Orc2 (origin recognition complex subunit 2) - Rat Genome Database

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Gene: Orc2 (origin recognition complex subunit 2) Ictidomys tridecemlineatus
Analyze
Symbol: Orc2
Name: origin recognition complex subunit 2
RGD ID: 12733945
Description: ENCODES a protein that exhibits DNA replication origin binding (inferred); INVOLVED IN DNA replication (inferred); DNA replication initiation (inferred); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); Pulmonary Arterial Hypertension (ortholog); FOUND IN centrosome (ortholog); nuclear origin of replication recognition complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: origin recognition complex subunit 2, transcript variant X1; origin recognition complex subunit 2, transcript variant X2; origin recognition complex subunit 2, transcript variant X3; origin recognition complex subunit 2, transcript variant X4; origin recognition complex subunit 2, transcript variant X5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303158,244,624 - 158,288,326 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936726211,859 - 255,754 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936726215,483 - 259,867 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Orc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303158,244,624 - 158,288,326 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936726211,859 - 255,754 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936726215,483 - 259,867 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ORC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382200,908,977 - 200,963,660 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2200,908,977 - 200,963,680 (-)EnsemblGRCh38hg38GRCh38
GRCh372201,773,700 - 201,828,383 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362201,483,139 - 201,536,655 (-)NCBINCBI36Build 36hg18NCBI36
Build 342201,600,400 - 201,653,916NCBI
Celera2195,529,524 - 195,583,050 (-)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2193,626,266 - 193,679,712 (-)NCBIHuRef
CHM1_12201,780,893 - 201,834,423 (-)NCBICHM1_1
T2T-CHM13v2.02201,392,427 - 201,447,106 (-)NCBIT2T-CHM13v2.0
Orc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39158,501,933 - 58,544,114 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl158,501,930 - 58,544,268 (-)EnsemblGRCm39 Ensembl
GRCm38158,462,771 - 58,505,113 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl158,462,771 - 58,505,109 (-)EnsemblGRCm38mm10GRCm38
MGSCv37158,519,615 - 58,561,763 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36158,407,317 - 58,449,465 (-)NCBIMGSCv36mm8
Celera158,981,002 - 59,022,881 (-)NCBICelera
Cytogenetic Map1C1.3NCBI
cM Map129.1NCBI
Orc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8967,496,097 - 67,532,548 (-)NCBIGRCr8
mRatBN7.2960,001,631 - 60,038,301 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl960,001,910 - 60,038,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx968,497,057 - 68,526,891 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0973,612,987 - 73,642,822 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0971,931,062 - 71,960,894 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0965,350,630 - 65,387,293 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl965,350,627 - 65,387,169 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0965,157,924 - 65,194,576 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4957,125,684 - 57,155,508 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1957,272,665 - 57,302,490 (-)NCBI
Celera957,445,799 - 57,475,616 (-)NCBICelera
Cytogenetic Map9q31NCBI
Orc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955403577,955 - 628,068 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955403576,268 - 628,068 (+)NCBIChiLan1.0ChiLan1.0
ORC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213103,536,891 - 103,599,237 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B103,550,709 - 103,615,470 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B88,166,351 - 88,221,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B206,325,661 - 206,380,874 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B206,325,661 - 206,380,647 (-)Ensemblpanpan1.1panPan2
ORC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13710,109,825 - 10,155,588 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3710,111,496 - 10,151,876 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3710,995,051 - 11,040,792 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03710,015,322 - 10,061,228 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3710,015,322 - 10,061,310 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1379,996,794 - 10,042,534 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0379,974,603 - 10,020,315 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0379,968,534 - 10,014,278 (-)NCBIUU_Cfam_GSD_1.0
ORC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15104,613,610 - 104,656,492 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115104,612,727 - 104,656,558 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215115,941,048 - 115,954,008 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ORC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11086,567,350 - 86,629,693 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1086,564,332 - 86,629,855 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040112,790,444 - 112,851,284 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Orc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624889227,510 - 268,784 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624889224,658 - 269,815 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000022579   ⟹   ENSSTOP00000016021
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936726211,859 - 255,754 (-)Ensembl
RefSeq Acc Id: XM_005338896   ⟹   XP_005338953
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303158,244,624 - 158,288,326 (-)NCBI
SpeTri2.0NW_004936726215,483 - 259,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735642   ⟹   XP_021591317
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303158,244,624 - 158,288,326 (-)NCBI
SpeTri2.0NW_004936726215,483 - 259,867 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040294683   ⟹   XP_040150617
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303158,244,624 - 158,288,326 (-)NCBI
RefSeq Acc Id: XM_040294684   ⟹   XP_040150618
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303158,244,624 - 158,288,325 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005338953   ⟸   XM_005338896
- Peptide Label: isoform X1
- UniProtKB: I3MV76 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021591317   ⟸   XM_021735642
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_040150617   ⟸   XM_040294683
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040150618   ⟸   XM_040294684
- Peptide Label: isoform X4
RefSeq Acc Id: ENSSTOP00000016021   ⟸   ENSSTOT00000022579


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000019442 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000022579.2 UniProtKB/TrEMBL
InterPro ORC2 UniProtKB/TrEMBL
NCBI Gene Orc2 ENTREZGENE
PANTHER ORIGIN RECOGNITION COMPLEX SUBUNIT 2 UniProtKB/TrEMBL
  PTHR14052 UniProtKB/TrEMBL
Pfam ORC2 UniProtKB/TrEMBL
UniProt I3MV76 ENTREZGENE, UniProtKB/TrEMBL