Znf398 (zinc finger protein 398) - Rat Genome Database

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Gene: Znf398 (zinc finger protein 398) Ictidomys tridecemlineatus
Analyze
Symbol: Znf398
Name: zinc finger protein 398
RGD ID: 12737317
Description: ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (inferred); regulation of DNA-templated transcription (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051187,614,198 - 7,652,074 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365275,253,276 - 5,285,224 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365275,253,329 - 5,286,055 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Znf398
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051187,614,198 - 7,652,074 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365275,253,276 - 5,285,224 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365275,253,329 - 5,286,055 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF398
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387149,126,408 - 149,183,042 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7149,126,416 - 149,183,042 (+)EnsemblGRCh38hg38GRCh38
GRCh377148,823,500 - 148,880,134 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367148,454,441 - 148,511,052 (+)NCBINCBI36Build 36hg18NCBI36
Build 347148,282,465 - 148,317,767NCBI
Celera7143,492,686 - 143,549,312 (+)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7142,900,949 - 142,957,456 (+)NCBIHuRef
CHM1_17148,831,593 - 148,888,532 (+)NCBICHM1_1
T2T-CHM13v2.07150,308,211 - 150,364,850 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27148,161,529 - 148,218,130 (+)NCBI
Zfp398
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39647,812,567 - 47,850,476 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl647,812,595 - 47,850,471 (+)EnsemblGRCm39 Ensembl
GRCm38647,835,633 - 47,873,542 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl647,835,661 - 47,873,537 (+)EnsemblGRCm38mm10GRCm38
MGSCv37647,785,660 - 47,818,256 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36647,765,281 - 47,797,843 (+)NCBIMGSCv36mm8
Celera648,372,166 - 48,397,762 (+)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map622.94NCBI
Zfp398
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8478,180,620 - 78,214,367 (+)NCBIGRCr8
mRatBN7.2476,849,672 - 76,881,075 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl476,849,681 - 76,876,243 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx482,061,986 - 82,088,379 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0477,836,324 - 77,862,717 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0476,277,788 - 76,304,182 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0477,519,018 - 77,546,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl477,519,028 - 77,545,589 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04142,188,819 - 142,215,380 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4475,975,752 - 76,002,315 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera471,798,375 - 71,824,733 (+)NCBICelera
Cytogenetic Map4q24NCBI
Znf398
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554914,424,599 - 4,452,516 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554914,424,602 - 4,451,026 (+)NCBIChiLan1.0ChiLan1.0
ZNF398
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26185,729,698 - 185,775,051 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1737,739,969 - 37,785,315 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07140,873,588 - 140,911,477 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17153,348,084 - 153,389,333 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7153,351,199 - 153,389,333 (+)Ensemblpanpan1.1panPan2
ZNF398
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11614,199,219 - 14,231,144 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1614,199,489 - 14,228,213 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1614,802,473 - 14,840,062 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01615,907,774 - 15,945,351 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1615,907,880 - 15,943,081 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11614,288,401 - 14,325,962 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01614,874,859 - 14,906,931 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,919,290 - 14,956,856 (+)NCBIUU_Cfam_GSD_1.0
LOC100522942
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9109,171,636 - 109,200,789 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19109,171,631 - 109,214,760 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29120,110,744 - 120,151,941 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF398
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121117,712,837 - 117,741,875 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21117,712,925 - 117,738,832 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607213,667,065 - 13,692,688 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf398
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248006,585,027 - 6,619,734 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248006,577,354 - 6,619,709 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000013383   ⟹   ENSSTOP00000011990
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365275,253,276 - 5,285,224 (+)Ensembl
RefSeq Acc Id: XM_021727247   ⟹   XP_021582922
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244051187,614,198 - 7,649,901 (-)NCBI
SpeTri2.0NW_0049365275,253,329 - 5,286,055 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040291296   ⟹   XP_040147230
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244051187,614,198 - 7,652,074 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021582922 (Get FASTA)   NCBI Sequence Viewer  
  XP_040147230 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000011990.3
GenBank Protein KAG3277267 (Get FASTA)   NCBI Sequence Viewer  
  KAG3277268 (Get FASTA)   NCBI Sequence Viewer  
  KAG3277269 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021582922   ⟸   XM_021727247
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040147230   ⟸   XM_040291296
- Peptide Label: isoform X1
- UniProtKB: I3MKW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000011990   ⟸   ENSSTOT00000013383
Protein Domains
C2H2-type   KRAB   KRAB-related


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013384 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013383.3 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box-rel UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene Znf398 ENTREZGENE
PANTHER KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 746-RELATED UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PROSITE KRAB UniProtKB/TrEMBL
  KRAB_RELATED UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt I3MKW5 ENTREZGENE, UniProtKB/TrEMBL