Padi1 (peptidyl arginine deiminase 1) - Rat Genome Database

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Gene: Padi1 (peptidyl arginine deiminase 1) Ictidomys tridecemlineatus
Analyze
Symbol: Padi1
Name: peptidyl arginine deiminase 1
RGD ID: 12640032
Description: ENCODES a protein that exhibits protein-arginine deiminase activity (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC101971867; peptidyl arginine deiminase, type I; protein-arginine deiminase type-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,282,998 - 38,338,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364744,134,737 - 4,161,958 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364744,121,948 - 4,163,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Padi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,282,998 - 38,338,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364744,134,737 - 4,161,958 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364744,121,948 - 4,163,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PADI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,205,128 - 17,246,007 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,205,128 - 17,246,007 (+)EnsemblGRCh38hg38GRCh38
GRCh37117,531,623 - 17,572,502 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,404,208 - 17,445,088 (+)NCBINCBI36Build 36hg18NCBI36
Build 34117,276,935 - 17,316,654NCBI
Celera115,854,608 - 15,895,194 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,775,640 - 15,816,163 (+)NCBIHuRef
CHM1_1117,640,028 - 17,680,932 (+)NCBICHM1_1
T2T-CHM13v2.0117,016,414 - 17,057,242 (+)NCBIT2T-CHM13v2.0
Padi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,540,292 - 140,573,089 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,540,294 - 140,573,089 (-)EnsemblGRCm39 Ensembl
GRCm384140,812,981 - 140,845,778 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4140,812,983 - 140,845,778 (-)EnsemblGRCm38mm10GRCm38
MGSCv374140,368,896 - 140,401,693 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,085,057 - 140,117,854 (-)NCBIMGSCv36mm8
Celera4142,625,585 - 142,659,167 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map472.62NCBI
Padi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,402,614 - 158,435,077 (-)NCBIGRCr8
mRatBN7.25153,119,566 - 153,152,034 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,119,566 - 153,152,034 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5155,808,770 - 155,842,124 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,583,072 - 157,615,507 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,571,691 - 157,604,213 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,338,850 - 159,371,313 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,338,850 - 159,371,313 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,045,278 - 163,077,738 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,671,725 - 159,704,188 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,681,912 - 159,714,376 (-)NCBI
Celera5151,477,068 - 151,509,531 (-)NCBICelera
Cytogenetic Map5q36NCBI
Padi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,610,064 - 1,642,379 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,610,643 - 1,641,953 (-)NCBIChiLan1.0ChiLan1.0
PADI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21209,883,230 - 209,923,725 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,002,081 - 209,042,579 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,150,407 - 16,190,901 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1117,205,538 - 17,245,972 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,205,452 - 17,245,972 (+)Ensemblpanpan1.1panPan2
PADI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1280,997,563 - 81,036,942 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl280,996,021 - 81,036,942 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,533,555 - 77,574,493 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,643,691 - 81,684,606 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,643,693 - 81,689,788 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,396,618 - 78,437,587 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,412,393 - 79,453,539 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,482,086 - 80,523,026 (-)NCBIUU_Cfam_GSD_1.0
PADI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,830,046 - 75,871,911 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,830,053 - 75,871,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2670,173,382 - 70,214,300 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PADI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,341,430 - 115,388,234 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,343,203 - 115,381,634 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666033731,523 - 778,340 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000000819   ⟹   ENSSTOP00000000733
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364744,134,737 - 4,161,958 (+)Ensembl
RefSeq Acc Id: XM_040289152   ⟹   XP_040145086
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505838,282,998 - 38,338,780 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040145086 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000000733.3
Reference Protein Sequences
RefSeq Acc Id: XP_040145086   ⟸   XM_040289152
RefSeq Acc Id: ENSSTOP00000000733   ⟸   ENSSTOT00000000819
Protein Domains
Protein-arginine deiminase (PAD) central   Protein-arginine deiminase (PAD) N-terminal   Protein-arginine deiminase C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000816 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000819.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1700 UniProtKB/TrEMBL
  2.60.40.1860 UniProtKB/TrEMBL
InterPro Cupredoxin UniProtKB/TrEMBL
  PAD UniProtKB/TrEMBL
  PAD_C UniProtKB/TrEMBL
  PAD_central_sf UniProtKB/TrEMBL
  PAD_N UniProtKB/TrEMBL
  PAD_N_sf UniProtKB/TrEMBL
  Prot_Arg_deaminase_cen_dom UniProtKB/TrEMBL
NCBI Gene LOC101971867 ENTREZGENE
PANTHER PROTEIN-ARGININE DEIMINASE TYPE-1 UniProtKB/TrEMBL
  PTHR10837 UniProtKB/TrEMBL
Pfam PAD UniProtKB/TrEMBL
  PAD_M UniProtKB/TrEMBL
  PAD_N UniProtKB/TrEMBL
PIRSF Protein-arginine_deiminase UniProtKB/TrEMBL
Superfamily-SCOP Pentein UniProtKB/TrEMBL
  SSF110083 UniProtKB/TrEMBL
  SSF49503 UniProtKB/TrEMBL
UniProt I3LXE4_ICTTR UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-13 Padi1  peptidyl arginine deiminase 1  LOC101971867  protein-arginine deiminase type-1  Symbol and/or name change 5135510 APPROVED