Tcea2 (transcription elongation factor A2)

Gene: Tcea2 (transcription elongation factor A2) Ictidomys tridecemlineatus

Analyze

Symbol:

Tcea2

Name:

transcription elongation factor A2

RGD ID:

12679656

Description:

ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); nucleic acid binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); FOUND IN centrosome (inferred); nucleoplasm (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

transcription elongation factor A protein 2; transcription elongation factor A2, transcript variant X1; transcription elongation factor A2, transcript variant X2; transcription elongation factor A2, transcript variant X3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	195,789,352 - 195,796,792 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	11,242,739 - 11,250,260 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	11,243,021 - 11,251,216 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

positive regulation of transcription by RNA polymerase II (ISO)

transcription elongation by RNA polymerase II (IEA)

Cellular Component

centrosome (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

DNA binding (IEA)

metal ion binding (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase II transcription elongation pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tcea2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	195,789,352 - 195,796,792 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	11,242,739 - 11,250,260 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	11,243,021 - 11,251,216 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TCEA2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	64,055,596 - 64,072,347 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	64,049,836 - 64,072,347 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	62,688,325 - 62,703,700 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	62,158,883 - 62,174,143 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	62,158,882 - 62,174,144	NCBI
Celera	20	59,374,545 - 59,389,785 (+)	NCBI		Celera
Cytogenetic Map	20	q13.33	NCBI
HuRef	20	59,422,225 - 59,437,466 (+)	NCBI		HuRef
CHM1_1	20	62,589,462 - 62,604,716 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	65,875,622 - 65,892,426 (+)	NCBI		T2T-CHM13v2.0

Tcea2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	181,322,090 - 181,329,860 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	181,322,103 - 181,329,864 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	181,680,297 - 181,688,067 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	181,680,310 - 181,688,071 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	181,415,015 - 181,422,756 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	181,609,716 - 181,617,457 (+)	NCBI		MGSCv36	mm8
Celera	2	185,762,702 - 185,770,433 (+)	NCBI		Celera
Cytogenetic Map	2	H4	NCBI
cM Map	2	103.72	NCBI

Tcea2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	189,173,756 - 189,181,633 (+)	NCBI		GRCr8
mRatBN7.2	3	168,796,244 - 168,804,125 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	168,796,331 - 168,804,116 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	173,175,741 - 173,183,550 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	182,134,832 - 182,142,641 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	178,797,259 - 178,805,065 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	177,187,686 - 177,195,898 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	177,188,044 - 177,195,894 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	180,896,548 - 180,904,402 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	170,831,286 - 170,839,091 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	170,737,321 - 170,745,127 (+)	NCBI
Celera	3	163,783,634 - 163,791,446 (-)	NCBI		Celera
Cytogenetic Map	3	q43	NCBI

Tcea2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955528	186,642 - 194,058 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955528	186,642 - 194,058 (-)	NCBI	ChiLan1.0	ChiLan1.0

TCEA2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	69,880,980 - 69,890,213 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	69,873,001 - 69,882,229 (+)	NCBI		NHGRI_mPanPan1
PanPan1.1	20	61,977,338 - 61,986,592 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	61,976,869 - 61,986,592 (+)	Ensembl	panpan1.1		panPan2

TCEA2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	47,508,161 - 47,512,399 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	47,508,136 - 47,537,250 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	46,639,396 - 46,646,271 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	48,644,476 - 48,651,329 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	24	47,489,097 - 47,495,956 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	47,613,543 - 47,620,400 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	48,352,514 - 48,359,386 (+)	NCBI		UU_Cfam_GSD_1.0

TCEA2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	62,866,377 - 62,888,787 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	62,866,594 - 62,888,790 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TCEA2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	174,158 - 184,237 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	174,134 - 182,943 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	47,607,379 - 47,629,161 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tcea2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	29,692,006 - 29,699,383 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	29,691,983 - 29,699,383 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013358621	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021726438	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021726439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040273940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040273943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000000045 ⟹ ENSSTOP00000000039

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936514	11,244,143 - 11,250,260 (+)	Ensembl

RefSeq Acc Id:

ENSSTOT00000037586 ⟹ ENSSTOP00000029799

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936514	11,242,739 - 11,250,260 (+)	Ensembl

RefSeq Acc Id:

XM_013358621 ⟹ XP_013214075

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	195,789,352 - 195,796,792 (+)	NCBI
SpeTri2.0	NW_004936514	11,243,024 - 11,250,433 (+)	NCBI

Sequence:

show sequence

GGGGCGGGGACTCCGCGTCCCATCATGCAGTGCGCAGCCGGCGATCGGGGGGGTTTGGGCCGAG
GGTCGCTGCGGCTGCGGCCCTGGTCCGGCCGGGCTGGGTTGCTGAGCTGAGCAGGGTGCTGGCC
CCAAGGCGATGATGGGCAAGGAGGAGGAAATTGCGCGGATCGCCCGGAGGTTGGACAAGATGGT
GACCAGAAAGAGCGCGGAGGGAGCCATGGACCTGCTGCGGGAGCTGAAGGCCATGCCTATCACT
CTACACCTGCTCCAGTCCACCCGTGTTGGGATGTCTGTCAACGCCCTGCGGAAACAGAGCTCGG
ACGAGGAGGTCATTGCGCTGGCCAAGTCCCTCATCAAGTCCTGGAAGAAGCTCCTGGGTGTGGA
TGCTTCTGATGCCAAAACCAGGAACCGGGGAAAGGGCACACCTCTGCCCACATCATCCTCAAAG
GATGGCTCAGAGGCCATGGATCCCAGCCGCAAGAGGCCGGAGCTGCCCAGGATGCTGTCCACCC
CAAGGATTACCACGTTTCCCCCAGTGCCTGTTACCTGTGATGCTGTGCGCAACAAGTGCCGGGA
GATGCTCACCACTGCCCTGCAAACAGACCATGACCATGCGGCTGTTGGTGCAGACTGTGAGCGA
CTGTCGGCCCAGATTGAGGAATGCATCTTCCGGGATGTGGGAAACACAGACATGAAGTACAAGA
ACCGTGTGCGCAGTCGCATTGCCAACCTGAAGGATGCCAAGAACCCTGACCTCCGGCGGAATGT
GCTGTGTGGTGCCATAACCCCCCAGCAGATTGCGGTGATGACATCAGAGGAGATGGCCAGTGAC
GAGCTGAAGGAGATCCGCAAGGCCATGACCAAGGAGGCCATCCGTGAGCACCAGATGGCACGCA
CAGGTGGCACTCAGACAGACCTGTTCACCTGTGGCAAGTGCAGGAAGAAGAACTGTACCTACAC
GCAGGTACAGACCCGCAGCTCTGATGAGCCCATGACCACCTTTGTTGTTTGCAATGAATGTGGA
AACCGCTGGAAGTTCTGCTGAGCACTTGTGCAGTTGCGCTATAGCCCCAGGTCCTGGCCAATGC
TGCCCCTCCTGCATTCTTGGTGGACACAGCTTCTCTGGAGACCCCCAGTAGGCGGCATGCCCTG
CCCCAGCTGCCTGGTGTGCACCTTTCTGCCCTTTGCCCTGTTATTAAATGTTTTGTTTGCCATC
TT

hide sequence

RefSeq Acc Id:

XM_040273940 ⟹ XP_040129874

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	195,789,356 - 195,796,792 (+)	NCBI

RefSeq Acc Id:

XM_040273943 ⟹ XP_040129877

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	195,789,614 - 195,796,792 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_013214075	(Get FASTA)	NCBI Sequence Viewer
	XP_040129874	(Get FASTA)	NCBI Sequence Viewer
	XP_040129877	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000000039.3
	ENSSTOP00000029799.1
GenBank Protein	KAG3263743	(Get FASTA)	NCBI Sequence Viewer
	KAG3263744	(Get FASTA)	NCBI Sequence Viewer
	KAG3263745	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_013214075 ⟸ XM_013358621
- Peptide Label:	isoform X1
- UniProtKB:	I3LVW1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MMGKEEEIARIARRLDKMVTRKSAEGAMDLLRELKAMPITLHLLQSTRVGMSVNALRKQSSDEE VIALAKSLIKSWKKLLGVDASDAKTRNRGKGTPLPTSSSKDGSEAMDPSRKRPELPRMLSTPRI TTFPPVPVTCDAVRNKCREMLTTALQTDHDHAAVGADCERLSAQIEECIFRDVGNTDMKYKNRV RSRIANLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGG TQTDLFTCGKCRKKNCTYTQVQTRSSDEPMTTFVVCNECGNRWKFC hide sequence

RefSeq Acc Id:	XP_040129874 ⟸ XM_040273940
- Peptide Label:	isoform X2
- UniProtKB:	A0A287D8E3 (UniProtKB/TrEMBL), I3LVW1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040129877 ⟸ XM_040273943
- Peptide Label:	isoform X3
- UniProtKB:	I3LVW1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000029799 ⟸ ENSSTOT00000037586

RefSeq Acc Id:

ENSSTOP00000000039 ⟸ ENSSTOT00000000045

Protein Domains

TFIIS central TFIIS N-terminal TFIIS-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000000044	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000000045.3	UniProtKB/TrEMBL
	ENSSTOT00000037586.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.472.30	UniProtKB/TrEMBL
	1.20.930.10	UniProtKB/TrEMBL
	2.20.25.10	UniProtKB/TrEMBL
InterPro	TF_IIS-typ	UniProtKB/TrEMBL
	TFIIS/CRSP70_N_sub	UniProtKB/TrEMBL
	TFIIS/LEDGF_dom_sf	UniProtKB/TrEMBL
	TFIIS_cen_dom	UniProtKB/TrEMBL
	TFIIS_cen_dom_sf	UniProtKB/TrEMBL
	TFIIS_N	UniProtKB/TrEMBL
	TFSII	UniProtKB/TrEMBL
	Znf_TFIIS	UniProtKB/TrEMBL
NCBI Gene	Tcea2	ENTREZGENE
PANTHER	TRANSCRIPTION ELONGATION FACTOR A PROTEIN 2	UniProtKB/TrEMBL
	TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	Med26	UniProtKB/TrEMBL
	TFIIS_C	UniProtKB/TrEMBL
	TFIIS_M	UniProtKB/TrEMBL
PIRSF	TF_IIS	UniProtKB/TrEMBL
PROSITE	TFIIS_CENTRAL	UniProtKB/TrEMBL
	TFIIS_N	UniProtKB/TrEMBL
	ZF_TFIIS_1	UniProtKB/TrEMBL
	ZF_TFIIS_2	UniProtKB/TrEMBL
SMART	TFS2M	UniProtKB/TrEMBL
	TFS2N	UniProtKB/TrEMBL
	ZnF_C2C2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46942	UniProtKB/TrEMBL
	SSF47676	UniProtKB/TrEMBL
	Zinc beta-ribbon	UniProtKB/TrEMBL
UniProt	A0A287D8E3	ENTREZGENE, UniProtKB/TrEMBL
	I3LVW1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - CTD

RGD Manual Annotations