Tnks2 (tankyrase 2) - Rat Genome Database

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Gene: Tnks2 (tankyrase 2) Ictidomys tridecemlineatus
Analyze
Symbol: Tnks2
Name: tankyrase 2
RGD ID: 12564431
Description: ENCODES a protein that exhibits enzyme binding (inferred); glycosyltransferase activity (inferred); NAD+ ADP-ribosyltransferase activity (inferred); INVOLVED IN multicellular organism growth (ortholog); regulation of multicellular organism growth (ortholog); telomere maintenance (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (inferred); nuclear envelope (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: poly [ADP-ribose] polymerase tankyrase-2; tankyrase-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721341,142,964 - 41,205,100 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366012,776,345 - 2,837,707 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366012,776,338 - 2,837,703 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Tnks2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721341,142,964 - 41,205,100 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366012,776,345 - 2,837,707 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366012,776,338 - 2,837,703 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNKS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381091,798,426 - 91,865,475 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1091,798,426 - 91,865,475 (+)EnsemblGRCh38hg38GRCh38
GRCh371093,558,183 - 93,625,232 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361093,548,049 - 93,615,012 (+)NCBINCBI36Build 36hg18NCBI36
Build 341093,548,048 - 93,615,012NCBI
Celera1087,301,773 - 87,368,904 (+)NCBICelera
Cytogenetic Map10q23.32NCBI
HuRef1087,186,894 - 87,254,191 (+)NCBIHuRef
CHM1_11093,839,907 - 93,906,988 (+)NCBICHM1_1
T2T-CHM13v2.01092,681,611 - 92,748,788 (+)NCBIT2T-CHM13v2.0
Tnks2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391936,811,583 - 36,870,877 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1936,811,632 - 36,870,877 (+)EnsemblGRCm39 Ensembl
GRCm381936,834,129 - 36,893,477 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1936,834,232 - 36,893,477 (+)EnsemblGRCm38mm10GRCm38
MGSCv371936,908,722 - 36,967,967 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361936,832,583 - 36,958,617 (+)NCBIMGSCv36mm8
Celera1937,609,652 - 37,668,932 (+)NCBICelera
Cytogenetic Map19C2NCBI
cM Map1931.96NCBI
Tnks2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81243,980,432 - 244,033,629 (+)NCBIGRCr8
mRatBN7.21234,567,888 - 234,621,079 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1234,567,858 - 234,621,079 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,957,470 - 243,010,368 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01249,885,628 - 249,938,508 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,723,807 - 242,776,700 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01255,478,794 - 255,532,143 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1255,479,261 - 255,532,143 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1255,479,261 - 255,532,143 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01262,953,201 - 263,006,973 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41241,112,141 - 241,164,804NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11241,253,368 - 241,345,984NCBI
Celera1231,660,758 - 231,713,638NCBICelera
Cytogenetic Map1q53NCBI
Tnks2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554251,417,679 - 1,492,267 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554251,419,013 - 1,492,267 (-)NCBIChiLan1.0ChiLan1.0
TNKS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28103,837,790 - 103,903,675 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110103,843,094 - 103,908,990 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01088,547,396 - 88,612,973 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11092,070,362 - 92,134,911 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1092,070,362 - 92,134,911 (+)Ensemblpanpan1.1panPan2
TNKS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1286,286,125 - 6,354,284 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl286,285,690 - 6,352,317 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha286,462,048 - 6,530,287 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0286,540,024 - 6,608,295 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl286,539,063 - 6,608,204 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1286,266,668 - 6,334,898 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0286,299,503 - 6,367,799 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0286,463,794 - 6,532,479 (+)NCBIUU_Cfam_GSD_1.0
TNKS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14103,396,459 - 103,461,821 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114103,396,424 - 103,461,830 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214112,909,835 - 112,975,236 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNKS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1985,074,228 - 85,140,761 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl985,074,667 - 85,143,054 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604845,805,170 - 45,871,377 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnks2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247373,059,265 - 3,136,105 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247373,059,222 - 3,136,104 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013362149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010002273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000002357   ⟹   ENSSTOP00000002108
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366012,776,345 - 2,837,707 (-)Ensembl
RefSeq Acc Id: XM_013362149   ⟹   XP_013217603
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721341,142,964 - 41,205,100 (-)NCBI
SpeTri2.0NW_0049366012,776,338 - 2,837,703 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013217603 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000002108.3
GenBank Protein KAG3264496 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013217603   ⟸   XM_013362149
- UniProtKB: I3M092 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000002108   ⟸   ENSSTOT00000002357
Protein Domains
PARP catalytic   SAM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002349 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000002357.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  3.90.228.10 UniProtKB/TrEMBL
  6.20.320.10 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Poly(ADP-ribose)pol_cat_dom UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
NCBI Gene Tnks2 ENTREZGENE
PANTHER M-PHASE PHOSPHOPROTEIN 8 UniProtKB/TrEMBL
  MYOTROPHIN UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
  PARP UniProtKB/TrEMBL
  SAM_2 UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  PARP_CATALYTIC UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
Superfamily-SCOP ADP-ribosylation UniProtKB/TrEMBL
  SSF47769 UniProtKB/TrEMBL
  SSF48403 UniProtKB/TrEMBL
UniProt I3M092 ENTREZGENE, UniProtKB/TrEMBL