Barhl1 (BarH like homeobox 1) - Rat Genome Database

Name: Barhl1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Barhl1 (BarH like homeobox 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Barhl1

Name:

BarH like homeobox 1

RGD ID:

12661392

Description:

ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN midbrain development (ortholog); negative regulation of neuron apoptotic process (ortholog); negative regulation of outer hair cell apoptotic process (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); developmental and epileptic encephalopathy 14 (ortholog); Ehlers-Danlos syndrome classic type 1 (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BARHL1 (BarH like homeobox 1)	NCBI	Ortholog
Mus musculus (house mouse):	Barhl1 (BarH like homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Barhl1 (BarH-like homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Barhl1 (BarH like homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BARHL1 (BarH like homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BARHL1 (BarH like homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BARHL1 (BarH like homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BARHL1 (BarH like homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Barhl1 (BarH like homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	199,343,376 - 199,351,136 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	19,111,726 - 19,119,677 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	19,112,479 - 19,119,677 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

developmental and epileptic encephalopathy 14 (ISO)

Ehlers-Danlos syndrome classic type 1 (ISO)

genetic disease (ISO)

Hearing Loss (ISO)

high grade glioma (ISO)

Leigh disease (ISO)

primary coenzyme Q10 deficiency 7 (ISO)

Rafiq syndrome (ISO)

triple-receptor negative breast cancer (ISO)

tuberous sclerosis 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

midbrain development (IEA,ISO)

negative regulation of neuron apoptotic process (IEA,ISO)

negative regulation of outer hair cell apoptotic process (IEA,ISO)

neuron apoptotic process (IEA,ISO)

neuron migration (IEA,ISO)

outer hair cell apoptotic process (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of DNA-templated transcription (IEA)

sensory perception of sound (IEA,ISO)

Cellular Component

nucleus (IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

sequence-specific double-stranded DNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Barhl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	199,343,376 - 199,351,136 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	19,111,726 - 19,119,677 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	19,112,479 - 19,119,677 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BARHL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	132,582,606 - 132,590,252 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	132,582,606 - 132,590,252 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	135,457,993 - 135,465,639 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	134,447,814 - 134,455,461 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	132,487,546 - 132,495,194	NCBI
Celera	9	105,999,743 - 106,007,390 (+)	NCBI		Celera
Cytogenetic Map	9	q34.13	NCBI
HuRef	9	104,951,812 - 104,959,454 (+)	NCBI		HuRef
CHM1_1	9	135,608,371 - 135,616,013 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	144,793,810 - 144,801,451 (+)	NCBI		T2T-CHM13v2.0

Barhl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	28,797,692 - 28,807,996 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	28,797,691 - 28,806,680 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	28,907,680 - 28,917,984 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	28,907,679 - 28,916,668 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	28,763,200 - 28,771,960 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	28,729,682 - 28,738,430 (-)	NCBI		MGSCv36	mm8
Celera	2	28,613,544 - 28,622,304 (-)	NCBI		Celera
Cytogenetic Map	2	A3	NCBI
cM Map	2	19.38	NCBI

Barhl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	32,639,283 - 32,646,605 (-)	NCBI		GRCr8
mRatBN7.2	3	12,241,327 - 12,248,649 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	12,241,327 - 12,248,649 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	15,314,424 - 15,321,756 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	23,899,395 - 23,906,727 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	22,153,843 - 22,161,175 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	7,491,234 - 7,498,555 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	7,491,234 - 7,498,555 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	12,841,460 - 12,848,781 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	7,917,842 - 7,925,164 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	7,918,141 - 7,925,464 (-)	NCBI
Celera	3	7,020,613 - 7,027,935 (-)	NCBI		Celera
Cytogenetic Map	3	p12	NCBI

Barhl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	1,959,634 - 1,966,247 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	1,955,906 - 1,970,110 (+)	NCBI	ChiLan1.0	ChiLan1.0

BARHL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	6,768,517 - 6,778,456 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	6,770,853 - 6,780,706 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	103,698,024 - 103,709,834 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	132,331,662 - 132,343,116 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	132,331,770 - 132,338,661 (+)	Ensembl	panpan1.1		panPan2

BARHL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	51,704,590 - 51,711,726 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	51,703,936 - 51,712,093 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	50,968,439 - 50,976,455 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	52,596,767 - 52,604,794 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	52,597,590 - 52,604,205 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	51,376,679 - 51,384,690 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	51,701,143 - 51,709,148 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	51,780,866 - 51,788,879 (-)	NCBI		UU_Cfam_GSD_1.0

BARHL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	272,373,402 - 272,381,224 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	272,373,125 - 272,380,223 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	306,405,596 - 306,412,475 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BARHL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	5,549,484 - 5,557,348 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	5,549,234 - 5,556,945 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666079	10,081,270 - 10,089,322 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Barhl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	3,765,714 - 3,772,315 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	3,765,938 - 3,772,347 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021723439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000023736 ⟹ ENSSTOP00000021864

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936487	19,111,726 - 19,119,677 (+)	Ensembl

RefSeq Acc Id:

XM_021723439 ⟹ XP_021579114

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	199,343,376 - 199,351,136 (+)	NCBI
SpeTri2.0	NW_004936487	19,112,479 - 19,119,677 (+)	NCBI

Sequence:

show sequence

CTTTTGGATCTAATGCGCACAGGAGGTTGGCCCCAAGCTCCAGCGCTCCCCCAAGGCTGAACTC
TGTCCAAGGTGCCCGCAGGCTCCCTGCCCGCCTTCCCCATGCCAGCCCGCAGCTAGGGGCAGGG
GCAGCGGCGGCTGGGGTTGGGGGTGGGTGGGGAGCTTTGGGGGAGGACAGGTCGCAGCTTGGCT
ATGGAAGGCTCCAATGGCTTTGGGATCGACTCCATTCTCTCCCACCGTGCGGGCAGCCCCGCCC
TTCCCAAGGGGGACCCCTTGCTCGGGGACTGCCGCTCACCCTTGGAGCTGAGTCCACGCTCGGA
GAGCAGCAGCGATTGCTCTTCACCAGCCTCGCCAGGAAGGGACTGTCTGGAGACGGGCACCCCG
CGGCCTGGCGGGGCATCGGGCCCAGGTTTGGACTCCCACCTGCAGCCGGGGCAGCTCTCAGCCC
CAGCCCAGTCGCGCACCGTCACCTCCTCCTTTCTGATCAGGGACATCCTTGCCGACTGCAAACC
ACTCGCGGCCTGTGCACCCTACTCTAGCAGCGGGCAGCCAGCAGCCCCTGAGCCTGGGGGCCGC
CTTGTGGCCAAGGCCGGGGAGGACTTTAGAGACAAGCTGGACAAAAGTGGCAGCAACGCCTCAT
CAGACTCTGAGTATAAAGTGAAGGAGGAGGGAGACCGCGAGATCTCCAGCTCTCGGGACAGTCC
CCCAGTGCGCCTGAAAAAGCCACGCAAGGCGCGCACCGCCTTCACCGACCATCAGCTGGCGCAG
CTGGAGCGCAGCTTCGAGCGGCAGAAGTACCTGAGCGTGCAGGACCGCATGGAGCTGGCCGCCT
CGCTCAACCTCACCGACACGCAGGTCAAGACCTGGTACCAGAACCGCAGGACTAAATGGAAGCG
ACAGACCGCCGTCGGGCTGGAGCTGCTGGCAGAGGCGGGCAATTACTCAGCGCTCCAGCGGATG
TTCCCGTCGCCTTATTTCTACCCGCAGAGTCTGGTTTCCAACCTGGACCCTGGTGCCGCGCTCT
ACCTGTACCGCGGCCCCAGCGCGCCGCCTCCGGCCCTCCAGAGACCTCTGGTGCCCCGCATCCT
CATCCACGGACTCCAGGGCGCCAGCGAGCCACCCCCGCCGCTGCCCCCGCTGGCCGGCGTCCTC
CCGCGCGCCGCGCAGCCTCGGTGAGGCGCCCGCCCGCCCCCCGGCCGCGCTCCATGGCCTCGGG
CCACGCTCGGCGTCCGTCACTTTCGCCCGCCTCATCGGGCGCTCGCTCCGCGACCCCCCGGGGC
GGGGGCTGCCTGGCTCTCCGCGGCGCCCCACCCAGTGTCCCCGAAGGGTCAAATGCCAAGTCCA
CTGAGGCCCGGACCCAACTGCGGCTCCCTAGCCCCTCGGCGTCCTCTCTCCGGCCGCCCCACTT
CTGCGCCACCGCCCGCCTCCAGCCCTCCCGCTCTGCCCGCTCCTCCAGGCGCCCCGTTCCCGCC
CCCAGGAGCGGGCGGGGGTGACCCCCTGCCTCGCCCCCTCCCTCTGCCCTTCCCTGCTCGCCGG
GGACCCTCTCCCCGCGCCCCTGCGGGCTCGGCGGGGCAGCGGCGCGCGGAGCTCCACCCGCTCA
GGCTGCGGCGCCCAGGCCGCGGCTGCGCTGTACATACCGTGTGCAAAGTGTATATGAAGTTATT
TATTCGTGACCCATGAGCCCGTGACCGTGTCCGTGAATCAGTGAGTCTGTGGCCTGTGCCCTCC
CCTCTGGGTGGGGCAGGGAGGCCGAGGGCTCGCCCGCCGCCCCGGCCCCGCCTCCACCTCCAGC
CCGGTCCCCGGGTCAGCCAGGCCTCGTGGGTTCTCTTTTTTAAATGTCGAAATAAACTTCTTAC
AAACGACCTGGCGCCTGTCC

hide sequence

Protein Sequences


Protein RefSeqs	XP_021579114	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000021864.1
GenBank Protein	KAG3288238	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021579114 ⟸ XM_021723439

- UniProtKB:

I3NBW7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETGTP
RPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGR
LVAKAGEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQ
LERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRM
FPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLAGVL
PRAAQPR

hide sequence

RefSeq Acc Id:

ENSSTOP00000021864 ⟸ ENSSTOT00000023736

Protein Domains

Homeobox

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000024230	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000023736.2	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox-like_sf	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_dom	UniProtKB/TrEMBL
	Homeobox_metazoa	UniProtKB/TrEMBL
NCBI Gene	Barhl1	ENTREZGENE
PANTHER	HOMEO BOX HB9 LIKE A-RELATED	UniProtKB/TrEMBL
	HOMEOBOX DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	Homeodomain	UniProtKB/TrEMBL
PRINTS	HOMEOBOX	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46689	UniProtKB/TrEMBL
UniProt	I3NBW7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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