Amph (amphiphysin) - Rat Genome Database

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Gene: Amph (amphiphysin) Ictidomys tridecemlineatus
Analyze
Symbol: Amph
Name: amphiphysin
RGD ID: 12535183
Description: ENCODES a protein that exhibits phosphatase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN learning (ortholog); positive regulation of endocytosis (ortholog); positive regulation of GTPase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN axon terminus (ortholog); extrinsic component of synaptic vesicle membrane (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: amphiphysin, transcript variant X1; amphiphysin, transcript variant X2; amphiphysin, transcript variant X3; amphiphysin, transcript variant X4; amphiphysin, transcript variant X5; amphiphysin, transcript variant X6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511894,747,942 - 94,972,174 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647813,960,771 - 14,183,764 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647813,959,669 - 14,183,835 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Amph
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511894,747,942 - 94,972,174 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647813,960,771 - 14,183,764 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647813,959,669 - 14,183,835 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AMPH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38738,383,704 - 38,631,373 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl738,383,704 - 38,631,420 (-)EnsemblGRCh38hg38GRCh38
GRCh37738,423,305 - 38,670,973 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36738,389,830 - 38,637,545 (-)NCBINCBI36Build 36hg18NCBI36
Build 34738,196,545 - 38,444,260NCBI
Celera738,411,134 - 38,658,846 (-)NCBICelera
Cytogenetic Map7p14.1NCBI
HuRef738,307,292 - 38,555,371 (-)NCBIHuRef
CHM1_1738,425,940 - 38,673,786 (-)NCBICHM1_1
T2T-CHM13v2.0738,540,588 - 38,788,026 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2738,460,969 - 38,708,834 (-)NCBI
Amph
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391319,132,524 - 19,335,089 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1319,132,375 - 19,335,091 (+)EnsemblGRCm39 Ensembl
GRCm381318,948,142 - 19,154,032 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1318,948,205 - 19,150,921 (+)EnsemblGRCm38mm10GRCm38
MGSCv371319,040,240 - 19,242,784 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361318,955,836 - 19,158,380 (+)NCBIMGSCv36mm8
Celera1319,259,525 - 19,457,406 (+)NCBICelera
Cytogenetic Map13A2NCBI
cM Map136.89NCBI
Amph
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81750,435,018 - 50,678,583 (-)NCBIGRCr8
mRatBN7.21745,739,385 - 45,982,905 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1745,739,395 - 45,983,315 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1748,180,900 - 48,690,815 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01752,949,166 - 53,178,746 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01747,057,349 - 47,292,588 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01748,304,324 - 48,562,838 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1748,304,322 - 48,562,905 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01746,357,604 - 46,621,763 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41753,558,804 - 53,802,936NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11753,561,655 - 53,805,777NCBI
Cytogenetic Map17q11NCBI
Amph
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554604,804,442 - 5,023,202 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554604,804,400 - 5,024,312 (+)NCBIChiLan1.0ChiLan1.0
LOC100995139
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2643,214,846 - 43,461,235 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1791,539,581 - 91,785,970 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0739,015,699 - 39,262,120 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1739,250,081 - 39,495,844 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl739,250,081 - 39,495,844 (-)Ensemblpanpan1.1panPan2
AMPH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11811,132,078 - 11,261,847 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1811,143,446 - 11,260,841 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1810,903,625 - 11,114,792 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01811,099,548 - 11,310,938 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1811,098,056 - 11,309,936 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11811,076,355 - 11,287,485 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01811,044,639 - 11,263,972 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01811,160,063 - 11,371,410 (+)NCBIUU_Cfam_GSD_1.0
AMPH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9108,799,793 - 108,971,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19108,800,718 - 108,971,575 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29119,651,630 - 119,751,221 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Amph
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474022,399,244 - 22,614,608 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474022,399,302 - 22,615,736 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000012277   ⟹   ENSSTOP00000011003
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647813,960,771 - 14,183,764 (-)Ensembl
RefSeq Acc Id: XM_021722289   ⟹   XP_021577964
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511894,747,942 - 94,972,174 (-)NCBI
SpeTri2.0NW_00493647813,959,669 - 14,183,834 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040291850   ⟹   XP_040147784
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511894,747,942 - 94,972,174 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021577964   ⟸   XM_021722289
- Peptide Label: isoform X1
- UniProtKB: I3MIV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040147784   ⟸   XM_040291850
- Peptide Label: isoform X2
- UniProtKB: I3MIV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000011003   ⟸   ENSSTOT00000012277
Protein Domains
BAR   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000012263 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000012277.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/TrEMBL
  Amphiphysin UniProtKB/TrEMBL
  Amphiphysin_1 UniProtKB/TrEMBL
  Amphiphysin_I_SH3 UniProtKB/TrEMBL
  BAR_dom UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene Amph ENTREZGENE
PANTHER AMPHIPHYSIN UniProtKB/TrEMBL
  PTHR46514:SF2 UniProtKB/TrEMBL
Pfam BAR UniProtKB/TrEMBL
PRINTS AMPHIPHYSIN UniProtKB/TrEMBL
  AMPHIPHYSIN1 UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
PROSITE BAR UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART BAR UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt I3MIV4 ENTREZGENE, UniProtKB/TrEMBL