Hagh (hydroxyacylglutathione hydrolase)

Gene: Hagh (hydroxyacylglutathione hydrolase) Ictidomys tridecemlineatus

Analyze

Symbol:

Hagh

Name:

hydroxyacylglutathione hydrolase

RGD ID:

12646239

Description:

ENCODES a protein that exhibits hydroxyacylglutathione hydrolase activity (ortholog); INVOLVED IN glutathione metabolic process (ortholog); PARTICIPATES IN glyoxalase metabolic pathway; Leigh disease pathway; primary hyperoxaluria type 2 pathway; ASSOCIATED WITH epilepsy (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); mitochondrial matrix (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

hydroxyacylglutathione hydrolase, mitochondrial; hydroxyacylglutathione hydrolase, transcript variant X1; hydroxyacylglutathione hydrolase, transcript variant X2; hydroxyacylglutathione hydrolase, transcript variant X3; hydroxyacylglutathione hydrolase, transcript variant X4; hydroxyacylglutathione hydrolase, transcript variant X5; hydroxyacylglutathione hydrolase, transcript variant X6; hydroxyacylglutathione hydrolase, transcript variant X7

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	104,510,713 - 104,528,007 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936694	2,181,501 - 2,194,007 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936694	2,181,475 - 2,200,469 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

epilepsy (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

Glyoxalase II Deficiency (ISO)

idiopathic generalized epilepsy (ISO)

short-rib thoracic dysplasia 9 with or without polydactyly (ISO)

tuberous sclerosis 2 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glutathione biosynthetic process (IEA)

glutathione metabolic process (IEA,ISO)

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione (IEA)

Cellular Component

cytoplasm (IEA)

mitochondrial matrix (IEA)

mitochondrion (IEA)

Molecular Function

hydrolase activity (IEA)

hydroxyacylglutathione hydrolase activity (IEA,ISO)

metal ion binding (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

glyoxalase metabolic pathway (ISO)

Leigh disease pathway (ISO)

primary hyperoxaluria type 2 pathway (ISO)

pyruvate decarboxylase deficiency pathway (ISO)

pyruvate dehydrogenase E1 deficiency pathway (ISO)

pyruvate kinase deficiency of red cells pathway (ISO)

pyruvate metabolic pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Hagh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	104,510,713 - 104,528,007 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936694	2,181,501 - 2,194,007 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936694	2,181,475 - 2,200,469 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HAGH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	1,807,629 - 1,827,194 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	1,795,620 - 1,827,157 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	1,857,630 - 1,877,195 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	1,799,105 - 1,817,196 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	1,799,105 - 1,817,163	NCBI
Celera	16	2,071,349 - 2,089,441 (-)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	1,781,967 - 1,800,219 (-)	NCBI		HuRef
CHM1_1	16	1,859,060 - 1,877,163 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	1,823,468 - 1,843,048 (-)	NCBI		T2T-CHM13v2.0

Hagh
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	25,056,863 - 25,083,424 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	25,059,117 - 25,083,424 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	24,839,781 - 24,864,450 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	24,840,143 - 24,864,450 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	24,987,435 - 25,001,395 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	24,578,147 - 24,592,050 (+)	NCBI		MGSCv36	mm8
Celera	17	25,377,454 - 25,391,223 (+)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	12.53	NCBI

Hagh
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	14,379,400 - 14,394,046 (+)	NCBI		GRCr8
mRatBN7.2	10	13,874,883 - 13,889,527 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	13,875,241 - 13,889,504 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	18,622,292 - 18,636,594 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	18,111,152 - 18,125,454 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	13,610,369 - 13,624,671 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	14,215,913 - 14,230,506 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	14,216,155 - 14,230,515 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	14,032,006 - 14,046,521 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	14,106,047 - 14,117,459 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	14,106,046 - 14,117,459 (+)	NCBI
Celera	10	13,554,443 - 13,568,735 (+)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

Hagh
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	15,451,910 - 15,465,211 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	15,451,910 - 15,465,211 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC100992459
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	2,075,668 - 2,122,827 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	5,857,103 - 5,880,906 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	431,417 - 455,211 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	1,864,372 - 1,865,276 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

HAGH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	39,076,364 - 39,105,646 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	39,084,513 - 39,105,592 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	40,323,559 - 40,344,553 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	39,400,917 - 39,422,090 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	39,375,311 - 39,422,080 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	39,077,630 - 39,098,788 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	39,050,207 - 39,071,366 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	39,528,902 - 39,549,839 (+)	NCBI		UU_Cfam_GSD_1.0

HAGH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	3	40,139,099 - 40,162,921 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

HAGH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	1,705,436 - 1,730,896 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	1,713,542 - 1,730,797 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	29,352,945 - 29,370,176 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hagh
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624913	434,537 - 446,061 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624913	426,554 - 446,061 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005337819	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005337820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013364075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013364076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040276868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000009110 ⟹ ENSSTOP00000008167

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936694	2,181,501 - 2,194,007 (+)	Ensembl

RefSeq Acc Id:

ENSSTOT00000031316 ⟹ ENSSTOP00000026847

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936694	2,181,531 - 2,193,948 (+)	Ensembl

RefSeq Acc Id:

ENSSTOT00000039131 ⟹ ENSSTOP00000027580

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936694	2,181,681 - 2,194,007 (+)	Ensembl

RefSeq Acc Id:

XM_005337819 ⟹ XP_005337876

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	104,510,713 - 104,527,999 (-)	NCBI
SpeTri2.0	NW_004936694	2,181,486 - 2,194,307 (+)	NCBI

Sequence:

show sequence

CGCCGGCGTTGCGGTCCCGTGCGGGGCAGTGCAGCCCTGCAGGTCATGGTGCTCGGCCGCAGGC
TGTTCGGCTGCCGGAGCCTCGCCGCGCTGGGAGTCGCCTGCGCGCGCCGCGGCCTTGGCCCAGC
CCTGCTGGGAACCCTCCTGTATTACACAGATTTAAGGAAGAGTTTGACTGTGGAACAGAGCGCC
ATGAAGGTTGAGCTACTGCCTGCCCTGACCGACAACTACATGTACCTGATCATTGACAAGGACA
CCAGGGAGGCTGCCATTGTGGACCCTGTGCAGCCCCAGAAGGTTGTAGAAACCGTGAGAAAGTA
TGGTGTGAAGCTGACCACGGTGCTCACCACACACCACCACTGGGACCACGCTGGCGGGAACGAG
AAGCTGGTCAAGCTGCAGCCAGGGCTGAAGGTGTATGGGGGTGACGACCGTATCGGGGCCCTGA
CTCACAAAGTCACGCACCTGTTCACTCTGCAGGTGGGGAGTCTCCATGTTAAATGCTTATCAAC
CCCCTGCCACACCTCAGGACACATCTGTTACTTGGTGAGCAAGCCTGGTGGTCCAGATCCCCCT
GCTGTGTTCACAGGTGACACCCTGTTTGTGGCCGGCTGTGGGAAGTTCTATGAAGGGACTGCAG
AAGAGATGTATAGAGCACTGCTGGAGGTCCTGGGCCGGCTCCCTCCAGACACAAAAGTCTACTG
TGGCCATGAGTACACCATCAGCAACCTCAAGTTCGCACGCCACGTGGAGCCCAGCAACACTGCT
GTTCTGGAGAAGCTGGCCTGGGCCAAGGAGAAATATGCCACTGGGGAGCCCACGGTGCCATCCA
CCATCGCTGAGGAGTTCACCTACAACCCCTTCATGAGAGTGAGGGAGAAGACGGTGCAGCAGCA
TGCCGGCCAGACTGACCCCGTGGCCACCATGCGCTACATCCGCAGGGAGAAGGACCAGTTCAAG
GTGCCGCCAGACTGAAGCACAGCACCAGCACGCGGGAGAGGAGGGTGGGCGACCCTGGGATTGC
ACTGCGGGGGGGGGGGGGACATTGGTTCTAGGTCAACTCCAGAGCCCTTAGATGGAGTTACAAA
TGTTCTAATGCATATTTATAAGAGAAAAAGTTTTAAAGTATTTATTCCCACACCCTCTGCTGGC
AGACTTTGCATTTTCTCTGGCCTTCACCTGTGGCTGTCTCCAGCCAGAGCCAGGCCCCGCCCTG
TCCTCCTGACTCTGCAGGGAGAGTGGAGGTGGCTGGCTTGCCCACAGGCCCTTCCTTCCAGCTC
CTGGCCTCCCGATCTGTCTGCCCACAGCAATGAAAGCCCACCTTCACCTGG

hide sequence

RefSeq Acc Id:

XM_005337820 ⟹ XP_005337877

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	104,515,477 - 104,528,007 (-)	NCBI
SpeTri2.0	NW_004936694	2,181,482 - 2,198,541 (+)	NCBI

Sequence:

show sequence

CCGACGCCGGCGTTGCGGTCCCGTGCGGGGCAGTGCAGCCCTGCAGGTCATGGTGCTCGGCCGC
AGGCTGTTCGGCTGCCGGAGCCTCGCCGCGCTGGGAGTCGCCTGCGCGCGCCGCGGCCTTGATT
TAAGGAAGAGTTTGACTGTGGAACAGAGCGCCATGAAGGTTGAGCTACTGCCTGCCCTGACCGA
CAACTACATGTACCTGATCATTGACAAGGACACCAGGGAGGCTGCCATTGTGGACCCTGTGCAG
CCCCAGAAGGTTGTAGAAACCGTGAGAAAGTATGGTGTGAAGCTGACCACGGTGCTCACCACAC
ACCACCACTGGGACCACGCTGGCGGGAACGAGAAGCTGGTCAAGCTGCAGCCAGGGCTGAAGGT
GTATGGGGGTGACGACCGTATCGGGGCCCTGACTCACAAAGTCACGCACCTGTTCACTCTGCAG
GTGGGGAGTCTCCATGTTAAATGCTTATCAACCCCCTGCCACACCTCAGGACACATCTGTTACT
TGGTGAGCAAGCCTGGTGGTCCAGATCCCCCTGCTGTGTTCACAGGTGACACCCTGTTTGTGGC
CGGCTGTGGGAAGTTCTATGAAGGGACTGCAGAAGAGATGTATAGAGCACTGCTGGAGGTCCTG
GGCCGGCTCCCTCCAGACACAAAAGTCTACTGTGGCCATGAGTACACCATCAGCAACCTCAAGT
TCGCACGCCACGTGGAGCCCAGCAACACTGCTGTTCTGGAGAAGCTGGCCTGGGCCAAGGAGAA
ATATGCCACTGGGGAGCCCACGGTGCCATCCACCATCGCTGAGGAGTTCACCTACAACCCCTTC
ATGAGAGTGAGGGAGAAGACGGTGCAGCAGCATGCCGGCCAGACTGACCCCGTGGCCACCATGC
GCTACATCCGCAGGGAGAAGGACCAGTTCAAGTTGGAAGCTGTCATTCATCAGTCTGCCAAACC
ATGCCAAGTGGGGATTCTGGGAAGAAGGCTTCCCCCAAGGTCGGGCAGGAGTCAGAACCTGGAG
GATCCAGCAGAGCCTGGCCTGGGACTGGTGACAGCAAGAGGTTGGCCCTGCCTCCACACTCCCT
CCCCAGTGCTGTTCCCTCTGATCCAGTGATCCATCCCTCAGCAGTCACCTCTGCTCAGAAGAAG
GGTCACTCTGCTCAGACCCACACATGCCTGGGAGTCCACTGACAGCAGAGGCAGGACACGAGAT
CCCTTCTCTGCCTCCTCGCCACCTCGGGGTCAGAGTTCATTTGCAGCCGGGTATGGTGGTGTGC
ACCTGCAATCCCCGTGACTTGGGGGGCTGAGGCGGGAGG

hide sequence

RefSeq Acc Id:

XM_013364075 ⟹ XP_013219529

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	104,515,477 - 104,527,784 (-)	NCBI
SpeTri2.0	NW_004936694	2,181,673 - 2,198,539 (+)	NCBI

Sequence:

show sequence

GGAGCCGAGACTGCTGGTCCGGCAAGGAGCGGACGCGGCCACCAGGCCTCGGCGGGGCCGGGCG
TGGTGAGGGTGTGGGCACAACCGTTCCTGCCTGCCGCCTCGGCCTACAGATCTTCCCCTCTCGG
CGTCTGGCGACCGCGGGCCGCCGCGCCGTGGCCAACAGCCTGCCAGCCGAGTCCCAGTCCCGCG
GCAGCCGCCCAGGTTCACAGTGCGTGACACACCCTTGCTAAGGAAGGAGCCTGCCCATTGAGGT
TCTCAGGACGCAGTCTCTCCCTCGGGGACGCGGTGTCCCCGGAGCGCTGCATCGGAGCCCCTAA
CCCATGCGCTGGGGCGGCAGGCCCAGCCCTGCTGGGAACCCTCCTGTATTACACAGATTTAAGG
AAGAGTTTGACTGTGGAACAGAGCGCCATGAAGGTTGAGCTACTGCCTGCCCTGACCGACAACT
ACATGTACCTGATCATTGACAAGGACACCAGGGAGGCTGCCATTGTGGACCCTGTGCAGCCCCA
GAAGGTTGTAGAAACCGTGAGAAAGTATGGTGTGAAGCTGACCACGGTGCTCACCACACACCAC
CACTGGGACCACGCTGGCGGGAACGAGAAGCTGGTCAAGCTGCAGCCAGGGCTGAAGGTGTATG
GGGGTGACGACCGTATCGGGGCCCTGACTCACAAAGTCACGCACCTGTTCACTCTGCAGGTGGG
GAGTCTCCATGTTAAATGCTTATCAACCCCCTGCCACACCTCAGGACACATCTGTTACTTGGTG
AGCAAGCCTGGTGGTCCAGATCCCCCTGCTGTGTTCACAGGTGACACCCTGTTTGTGGCCGGCT
GTGGGAAGTTCTATGAAGGGACTGCAGAAGAGATGTATAGAGCACTGCTGGAGGTCCTGGGCCG
GCTCCCTCCAGACACAAAAGTCTACTGTGGCCATGAGTACACCATCAGCAACCTCAAGTTCGCA
CGCCACGTGGAGCCCAGCAACACTGCTGTTCTGGAGAAGCTGGCCTGGGCCAAGGAGAAATATG
CCACTGGGGAGCCCACGGTGCCATCCACCATCGCTGAGGAGTTCACCTACAACCCCTTCATGAG
AGTGAGGGAGAAGACGGTGCAGCAGCATGCCGGCCAGACTGACCCCGTGGCCACCATGCGCTAC
ATCCGCAGGGAGAAGGACCAGTTCAAGTTGGAAGCTGTCATTCATCAGTCTGCCAAACCATGCC
AAGTGGGGATTCTGGGAAGAAGGCTTCCCCCAAGGTCGGGCAGGAGTCAGAACCTGGAGGATCC
AGCAGAGCCTGGCCTGGGACTGGTGACAGCAAGAGGTTGGCCCTGCCTCCACACTCCCTCCCCA
GTGCTGTTCCCTCTGATCCAGTGATCCATCCCTCAGCAGTCACCTCTGCTCAGAAGAAGGGTCA
CTCTGCTCAGACCCACACATGCCTGGGAGTCCACTGACAGCAGAGGCAGGACACGAGATCCCTT
CTCTGCCTCCTCGCCACCTCGGGGTCAGAGTTCATTTGCAGCCGGGTATGGTGGTGTGCACCTG
CAATCCCCGTGACTTGGGGGGCTGAGGCGGGA

hide sequence

RefSeq Acc Id:

XM_013364076 ⟹ XP_013219530

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	104,516,026 - 104,528,000 (-)	NCBI
SpeTri2.0	NW_004936694	2,181,475 - 2,193,437 (+)	NCBI

Sequence:

show sequence

GCAATTGCCGACGCCGGCGTTGCGGTCCCGTGCGGGGCAGTGCAGCCCTGCAGGTCATGGTGCT
CGGCCGCAGGCTGTTCGGCTGCCGGAGCCTCGCCGCGCTGGGAGTCGCCTGCGCGCGCCGCGGC
CTTGGCCCAGCCCTGCTGGGAACCCTCCTGTATTACACAGATTTAAGGAAGAGTTTGACTGTGG
AACAGAGCGCCATGAAGGTTGAGCTACTGCCTGCCCTGACCGACAACTACATGTACCTGATCAT
TGACAAGGACACCAGGGAGGCTGCCATTGTGGACCCTGTGCAGCCCCAGAAGGTTGTAGAAACC
GTGAGAAAGTATGGTGTGAAGCTGACCACGGTGCTCACCACACACCACCACTGGGACCACGCTG
GCGGGAACGAGAAGCTGGTCAAGCTGCAGCCAGGGCTGAAGGTGTATGGGGGTGACGACCGTAT
CGGGGCCCTGACTCACAAAGTCACGCACCTGTTCACTCTGCAGGTGACACCCTGTTTGTGGCCG
GCTGTGGGAAGTTCTATGAAGGGACTGCAGAAGAGATGTATAGAGCACTGCTGGAGGTCCTGGG
CCGGCTCCCTCCAGACACAAAAGTCTACTGTGGCCATGAGTACACCATCAGCAACCTCAAGTTC
GCACGCCACGTGGAGCCCAGCAACACTGCTGTTCTGGAGAAGCTGGCCTGGGCCAAGGAGAAAT
ATGCCACTGGGGAGCCCACGGTGCCATCCACCATCGCTGAGGAGTTCACCTACAACCCCTTCAT
GA

hide sequence

RefSeq Acc Id:

XM_021734960 ⟹ XP_021590635

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	104,515,477 - 104,527,951 (-)	NCBI
SpeTri2.0	NW_004936694	2,181,530 - 2,198,539 (+)	NCBI

Sequence:

show sequence

CATGGTGCTCGGCCGCAGGCTGTTCGGCTGCCGGAGCCTCGCCGCGCTGGGAGTCGCCTGCGCG
CGCCGCGGCCTTGGCTGAGGACCTGAGGCTGCATCCTGTGTCTCCAGGCCCAGCCCTGCTGGGA
ACCCTCCTGTATTACACAGATTTAAGGAAGAGTTTGACTGTGGAACAGAGCGCCATGAAGGTTG
AGCTACTGCCTGCCCTGACCGACAACTACATGTACCTGATCATTGACAAGGACACCAGGGAGGC
TGCCATTGTGGACCCTGTGCAGCCCCAGAAGGTTGTAGAAACCGTGAGAAAGTATGGTGTGAAG
CTGACCACGGTGCTCACCACACACCACCACTGGGACCACGCTGGCGGGAACGAGAAGCTGGTCA
AGCTGCAGCCAGGGCTGAAGGTGTATGGGGGTGACGACCGTATCGGGGCCCTGACTCACAAAGT
CACGCACCTGTTCACTCTGCAGGTGGGGAGTCTCCATGTTAAATGCTTATCAACCCCCTGCCAC
ACCTCAGGACACATCTGTTACTTGGTGAGCAAGCCTGGTGGTCCAGATCCCCCTGCTGTGTTCA
CAGGTGACACCCTGTTTGTGGCCGGCTGTGGGAAGTTCTATGAAGGGACTGCAGAAGAGATGTA
TAGAGCACTGCTGGAGGTCCTGGGCCGGCTCCCTCCAGACACAAAAGTCTACTGTGGCCATGAG
TACACCATCAGCAACCTCAAGTTCGCACGCCACGTGGAGCCCAGCAACACTGCTGTTCTGGAGA
AGCTGGCCTGGGCCAAGGAGAAATATGCCACTGGGGAGCCCACGGTGCCATCCACCATCGCTGA
GGAGTTCACCTACAACCCCTTCATGAGAGTGAGGGAGAAGACGGTGCAGCAGCATGCCGGCCAG
ACTGACCCCGTGGCCACCATGCGCTACATCCGCAGGGAGAAGGACCAGTTCAAGTTGGAAGCTG
TCATTCATCAGTCTGCCAAACCATGCCAAGTGGGGATTCTGGGAAGAAGGCTTCCCCCAAGGTC
GGGCAGGAGTCAGAACCTGGAGGATCCAGCAGAGCCTGGCCTGGGACTGGTGACAGCAAGAGGT
TGGCCCTGCCTCCACACTCCCTCCCCAGTGCTGTTCCCTCTGATCCAGTGATCCATCCCTCAGC
AGTCACCTCTGCTCAGAAGAAGGGTCACTCTGCTCAGACCCACACATGCCTGGGAGTCCACTGA
CAGCAGAGGCAGGACACGAGATCCCTTCTCTGCCTCCTCGCCACCTCGGGGTCAGAGTTCATTT
GCAGCCGGGTATGGTGGTGTGCACCTGCAATCCCCGTGACTTGGGGGGCTGAGGCGGGA

hide sequence

RefSeq Acc Id:

XM_040276868 ⟹ XP_040132802

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	104,515,477 - 104,527,785 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005337876	(Get FASTA)	NCBI Sequence Viewer
	XP_005337877	(Get FASTA)	NCBI Sequence Viewer
	XP_013219529	(Get FASTA)	NCBI Sequence Viewer
	XP_013219530	(Get FASTA)	NCBI Sequence Viewer
	XP_021590635	(Get FASTA)	NCBI Sequence Viewer
	XP_040132802	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000008167.2
	ENSSTOP00000026847.1
	ENSSTOP00000027580.1
GenBank Protein	KAG3258941	(Get FASTA)	NCBI Sequence Viewer
	KAG3258942	(Get FASTA)	NCBI Sequence Viewer
	KAG3258943	(Get FASTA)	NCBI Sequence Viewer
	KAG3258944	(Get FASTA)	NCBI Sequence Viewer
	KAG3258945	(Get FASTA)	NCBI Sequence Viewer
	KAG3258946	(Get FASTA)	NCBI Sequence Viewer
	KAG3258947	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_013219530 ⟸ XM_013364076

- Peptide Label:

isoform X4

- Sequence:

show sequence

MVLGRRLFGCRSLAALGVACARRGLGPALLGTLLYYTDLRKSLTVEQSAMKVELLPALTDNYMY
LIIDKDTREAAIVDPVQPQKVVETVRKYGVKLTTVLTTHHHWDHAGGNEKLVKLQPGLKVYGGD
DRIGALTHKVTHLFTLQVTPCLWPAVGSSMKGLQKRCIEHCWRSWAGSLQTQKSTVAMSTPSAT
SSSHATWSPATLLFWRSWPGPRRNMPLGSPRCHPPSLRSSPTTPS

hide sequence

RefSeq Acc Id:	XP_005337876 ⟸ XM_005337819
- Peptide Label:	isoform X1
- UniProtKB:	I3MCY4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVLGRRLFGCRSLAALGVACARRGLGPALLGTLLYYTDLRKSLTVEQSAMKVELLPALTDNYMY LIIDKDTREAAIVDPVQPQKVVETVRKYGVKLTTVLTTHHHWDHAGGNEKLVKLQPGLKVYGGD DRIGALTHKVTHLFTLQVGSLHVKCLSTPCHTSGHICYLVSKPGGPDPPAVFTGDTLFVAGCGK FYEGTAEEMYRALLEVLGRLPPDTKVYCGHEYTISNLKFARHVEPSNTAVLEKLAWAKEKYATG EPTVPSTIAEEFTYNPFMRVREKTVQQHAGQTDPVATMRYIRREKDQFKVPPD hide sequence

RefSeq Acc Id:

XP_005337877 ⟸ XM_005337820

- Peptide Label:

isoform X2

- Sequence:

show sequence

MVLGRRLFGCRSLAALGVACARRGLDLRKSLTVEQSAMKVELLPALTDNYMYLIIDKDTREAAI
VDPVQPQKVVETVRKYGVKLTTVLTTHHHWDHAGGNEKLVKLQPGLKVYGGDDRIGALTHKVTH
LFTLQVGSLHVKCLSTPCHTSGHICYLVSKPGGPDPPAVFTGDTLFVAGCGKFYEGTAEEMYRA
LLEVLGRLPPDTKVYCGHEYTISNLKFARHVEPSNTAVLEKLAWAKEKYATGEPTVPSTIAEEF
TYNPFMRVREKTVQQHAGQTDPVATMRYIRREKDQFKLEAVIHQSAKPCQVGILGRRLPPRSGR
SQNLEDPAEPGLGLVTARGWPCLHTPSPVLFPLIQ

hide sequence

RefSeq Acc Id:	XP_013219529 ⟸ XM_013364075
- Peptide Label:	isoform X3
- UniProtKB:	A0A287D247 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKVELLPALTDNYMYLIIDKDTREAAIVDPVQPQKVVETVRKYGVKLTTVLTTHHHWDHAGGNE KLVKLQPGLKVYGGDDRIGALTHKVTHLFTLQVGSLHVKCLSTPCHTSGHICYLVSKPGGPDPP AVFTGDTLFVAGCGKFYEGTAEEMYRALLEVLGRLPPDTKVYCGHEYTISNLKFARHVEPSNTA VLEKLAWAKEKYATGEPTVPSTIAEEFTYNPFMRVREKTVQQHAGQTDPVATMRYIRREKDQFK LEAVIHQSAKPCQVGILGRRLPPRSGRSQNLEDPAEPGLGLVTARGWPCLHTPSPVLFPLIQ hide sequence

RefSeq Acc Id:	XP_021590635 ⟸ XM_021734960
- Peptide Label:	isoform X3
- UniProtKB:	A0A287D247 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKVELLPALTDNYMYLIIDKDTREAAIVDPVQPQKVVETVRKYGVKLTTVLTTHHHWDHAGGNE KLVKLQPGLKVYGGDDRIGALTHKVTHLFTLQVGSLHVKCLSTPCHTSGHICYLVSKPGGPDPP AVFTGDTLFVAGCGKFYEGTAEEMYRALLEVLGRLPPDTKVYCGHEYTISNLKFARHVEPSNTA VLEKLAWAKEKYATGEPTVPSTIAEEFTYNPFMRVREKTVQQHAGQTDPVATMRYIRREKDQFK LEAVIHQSAKPCQVGILGRRLPPRSGRSQNLEDPAEPGLGLVTARGWPCLHTPSPVLFPLIQ hide sequence

RefSeq Acc Id:	XP_040132802 ⟸ XM_040276868
- Peptide Label:	isoform X3
- UniProtKB:	A0A287D247 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000026847 ⟸ ENSSTOT00000031316

RefSeq Acc Id:

ENSSTOP00000008167 ⟸ ENSSTOT00000009110

RefSeq Acc Id:

ENSSTOP00000027580 ⟸ ENSSTOT00000039131

Protein Domains

Hydroxyacylglutathione hydrolase C-terminal Metallo-beta-lactamase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000009109	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000009110.3	UniProtKB/TrEMBL
	ENSSTOT00000031316.1	UniProtKB/TrEMBL
	ENSSTOT00000039131.1	UniProtKB/TrEMBL
Gene3D-CATH	3.60.15.10	UniProtKB/TrEMBL
InterPro	Clx_II_MBL	UniProtKB/TrEMBL
	HAGH_C	UniProtKB/TrEMBL
	Hydroxyacylglutathione_Hdrlase	UniProtKB/TrEMBL
	Metallo-B-lactamas	UniProtKB/TrEMBL
	RibonucZ/Hydroxyglut_hydro	UniProtKB/TrEMBL
NCBI Gene	Hagh	ENTREZGENE
PANTHER	BETA LACTAMASE DOMAIN	UniProtKB/TrEMBL
	HYDROXYACYLGLUTATHIONE HYDROLASE, MITOCHONDRIAL	UniProtKB/TrEMBL
Pfam	HAGH_C	UniProtKB/TrEMBL
	Lactamase_B	UniProtKB/TrEMBL
PIRSF	Glx	UniProtKB/TrEMBL
SMART	Lactamase_B	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56281	UniProtKB/TrEMBL
UniProt	A0A287CZV8_ICTTR	UniProtKB/TrEMBL
	A0A287D247	ENTREZGENE, UniProtKB/TrEMBL
	I3MCY4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB