Mrgprf (MAS related GPR family member F)

Gene: Mrgprf (MAS related GPR family member F) Ictidomys tridecemlineatus

Analyze

Symbol:

Mrgprf

Name:

MAS related GPR family member F

RGD ID:

12549491

Description:

ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN membrane (inferred); nuclear membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

mas-related G-protein coupled receptor member F

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	4,919,441 - 4,926,928 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	1,361,823 - 1,369,300 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936599	1,361,858 - 1,369,277 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 3 (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IEA)

Cellular Component

membrane (IEA)

nuclear membrane (IEA)

plasma membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Mrgprf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	4,919,441 - 4,926,928 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	1,361,823 - 1,369,300 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936599	1,361,858 - 1,369,277 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MRGPRF
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	69,004,398 - 69,013,633 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	69,004,398 - 69,013,246 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	68,771,866 - 68,780,714 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	68,771,862 - 68,780,850 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	68,528,442 - 68,537,311	NCBI
Celera	11	66,111,592 - 66,120,578 (-)	NCBI		Celera
Cytogenetic Map	11	q13.3	NCBI
HuRef	11	65,111,051 - 65,120,036 (-)	NCBI		HuRef
CHM1_1	11	68,655,094 - 68,664,084 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	69,014,626 - 69,023,860 (-)	NCBI		T2T-CHM13v2.0

Mrgprf
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	144,854,646 - 144,863,294 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	144,854,565 - 144,863,294 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	145,300,909 - 145,309,557 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	145,300,828 - 145,309,557 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	152,486,814 - 152,495,462 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	145,110,299 - 145,118,947 (+)	NCBI		MGSCv36	mm8
Celera	7	145,068,810 - 145,077,498 (+)	NCBI		Celera
Cytogenetic Map	7	F5	NCBI
cM Map	7	89.05	NCBI

Mrgprf
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	209,893,384 - 209,902,852 (+)	NCBI		GRCr8
mRatBN7.2	1	200,464,100 - 200,473,588 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	200,463,973 - 200,473,660 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	208,839,505 - 208,848,971 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	215,926,053 - 215,935,521 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	208,600,265 - 208,609,733 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	218,465,642 - 218,476,228 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	218,466,289 - 218,476,224 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	225,334,082 - 225,344,027 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	205,750,528 - 205,759,996 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	205,903,980 - 205,912,991 (+)	NCBI
Celera	1	198,018,612 - 198,028,080 (+)	NCBI		Celera
Cytogenetic Map	1	q42	NCBI

Mrgprf
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	16,950,136 - 16,958,623 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	16,950,136 - 16,957,971 (+)	NCBI	ChiLan1.0	ChiLan1.0

MRGPRF
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	69,963,160 - 69,972,597 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	70,999,791 - 71,015,471 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	64,090,299 - 64,103,063 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	67,391,018 - 67,403,745 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	67,391,018 - 67,403,746 (-)	Ensembl	panpan1.1		panPan2

MRGPRF
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	49,006,789 - 49,015,080 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	49,006,888 - 49,015,080 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	47,614,138 - 47,622,328 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	49,681,469 - 49,689,779 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	49,681,575 - 49,689,779 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	49,127,505 - 49,135,689 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	48,713,846 - 48,722,033 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	49,460,520 - 49,468,710 (+)	NCBI		UU_Cfam_GSD_1.0

MRGPRF
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	4,123,829 - 4,132,938 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	4,123,786 - 4,132,938 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

MRGPRF
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	5,559,186 - 5,569,839 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	5,563,977 - 5,568,959 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	102,842,174 - 102,851,394 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mrgprf
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	17,972,076 - 17,980,047 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	17,971,523 - 17,979,956 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005333315	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040283991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000010943 ⟹ ENSSTOP00000009816

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936599	1,361,823 - 1,369,300 (+)	Ensembl

RefSeq Acc Id:

XM_005333315 ⟹ XP_005333372

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	4,919,441 - 4,926,928 (+)	NCBI
SpeTri2.0	NW_004936599	1,361,858 - 1,369,277 (+)	NCBI

Sequence:

show sequence

CCTCCACCAAGCTCACGTTCCCGAGGCTCGGGCAGCGCTTGGCTGGCCTGCTGCCCTGCTGGGT
CCGCCAGGCGGAGGCAGGGATCTCAGGAGGAGCCCGTCACAAAGGGAAGGACTCCGAGGACCAG
GACAGCGGCAGGTGCCAGGTGGGCGTGCCAGCCGGTGAGCTGCGAGCAGGGACCTGGACCCTCC
GAGCCTGGAGATGGCTGGGAACTGCTCCTGGGAGGCCCATGCCACCAGCAGGAACAAGATGTGT
CCCGGCCTGAGCGAGGCCCCGGAGCTCTACAGCCGCGGCTTCCTGACCATCGAGCAGATCGCCA
TGCTGCCCCCGCCGGCCGTCATGAACTACATCTTCCTGCTGCTCTGCCTGTGCGGCCTGGTGGG
CAACGGGCTGGTCCTCTGGTTTTTCGGCTTCTCCATCAAGAGGACCCCCTTCTCCACCTACTTC
CTGCACCTGGCCAGCGCCGACAGCGCTTACCTCTTCAGCAAGGCCCTGTTCTCCCTCCTGAACG
CGGGGGCCTTTCTGGGCACCTTCGCCGACTTCGTCCGCAGCGTGTCCCGGGTCGTGGGGCTCTG
CGCCTTCGTTGGCGGCGTGAGCCTCCTGCCGGCCATCAGCACAGAGCGCAGTGTGTCCGTCATC
TTTCCTGCCTGGTACTGGCGCCGGCGGCCCAAGCGCCTGTCGGCCGTGGTGTGCGCCCTGCTCT
GGCTCCTGTCCCTGCTGGTCACTGGAATTCACAACTACTTCTGTGTGTTCCTGGGCCACGCAGA
CTCCGGGGCAGCCTGCAGGCACATGGACATCGCCCTGGGCATCATCCTCTTCCTGGTCTTCTGC
CCACTCATGGTGCTGCCCTGCCTGGCCCTCATCTTGCACGTGGAGTGCCGGGCACGGAGGCGCC
AGCGGTCAGCCAAACTCAACCACGTGGTGCTGGCCATGGTCTCCGTCTTCCTCGTGTCCTCCAT
CTACTTGGGGATCGACTGGTTCCTCTTCTGGGTCTTCCAGATCCCGGCCCCGTTCCCCGAGTAC
GTCACCGACCTGTGCATCTGCATCAACAGCAGTGCCAAGCCCATGGTCTACTTCCTGGCCGGGA
GGGACAAGTCGCAGCGGCTGTGGGAGCCTCTCAGGGTGGTCTTCCAGAGGGCCCTGAGGGACGG
CGCCGAGCTGGGGGAGGCTGCAGGCGGCACGCCCAACACGGTCACCATGGAGATGCAGTGCCCC
TCTGGGAATGCCTCCTGAGAGGCCTGCGACGTGGACCCTGGCCTCCAGAGACTCTTTGCCACCG
ACAGGAACAGGCACCTGCCTCGGTGCCCGCGTGGGAGGACCATCTGGCTCGGCCCCTCCTGCCT
CCTTCTCCCAGGGATGGAGGCCCTGGGGGTGGCCAAGAGGCCGAGCAGCCACCAGCACCCCCAG
CCACTCTGCCTCAGTGACCCACGATACCAAAGTCACCCCACGCGGTGGGGCCCTCCTCGCCCTG
GGCTGGTCGGCACAGGGGAGGAGGTGGCCGCAGCCCCGCCACCTCCTGCCCTACAGCCTCGTCC
CCAGGGGTGGACTGCTCTCGAGATTCCGTCCCCAGGGCGGAGCATGAGCTGACCTGAACCCAAC
GGTGCTACCTGGGAGAGGTGTCCCTTCATGGCCTTGCAGCCAGATCTTTCTGCAAACAACATCC
CTGTCCCCTTGGTGAGTCAGTTGGTGACTTTAATGGGGAAACGCCTGGCCCTGGGGCCACTCGA
GACCGGAAGGACGGCCTTTTCTAACTCTGTGCCTGGCCAGCCCTGGGCAGCCTCCCAAGCACTC
TGTGTCCTCCAGGCCACTGTGGACCATATGGGCAGTTCCTGGACCGAGTCCCTGGGCTCTAGCA
CCACCCAGAAGTGGGCTCTGGCTCTGTCCTGTCGCCTGGGGACTGGCACTGTGGTGCCCAACAA
GCACAGTGGCCCCATGTAGCCACAGGGAGTTCTGTAAGACAATGAAGTGTCACCAATAAACGTT
TTGTACCTTGCCGCGAGGCAGGCTGAA

hide sequence

RefSeq Acc Id:

XM_040283991 ⟹ XP_040139925

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	4,920,964 - 4,926,928 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005333372	(Get FASTA)	NCBI Sequence Viewer
	XP_040139925	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000009816.2
GenBank Protein	KAG3284476	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005333372 ⟸ XM_005333315

- UniProtKB:

I3MGE2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGNCSWEAHATSRNKMCPGLSEAPELYSRGFLTIEQIAMLPPPAVMNYIFLLLCLCGLVGNGL
VLWFFGFSIKRTPFSTYFLHLASADSAYLFSKALFSLLNAGAFLGTFADFVRSVSRVVGLCAFV
GGVSLLPAISTERSVSVIFPAWYWRRRPKRLSAVVCALLWLLSLLVTGIHNYFCVFLGHADSGA
ACRHMDIALGIILFLVFCPLMVLPCLALILHVECRARRRQRSAKLNHVVLAMVSVFLVSSIYLG
IDWFLFWVFQIPAPFPEYVTDLCICINSSAKPMVYFLAGRDKSQRLWEPLRVVFQRALRDGAEL
GEAAGGTPNTVTMEMQCPSGNAS

hide sequence

RefSeq Acc Id:	XP_040139925 ⟸ XM_040283991
- UniProtKB:	I3MGE2 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000009816 ⟸ ENSSTOT00000010943

Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000010947	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000010943.3	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	MRGPCRF	UniProtKB/TrEMBL
	MRGPCRFAMILY	UniProtKB/TrEMBL
NCBI Gene	Mrgprf	ENTREZGENE
PANTHER	PTHR11334	UniProtKB/TrEMBL
	PTHR11334:SF3	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	MRGPCRF	UniProtKB/TrEMBL
	MRGPCRFAMILY	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	I3MGE2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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