TSPAN4 (tetraspanin 4) - Rat Genome Database

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Gene: TSPAN4 (tetraspanin 4) Homo sapiens
Analyze
Symbol: TSPAN4
Name: tetraspanin 4
RGD ID: 1314069
HGNC Page HGNC:11859
Description: Enables antigen binding activity and integrin binding activity. Involved in protein-containing complex assembly. Located in plasma membrane and vesicle.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: NAG-2; NAG2; novel antigen 2; tetraspan; tetraspan TM4SF; tetraspanin-4; TM4SF7; transmembrane 4 superfamily member 7; TSPAN-4
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811842,852 - 867,111 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11842,812 - 867,116 (+)EnsemblGRCh38hg38GRCh38
GRCh3711842,852 - 867,111 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611832,824 - 857,116 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411832,823 - 857,109NCBI
Celera11880,283 - 934,195 (+)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11658,171 - 682,321 (+)NCBIHuRef
CHM1_111841,866 - 866,158 (+)NCBICHM1_1
T2T-CHM13v2.011894,229 - 918,529 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-methoxyethanol  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
acrolein  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (EXP)
all-trans-retinoic acid  (EXP)
alpha-pinene  (EXP)
amitrole  (ISO)
aristolochic acid A  (EXP)
Aroclor 1254  (ISO)
arsenous acid  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (EXP)
Benzo[k]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
C60 fullerene  (ISO)
carbon nanotube  (ISO)
carmustine  (EXP)
chrysene  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
Cuprizon  (ISO)
cyclosporin A  (EXP)
cytarabine  (EXP)
diarsenic trioxide  (EXP)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dioxygen  (ISO)
diuron  (EXP,ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
entinostat  (EXP)
epoxiconazole  (ISO)
fipronil  (ISO)
fulvestrant  (EXP)
glafenine  (ISO)
inulin  (ISO)
irinotecan  (ISO)
methamphetamine  (ISO)
methapyrilene  (EXP)
methimazole  (ISO)
methotrexate  (EXP,ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (EXP)
pirinixic acid  (EXP,ISO)
quercetin  (EXP)
rotenone  (ISO)
SB 431542  (EXP)
sulfadimethoxine  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
valproic acid  (EXP)
vancomycin  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
focal adhesion  (HDA)
membrane  (IEA)
migrasome  (ISO)
plasma membrane  (IBA,IDA)
vesicle  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9360996   PMID:9714763   PMID:10229664   PMID:10734060   PMID:10741407   PMID:11591653   PMID:11739647   PMID:12477932   PMID:14671302   PMID:14702039   PMID:15489334   PMID:16341674  
PMID:20237496   PMID:21423176   PMID:21516116   PMID:21873635   PMID:22236579   PMID:23383108   PMID:25416956   PMID:26439863   PMID:26760575   PMID:28298427   PMID:28611215   PMID:28986522  
PMID:31515488   PMID:32296183   PMID:34355505   PMID:34439793   PMID:36513632  


Genomics

Comparative Map Data
TSPAN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811842,852 - 867,111 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11842,812 - 867,116 (+)EnsemblGRCh38hg38GRCh38
GRCh3711842,852 - 867,111 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611832,824 - 857,116 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411832,823 - 857,109NCBI
Celera11880,283 - 934,195 (+)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11658,171 - 682,321 (+)NCBIHuRef
CHM1_111841,866 - 866,158 (+)NCBICHM1_1
T2T-CHM13v2.011894,229 - 918,529 (+)NCBIT2T-CHM13v2.0
Tspan4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,055,194 - 141,073,340 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7141,055,153 - 141,073,340 (+)EnsemblGRCm39 Ensembl
GRCm387141,475,236 - 141,493,427 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,475,240 - 141,493,427 (+)EnsemblGRCm38mm10GRCm38
MGSCv377148,661,139 - 148,679,321 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367141,326,560 - 141,344,742 (+)NCBIMGSCv36mm8
Celera7141,269,031 - 141,287,223 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.83NCBI
Tspan4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81206,001,731 - 206,021,414 (+)NCBIGRCr8
mRatBN7.21196,571,307 - 196,593,842 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,572,228 - 196,617,448 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1204,917,529 - 204,936,996 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,046,034 - 212,065,754 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01204,720,184 - 204,739,903 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01214,454,090 - 214,473,789 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,454,090 - 214,473,741 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,016,897 - 214,038,723 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,934,413 - 220,954,110 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,661,391 - 201,681,042 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1194,205,671 - 194,225,302 (+)NCBICelera
Cytogenetic Map1q41NCBI
Tspan4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,277,881 - 11,289,896 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,277,881 - 11,291,008 (-)NCBIChiLan1.0ChiLan1.0
TSPAN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v293,241,748 - 3,266,110 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,451,737 - 2,476,104 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011861,598 - 885,957 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111904,683 - 928,480 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11905,157 - 928,480 (+)Ensemblpanpan1.1panPan2
TSPAN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11845,220,763 - 45,224,981 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1845,203,620 - 45,224,674 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1843,869,557 - 43,891,669 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01845,867,525 - 45,889,748 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1845,875,251 - 45,889,721 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11845,332,357 - 45,354,370 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01844,897,103 - 44,919,232 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01845,635,240 - 45,657,457 (+)NCBIUU_Cfam_GSD_1.0
Tspan4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947602,005 - 618,275 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936888601,887 - 622,244 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936888601,834 - 618,092 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPAN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2534,341 - 550,697 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12532,087 - 550,706 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22123,615 - 142,270 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TSPAN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11649,316 - 673,317 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1650,407 - 673,763 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,738,857 - 97,762,755 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tspan4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476621,666,302 - 21,673,693 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476621,666,330 - 21,678,576 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TSPAN4
15 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11p15.5-15.4(chr11:196966-3377077)x3 copy number gain See cases [RCV000050947] Chr11:196966..3377077 [GRCh38]
Chr11:196966..3398307 [GRCh37]
Chr11:186966..3354883 [NCBI36]
Chr11:11p15.5-15.4		 pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196966-4435344)x3 copy number gain See cases [RCV000050927] Chr11:196966..4435344 [GRCh38]
Chr11:196966..4456574 [GRCh37]
Chr11:186966..4413150 [NCBI36]
Chr11:11p15.5-15.4		 pathogenic
GRCh38/hg38 11p15.5(chr11:758848-1998025)x1 copy number loss See cases [RCV000052645] Chr11:758848..1998025 [GRCh38]
Chr11:758848..2019255 [GRCh37]
Chr11:748848..1975831 [NCBI36]
Chr11:11p15.5		 pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:218365-3377077)x3 copy number gain See cases [RCV000053614] Chr11:218365..3377077 [GRCh38]
Chr11:218365..3398307 [GRCh37]
Chr11:208365..3354883 [NCBI36]
Chr11:11p15.5-15.4		 pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196966-3624139)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053592]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053592]|See cases [RCV000053592] Chr11:196966..3624139 [GRCh38]
Chr11:196966..3645369 [GRCh37]
Chr11:186966..3601945 [NCBI36]
Chr11:11p15.5-15.4		 pathogenic
GRCh38/hg38 11p15.5-13(chr11:202758-31726224)x3 copy number gain See cases [RCV000053613] Chr11:202758..31726224 [GRCh38]
Chr11:202758..31747772 [GRCh37]
Chr11:192758..31704348 [NCBI36]
Chr11:11p15.5-13		 pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:10701-5080415)x2 copy number gain See cases [RCV001310286] Chr11:10701..5080415 [GRCh37]
Chr11:11p15.5-15.4		 pathogenic
GRCh38/hg38 11p15.5-15.1(chr11:446754-18904742)x3 copy number gain See cases [RCV000133997] Chr11:446754..18904742 [GRCh38]
Chr11:446754..18926289 [GRCh37]
Chr11:436754..18882865 [NCBI36]
Chr11:11p15.5-15.1		 pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:61793-10727969)x3 copy number gain See cases [RCV000139987] Chr11:61793..10727969 [GRCh38]
Chr11:61793..10749516 [GRCh37]
Chr11:51793..10706092 [NCBI36]
Chr11:11p15.5-15.4		 pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196855-5321874)x3 copy number gain See cases [RCV000142890] Chr11:196855..5321874 [GRCh38]
Chr11:196855..5343104 [GRCh37]
Chr11:186855..5299680 [NCBI36]
Chr11:11p15.5-15.4		 pathogenic
GRCh38/hg38 11p15.5(chr11:196855-2116185)x3 copy number gain See cases [RCV000142923] Chr11:196855..2116185 [GRCh38]
Chr11:196855..2137415 [GRCh37]
Chr11:186855..2093991 [NCBI36]
Chr11:11p15.5		 pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:193187-5291338)x3 copy number gain See cases [RCV000446036] Chr11:193187..5291338 [GRCh37]
Chr11:11p15.5-15.4		 pathogenic
GRCh37/hg19 11p15.5(chr11:850336-1491561)x1 copy number loss Breast ductal adenocarcinoma [RCV000207296] Chr11:850336..1491561 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:230615-6644927)x3 copy number gain See cases [RCV000449417] Chr11:230615..6644927 [GRCh37]
Chr11:11p15.5-15.4		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-12(chr11:230615-37698540)x3 copy number gain See cases [RCV000511561] Chr11:230615..37698540 [GRCh37]
Chr11:11p15.5-12		 pathogenic
GRCh37/hg19 11p15.5-14.3(chr11:230615-25584362)x3 copy number gain See cases [RCV000512225] Chr11:230615..25584362 [GRCh37]
Chr11:11p15.5-14.3		 pathogenic
GRCh37/hg19 11p15.5-13(chr11:230615-31995219)x3 copy number gain See cases [RCV000512477] Chr11:230615..31995219 [GRCh37]
Chr11:11p15.5-13		 pathogenic
GRCh37/hg19 11p15.5-15.1(chr11:230615-17099213)x3 copy number gain not provided [RCV000683372] Chr11:230615..17099213 [GRCh37]
Chr11:11p15.5-15.1		 pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-9704511)x3 copy number gain not provided [RCV000683369] Chr11:230615..9704511 [GRCh37]
Chr11:11p15.5-15.4		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5(chr11:771034-850319)x3 copy number gain not provided [RCV000737364] Chr11:771034..850319 [GRCh37]
Chr11:11p15.5		 benign
GRCh37/hg19 11p15.5(chr11:800921-850319)x3 copy number gain not provided [RCV000737365] Chr11:800921..850319 [GRCh37]
Chr11:11p15.5		 benign
GRCh37/hg19 11p15.5(chr11:800921-1015021)x3 copy number gain not provided [RCV000737366] Chr11:800921..1015021 [GRCh37]
Chr11:11p15.5		 benign
GRCh37/hg19 11p15.5(chr11:821766-850319)x3 copy number gain not provided [RCV000737370] Chr11:821766..850319 [GRCh37]
Chr11:11p15.5		 benign
GRCh37/hg19 11p15.5(chr11:556531-927020)x3 copy number gain not provided [RCV000749890] Chr11:556531..927020 [GRCh37]
Chr11:11p15.5		 benign
NC_000011.9:g.(?_532616)_(2906985_?)dup duplication Neuronal ceroid lipofuscinosis [RCV001032557] Chr11:532616..2906985 [GRCh37]
Chr11:11p15.5-15.4		 uncertain significance
GRCh37/hg19 11p15.5-15.3(chr11:193146-12643136) copy number gain Silver-Russell syndrome 1 [RCV000767567] Chr11:193146..12643136 [GRCh37]
Chr11:11p15.5-15.3		 pathogenic
NM_003271.5(TSPAN4):c.202G>A (p.Gly68Ser) single nucleotide variant Inborn genetic diseases [RCV003243703] Chr11:862688 [GRCh38]
Chr11:862688 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5(chr11:831535-850367)x1 copy number loss not provided [RCV000994757] Chr11:831535..850367 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5(chr11:733608-986824)x3 copy number gain not provided [RCV000846573] Chr11:733608..986824 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5-13(chr11:235934-33826995)x3 copy number gain not provided [RCV001006372] Chr11:235934..33826995 [GRCh37]
Chr11:11p15.5-13		 pathogenic
NM_003271.5(TSPAN4):c.296C>T (p.Thr99Ile) single nucleotide variant Inborn genetic diseases [RCV003239959] Chr11:864477 [GRCh38]
Chr11:864477 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:230616-8250724)x3 copy number gain not provided [RCV002472435] Chr11:230616..8250724 [GRCh37]
Chr11:11p15.5-15.4		 pathogenic
NC_000011.9:g.(?_612625)_(2193840_?)dup duplication Immunodeficiency 39 [RCV001033372] Chr11:612625..2193840 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5(chr11:230615-1150353)x3 copy number gain not provided [RCV001259592] Chr11:230615..1150353 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:210300-8664358)x3 copy number gain Silver-Russell syndrome 1 [RCV001263222] Chr11:210300..8664358 [GRCh37]
Chr11:11p15.5-15.4		 pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-4851537)x3 copy number gain See cases [RCV001263059] Chr11:230615..4851537 [GRCh37]
Chr11:11p15.5-15.4		 pathogenic
NC_000011.9:g.(?_298501)_(4113028_?)dup duplication Early infantile epileptic encephalopathy with suppression bursts [RCV001316682] Chr11:298501..4113028 [GRCh37]
Chr11:11p15.5-15.4		 uncertain significance
NC_000011.9:g.(?_612625)_(2193840_?)dup duplication Autosomal recessive DOPA responsive dystonia [RCV001301561]|Immunodeficiency 39 [RCV001033372] Chr11:612625..2193840 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5(chr11:648556-1021236)x3 copy number gain not provided [RCV001834449] Chr11:648556..1021236 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:230615-5525355)x3 copy number gain not provided [RCV001825269] Chr11:230615..5525355 [GRCh37]
Chr11:11p15.5-15.4		 not provided
NC_000011.9:g.(?_721044)_(3988932_?)dup duplication not provided [RCV003113442] Chr11:721044..3988932 [GRCh37]
Chr11:11p15.5-15.4		 uncertain significance
NM_003271.5(TSPAN4):c.241T>C (p.Cys81Arg) single nucleotide variant Inborn genetic diseases [RCV003255161] Chr11:862727 [GRCh38]
Chr11:862727 [GRCh37]
Chr11:11p15.5		 uncertain significance
NC_000011.10:g.(499700_4999400)_(5279346_5279697)del deletion Thalassemia, gamma-delta-beta [RCV000015529] Chr11:4999400..5279346 [GRCh38]
Chr11:11p15.5-15.4		 pathogenic
GRCh37/hg19 11p15.5-14.2(chr11:230615-26881146)x3 copy number gain See cases [RCV002286351] Chr11:230615..26881146 [GRCh37]
Chr11:11p15.5-14.2		 pathogenic
GRCh37/hg19 11p15.5(chr11:461373-2157956)x4 copy number gain not provided [RCV002473945] Chr11:461373..2157956 [GRCh37]
Chr11:11p15.5		 pathogenic
NM_003271.5(TSPAN4):c.124G>A (p.Ala42Thr) single nucleotide variant Inborn genetic diseases [RCV002687415] Chr11:862610 [GRCh38]
Chr11:862610 [GRCh37]
Chr11:11p15.5		 uncertain significance
NM_003271.5(TSPAN4):c.638C>T (p.Ala213Val) single nucleotide variant Inborn genetic diseases [RCV002981493] Chr11:865991 [GRCh38]
Chr11:865991 [GRCh37]
Chr11:11p15.5		 uncertain significance
NM_003271.5(TSPAN4):c.667G>A (p.Ala223Thr) single nucleotide variant Inborn genetic diseases [RCV002931075] Chr11:866580 [GRCh38]
Chr11:866580 [GRCh37]
Chr11:11p15.5		 uncertain significance
NM_003271.5(TSPAN4):c.448G>A (p.Val150Ile) single nucleotide variant Inborn genetic diseases [RCV002713361] Chr11:865709 [GRCh38]
Chr11:865709 [GRCh37]
Chr11:11p15.5		 uncertain significance
NM_003271.5(TSPAN4):c.316G>A (p.Ala106Thr) single nucleotide variant Inborn genetic diseases [RCV002961607] Chr11:864497 [GRCh38]
Chr11:864497 [GRCh37]
Chr11:11p15.5		 uncertain significance
NM_003271.5(TSPAN4):c.470T>C (p.Phe157Ser) single nucleotide variant Inborn genetic diseases [RCV002648553] Chr11:865731 [GRCh38]
Chr11:865731 [GRCh37]
Chr11:11p15.5		 uncertain significance
NM_003271.5(TSPAN4):c.208G>A (p.Val70Met) single nucleotide variant Inborn genetic diseases [RCV003199509] Chr11:862694 [GRCh38]
Chr11:862694 [GRCh37]
Chr11:11p15.5		 uncertain significance
NM_003271.5(TSPAN4):c.215G>A (p.Cys72Tyr) single nucleotide variant Inborn genetic diseases [RCV003362131] Chr11:862701 [GRCh38]
Chr11:862701 [GRCh37]
Chr11:11p15.5		 uncertain significance
NM_003271.5(TSPAN4):c.644T>C (p.Val215Ala) single nucleotide variant Inborn genetic diseases [RCV003385414] Chr11:865997 [GRCh38]
Chr11:865997 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:192764-3362853)x3 copy number gain not provided [RCV003484828] Chr11:192764..3362853 [GRCh37]
Chr11:11p15.5-15.4		 pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-8821443)x3 copy number gain Russell-Silver syndrome [RCV003444025] Chr11:230615..8821443 [GRCh37]
Chr11:11p15.5-15.4		 pathogenic
GRCh37/hg19 11p15.5(chr11:743761-894572)x1 copy number loss not specified [RCV003986955] Chr11:743761..894572 [GRCh37]
Chr11:11p15.5		 uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:8198
Count of miRNA genes:993
Interacting mature miRNAs:1236
Transcripts:ENST00000346501, ENST00000397396, ENST00000397397, ENST00000397404, ENST00000397406, ENST00000397408, ENST00000397411, ENST00000409531, ENST00000409543, ENST00000464987, ENST00000468468, ENST00000494815, ENST00000524895, ENST00000525201, ENST00000525334, ENST00000526055, ENST00000527644, ENST00000529566, ENST00000530404, ENST00000532375
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH48177  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711839,829 - 840,000UniSTSGRCh37
Build 3611829,829 - 830,000RGDNCBI36
Celera11906,512 - 906,683RGD
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map11p15UniSTS
Cytogenetic Map1q32UniSTS
HuRef1173,082,023 - 173,083,126UniSTS
HuRef11655,176 - 655,347UniSTS
GeneMap99-GB4 RH Map1122.62UniSTS
NCBI RH Map1110.0UniSTS
RH47994  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711831,822 - 831,961UniSTSGRCh37
Build 3611821,822 - 821,961RGDNCBI36
Celera11898,458 - 898,597RGD
Cytogenetic Map11p15.5UniSTS
HuRef11647,089 - 647,228UniSTS
GeneMap99-GB4 RH Map1122.62UniSTS
NCBI RH Map1110.0UniSTS
RH41790  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711840,235 - 840,413UniSTSGRCh37
Build 3611830,235 - 830,413RGDNCBI36
Celera11906,918 - 907,096RGD
Cytogenetic Map11p15UniSTS
Cytogenetic Map11p15.5UniSTS
HuRef11655,582 - 655,760UniSTS
GeneMap99-GB4 RH Map1111.25UniSTS
NCBI RH Map1110.0UniSTS
D11S2243E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711812,571 - 812,791UniSTSGRCh37
Build 3611802,571 - 802,791RGDNCBI36
Celera11879,120 - 879,340RGD
Cytogenetic Map11p15.5UniSTS
HuRef11628,398 - 628,618UniSTS
GeneMap99-GB4 RH Map1120.53UniSTS
NCBI RH Map1110.0UniSTS
STS-W47645  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711866,917 - 867,099UniSTSGRCh37
Build 3611856,917 - 857,099RGDNCBI36
Celera11933,996 - 934,178RGD
Cytogenetic Map11p15.5UniSTS
HuRef11682,122 - 682,304UniSTS
GeneMap99-GB4 RH Map1122.82UniSTS
NCBI RH Map1110.0UniSTS
RH121967  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711840,212 - 840,373UniSTSGRCh37
Build 3611830,212 - 830,373RGDNCBI36
Celera11906,895 - 907,056RGD
Cytogenetic Map11p15UniSTS
Cytogenetic Map11p15.5UniSTS
HuRef11655,559 - 655,720UniSTS
A009K14  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711821,644 - 821,743UniSTSGRCh37
Build 3611811,644 - 811,743RGDNCBI36
Celera11888,297 - 888,396RGD
Cytogenetic Map11p15.5UniSTS
GeneMap99-GB4 RH Map1122.62UniSTS
NCBI RH Map1110.0UniSTS
G32609  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711821,644 - 821,743UniSTSGRCh37
Celera11888,297 - 888,396UniSTS
Cytogenetic Map11p15.5UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2187 2140 1506 428 626 276 3771 1485 1623 345 1394 1544 165 1204 2208 2
Low 245 840 215 196 1291 189 586 709 2088 74 61 67 7 1 580 2 2
Below cutoff 6 8 4 33 3 13 4 2 3 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001025235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001025236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001025237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001025238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001025239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005253102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005253104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011520336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011520337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011520338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011520339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011520340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011520341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF022813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF054841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK126456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL543667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP006623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW204812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY415329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF530006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG752017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI820547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM555783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM755435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ679002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT006776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR457108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000346501   ⟹   ENSP00000324304
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11847,197 - 866,776 (+)Ensembl
RefSeq Acc Id: ENST00000397396   ⟹   ENSP00000380551
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11842,824 - 867,116 (+)Ensembl
RefSeq Acc Id: ENST00000397397   ⟹   ENSP00000380552
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11842,852 - 867,111 (+)Ensembl
RefSeq Acc Id: ENST00000397404   ⟹   ENSP00000380553
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11844,446 - 867,116 (+)Ensembl
RefSeq Acc Id: ENST00000397406   ⟹   ENSP00000380554
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11844,081 - 867,116 (+)Ensembl
RefSeq Acc Id: ENST00000397408   ⟹   ENSP00000380555
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11842,941 - 867,116 (+)Ensembl
RefSeq Acc Id: ENST00000397411   ⟹   ENSP00000380558
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11842,812 - 866,817 (+)Ensembl
RefSeq Acc Id: ENST00000409531   ⟹   ENSP00000386899
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11848,810 - 867,111 (+)Ensembl
RefSeq Acc Id: ENST00000409543   ⟹   ENSP00000386513
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11844,117 - 866,857 (+)Ensembl
RefSeq Acc Id: ENST00000464987
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11847,197 - 867,109 (+)Ensembl
RefSeq Acc Id: ENST00000468468
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11862,297 - 867,109 (+)Ensembl
RefSeq Acc Id: ENST00000494815
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11863,272 - 867,111 (+)Ensembl
RefSeq Acc Id: ENST00000524895
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11847,197 - 864,653 (+)Ensembl
RefSeq Acc Id: ENST00000525201   ⟹   ENSP00000431943
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11844,153 - 866,676 (+)Ensembl
RefSeq Acc Id: ENST00000525334   ⟹   ENSP00000433980
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11843,339 - 865,753 (+)Ensembl
RefSeq Acc Id: ENST00000526055
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11847,197 - 862,834 (+)Ensembl
RefSeq Acc Id: ENST00000527644   ⟹   ENSP00000436260
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11849,816 - 867,111 (+)Ensembl
RefSeq Acc Id: ENST00000529566
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11862,345 - 865,825 (+)Ensembl
RefSeq Acc Id: ENST00000530404   ⟹   ENSP00000437266
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11843,315 - 862,741 (+)Ensembl
RefSeq Acc Id: ENST00000532375   ⟹   ENSP00000434818
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11847,197 - 865,942 (+)Ensembl
RefSeq Acc Id: NM_001025234   ⟹   NP_001020405
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811844,105 - 867,111 (+)NCBI
GRCh3711842,824 - 867,116 (+)RGD
Build 3611834,081 - 857,116 (+)NCBI Archive
Celera11880,283 - 934,195 (+)RGD
HuRef11658,171 - 682,321 (+)RGD
CHM1_111843,123 - 866,158 (+)NCBI
T2T-CHM13v2.011895,482 - 918,529 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001025235   ⟹   NP_001020406
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811842,941 - 867,111 (+)NCBI
GRCh3711842,824 - 867,116 (+)RGD
Build 3611832,941 - 857,116 (+)NCBI Archive
Celera11880,283 - 934,195 (+)RGD
HuRef11658,171 - 682,321 (+)RGD
CHM1_111841,983 - 866,158 (+)NCBI
T2T-CHM13v2.011894,318 - 918,529 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001025236   ⟹   NP_001020407
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811842,941 - 867,111 (+)NCBI
GRCh3711842,824 - 867,116 (+)RGD
Build 3611832,941 - 857,116 (+)NCBI Archive
Celera11880,283 - 934,195 (+)RGD
HuRef11658,171 - 682,321 (+)RGD
CHM1_111841,983 - 866,158 (+)NCBI
T2T-CHM13v2.011894,318 - 918,529 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001025237   ⟹   NP_001020408
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811844,414 - 867,111 (+)NCBI
GRCh3711842,824 - 867,116 (+)RGD
Build 3611834,446 - 857,116 (+)NCBI Archive
Celera11880,283 - 934,195 (+)RGD
HuRef11658,171 - 682,321 (+)RGD
CHM1_111843,488 - 866,158 (+)NCBI
T2T-CHM13v2.011895,791 - 918,529 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001025238   ⟹   NP_001020409
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811842,852 - 867,111 (+)NCBI
GRCh3711842,824 - 867,116 (+)RGD
Build 3611832,824 - 857,116 (+)NCBI Archive
Celera11880,283 - 934,195 (+)RGD
HuRef11658,171 - 682,321 (+)RGD
CHM1_111841,866 - 866,158 (+)NCBI
T2T-CHM13v2.011894,229 - 918,529 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001025239   ⟹   NP_001020410
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811842,852 - 867,111 (+)NCBI
GRCh3711842,824 - 867,116 (+)RGD
Build 3611832,824 - 857,116 (+)NCBI Archive
Celera11880,283 - 934,195 (+)RGD
HuRef11658,171 - 682,321 (+)RGD
CHM1_111841,866 - 866,158 (+)NCBI
T2T-CHM13v2.011894,229 - 918,529 (+)NCBI
Sequence:
RefSeq Acc Id: NM_003271   ⟹   NP_003262
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811842,852 - 867,111 (+)NCBI
GRCh3711842,824 - 867,116 (+)RGD
Build 3611832,824 - 857,116 (+)NCBI Archive
Celera11880,283 - 934,195 (+)RGD
HuRef11658,171 - 682,321 (+)RGD
CHM1_111841,866 - 866,158 (+)NCBI
T2T-CHM13v2.011894,229 - 918,529 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005253102   ⟹   XP_005253159
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811844,105 - 867,111 (+)NCBI
GRCh3711842,824 - 867,116 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011520337   ⟹   XP_011518639
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811844,105 - 867,111 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011520338   ⟹   XP_011518640
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811842,941 - 867,111 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011520339   ⟹   XP_011518641
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811844,105 - 867,111 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011520340   ⟹   XP_011518642
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811844,414 - 867,111 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011520341   ⟹   XP_011518643
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811842,941 - 867,111 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054369771   ⟹   XP_054225746
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.011894,515 - 918,529 (+)NCBI
RefSeq Acc Id: XM_054369772   ⟹   XP_054225747
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.011895,482 - 918,529 (+)NCBI
RefSeq Acc Id: XM_054369773   ⟹   XP_054225748
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.011894,318 - 918,529 (+)NCBI
RefSeq Acc Id: XM_054369774   ⟹   XP_054225749
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.011894,318 - 918,529 (+)NCBI
RefSeq Acc Id: XM_054369775   ⟹   XP_054225750
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.011895,791 - 918,529 (+)NCBI
RefSeq Acc Id: XM_054369776   ⟹   XP_054225751
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.011895,482 - 918,529 (+)NCBI
RefSeq Acc Id: XM_054369777   ⟹   XP_054225752
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.011895,482 - 918,529 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001020405 (Get FASTA)   NCBI Sequence Viewer  
  NP_001020406 (Get FASTA)   NCBI Sequence Viewer  
  NP_001020407 (Get FASTA)   NCBI Sequence Viewer  
  NP_001020408 (Get FASTA)   NCBI Sequence Viewer  
  NP_001020409 (Get FASTA)   NCBI Sequence Viewer  
  NP_001020410 (Get FASTA)   NCBI Sequence Viewer  
  NP_003262 (Get FASTA)   NCBI Sequence Viewer  
  XP_005253159 (Get FASTA)   NCBI Sequence Viewer  
  XP_011518639 (Get FASTA)   NCBI Sequence Viewer  
  XP_011518640 (Get FASTA)   NCBI Sequence Viewer  
  XP_011518641 (Get FASTA)   NCBI Sequence Viewer  
  XP_011518642 (Get FASTA)   NCBI Sequence Viewer  
  XP_011518643 (Get FASTA)   NCBI Sequence Viewer  
  XP_054225746 (Get FASTA)   NCBI Sequence Viewer  
  XP_054225747 (Get FASTA)   NCBI Sequence Viewer  
  XP_054225748 (Get FASTA)   NCBI Sequence Viewer  
  XP_054225749 (Get FASTA)   NCBI Sequence Viewer  
  XP_054225750 (Get FASTA)   NCBI Sequence Viewer  
  XP_054225751 (Get FASTA)   NCBI Sequence Viewer  
  XP_054225752 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC51864 (Get FASTA)   NCBI Sequence Viewer  
  AAC69717 (Get FASTA)   NCBI Sequence Viewer  
  AAH00389 (Get FASTA)   NCBI Sequence Viewer  
  AAH19314 (Get FASTA)   NCBI Sequence Viewer  
  AAH93031 (Get FASTA)   NCBI Sequence Viewer  
  AAP35422 (Get FASTA)   NCBI Sequence Viewer  
  BAF83778 (Get FASTA)   NCBI Sequence Viewer  
  CAG33389 (Get FASTA)   NCBI Sequence Viewer  
  EAX02409 (Get FASTA)   NCBI Sequence Viewer  
  EAX02410 (Get FASTA)   NCBI Sequence Viewer  
  EAX02411 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000324304.5
  ENSP00000380551
  ENSP00000380551.1
  ENSP00000380552
  ENSP00000380552.2
  ENSP00000380553
  ENSP00000380553.1
  ENSP00000380554
  ENSP00000380554.1
  ENSP00000380555
  ENSP00000380555.1
  ENSP00000380558
  ENSP00000380558.2
  ENSP00000386513
  ENSP00000386513.2
  ENSP00000386899.1
  ENSP00000431943
  ENSP00000431943.1
  ENSP00000433980.1
  ENSP00000434818.1
  ENSP00000436260.2
  ENSP00000437266.1
GenBank Protein O14817 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_003262   ⟸   NM_003271
- Peptide Label: isoform a
- UniProtKB: Q6IAP6 (UniProtKB/Swiss-Prot),   O14817 (UniProtKB/Swiss-Prot),   J3KQ42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020409   ⟸   NM_001025238
- Peptide Label: isoform a
- UniProtKB: Q6IAP6 (UniProtKB/Swiss-Prot),   O14817 (UniProtKB/Swiss-Prot),   J3KQ42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020410   ⟸   NM_001025239
- Peptide Label: isoform b
- UniProtKB: A8MVV6 (UniProtKB/TrEMBL),   B7WPM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020406   ⟸   NM_001025235
- Peptide Label: isoform a
- UniProtKB: Q6IAP6 (UniProtKB/Swiss-Prot),   O14817 (UniProtKB/Swiss-Prot),   J3KQ42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020407   ⟸   NM_001025236
- Peptide Label: isoform a
- UniProtKB: Q6IAP6 (UniProtKB/Swiss-Prot),   O14817 (UniProtKB/Swiss-Prot),   J3KQ42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020405   ⟸   NM_001025234
- Peptide Label: isoform a
- UniProtKB: Q6IAP6 (UniProtKB/Swiss-Prot),   O14817 (UniProtKB/Swiss-Prot),   J3KQ42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020408   ⟸   NM_001025237
- Peptide Label: isoform a
- UniProtKB: Q6IAP6 (UniProtKB/Swiss-Prot),   O14817 (UniProtKB/Swiss-Prot),   J3KQ42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005253159   ⟸   XM_005253102
- Peptide Label: isoform X1
- UniProtKB: Q6IAP6 (UniProtKB/Swiss-Prot),   O14817 (UniProtKB/Swiss-Prot),   J3KQ42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011518640   ⟸   XM_011520338
- Peptide Label: isoform X2
- UniProtKB: A8MVV6 (UniProtKB/TrEMBL),   B7WPM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011518643   ⟸   XM_011520341
- Peptide Label: isoform X2
- UniProtKB: A8MVV6 (UniProtKB/TrEMBL),   B7WPM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011518641   ⟸   XM_011520339
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011518639   ⟸   XM_011520337
- Peptide Label: isoform X2
- UniProtKB: A8MVV6 (UniProtKB/TrEMBL),   B7WPM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011518642   ⟸   XM_011520340
- Peptide Label: isoform X2
- UniProtKB: A8MVV6 (UniProtKB/TrEMBL),   B7WPM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000324304   ⟸   ENST00000346501
RefSeq Acc Id: ENSP00000437266   ⟸   ENST00000530404
RefSeq Acc Id: ENSP00000434818   ⟸   ENST00000532375
RefSeq Acc Id: ENSP00000433980   ⟸   ENST00000525334
RefSeq Acc Id: ENSP00000431943   ⟸   ENST00000525201
RefSeq Acc Id: ENSP00000386899   ⟸   ENST00000409531
RefSeq Acc Id: ENSP00000386513   ⟸   ENST00000409543
RefSeq Acc Id: ENSP00000436260   ⟸   ENST00000527644
RefSeq Acc Id: ENSP00000380552   ⟸   ENST00000397397
RefSeq Acc Id: ENSP00000380551   ⟸   ENST00000397396
RefSeq Acc Id: ENSP00000380555   ⟸   ENST00000397408
RefSeq Acc Id: ENSP00000380554   ⟸   ENST00000397406
RefSeq Acc Id: ENSP00000380553   ⟸   ENST00000397404
RefSeq Acc Id: ENSP00000380558   ⟸   ENST00000397411
RefSeq Acc Id: XP_054225749   ⟸   XM_054369774
- Peptide Label: isoform X2
- UniProtKB: B7WPM8 (UniProtKB/TrEMBL),   A8MVV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054225748   ⟸   XM_054369773
- Peptide Label: isoform X2
- UniProtKB: B7WPM8 (UniProtKB/TrEMBL),   A8MVV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054225746   ⟸   XM_054369771
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054225751   ⟸   XM_054369776
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054225752   ⟸   XM_054369777
- Peptide Label: isoform X2
- UniProtKB: B7WPM8 (UniProtKB/TrEMBL),   A8MVV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054225747   ⟸   XM_054369772
- Peptide Label: isoform X1
- UniProtKB: O14817 (UniProtKB/Swiss-Prot),   Q6IAP6 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054225750   ⟸   XM_054369775
- Peptide Label: isoform X2
- UniProtKB: B7WPM8 (UniProtKB/TrEMBL),   A8MVV6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O14817-F1-model_v2 AlphaFold O14817 1-238 view protein structure

Promoters
RGD ID:6789259
Promoter ID:HG_KWN:11876
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000397397,   NM_001025235,   NM_001025236,   NM_001025239,   NM_003271,   OTTHUMT00000257114,   OTTHUMT00000335355
Position:
Human AssemblyChrPosition (strand)Source
Build 3611832,326 - 832,826 (-)MPROMDB
RGD ID:6789486
Promoter ID:HG_KWN:11877
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   Lymphoblastoid,   NB4
Transcripts:ENST00000409543,   NM_001025234,   NM_001025237
Position:
Human AssemblyChrPosition (strand)Source
Build 3611833,266 - 834,037 (+)MPROMDB
RGD ID:6788882
Promoter ID:HG_KWN:11879
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell
Transcripts:ENST00000409531
Position:
Human AssemblyChrPosition (strand)Source
Build 3611838,236 - 838,736 (+)MPROMDB
RGD ID:7219243
Promoter ID:EPDNEW_H15366
Type:initiation region
Name:TSPAN4_1
Description:tetraspanin 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15367  EPDNEW_H15368  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811842,852 - 842,912EPDNEW
RGD ID:7219241
Promoter ID:EPDNEW_H15367
Type:initiation region
Name:TSPAN4_2
Description:tetraspanin 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15366  EPDNEW_H15368  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811844,147 - 844,207EPDNEW
RGD ID:7219245
Promoter ID:EPDNEW_H15368
Type:initiation region
Name:TSPAN4_3
Description:tetraspanin 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15367  EPDNEW_H15366  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811849,856 - 849,916EPDNEW
RGD ID:6789485
Promoter ID:HG_KWN:11882
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:NB4
Transcripts:OTTHUMT00000335352
Position:
Human AssemblyChrPosition (strand)Source
Build 3611851,946 - 852,446 (+)MPROMDB
RGD ID:6789487
Promoter ID:HG_KWN:11883
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000335353
Position:
Human AssemblyChrPosition (strand)Source
Build 3611852,386 - 854,437 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11859 AgrOrtholog
COSMIC TSPAN4 COSMIC
Ensembl Genes ENSG00000214063 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000346501.8 UniProtKB/TrEMBL
  ENST00000397396 ENTREZGENE
  ENST00000397396.5 UniProtKB/TrEMBL
  ENST00000397397 ENTREZGENE
  ENST00000397397.7 UniProtKB/Swiss-Prot
  ENST00000397404 ENTREZGENE
  ENST00000397404.5 UniProtKB/Swiss-Prot
  ENST00000397406 ENTREZGENE
  ENST00000397406.5 UniProtKB/Swiss-Prot
  ENST00000397408 ENTREZGENE
  ENST00000397408.5 UniProtKB/Swiss-Prot
  ENST00000397411 ENTREZGENE
  ENST00000397411.6 UniProtKB/Swiss-Prot
  ENST00000409531.5 UniProtKB/TrEMBL
  ENST00000409543 ENTREZGENE
  ENST00000409543.6 UniProtKB/Swiss-Prot
  ENST00000525201 ENTREZGENE
  ENST00000525201.5 UniProtKB/TrEMBL
  ENST00000525334.5 UniProtKB/TrEMBL
  ENST00000527644.2 UniProtKB/TrEMBL
  ENST00000530404.5 UniProtKB/TrEMBL
  ENST00000532375.5 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1450.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000214063 GTEx
HGNC ID HGNC:11859 ENTREZGENE
Human Proteome Map TSPAN4 Human Proteome Map
InterPro Tetraspanin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tetraspanin/Peripherin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tetraspanin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tetraspanin_EC2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:7106 UniProtKB/Swiss-Prot
NCBI Gene 7106 ENTREZGENE
OMIM 602644 OMIM
PANTHER PTHR19282 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TETRASPANIN-4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tetraspanin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA36560 PharmGKB
PIRSF Tetraspanin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS TMFOUR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  TM4_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48652 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8MVV6 ENTREZGENE, UniProtKB/TrEMBL
  B7WPM8 ENTREZGENE
  E9PMX4_HUMAN UniProtKB/TrEMBL
  E9PN41_HUMAN UniProtKB/TrEMBL
  E9PPX8_HUMAN UniProtKB/TrEMBL
  E9PSH3_HUMAN UniProtKB/TrEMBL
  J3KNL1_HUMAN UniProtKB/TrEMBL
  J3KQ42 ENTREZGENE, UniProtKB/TrEMBL
  O14817 ENTREZGENE
  Q6IAP6 ENTREZGENE
  TSN4_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B7WPM8 UniProtKB/TrEMBL
  Q6IAP6 UniProtKB/Swiss-Prot