Tssc4 (tumor suppressing subtransferable candidate 4)

Gene: Tssc4 (tumor suppressing subtransferable candidate 4) Ictidomys tridecemlineatus

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Symbol:

Tssc4

Name:

tumor suppressing subtransferable candidate 4

RGD ID:

12543057

Description:

ENCODES a protein that exhibits molecular sequestering activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN spliceosomal snRNP assembly (ortholog); spliceosomal tri-snRNP complex assembly (ortholog); ASSOCIATED WITH delta beta-thalassemia (ortholog); developmental and epileptic encephalopathy (ortholog); early infantile epileptic encephalopathy (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); U5 snRNP (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	2,728,961 - 2,730,504 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936794	672,123 - 673,703 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

delta beta-thalassemia (ISO)

developmental and epileptic encephalopathy (ISO)

early infantile epileptic encephalopathy (ISO)

genetic disease (ISO)

neuronal ceroid lipofuscinosis (ISO)

Segawa Syndrome, Autosomal Recessive (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

spliceosomal snRNP assembly (ISO)

spliceosomal tri-snRNP complex assembly (ISO)

Cellular Component

cytoplasm (ISO)

nucleus (ISO)

U5 snRNP (ISO)

Molecular Function

molecular sequestering activity (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

References

Genomics

Comparative Map Data

Tssc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	2,728,961 - 2,730,504 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936794	672,123 - 673,703 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TSSC4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	2,400,750 - 2,403,876 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	2,400,488 - 2,403,878 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	2,421,980 - 2,425,106 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	2,380,099 - 2,381,682 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	2,380,098 - 2,381,681	NCBI
Celera	11	2,458,330 - 2,459,913 (+)	NCBI		Celera
Cytogenetic Map	11	p15.5	NCBI
HuRef	11	2,213,876 - 2,215,459 (+)	NCBI		HuRef
CHM1_1	11	2,422,397 - 2,423,980 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	2,490,101 - 2,493,227 (+)	NCBI		T2T-CHM13v2.0

Tssc4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	142,621,049 - 142,624,830 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	142,622,986 - 142,624,830 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	143,068,416 - 143,071,093 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	143,069,249 - 143,071,093 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	150,255,273 - 150,256,992 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	142,878,758 - 142,880,477 (+)	NCBI		MGSCv36	mm8
Celera	7	142,824,973 - 142,826,692 (+)	NCBI		Celera
Cytogenetic Map	7	F5	NCBI
cM Map	7	88.11	NCBI

Tssc4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	207,681,420 - 207,684,244 (+)	NCBI		GRCr8
mRatBN7.2	1	198,251,986 - 198,254,810 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	198,235,487 - 198,254,980 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	206,631,736 - 206,633,435 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	213,717,792 - 213,719,491 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	206,391,949 - 206,393,648 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	216,253,786 - 216,256,610 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	216,254,979 - 216,256,608 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	223,115,417 - 223,118,241 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	203,344,569 - 203,346,200 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	203,498,021 - 203,499,651 (+)	NCBI
Celera	1	195,822,009 - 195,823,708 (+)	NCBI		Celera
Cytogenetic Map	1	q42	NCBI

Tssc4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	14,175,271 - 14,178,991 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	14,175,271 - 14,178,991 (+)	NCBI	ChiLan1.0	ChiLan1.0

TSSC4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	4,809,768 - 4,813,261 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	4,021,465 - 4,024,958 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	2,424,217 - 2,427,602 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	2,452,388 - 2,455,772 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	2,452,388 - 2,455,772 (+)	Ensembl	panpan1.1		panPan2

TSSC4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	46,476,168 - 46,478,651 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	46,477,427 - 46,478,389 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	45,085,415 - 45,087,946 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	47,155,352 - 47,157,884 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	47,156,660 - 47,157,622 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	46,603,262 - 46,605,793 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	46,183,862 - 46,186,394 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	46,930,903 - 46,933,435 (+)	NCBI		UU_Cfam_GSD_1.0

TSSC4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	1,643,006 - 1,645,858 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	1,642,693 - 1,645,860 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TSSC4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	2,215,375 - 2,218,808 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	99,414,753 - 99,420,184 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tssc4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	15,212,435 - 15,215,585 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	15,211,125 - 15,214,712 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005340400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005340400 ⟹ XP_005340457

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	2,728,961 - 2,730,504 (+)	NCBI
SpeTri2.0	NW_004936794	672,123 - 673,703 (+)	NCBI

Sequence:

show sequence

CGGAGGCGGCGGACGCGCCAGTGTGCCGGGCTCCGGCGAGTTCCCGGTCGGCCCTCTGAGTGCC
GGAGGCTGCGAGTCCGCCGCGCTCCTGCCGCCCTGCGTTTCGCGCGGCCCAGCGGAGCGGAGCA
GAGCAGAGGCCGCTGCTCGGCCCACCCGCGGAGCGGTCCCCGAGCGAGGCAGGCAGCCGCCGAG
AGCCCGGCCCTCGGCGGGTTGCACCGTGGTCTGGTGGCCGGCTCTGCTGCAGCCCTCGCCCAGC
GAGCAGCCGCGCACCTGGGCCGGGGCCCGCACGCCCCCCACCGAGGCCCTTCATCGGCCCTCCG
CGGGGCAGGGGGCTCGCGGCAGGCCGGACAGGGGCCCCCGGAGGACGCGGGTCTGCGGGAGCGC
CTCGTTCTGAACACGCTCTTCACGGGCAAACCGCTGGCCGCGGGGCTCCAGGGCAGCGCGGCCG
GGCGCCCATGGCTGAGGCGGGGGCGGGCGAGCCGGCCCCTGGCTTGGAGGCGGAGCAGGCGACA
GAGTATGACACCCTGCCTTCTGACACCGTCTCGCTCAGCGACTCGGACTCAGACCTCAGTTTGC
CCGGCGCTGCTGAGGTGGAGGCGCTGTCCCCCGAGGACTCCGGCCCCGAAGAGCCCCCCTGGTC
CCCGGCAGGCCTCCCCGGCGCCGCCGCGCAGCCCTTCCTCCTCAAAGGCGTGAGCTCCACCTTC
TCCCAGCGAAGCCACAGCATCTTTGACTGTCTGGAGGGGGCGGCCAGGCGGGTGCCCACCTCGG
CAGCTCACACCAGCAGGAGTGACAGCGGTGGCCCCCAGCGGCCACCGATGCCCTCGAGCCAGCC
TCCGGCGGCAGACCCTGACCCTCCGAGGGTGCCGCCTCTCCCTGACTATGTGGCTCACCCTGAG
CGCTGGACCAAGTACAGCCTGGAAGACGTGGCCGAGGCCAGCGAGCAGAGCAACCGGGCAGCCG
CCCGGGCCTTCCTGGGCTCGCGCAGCCGGGCGGCCCCCGCCGACTACACGCCCTCCTTCAACCA
GCGCCCCTCCAGCGGTGGGGAGGGGAGAGTCCTCTTCACCAAGCCCGTCCGAGCTGGAGAGGCC
AGAGCTGAGAGGAAGAGGGCCCTGAAGAAGGGGGGTGTGCCAGGTGTTGGGGGCGAGGGTCCCG
TGGAGCTGGCCCACCTGGTGGGGCTTGGGAGCCCAGAGGCCGAGGAGTGTGGTAGTGCCCTGGG
GCTACAGGATCTGGGGACACCTTCAGGGGCTGTCCACCCTGGGTCCTCACCGGGACCCCCAGGG
GTGGAGATGGTTGGTTTCCATGGCAGCAAGAAGCGGAGCCGAGAGCACCTGCGCAATAGGGGCA
GCAGCCCTGATAGCTCAGGGGCTGGGATGGGAGGGGGACACTCAGACTGACCACACTGCCATTG
CCTGCCTGCCTGCCCAAGCAGAGACTGCTGAGTGGGCTGGAGTATGGGGCCATGGTTGCTAGGG
TGGATGGGGAATCATCCTCTTGGTAAGGAAGTTGATTAGCTGCCTGGAGGAGGTGTCAGAGTTC
TGGCTACCCAGTGTCCATGGGGGGACAATAAAAGTTTTGGCTGTT

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Protein Sequences


Protein RefSeqs	XP_005340457	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	KAG3284423	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005340457 ⟸ XM_005340400

- Sequence:

show sequence

MAEAGAGEPAPGLEAEQATEYDTLPSDTVSLSDSDSDLSLPGAAEVEALSPEDSGPEEPPWSPA
GLPGAAAQPFLLKGVSSTFSQRSHSIFDCLEGAARRVPTSAAHTSRSDSGGPQRPPMPSSQPPA
ADPDPPRVPPLPDYVAHPERWTKYSLEDVAEASEQSNRAAARAFLGSRSRAAPADYTPSFNQRP
SSGGEGRVLFTKPVRAGEARAERKRALKKGGVPGVGGEGPVELAHLVGLGSPEAEECGSALGLQ
DLGTPSGAVHPGSSPGPPGVEMVGFHGSKKRSREHLRNRGSSPDSSGAGMGGGHSD

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Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Tssc4	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar