Mef2d (myocyte enhancer factor 2D) - Rat Genome Database

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Gene: Mef2d (myocyte enhancer factor 2D) Ictidomys tridecemlineatus
Analyze
Symbol: Mef2d
Name: myocyte enhancer factor 2D
RGD ID: 12735667
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN chondrocyte differentiation (ortholog); endochondral ossification (ortholog); osteoblast differentiation (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); intracellular membrane-bounded organelle (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: myocyte enhancer factor 2D, transcript variant X1; myocyte enhancer factor 2D, transcript variant X2; myocyte enhancer factor 2D, transcript variant X3; myocyte enhancer factor 2D, transcript variant X4; myocyte enhancer factor 2D, transcript variant X5; myocyte enhancer factor 2D, transcript variant X6; myocyte-specific enhancer factor 2D
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505826,629,915 - 26,652,822 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365805,660,016 - 5,675,166 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365805,660,306 - 5,685,333 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mef2d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505826,629,915 - 26,652,822 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365805,660,016 - 5,675,166 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365805,660,306 - 5,685,333 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEF2D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,463,727 - 156,500,775 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1156,463,727 - 156,500,779 (-)EnsemblGRCh38hg38GRCh38
GRCh371156,433,519 - 156,470,567 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,700,143 - 154,737,153 (-)NCBINCBI36Build 36hg18NCBI36
Build 341153,246,591 - 153,283,602NCBI
Celera1129,506,529 - 129,543,551 (-)NCBICelera
Cytogenetic Map1q22NCBI
HuRef1127,793,584 - 127,830,590 (-)NCBIHuRef
CHM1_11157,829,813 - 157,866,945 (-)NCBICHM1_1
T2T-CHM13v2.01155,602,298 - 155,639,356 (-)NCBIT2T-CHM13v2.0
Mef2d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39388,049,248 - 88,079,398 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl388,049,679 - 88,079,393 (+)EnsemblGRCm39 Ensembl
GRCm38388,141,941 - 88,172,091 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,142,372 - 88,172,086 (+)EnsemblGRCm38mm10GRCm38
MGSCv37387,946,317 - 87,973,089 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36388,228,354 - 88,254,650 (+)NCBIMGSCv36mm8
Celera388,181,996 - 88,208,762 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.78NCBI
Mef2d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82175,904,332 - 175,933,451 (+)NCBIGRCr8
mRatBN7.22173,606,054 - 173,635,620 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2173,606,490 - 173,634,457 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2180,751,841 - 180,777,592 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02178,774,196 - 178,799,948 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02173,373,781 - 173,399,532 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02187,511,775 - 187,541,285 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2187,512,164 - 187,538,026 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02206,915,181 - 206,944,302 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,221,078 - 180,246,917 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12180,171,183 - 180,197,019 (+)NCBI
Celera2167,553,069 - 167,578,692 (+)NCBICelera
Cytogenetic Map2q34NCBI
Mef2d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,569,399 - 2,602,579 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,569,399 - 2,602,580 (-)NCBIChiLan1.0ChiLan1.0
MEF2D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2193,343,978 - 93,381,688 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1193,075,869 - 93,113,583 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01131,806,705 - 131,844,420 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11135,637,823 - 135,664,623 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,637,801 - 135,653,866 (-)Ensemblpanpan1.1panPan2
MEF2D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,455,771 - 41,473,807 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,458,514 - 41,470,197 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha740,929,884 - 40,960,479 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0741,306,586 - 41,337,187 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl741,306,639 - 41,336,539 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1741,088,046 - 41,118,654 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0741,141,343 - 41,171,916 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0741,425,048 - 41,455,649 (+)NCBIUU_Cfam_GSD_1.0
MEF2D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,581,598 - 93,616,983 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1493,581,563 - 93,616,980 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24102,218,116 - 102,236,160 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MEF2D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1207,358,647 - 7,394,068 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl207,358,653 - 7,396,972 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660386,659,027 - 6,694,456 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mef2d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248851,687,572 - 1,714,238 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248851,685,423 - 1,714,462 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000019501   ⟹   ENSSTOP00000023159
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365805,660,302 - 5,675,164 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000034563   ⟹   ENSSTOP00000031109
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365805,660,016 - 5,675,164 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000034703   ⟹   ENSSTOP00000025346
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365805,660,302 - 5,675,166 (-)Ensembl
RefSeq Acc Id: XM_021730541   ⟹   XP_021586216
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505826,629,915 - 26,652,822 (-)NCBI
SpeTri2.0NW_0049365805,660,306 - 5,684,513 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021730542   ⟹   XP_021586217
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505826,629,915 - 26,644,756 (-)NCBI
SpeTri2.0NW_0049365805,660,306 - 5,685,333 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040287708   ⟹   XP_040143642
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505826,629,915 - 26,648,843 (-)NCBI
RefSeq Acc Id: XM_040287709   ⟹   XP_040143643
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505826,629,915 - 26,644,637 (-)NCBI
RefSeq Acc Id: XM_040287710   ⟹   XP_040143644
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505826,629,915 - 26,644,637 (-)NCBI
RefSeq Acc Id: XM_040287711   ⟹   XP_040143645
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505826,629,915 - 26,644,637 (-)NCBI
RefSeq Acc Id: XM_040287712   ⟹   XP_040143646
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505826,629,915 - 26,644,637 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021586217   ⟸   XM_021730542
- Peptide Label: isoform X1
- UniProtKB: A0A287DC54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021586216   ⟸   XM_021730541
- Peptide Label: isoform X1
- UniProtKB: A0A287DC54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040143642   ⟸   XM_040287708
- Peptide Label: isoform X1
- UniProtKB: A0A287DC54 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040143645   ⟸   XM_040287711
- Peptide Label: isoform X4
- UniProtKB: A0A287CVP5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040143643   ⟸   XM_040287709
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040143644   ⟸   XM_040287710
- Peptide Label: isoform X3
- UniProtKB: I3NFL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040143646   ⟸   XM_040287712
- Peptide Label: isoform X5
RefSeq Acc Id: ENSSTOP00000023159   ⟸   ENSSTOT00000019501
RefSeq Acc Id: ENSSTOP00000025346   ⟸   ENSSTOT00000034703
RefSeq Acc Id: ENSSTOP00000031109   ⟸   ENSSTOT00000034563
Protein Domains
MADS-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000025590 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000019501.2 UniProtKB/TrEMBL
  ENSSTOT00000034563.1 UniProtKB/TrEMBL
  ENSSTOT00000034703.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1810.10 UniProtKB/TrEMBL
InterPro HJURP_C UniProtKB/TrEMBL
  MADS_MEF2-like UniProtKB/TrEMBL
  TF_MADSbox UniProtKB/TrEMBL
  TF_MADSbox_sf UniProtKB/TrEMBL
NCBI Gene Mef2d ENTREZGENE
PANTHER MYOCYTE ENHANCER FACTOR 2D UniProtKB/TrEMBL
  MYOCYTE-SPECIFIC ENHANCER FACTOR 2A UniProtKB/TrEMBL
  SERUM RESPONSE FACTOR HOMOLOG UniProtKB/TrEMBL
Pfam HJURP_C UniProtKB/TrEMBL
  SRF-TF UniProtKB/TrEMBL
PRINTS MADSDOMAIN UniProtKB/TrEMBL
PROSITE MADS_BOX_1 UniProtKB/TrEMBL
  MADS_BOX_2 UniProtKB/TrEMBL
SMART MADS UniProtKB/TrEMBL
Superfamily-SCOP SSF55455 UniProtKB/TrEMBL
UniProt A0A287CVP5 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DC54 ENTREZGENE, UniProtKB/TrEMBL
  I3NFL2 ENTREZGENE, UniProtKB/TrEMBL