ADGRD1-AS1 (ADGRD1 antisense RNA 1) - Rat Genome Database

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Gene: ADGRD1-AS1 (ADGRD1 antisense RNA 1) Homo sapiens
Analyze
Symbol: ADGRD1-AS1
Name: ADGRD1 antisense RNA 1
RGD ID: 12799439
HGNC Page HGNC:53314
Description: INTERACTS WITH triclosan
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: LACAT8
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812130,990,626 - 130,993,976 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12130,990,138 - 130,993,976 (-)EnsemblGRCh38hg38GRCh38
GRCh3712131,475,171 - 131,478,521 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map12q24.33NCBI
CHM1_112131,296,017 - 131,299,369 (-)NCBICHM1_1
T2T-CHM13v2.012131,029,966 - 131,033,314 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
triclosan  (EXP)

References
Additional References at PubMed
PMID:16344560   PMID:25599403  


Genomics

Variants

.
Variants in ADGRD1-AS1
4 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12q24.23-24.33(chr12:118165459-133182322)x3 copy number gain See cases [RCV000050866] Chr12:118165459..133182322 [GRCh38]
Chr12:118603264..133758908 [GRCh37]
Chr12:117087647..132268981 [NCBI36]
Chr12:12q24.23-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123444758-133191400)x3 copy number gain See cases [RCV000051151] Chr12:123444758..133191400 [GRCh38]
Chr12:123929305..133767986 [GRCh37]
Chr12:122495258..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.23-24.33(chr12:119417382-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|See cases [RCV000053691] Chr12:119417382..133191400 [GRCh38]
Chr12:119855187..133767986 [GRCh37]
Chr12:118339570..132278059 [NCBI36]
Chr12:12q24.23-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123365769-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|See cases [RCV000053693] Chr12:123365769..133191400 [GRCh38]
Chr12:123850316..133767986 [GRCh37]
Chr12:122416269..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123509825-133191400)x3 copy number gain See cases [RCV000135535] Chr12:123509825..133191400 [GRCh38]
Chr12:123994372..133767986 [GRCh37]
Chr12:122560325..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:130965828-131650601)x3 copy number gain See cases [RCV000137029] Chr12:130965828..131650601 [GRCh38]
Chr12:131450373..132135146 [GRCh37]
Chr12:130016326..130701099 [NCBI36]
Chr12:12q24.33		 benign
GRCh38/hg38 12q24.31-24.33(chr12:120697672-133202490)x3 copy number gain See cases [RCV000137651] Chr12:120697672..133202490 [GRCh38]
Chr12:121135475..133779076 [GRCh37]
Chr12:119619858..132289149 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.21-24.33(chr12:114268403-133201316)x3 copy number gain See cases [RCV000143656] Chr12:114268403..133201316 [GRCh38]
Chr12:114706208..133777902 [GRCh37]
Chr12:113190591..132287975 [NCBI36]
Chr12:12q24.21-24.33		 pathogenic
GRCh38/hg38 12q24.21-24.33(chr12:115131583-133166920)x3 copy number gain See cases [RCV000053689] Chr12:115131583..133166920 [GRCh38]
Chr12:115569388..133743506 [GRCh37]
Chr12:114053771..132253579 [NCBI36]
Chr12:12q24.21-24.33		 pathogenic
GRCh38/hg38 12q24.32-24.33(chr12:126403612-133166920)x3 copy number gain See cases [RCV000053715] Chr12:126403612..133166920 [GRCh38]
Chr12:126888158..133743506 [GRCh37]
Chr12:125454111..132253579 [NCBI36]
Chr12:12q24.32-24.33		 pathogenic
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33		 pathogenic
NM_198827.5(ADGRD1):c.838A>G (p.Ile280Val) single nucleotide variant not specified [RCV004325065] Chr12:130992264 [GRCh38]
Chr12:131476809 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_198827.5(ADGRD1):c.938C>T (p.Ser313Leu) single nucleotide variant not specified [RCV004319290] Chr12:130992364 [GRCh38]
Chr12:131476909 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_198827.5(ADGRD1):c.838A>C (p.Ile280Leu) single nucleotide variant not specified [RCV004379363] Chr12:130992264 [GRCh38]
Chr12:131476809 [GRCh37]
Chr12:12q24.33		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:284
Count of miRNA genes:179
Interacting mature miRNAs:182
Transcripts:ENST00000536673, ENST00000542980
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 3 6 1 7 1 1 1 1 3 72
Low 67 35 314 11 89 12 224 43 181 7 420 737 1 40 188
Below cutoff 1606 1402 646 149 374 112 2263 1292 1112 50 486 618 43 864 1453 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000536673
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12130,990,161 - 130,993,967 (-)Ensembl
RefSeq Acc Id: ENST00000542980
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12130,990,138 - 130,993,976 (-)Ensembl
RefSeq Acc Id: NR_131950
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812130,990,626 - 130,993,976 (-)NCBI
CHM1_112131,296,017 - 131,299,369 (-)NCBI
T2T-CHM13v2.012131,029,966 - 131,033,314 (-)NCBI
Sequence:
RefSeq Acc Id: NR_131951
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812130,990,626 - 130,993,976 (-)NCBI
CHM1_112131,296,017 - 131,299,369 (-)NCBI
T2T-CHM13v2.012131,029,966 - 131,033,314 (-)NCBI
Sequence:
Promoters
RGD ID:15096679
Promoter ID:EPDNEWNC_H1521
Type:initiation region
Name:ADGRD1-AS1_1
Description:ADGRD1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:53314]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812130,993,983 - 130,994,043EPDNEWNC

Additional Information

Database Acc Id Source(s)
COSMIC ADGRD1-AS1 COSMIC
Ensembl Genes ENSG00000256151 Ensembl
GTEx ENSG00000256151 GTEx
HGNC ID HGNC:53314 ENTREZGENE
Human Proteome Map ADGRD1-AS1 Human Proteome Map
NCBI Gene ADGRD1-AS1 ENTREZGENE
RNAcentral URS00008E39B2 RNACentral
  URS00008E3A2B RNACentral