Thoc6 (THO complex subunit 6) - Rat Genome Database

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Gene: Thoc6 (THO complex subunit 6) Ictidomys tridecemlineatus
Analyze
Symbol: Thoc6
Name: THO complex subunit 6 (Ensembl:THO complex 6)
RGD ID: 12735650
Description: INVOLVED IN central nervous system development (inferred); mRNA export from nucleus (inferred); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED WITH Beaulieu-Boycott-Innes Syndrome (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN chromosome, telomeric region (inferred); nuclear body (inferred); nuclear speck (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: THO complex 6; THO complex 6 homolog; THO complex 6, transcript variant X1; THO complex 6, transcript variant X2; THO complex subunit 6 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,561,935 - 105,565,339 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,143,345 - 1,147,345 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,144,122 - 1,147,345 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Thoc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,561,935 - 105,565,339 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,143,345 - 1,147,345 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,144,122 - 1,147,345 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
THOC6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,024,035 - 3,027,750 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl163,024,027 - 3,027,755 (+)EnsemblGRCh38hg38GRCh38
GRCh37163,074,036 - 3,077,751 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,014,094 - 3,017,752 (+)NCBINCBI36Build 36hg18NCBI36
Celera163,279,588 - 3,283,311 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef163,045,606 - 3,049,329 (+)NCBIHuRef
CHM1_1163,073,906 - 3,077,630 (+)NCBICHM1_1
T2T-CHM13v2.0163,050,607 - 3,054,322 (+)NCBIT2T-CHM13v2.0
Thoc6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391723,887,592 - 23,892,891 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1723,887,588 - 23,892,856 (-)EnsemblGRCm39 Ensembl
GRCm381723,668,618 - 23,673,917 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,668,614 - 23,673,882 (-)EnsemblGRCm38mm10GRCm38
MGSCv371723,805,586 - 23,810,737 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,396,241 - 23,401,392 (-)NCBIMGSCv36mm8
Celera1724,174,757 - 24,179,976 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1711.97NCBI
Thoc6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,204,643 - 13,210,004 (-)NCBIGRCr8
mRatBN7.21012,700,051 - 12,705,411 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,700,051 - 12,706,925 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,443,443 - 17,448,809 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01016,932,232 - 16,937,602 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,432,693 - 12,438,058 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01012,989,135 - 12,994,495 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1012,989,135 - 12,994,495 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01012,812,180 - 12,817,540 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41012,933,304 - 12,938,664 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11012,933,477 - 12,934,565 (-)NCBI
Celera1012,395,353 - 12,400,712 (-)NCBICelera
Cytogenetic Map10q12NCBI
Thoc6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,314,100 - 14,317,724 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,314,100 - 14,317,726 (-)NCBIChiLan1.0ChiLan1.0
THOC6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2183,568,797 - 3,572,552 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1167,347,397 - 7,350,925 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,965,875 - 1,969,595 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,138,217 - 3,141,878 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,138,229 - 3,141,876 (+)Ensemblpanpan1.1panPan2
THOC6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,161,506 - 38,164,287 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,161,474 - 38,164,402 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,402,042 - 39,405,030 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0638,472,101 - 38,475,089 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,472,105 - 38,475,079 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,157,896 - 38,160,884 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,130,403 - 38,133,392 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,606,159 - 38,609,147 (-)NCBIUU_Cfam_GSD_1.0
THOC6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,161,434 - 39,164,707 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,161,442 - 39,164,631 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,535,339 - 40,538,529 (+)NCBISscrofa10.2Sscrofa10.2susScr3
THOC6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,767,338 - 2,771,040 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,767,634 - 2,771,812 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,061,270 - 28,065,055 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Thoc6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624824768,082 - 774,688 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla_female_1.0 EnsemblNW_004624824764,217 - 766,210 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624824764,185 - 772,426 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000010104   ⟹   ENSSTOP00000009064
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366941,144,222 - 1,146,741 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000031427   ⟹   ENSSTOP00000024148
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366941,143,345 - 1,147,345 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000042016   ⟹   ENSSTOP00000027692
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366941,144,222 - 1,147,302 (-)Ensembl
RefSeq Acc Id: XM_005337763   ⟹   XP_005337820
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344105,561,935 - 105,565,339 (+)NCBI
SpeTri2.0NW_0049366941,144,122 - 1,147,345 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021734895   ⟹   XP_021590570
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344105,562,252 - 105,565,339 (+)NCBI
SpeTri2.0NW_0049366941,144,122 - 1,147,218 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005337820 (Get FASTA)   NCBI Sequence Viewer  
  XP_021590570 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000009064.3
  ENSSTOP00000024148.1
  ENSSTOP00000027692.1
GenBank Protein KAG3259059 (Get FASTA)   NCBI Sequence Viewer  
  KAG3259060 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005337820   ⟸   XM_005337763
- Peptide Label: isoform X2
- UniProtKB: A0A287CS99 (UniProtKB/TrEMBL),   I3MEU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021590570   ⟸   XM_021734895
- Peptide Label: isoform X1
- UniProtKB: I3MEU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000009064   ⟸   ENSSTOT00000010104
RefSeq Acc Id: ENSSTOP00000024148   ⟸   ENSSTOT00000031427
RefSeq Acc Id: ENSSTOP00000027692   ⟸   ENSSTOT00000042016


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010100 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010104.3 UniProtKB/TrEMBL
  ENSSTOT00000031427.1 UniProtKB/TrEMBL
  ENSSTOT00000042016.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro THOC6 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Thoc6 ENTREZGENE
PANTHER PTHR44411 UniProtKB/TrEMBL
  THO COMPLEX SUBUNIT 6 HOMOLOG UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A287CS99 ENTREZGENE, UniProtKB/TrEMBL
  A0A287D2D9_ICTTR UniProtKB/TrEMBL
  I3MEU4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-30 Thoc6  THO complex subunit 6  Thoc6  THO complex 6  Symbol and/or name change 5135510 APPROVED