Cep57 (centrosomal protein 57) - Rat Genome Database

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Gene: Cep57 (centrosomal protein 57) Rattus norvegicus
Analyze
Symbol: Cep57
Name: centrosomal protein 57
RGD ID: 1309884
Description: Predicted to enable fibroblast growth factor binding activity; microtubule binding activity; and protein homodimerization activity. Predicted to be involved in fibroblast growth factor receptor signaling pathway; protein homooligomerization; and spermatid development. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and microtubule cytoskeleton. Predicted to be active in centrosome. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome 2. Orthologous to human CEP57 (centrosomal protein 57); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3110002l15rik; centrosomal protein 57kDa; centrosomal protein of 57 kDa; LOC315423; RGD1309884; similar to translokin; translokin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8818,951,179 - 18,971,205 (-)NCBIGRCr8
mRatBN7.2810,669,588 - 10,689,257 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl810,669,590 - 10,689,249 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx814,656,395 - 14,676,043 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0812,954,121 - 12,973,769 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0810,930,498 - 10,950,158 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0812,335,430 - 12,355,425 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl812,335,432 - 12,355,091 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0812,285,706 - 12,305,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4810,608,688 - 10,627,914 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1810,608,258 - 10,628,586 (-)NCBI
Celera812,170,101 - 12,189,763 (-)NCBICelera
Cytogenetic Map8q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
hydrogen peroxide  (ISO)
lead(0)  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
mitomycin C  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenytoin  (EXP)
picoxystrobin  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centriolar satellite  (IEA,ISO)
centrosome  (IBA,IEA,ISO)
cytoplasm  (IEA,ISO)
cytosol  (IEA,ISO)
Golgi apparatus  (ISO)
microtubule  (IEA,ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10942595   PMID:12477932   PMID:12717444   PMID:12954732   PMID:14654843   PMID:18294141   PMID:21399614  


Genomics

Comparative Map Data
Cep57
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8818,951,179 - 18,971,205 (-)NCBIGRCr8
mRatBN7.2810,669,588 - 10,689,257 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl810,669,590 - 10,689,249 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx814,656,395 - 14,676,043 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0812,954,121 - 12,973,769 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0810,930,498 - 10,950,158 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0812,335,430 - 12,355,425 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl812,335,432 - 12,355,091 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0812,285,706 - 12,305,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4810,608,688 - 10,627,914 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1810,608,258 - 10,628,586 (-)NCBI
Celera812,170,101 - 12,189,763 (-)NCBICelera
Cytogenetic Map8q12NCBI
CEP57
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381195,790,498 - 95,832,693 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1195,789,965 - 95,832,693 (+)EnsemblGRCh38hg38GRCh38
GRCh371195,523,662 - 95,565,857 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361195,163,290 - 95,205,502 (+)NCBINCBI36Build 36hg18NCBI36
Celera1192,822,024 - 92,864,242 (+)NCBICelera
Cytogenetic Map11q21NCBI
HuRef1191,589,397 - 91,631,656 (+)NCBIHuRef
CHM1_11195,406,634 - 95,448,873 (+)NCBICHM1_1
T2T-CHM13v2.01195,797,891 - 95,840,118 (+)NCBIT2T-CHM13v2.0
Cep57
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39913,717,979 - 13,738,698 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl913,719,088 - 13,738,403 (-)EnsemblGRCm39 Ensembl
GRCm38913,807,783 - 13,827,407 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl913,807,792 - 13,827,107 (-)EnsemblGRCm38mm10GRCm38
MGSCv37913,612,232 - 13,631,537 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36913,558,192 - 13,577,449 (-)NCBIMGSCv36mm8
Celera911,086,224 - 11,105,529 (-)NCBICelera
Cytogenetic Map9A1NCBI
cM Map93.49NCBI
Cep57
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955412638,718 - 693,837 (+)NCBIChiLan1.0ChiLan1.0
CEP57
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2996,635,265 - 96,796,834 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11197,727,216 - 97,888,280 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01190,795,277 - 90,838,166 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11194,322,862 - 94,365,643 (+)NCBIpanpan1.1PanPan1.1panPan2
CEP57
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1215,314,290 - 5,360,474 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl215,314,449 - 5,361,154 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha215,306,946 - 5,372,017 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0215,470,572 - 5,535,631 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl215,489,231 - 5,535,379 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1215,265,268 - 5,330,343 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0215,326,888 - 5,391,987 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0215,374,577 - 5,439,676 (-)NCBIUU_Cfam_GSD_1.0
Cep57
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494780,630,996 - 80,670,623 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367001,875,795 - 1,915,003 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367001,874,509 - 1,914,688 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CEP57
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl927,812,917 - 27,859,568 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1927,812,944 - 27,858,293 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2931,728,611 - 31,738,258 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CEP57
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1187,046,915 - 87,088,999 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl187,046,639 - 87,093,786 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604338,725,753 - 38,769,778 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cep57
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473540,647,104 - 40,670,640 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cep57
47 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:87
Interacting mature miRNAs:105
Transcripts:ENSRNOT00000009318
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8124597739Rat
2317882Alcrsp24Alcohol response QTL 243.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)8125902202Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 29 36 20 19 20 1 1 74 33 41 11 1
Low 14 21 21 21 7 10 2 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000009318   ⟹   ENSRNOP00000009318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl810,669,590 - 10,689,249 (-)Ensembl
Rnor_6.0 Ensembl812,335,432 - 12,355,091 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104346   ⟹   ENSRNOP00000082973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl810,669,590 - 10,689,249 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111369   ⟹   ENSRNOP00000085671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl810,669,590 - 10,684,238 (-)Ensembl
RefSeq Acc Id: NM_001108124   ⟹   NP_001101594
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,183 - 18,970,844 (-)NCBI
mRatBN7.2810,669,588 - 10,689,249 (-)NCBI
Rnor_6.0812,335,430 - 12,355,091 (-)NCBI
Rnor_5.0812,285,706 - 12,305,716 (-)NCBI
RGSC_v3.4810,608,688 - 10,627,914 (-)RGD
Celera812,170,101 - 12,189,763 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242523   ⟹   XP_006242585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,970,617 (-)NCBI
mRatBN7.2810,669,593 - 10,688,863 (-)NCBI
Rnor_6.0812,335,430 - 12,354,881 (-)NCBI
Rnor_5.0812,285,706 - 12,305,716 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242524   ⟹   XP_006242586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,971,205 (-)NCBI
mRatBN7.2810,669,593 - 10,689,243 (-)NCBI
Rnor_6.0812,335,430 - 12,355,425 (-)NCBI
Rnor_5.0812,285,706 - 12,305,716 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039081340   ⟹   XP_038937268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,971,205 (-)NCBI
mRatBN7.2810,669,593 - 10,687,581 (-)NCBI
RefSeq Acc Id: XM_039081341   ⟹   XP_038937269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,963,030 (-)NCBI
mRatBN7.2810,669,588 - 10,681,451 (-)NCBI
RefSeq Acc Id: XM_039081342   ⟹   XP_038937270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,963,242 (-)NCBI
mRatBN7.2810,669,588 - 10,681,643 (-)NCBI
RefSeq Acc Id: XM_039081343   ⟹   XP_038937271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,963,024 (-)NCBI
mRatBN7.2810,669,588 - 10,681,449 (-)NCBI
RefSeq Acc Id: XM_039081348   ⟹   XP_038937276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,963,242 (-)NCBI
mRatBN7.2810,669,588 - 10,681,643 (-)NCBI
RefSeq Acc Id: XM_063265328   ⟹   XP_063121398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,970,337 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001101594   ⟸   NM_001108124
- UniProtKB: B4F7A7 (UniProtKB/Swiss-Prot),   A6JN77 (UniProtKB/TrEMBL),   A0A8I6A259 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242586   ⟸   XM_006242524
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A259 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242585   ⟸   XM_006242523
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A259 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000009318   ⟸   ENSRNOT00000009318
RefSeq Acc Id: XP_038937270   ⟸   XM_039081342
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038937276   ⟸   XM_039081348
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038937269   ⟸   XM_039081341
- Peptide Label: isoform X3
- UniProtKB: A6JN79 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937271   ⟸   XM_039081343
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038937268   ⟸   XM_039081340
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A259 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000085671   ⟸   ENSRNOT00000111369
RefSeq Acc Id: ENSRNOP00000082973   ⟸   ENSRNOT00000104346
RefSeq Acc Id: XP_063121398   ⟸   XM_063265328
- Peptide Label: isoform X1
Protein Domains
Cep57 centrosome localisation   Cep57 centrosome microtubule-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B4F7A7-F1-model_v2 AlphaFold B4F7A7 1-499 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695744
Promoter ID:EPDNEW_R6266
Type:initiation region
Name:Cep57_1
Description:centrosomal protein 57
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0812,355,123 - 12,355,183EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309884 AgrOrtholog
BioCyc Gene G2FUF-31706 BioCyc
Ensembl Genes ENSRNOG00000006792 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055007201 UniProtKB/Swiss-Prot
  ENSRNOG00060005720 UniProtKB/Swiss-Prot
  ENSRNOG00065011350 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009318 ENTREZGENE
  ENSRNOT00000009318.7 UniProtKB/Swiss-Prot
  ENSRNOT00000104346.1 UniProtKB/TrEMBL
  ENSRNOT00000111369.1 UniProtKB/TrEMBL
  ENSRNOT00055011956 UniProtKB/Swiss-Prot
  ENSRNOT00060009585 UniProtKB/Swiss-Prot
  ENSRNOT00065018463 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.58.90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7113445 IMAGE-MGC_LOAD
InterPro Cep57_CLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cep57_MT-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:315423 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94956 IMAGE-MGC_LOAD
NCBI Gene 315423 ENTREZGENE
PANTHER PTHR19336:SF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCHARACTERIZED DUF1167 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cep57_CLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cep57_MT_bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cep57 PhenoGen
RatGTEx ENSRNOG00000006792 RatGTEx
  ENSRNOG00055007201 RatGTEx
  ENSRNOG00060005720 RatGTEx
  ENSRNOG00065011350 RatGTEx
UniProt A0A8I6A259 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GA59_RAT UniProtKB/TrEMBL
  A6JN77 ENTREZGENE, UniProtKB/TrEMBL
  A6JN79 ENTREZGENE, UniProtKB/TrEMBL
  B4F7A7 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-04-27 Cep57  centrosomal protein 57  Cep57  centrosomal protein 57kDa  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-29 Cep57  centrosomal protein 57kDa  Cep57  centrosomal protein 57  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Cep57  centrosomal protein 57  RGD1309884  similar to translokin  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1309884  similar to translokin  RGD1309884_predicted  similar to translokin (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309884_predicted  similar to translokin (predicted)  LOC315423_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC315423_predicted  similar to translokin (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL