Cntrob (centrobin, centriole duplication and spindle assembly protein) - Rat Genome Database

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Gene: Cntrob (centrobin, centriole duplication and spindle assembly protein) Ictidomys tridecemlineatus
Analyze
Symbol: Cntrob
Name: centrobin, centriole duplication and spindle assembly protein
RGD ID: 12704006
Description: ENCODES a protein that exhibits protein domain specific binding (inferred); INVOLVED IN centriole replication (inferred); centrosome separation (inferred); mitotic cytokinetic process (inferred); ASSOCIATED WITH common variable immunodeficiency (ortholog); cone-rod dystrophy 6 (ortholog); Diamond-Blackfan anemia (ortholog); FOUND IN centrosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: centrobin; centrobin, centriole duplication and spindle assembly protein, transcript variant X1; centrobin, centriole duplication and spindle assembly protein, transcript variant X2; centrobin, centriole duplication and spindle assembly protein, transcript variant X3; centrobin, centriole duplication and spindle assembly protein, transcript variant X4; centrobin, centriole duplication and spindle assembly protein, transcript variant X5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,700,460 - 47,716,775 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,175,562 - 1,191,222 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,174,559 - 1,191,171 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centriole  (IEA)
centrosome  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Cntrob
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,700,460 - 47,716,775 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,175,562 - 1,191,222 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,174,559 - 1,191,171 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNTROB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,932,081 - 7,949,920 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,932,101 - 7,949,920 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,835,399 - 7,853,238 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,776,198 - 7,793,621 (+)NCBINCBI36Build 36hg18NCBI36
Celera177,863,187 - 7,880,713 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,730,040 - 7,747,892 (+)NCBIHuRef
CHM1_1177,844,229 - 7,862,013 (+)NCBICHM1_1
T2T-CHM13v2.0177,837,509 - 7,855,338 (+)NCBIT2T-CHM13v2.0
Cntrob
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,188,735 - 69,214,720 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,190,313 - 69,214,601 (-)EnsemblGRCm39 Ensembl
GRCm381169,297,909 - 69,323,898 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,299,487 - 69,323,775 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,112,998 - 69,137,375 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,115,691 - 69,139,970 (-)NCBIMGSCv36mm8
Celera1176,253,419 - 76,277,856 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.51NCBI
Cntrob
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,521,338 - 54,546,569 (-)NCBIGRCr8
mRatBN7.21054,022,523 - 54,047,793 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,022,852 - 54,044,849 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,684,543 - 58,706,468 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,173,159 - 58,195,082 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,681,256 - 53,703,227 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,901,929 - 55,927,121 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,901,901 - 55,924,158 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,644,004 - 55,666,957 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,094,489 - 56,116,421 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,108,146 - 56,129,842 (-)NCBI
Celera1053,179,449 - 53,201,359 (-)NCBICelera
Cytogenetic Map10q24NCBI
Cntrob
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,993,952 - 9,009,928 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,993,528 - 9,010,829 (-)NCBIChiLan1.0ChiLan1.0
CNTROB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21915,530,146 - 15,546,805 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11717,496,297 - 17,512,824 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,967,297 - 7,983,743 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,953,617 - 7,970,148 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,953,660 - 7,970,148 (+)Ensemblpanpan1.1panPan2
CNTROB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,777,242 - 32,811,747 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,777,341 - 32,811,518 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,908,508 - 32,948,110 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,874,335 - 32,914,229 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,889,100 - 32,914,223 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,842,045 - 32,881,648 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,798,079 - 32,837,667 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,977,207 - 33,017,099 (+)NCBIUU_Cfam_GSD_1.0
CNTROB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,181,642 - 53,201,667 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,181,096 - 53,201,670 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,532,441 - 55,602,642 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNTROB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,320,557 - 7,337,746 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,320,586 - 7,338,369 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,070,347 - 14,087,586 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cntrob
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,514,609 - 10,532,563 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,514,593 - 10,532,661 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000000146   ⟹   ENSSTOP00000000129
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365951,175,562 - 1,191,222 (+)Ensembl
RefSeq Acc Id: XM_005332831   ⟹   XP_005332888
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,700,461 - 47,716,775 (+)NCBI
SpeTri2.0NW_0049365951,174,559 - 1,190,885 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021731377   ⟹   XP_021587052
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,700,460 - 47,716,775 (+)NCBI
SpeTri2.0NW_0049365951,174,559 - 1,190,775 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021731378   ⟹   XP_021587053
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,700,460 - 47,716,775 (+)NCBI
SpeTri2.0NW_0049365951,174,559 - 1,190,775 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021731379   ⟹   XP_021587054
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,700,460 - 47,716,775 (+)NCBI
SpeTri2.0NW_0049365951,174,559 - 1,191,171 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021731380   ⟹   XP_021587055
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,700,461 - 47,716,775 (+)NCBI
SpeTri2.0NW_0049365951,174,559 - 1,190,831 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040269398   ⟹   XP_040125332
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,700,461 - 47,716,775 (+)NCBI
RefSeq Acc Id: XM_040269399   ⟹   XP_040125333
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,700,462 - 47,716,775 (+)NCBI
RefSeq Acc Id: XM_040269400   ⟹   XP_040125334
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,700,460 - 47,716,775 (+)NCBI
RefSeq Acc Id: XM_040269401   ⟹   XP_040125335
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,702,864 - 47,716,775 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005332888   ⟸   XM_005332831
- Peptide Label: isoform X3
- UniProtKB: I3LW21 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021587054   ⟸   XM_021731379
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021587055   ⟸   XM_021731380
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_021587052   ⟸   XM_021731377
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021587053   ⟸   XM_021731378
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040125334   ⟸   XM_040269400
- Peptide Label: isoform X8
RefSeq Acc Id: XP_040125332   ⟸   XM_040269398
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040125333   ⟸   XM_040269399
- Peptide Label: isoform X7
RefSeq Acc Id: XP_040125335   ⟸   XM_040269401
- Peptide Label: isoform X9
RefSeq Acc Id: ENSSTOP00000000129   ⟸   ENSSTOT00000000146


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000145 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000146.3 UniProtKB/TrEMBL
InterPro Centrobin UniProtKB/TrEMBL
NCBI Gene Cntrob ENTREZGENE
PANTHER CENTROBIN UniProtKB/TrEMBL
  PTHR34439 UniProtKB/TrEMBL
UniProt I3LW21 ENTREZGENE, UniProtKB/TrEMBL