Otud3 (OTU deubiquitinase 3) - Rat Genome Database

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Gene: Otud3 (OTU deubiquitinase 3) Ictidomys tridecemlineatus
Analyze
Symbol: Otud3
Name: OTU deubiquitinase 3
RGD ID: 12562376
Description: ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); INVOLVED IN negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); protein stabilization (ortholog); ASSOCIATED WITH 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (ortholog); chromosome 1p36 deletion syndrome (ortholog); congenital disorder of glycosylation Ir (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: OTU deubiquitinase 3, transcript variant X1; OTU deubiquitinase 3, transcript variant X2; OTU domain containing 3; OTU domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505840,169,259 - 40,182,347 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364745,994,076 - 6,011,799 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364745,994,019 - 6,010,101 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Otud3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505840,169,259 - 40,182,347 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364745,994,076 - 6,011,799 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364745,994,019 - 6,010,101 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTUD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38119,882,395 - 19,912,945 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl119,882,395 - 19,912,945 (+)EnsemblGRCh38hg38GRCh38
GRCh37120,208,888 - 20,239,438 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36120,081,475 - 20,112,025 (+)NCBINCBI36Build 36hg18NCBI36
Celera118,535,727 - 18,566,275 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef118,454,515 - 18,485,063 (+)NCBIHuRef
CHM1_1120,318,433 - 20,348,979 (+)NCBICHM1_1
T2T-CHM13v2.0119,705,780 - 19,736,328 (+)NCBIT2T-CHM13v2.0
Otud3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394138,618,374 - 138,641,322 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4138,622,690 - 138,641,256 (-)EnsemblGRCm39 Ensembl
GRCm384138,891,063 - 138,914,026 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4138,895,379 - 138,913,945 (-)EnsemblGRCm38mm10GRCm38
MGSCv374138,451,294 - 138,469,862 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364138,167,028 - 138,194,561 (-)NCBIMGSCv36mm8
Celera4140,681,791 - 140,700,203 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.57NCBI
Otud3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,419,099 - 156,445,341 (-)NCBIGRCr8
mRatBN7.25151,135,826 - 151,162,207 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,140,059 - 151,163,560 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5153,837,429 - 153,859,585 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,611,737 - 155,633,893 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,593,646 - 155,615,802 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,346,286 - 157,368,450 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,346,286 - 157,368,472 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05161,086,486 - 161,108,351 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45157,718,629 - 157,741,095 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5149,525,815 - 149,547,300 (-)NCBICelera
Cytogenetic Map5q36NCBI
Otud3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955452487,994 - 516,217 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955452488,295 - 516,162 (+)NCBIChiLan1.0ChiLan1.0
OTUD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21207,206,462 - 207,238,251 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11206,323,313 - 206,355,107 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,836,697 - 18,867,568 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1119,888,492 - 19,911,040 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl119,880,667 - 19,905,857 (+)Ensemblpanpan1.1panPan2
OTUD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1278,843,627 - 78,875,215 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl278,847,177 - 78,875,121 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha275,357,183 - 75,388,674 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,410,480 - 79,441,987 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,415,377 - 79,442,142 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,229,387 - 76,260,582 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,236,287 - 77,267,770 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,307,247 - 78,338,718 (-)NCBIUU_Cfam_GSD_1.0
OTUD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl678,241,624 - 78,273,539 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1678,241,604 - 78,273,544 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
OTUD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120112,642,979 - 112,673,435 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20112,648,143 - 112,672,819 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660333,507,292 - 3,537,289 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Otud3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247644,949,975 - 4,976,067 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247644,950,727 - 4,979,856 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000022570   ⟹   ENSSTOP00000018542
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364745,994,076 - 6,011,799 (+)Ensembl
RefSeq Acc Id: XM_021733903   ⟹   XP_021589578
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505840,169,261 - 40,182,347 (+)NCBI
SpeTri2.0NW_0049364745,994,019 - 6,010,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021733907   ⟹   XP_021589582
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505840,169,259 - 40,182,347 (+)NCBI
SpeTri2.0NW_0049364745,994,160 - 6,010,101 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021589578 (Get FASTA)   NCBI Sequence Viewer  
  XP_021589582 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000018542.2
GenBank Protein KAG3282298 (Get FASTA)   NCBI Sequence Viewer  
  KAG3282299 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021589578   ⟸   XM_021733903
- Peptide Label: isoform X1
- UniProtKB: I3N2E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021589582   ⟸   XM_021733907
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSTOP00000018542   ⟸   ENSSTOT00000022570
Protein Domains
OTU


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000019922 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000022570.2 UniProtKB/TrEMBL
Gene3D-CATH 3.90.70.80 UniProtKB/TrEMBL
InterPro OTU_dom UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/TrEMBL
NCBI Gene Otud3 ENTREZGENE
PANTHER OTU DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
  OTU DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
Pfam OTU UniProtKB/TrEMBL
PROSITE OTU UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
UniProt I3N2E6 ENTREZGENE, UniProtKB/TrEMBL