Ptpn20 (protein tyrosine phosphatase non-receptor type 20) - Rat Genome Database

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Gene: Ptpn20 (protein tyrosine phosphatase non-receptor type 20) Ictidomys tridecemlineatus
Analyze
Symbol: Ptpn20
Name: protein tyrosine phosphatase non-receptor type 20
RGD ID: 12729325
Description: ENCODES a protein that exhibits protein tyrosine phosphatase activity (inferred); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN centriolar satellite (inferred); cytoplasm (inferred); cytoplasmic side of plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tyrosine-protein phosphatase non-receptor type 20
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721380,899,848 - 80,974,947 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367282,116,780 - 2,176,317 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367282,102,676 - 2,176,882 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ptpn20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721380,899,848 - 80,974,947 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367282,116,780 - 2,176,317 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367282,102,676 - 2,176,882 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPN20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381046,911,428 - 47,003,653 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1046,911,396 - 47,002,488 (+)EnsemblGRCh38hg38GRCh38
GRCh371048,737,040 - 48,827,934 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361048,357,048 - 48,447,930 (-)NCBINCBI36Build 36hg18NCBI36
Celera1045,164,481 - 45,182,568 (-)NCBICelera
Cytogenetic Map10q11.22NCBI
HuRef1043,492,180 - 43,529,513 (-)NCBIHuRef
CHM1_11048,901,986 - 48,992,848 (-)NCBICHM1_1
T2T-CHM13v2.01047,800,189 - 47,916,646 (+)NCBIT2T-CHM13v2.0
Ptpn20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391433,311,150 - 33,362,711 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1433,311,164 - 33,362,711 (+)EnsemblGRCm39 Ensembl
GRCm381433,589,193 - 33,640,754 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1433,589,207 - 33,640,754 (+)EnsemblGRCm38mm10GRCm38
MGSCv371434,402,456 - 34,453,940 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361432,418,362 - 32,469,846 (+)NCBIMGSCv36mm8
Celera1429,843,947 - 29,895,427 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.51NCBI
Ptpn20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8168,891,828 - 8,956,037 (+)NCBIGRCr8
mRatBN7.2168,885,585 - 8,949,805 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,893,324 - 8,949,783 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx168,912,901 - 8,969,351 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01610,057,607 - 10,114,055 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0168,907,992 - 8,964,448 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0169,907,584 - 9,973,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl169,907,598 - 9,973,516 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01611,858,454 - 11,922,332 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4169,200,233 - 9,256,753 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1169,192,522 - 9,243,208 (+)NCBI
Celera166,258,200 - 6,314,563 (-)NCBICelera
Cytogenetic Map16p16NCBI
Ptpn20
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555561,867,005 - 1,944,933 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555561,850,933 - 1,943,318 (+)NCBIChiLan1.0ChiLan1.0
PTPN20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2860,317,411 - 60,408,226 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11060,321,406 - 60,413,468 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01046,102,341 - 46,194,493 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PTPN20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12864,398 - 181,398 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2867,065 - 216,086 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha28291,083 - 405,913 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.028235,752 - 350,683 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl28235,772 - 350,780 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12842,965 - 157,761 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02884,168 - 198,993 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.028170,137 - 285,052 (-)NCBIUU_Cfam_GSD_1.0
PTPN20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1488,766,361 - 88,838,470 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11488,763,753 - 88,838,962 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21496,372,516 - 96,465,352 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPN20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1943,663,542 - 43,766,810 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl943,694,321 - 43,764,229 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660483,472,093 - 3,535,863 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000035583   ⟹   ENSSTOP00000027113
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367282,116,780 - 2,176,317 (+)Ensembl
RefSeq Acc Id: XM_040273308   ⟹   XP_040129242
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721380,899,848 - 80,974,947 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040129242 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000027113.1
GenBank Protein KAG3264993 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040129242   ⟸   XM_040273308
RefSeq Acc Id: ENSSTOP00000027113   ⟸   ENSSTOT00000035583
Protein Domains
Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000034893 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000035583.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/TrEMBL
InterPro Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTPase_domain UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
NCBI Gene Ptpn20 ENTREZGENE
PANTHER TYROSINE-PROTEIN PHOSPHATASE UniProtKB/TrEMBL
  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 20 UniProtKB/TrEMBL
Pfam Y_phosphatase UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
UniProt A0A287D0L5_ICTTR UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 Ptpn20  protein tyrosine phosphatase non-receptor type 20    protein tyrosine phosphatase, non-receptor type 20  Symbol and/or name change 5135510 APPROVED