects methylation | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of PTTG1IP gene | CTD | PMID:35440735 | methylmercury chloride | decreases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | methylmercuric chloride results in decreased expression of PTTG1IP mRNA | CTD | PMID:19465457 | omeprazole | affects expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Omeprazole affects the expression of PTTG1IP mRNA | CTD | PMID:19483382 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of PTTG1IP mRNA | CTD | PMID:35430440 | phenobarbital | decreases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of PTTG1IP mRNA | CTD | PMID:23091169 and PMID:25270620 | pirinixic acid | affects expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | pirinixic acid affects the expression of PTTG1IP mRNA | CTD | PMID:19483382 | potassium cyanide | decreases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | Potassium Cyanide results in decreased expression of PTTG1IP mRNA | CTD | PMID:33914522 | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of PTTG1IP mRNA | CTD | PMID:23557933 | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide analog results in increased expression of PTTG1IP mRNA | CTD | PMID:25895662 | sodium arsenate | decreases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of PTTG1IP mRNA | CTD | PMID:21795629 | sodium arsenate | increases expression | ISO | Pttg1ip (Mus musculus) | 6480464 | sodium arsenate results in increased expression of PTTG1IP mRNA | CTD | PMID:21795629 | Soman | increases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Soman results in increased expression of PTTG1IP mRNA | CTD | PMID:19281266 | sulfadimethoxine | decreases expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of PTTG1IP mRNA | CTD | PMID:30047161 | thioacetamide | affects expression | ISO | Pttg1ip (Rattus norvegicus) | 6480464 | Thioacetamide affects the expression of PTTG1IP mRNA | CTD | PMID:19483382 | trichostatin A | affects expression | EXP | | 6480464 | trichostatin A affects the expression of PTTG1IP mRNA | CTD | PMID:28542535 | |