Adgrb3 (adhesion G protein-coupled receptor B3) - Rat Genome Database

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Gene: Adgrb3 (adhesion G protein-coupled receptor B3) Ictidomys tridecemlineatus
Analyze
Symbol: Adgrb3
Name: adhesion G protein-coupled receptor B3
RGD ID: 12731483
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); GTPase activator activity (inferred); INVOLVED IN maintenance of synapse structure (ortholog); motor learning (ortholog); neuron remodeling (ortholog); ASSOCIATED WITH Dwarfism (ortholog); FOUND IN cerebellar climbing fiber to Purkinje cell synapse (ortholog); postsynaptic density membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Bai3; brain-specific angiogenesis inhibitor 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494666,625,989 - 67,296,544 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936618786,816 - 1,455,747 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936618783,363 - 1,453,620 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Dwarfism  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Adgrb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494666,625,989 - 67,296,544 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936618786,816 - 1,455,747 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936618783,363 - 1,453,620 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38668,635,282 - 69,389,506 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl668,635,282 - 69,390,571 (+)EnsemblGRCh38hg38GRCh38
GRCh37669,345,174 - 70,099,398 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36669,402,353 - 70,156,124 (+)NCBINCBI36Build 36hg18NCBI36
Build 34669,404,157 - 70,156,120NCBI
Celera669,732,521 - 70,486,170 (+)NCBICelera
Cytogenetic Map6q12-q13NCBI
HuRef666,533,139 - 67,288,476 (+)NCBIHuRef
CHM1_1669,511,896 - 70,265,714 (+)NCBICHM1_1
T2T-CHM13v2.0669,812,849 - 70,568,164 (+)NCBIT2T-CHM13v2.0
Adgrb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39125,106,557 - 25,869,338 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl125,106,557 - 25,868,788 (-)EnsemblGRCm39 Ensembl
GRCm38125,067,476 - 25,834,772 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl125,067,476 - 25,829,707 (-)EnsemblGRCm38mm10GRCm38
MGSCv37125,124,321 - 25,886,552 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36125,012,096 - 25,774,253 (-)NCBIMGSCv36mm8
Celera124,897,174 - 25,644,393 (-)NCBICelera
Cytogenetic Map1A5NCBI
cM Map110.39NCBI
Adgrb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8934,917,474 - 35,645,350 (-)NCBIGRCr8
mRatBN7.2927,421,168 - 28,148,979 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl927,421,168 - 28,148,855 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx935,938,752 - 36,662,915 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0941,052,747 - 41,779,167 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0939,366,779 - 40,090,913 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0931,280,623 - 32,022,535 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl931,281,316 - 32,019,205 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0930,095,583 - 30,833,059 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4923,759,340 - 24,495,409 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1923,760,837 - 24,496,680 (-)NCBI
Celera924,954,095 - 25,681,415 (-)NCBICelera
Cytogenetic Map9q21NCBI
Adgrb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554883,806,695 - 4,508,421 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554883,803,859 - 4,509,043 (+)NCBIChiLan1.0ChiLan1.0
ADGRB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2588,640,831 - 89,391,317 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1686,576,148 - 87,326,609 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0666,484,739 - 67,238,607 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1669,785,260 - 70,537,440 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl669,788,604 - 70,536,820 (+)Ensemblpanpan1.1panPan2
ADGRB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11231,336,791 - 32,056,238 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1231,340,176 - 32,054,228 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1231,196,863 - 31,913,751 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01231,888,025 - 32,595,925 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1231,888,029 - 32,595,922 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11231,395,758 - 32,103,918 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01231,449,609 - 32,156,711 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01231,564,774 - 32,276,003 (+)NCBIUU_Cfam_GSD_1.0
ADGRB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl148,886,491 - 49,619,769 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1148,885,885 - 49,619,783 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2155,579,281 - 55,774,193 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1175,543,587 - 6,287,255 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl175,543,556 - 6,000,742 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605811,579,590 - 12,426,876 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adgrb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475326,287,621 - 26,980,325 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475326,284,931 - 26,980,937 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000005485   ⟹   ENSSTOP00000004907
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936618787,437 - 1,452,999 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000034104   ⟹   ENSSTOP00000025722
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366181,310,084 - 1,455,747 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000039011   ⟹   ENSSTOP00000030586
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936618786,816 - 1,452,999 (+)Ensembl
RefSeq Acc Id: XM_021732558   ⟹   XP_021588233
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494666,625,989 - 67,296,544 (+)NCBI
SpeTri2.0NW_004936618783,363 - 1,453,617 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040282896   ⟹   XP_040138830
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494666,625,990 - 67,296,544 (+)NCBI
RefSeq Acc Id: XM_040282897   ⟹   XP_040138831
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494666,625,990 - 67,296,544 (+)NCBI
RefSeq Acc Id: XM_040282898   ⟹   XP_040138832
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494666,625,990 - 67,296,544 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021588233 (Get FASTA)   NCBI Sequence Viewer  
  XP_040138830 (Get FASTA)   NCBI Sequence Viewer  
  XP_040138831 (Get FASTA)   NCBI Sequence Viewer  
  XP_040138832 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004907.3
  ENSSTOP00000025722.1
  ENSSTOP00000030586.1
Reference Protein Sequences
RefSeq Acc Id: XP_021588233   ⟸   XM_021732558
- Peptide Label: isoform X2
- UniProtKB: I3M658 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040138832   ⟸   XM_040282898
- Peptide Label: isoform X3
- UniProtKB: I3M658 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040138831   ⟸   XM_040282897
- Peptide Label: isoform X1
- UniProtKB: A0A287DAQ6 (UniProtKB/TrEMBL),   I3M658 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040138830   ⟸   XM_040282896
- Peptide Label: isoform X1
- UniProtKB: A0A287DAQ6 (UniProtKB/TrEMBL),   I3M658 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000030586   ⟸   ENSSTOT00000039011
RefSeq Acc Id: ENSSTOP00000025722   ⟸   ENSSTOT00000034104
RefSeq Acc Id: ENSSTOP00000004907   ⟸   ENSSTOT00000005485
Protein Domains
CUB   G-protein coupled receptors family 2 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000005432 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000005485.3 UniProtKB/TrEMBL
  ENSSTOT00000034104.1 UniProtKB/TrEMBL
  ENSSTOT00000039011.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.610 UniProtKB/TrEMBL
  2.20.100.10 UniProtKB/TrEMBL
  2.60.220.50 UniProtKB/TrEMBL
  4.10.1240.10 UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro AGRB_N UniProtKB/TrEMBL
  CUB_dom UniProtKB/TrEMBL
  GAIN_dom_N UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_brain_angio_inhib UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
NCBI Gene Adgrb3 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR B3 UniProtKB/TrEMBL
  ADHESION G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  AGRB_N UniProtKB/TrEMBL
  GAIN UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  HRM UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PRINTS BAIPRECURSOR UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/TrEMBL
PROSITE CUB UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
SMART GPS UniProtKB/TrEMBL
  HormR UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP SSF82895 UniProtKB/TrEMBL
UniProt A0A287CWP2_ICTTR UniProtKB/TrEMBL
  A0A287DAQ6 ENTREZGENE, UniProtKB/TrEMBL
  I3M658 ENTREZGENE, UniProtKB/TrEMBL