Wasf1 (WASP family member 1) - Rat Genome Database

Name: Wasf1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Wasf1 (WASP family member 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Wasf1

Name:

WASP family member 1

RGD ID:

12511601

Description:

ENCODES a protein that exhibits protein kinase A binding (ortholog); small GTPase binding (ortholog); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); dendrite extension (ortholog); dendritic transport of mitochondrion (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Generalized Epilepsy (ortholog); genetic disease (ortholog); FOUND IN mitochondrial outer membrane (ortholog); mitochondrion (ortholog); postsynapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

WAS protein family member 1; WAS protein family member 1, transcript variant X1; WAS protein family member 1, transcript variant X2; WAS protein family member 1, transcript variant X3; wiskott-Aldrich syndrome protein family member 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	WASF1 (WASP family member 1)	NCBI	Ortholog
Mus musculus (house mouse):	Wasf1 (WASP family, member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Wasf1 (WASP family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Wasf1 (WASP family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	WASF1 (WASP family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	WASF1 (WASP family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	WASF1 (WASP family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	WASF1 (WASP family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Wasf1 (WASP family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	101,761,273 - 101,821,206 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936564	6,036,135 - 6,096,046 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Generalized Epilepsy (ISO)

genetic disease (ISO)

intellectual disability (ISO)

NEURODEVELOPMENTAL DISORDER WITH ABSENT LANGUAGE AND VARIABLE SEIZURES (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (IEA)

cellular response to brain-derived neurotrophic factor stimulus (ISO)

dendrite extension (ISO)

dendritic transport of mitochondrion (ISO)

lamellipodium morphogenesis (ISO)

mitochondrion organization (ISO)

modification of postsynaptic actin cytoskeleton (ISO)

neuron projection development (ISO)

positive regulation of Arp2/3 complex-mediated actin nucleation (IEA)

positive regulation of neurotrophin TRK receptor signaling pathway (ISO)

Rac protein signal transduction (ISO)

receptor-mediated endocytosis (ISO)

Cellular Component

anchoring junction (IEA)

cytoplasm (IEA)

cytoskeleton (IEA)

focal adhesion (IEA)

lamellipodium (IEA)

mitochondrial outer membrane (ISO)

mitochondrion (ISO)

postsynapse (ISO)

protein-containing complex (ISO)

SCAR complex (IEA)

synapse (IEA)

Molecular Function

actin binding (IEA)

Arp2/3 complex binding (IEA)

protein binding (ISO)

protein kinase A binding (ISO)

protein kinase A regulatory subunit binding (IEA)

small GTPase binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Wasf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	101,761,273 - 101,821,206 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936564	6,036,135 - 6,096,046 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

WASF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	110,099,819 - 110,179,670 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	110,099,819 - 110,180,004 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	110,421,022 - 110,500,873 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	110,527,715 - 110,607,900 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	110,527,714 - 110,606,609	NCBI
Celera	6	111,167,684 - 111,247,873 (-)	NCBI		Celera
Cytogenetic Map	6	q21	NCBI
HuRef	6	107,987,658 - 108,067,845 (-)	NCBI		HuRef
CHM1_1	6	110,684,246 - 110,764,410 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	111,278,252 - 111,358,111 (-)	NCBI		T2T-CHM13v2.0

Wasf1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	40,759,476 - 40,814,565 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	40,759,471 - 40,814,566 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	40,883,480 - 40,938,569 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	40,883,475 - 40,938,570 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	40,603,340 - 40,658,375 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	40,571,988 - 40,626,982 (+)	NCBI		MGSCv36	mm8
Celera	10	41,779,631 - 41,834,540 (+)	NCBI		Celera
Cytogenetic Map	10	B1	NCBI
cM Map	10	22.07	NCBI

Wasf1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	45,908,458 - 45,956,118 (+)	NCBI		GRCr8
mRatBN7.2	20	44,325,815 - 44,372,999 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	44,325,795 - 44,372,996 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	46,110,330 - 46,157,484 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	45,769,485 - 45,816,639 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	46,492,179 - 46,541,494 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	48,456,191 - 48,503,768 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	48,455,705 - 48,503,898 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	50,107,711 - 50,155,913 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	20	45,130,786 - 45,177,385 (+)	NCBI		Celera
Cytogenetic Map	20	q12	NCBI

Wasf1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	34,889,566 - 34,965,769 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	34,893,287 - 34,966,670 (-)	NCBI	ChiLan1.0	ChiLan1.0

WASF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	130,117,370 - 130,204,116 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	128,003,292 - 128,090,041 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	107,911,751 - 107,988,821 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	111,951,725 - 112,058,554 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	111,951,726 - 111,979,329 (-)	Ensembl	panpan1.1		panPan2

WASF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	66,833,776 - 66,897,500 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	66,833,995 - 66,897,483 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	66,653,278 - 66,717,426 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	67,717,606 - 67,781,968 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	67,717,613 - 67,781,602 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	67,069,337 - 67,133,320 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	66,915,644 - 66,979,778 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	67,187,405 - 67,251,555 (-)	NCBI		UU_Cfam_GSD_1.0

WASF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	1	76,107,595 - 76,180,335 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	85,590,358 - 85,660,191 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

WASF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	63,718,784 - 63,793,024 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	63,718,737 - 63,793,151 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	36,004,710 - 36,077,937 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Wasf1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624916	1,181,234 - 1,201,975 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624916	1,183,291 - 1,301,925 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005330162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021729729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021729730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040283206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005330162 ⟹ XP_005330219

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	101,761,273 - 101,820,854 (-)	NCBI
SpeTri2.0	NW_004936564	6,036,135 - 6,095,705 (-)	NCBI

Sequence:

show sequence

TGTTCGCTCGCGCATCGAACACATCGTGGGTCCGGCGACCGGCAGGCGCCCTAGGCGGCATTCC
TGGTGGCCCGGCGCTTCAGCCGCTACTCGAAGCGGGTTCCGCCCCGGAGCCCGACGCTCTTGTG
GGCTGCAGGTGGAGTCCCCGAGCTGAGCGGGACCGGCGGCCGCCGCCGAAGCATGAAGAAGGGG
TAAGGCTAGAGCCCCCCACGATTTCACGGTGAACTAGCACAGAGGTTTATCTCAAGATGCCGTT
AGTGAAAAGAAACATCGATCCTAGGCACTTGTGCCACACAGCACTGCCTAGAGGCATTAAGAAC
GAACTGGAATGTGTAACCAATATTTCTTTGGCAAATATAATTAGACAGCTAAGTAGCCTAAGTA
AATATGCTGAAGATATATTTGGAGAATTATTCAATGAAGCACATAGTTTTTCCTTCAGAGTTAA
CTCACTGCAAGAACGTGTGGACCGTTTATCTGTTAGTGTTACACAGCTTGATCCTAAAGAAGAA
GAATTGTCTTTGCAAGACATAACAATGAGAAAAGCCTTCCGAAGTTCTACAATTCAAGATCAGC
AGCTTTTCGACCGCAAGACTTTGCCTATTCCATTACAAGAGACATATGATGTTTGTGAACAACC
TCCACCTCTCAACATACTTACTCCTTATAGAGATGATGGTAAAGAAGGTTTGAAGTTTTATACC
AATCCTTCATATTTCTTTGATCTATGGAAAGAAAAAATGTTGCAAGATACAGAGGACAAGAGGA
AGGAAAAGAGGAAACAGAAGCAGAAAAATCTAGATCGTCCTCATGAACCAGAAAAAGTGCCAAG
AGCACCTCATGACAGGAGGAGAGAATGGCAGAAGCTGGCCCAAGGTCCAGAGCTGGCTGAAGAT
GATGCTAATCTCTTACATAAGCATATTGAAGTTGCTAATGGCCCAGCCTCTCATTTTGAAACAA
GACCTCAGACTTACGTGGATCATATGGATGGATCTTATTCACTTTCTGCCTTGCCATTTAGTCA
GATGAGTGAGCTTCTGACTAGAGCTGAGGAAAGGGTCTTAGTCAGACCACATGAACCACCTCCG
CCTCCACCCATGCATGGAACAGGAGATGCAAAACCCATACCCACCTGTATCAGTTCTGCTACAG
GTTTGATAGAAAATCGCCCTCAGTCACCAGCCACAGGCAGAACACCTGTGTTTGTGAGCCCCAC
TCCCCCACCTCCTCCACCACCTCTTCCATCTGCCTTGTCAACTTCTTCATTAAGAGCTTCAATG
ACTTCCACTCCTCCCCCTCCAGTACCTCCCCCACCTCCACCTCCAACCACTGCTTTGCAAGCTC
CAGCTGTACCACCACCTCCAGCTCCTCTTCAGATTGCCCCTGGAGTTCTTCACCCAGCTCCTCC
TCCAATTGCACCTCCTCTAGTACAACCCTCTCCACCAGTAGCTAGAGCTGCCCCAGTATGTGAG
ACTGTACCAGTTCATCCACTCCCACAAGGTGAAGTCCAGGGGCTGCCTCCACCCCCACCACCGC
CTCCTCTGCCTCCACCTGGCATTCGACCATCATCAGCTGTCACAGTTGCAGCTCTTGCTCATCC
TCCCTCTGGGCTACATCCAACACCATCTACTGCCCCAGGTCCCCATGTTCCATTAATGCCTCCA
TCTCCTCCATCACAAGTTATACCTGCTTCTGAGCCAAAGCGTCATCCATCAACCCTACCTGTAA
TCAGTGACGCAAGGAGTGTACTACTGGAAGCAATACGAAAAGGTATTCAACTACGCAAAGTAGA
AGAGCAGCGTGAACAGGAAGCTAAGCATGAACGCATTGAAAATGATGTTGCCACCATCCTGTCT
CGCCGTATTGCTGTGGAATATAGTGATTCAGAAGATGATTCAGAATTTGATGAAGTAGATTGGT
TGGAATAAGAAAAATGCATTGATCAATATTACAAAACTGAATGCAAATGTCCTTTGTGGTGCTT
GTTCTTTGAAAATGTTTGGTCATTCTAGTGTTTTGCTTTCTATTCCTTATAATAAATAACCCTT
TTCCTCCATAATTTTTGATTTTGAAGAAAAGTATTAGCATACATTTCAAACTAAATGTTTTACA
GTGGCTTATATTTTTTTTCCCTGAAAAGACATAATTTGGTCCAACAAACCACTAAGTATTAAGC
ATGGACAGCTGTTGTTAGAGTAGCAGATTCAGTTTTTTGATATATCTTAATTGTGCACTTCGTG
AATTTTAATTTAAGGAAAGCGAATGAGATTGAAATCTTGAGGGCAGCTGTAATATTAATGAGCC
TTATTCTACTTCCTGATGTTTTAAAAGAAGAAACACTGCCTTGATATATGAATACACTCAGAAA
GTACATTTAGCTTGTAGTGTTGAATTCTCTTAAAGGAATGCTTAAATTTTTTATTATTATTTTA
TTGTTTTAAATACTTGCCTTATTTGAATGTTTAGCAGTACTCCTTTCCCACTTATATATTGTGT
GATACAATTTTGCTTGCCTATAGGAGTTTAAAAATTTTCCATGTGAAATACTCTGAATTAAACA
TACATGTAACTTACATAACTGTTAGAAATAACAGTCTGATTTAATAAATGTTTCATTTTAAAGG
TTC

hide sequence

RefSeq Acc Id:

XM_021729729 ⟹ XP_021585404

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	101,761,273 - 101,821,206 (-)	NCBI
SpeTri2.0	NW_004936564	6,036,136 - 6,096,046 (-)	NCBI

Sequence:

show sequence

ACGGTTCTCTCCGTCCCCCTCCCCCAAACTAAGGATTGGGTAATACCACAGAGCCTCAGGAAAG
GGGGAAGAGCGATCTTCGCCCCCTATGATGGGTGAACTAGCACAGAGGTTTATCTCAAGATGCC
GTTAGTGAAAAGAAACATCGATCCTAGGCACTTGTGCCACACAGCACTGCCTAGAGGCATTAAG
AACGAACTGGAATGTGTAACCAATATTTCTTTGGCAAATATAATTAGACAGCTAAGTAGCCTAA
GTAAATATGCTGAAGATATATTTGGAGAATTATTCAATGAAGCACATAGTTTTTCCTTCAGAGT
TAACTCACTGCAAGAACGTGTGGACCGTTTATCTGTTAGTGTTACACAGCTTGATCCTAAAGAA
GAAGAATTGTCTTTGCAAGACATAACAATGAGAAAAGCCTTCCGAAGTTCTACAATTCAAGATC
AGCAGCTTTTCGACCGCAAGACTTTGCCTATTCCATTACAAGAGACATATGATGTTTGTGAACA
ACCTCCACCTCTCAACATACTTACTCCTTATAGAGATGATGGTAAAGAAGGTTTGAAGTTTTAT
ACCAATCCTTCATATTTCTTTGATCTATGGAAAGAAAAAATGTTGCAAGATACAGAGGACAAGA
GGAAGGAAAAGAGGAAACAGAAGCAGAAAAATCTAGATCGTCCTCATGAACCAGAAAAAGTGCC
AAGAGCACCTCATGACAGGAGGAGAGAATGGCAGAAGCTGGCCCAAGGTCCAGAGCTGGCTGAA
GATGATGCTAATCTCTTACATAAGCATATTGAAGTTGCTAATGGCCCAGCCTCTCATTTTGAAA
CAAGACCTCAGACTTACGTGGATCATATGGATGGATCTTATTCACTTTCTGCCTTGCCATTTAG
TCAGATGAGTGAGCTTCTGACTAGAGCTGAGGAAAGGGTCTTAGTCAGACCACATGAACCACCT
CCGCCTCCACCCATGCATGGAACAGGAGATGCAAAACCCATACCCACCTGTATCAGTTCTGCTA
CAGGTTTGATAGAAAATCGCCCTCAGTCACCAGCCACAGGCAGAACACCTGTGTTTGTGAGCCC
CACTCCCCCACCTCCTCCACCACCTCTTCCATCTGCCTTGTCAACTTCTTCATTAAGAGCTTCA
ATGACTTCCACTCCTCCCCCTCCAGTACCTCCCCCACCTCCACCTCCAACCACTGCTTTGCAAG
CTCCAGCTGTACCACCACCTCCAGCTCCTCTTCAGATTGCCCCTGGAGTTCTTCACCCAGCTCC
TCCTCCAATTGCACCTCCTCTAGTACAACCCTCTCCACCAGTAGCTAGAGCTGCCCCAGTATGT
GAGACTGTACCAGTTCATCCACTCCCACAAGGTGAAGTCCAGGGGCTGCCTCCACCCCCACCAC
CGCCTCCTCTGCCTCCACCTGGCATTCGACCATCATCAGCTGTCACAGTTGCAGCTCTTGCTCA
TCCTCCCTCTGGGCTACATCCAACACCATCTACTGCCCCAGGTCCCCATGTTCCATTAATGCCT
CCATCTCCTCCATCACAAGTTATACCTGCTTCTGAGCCAAAGCGTCATCCATCAACCCTACCTG
TAATCAGTGACGCAAGGAGTGTACTACTGGAAGCAATACGAAAAGGTATTCAACTACGCAAAGT
AGAAGAGCAGCGTGAACAGGAAGCTAAGCATGAACGCATTGAAAATGATGTTGCCACCATCCTG
TCTCGCCGTATTGCTGTGGAATATAGTGATTCAGAAGATGATTCAGAATTTGATGAAGTAGATT
GGTTGGAATAAGAAAAATGCATTGATCAATATTACAAAACTGAATGCAAATGTCCTTTGTGGTG
CTTGTTCTTTGAAAATGTTTGGTCATTCTAGTGTTTTGCTTTCTATTCCTTATAATAAATAACC
CTTTTCCTCCATAATTTTTGATTTTGAAGAAAAGTATTAGCATACATTTCAAACTAAATGTTTT
ACAGTGGCTTATATTTTTTTTCCCTGAAAAGACATAATTTGGTCCAACAAACCACTAAGTATTA
AGCATGGACAGCTGTTGTTAGAGTAGCAGATTCAGTTTTTTGATATATCTTAATTGTGCACTTC
GTGAATTTTAATTTAAGGAAAGCGAATGAGATTGAAATCTTGAGGGCAGCTGTAATATTAATGA
GCCTTATTCTACTTCCTGATGTTTTAAAAGAAGAAACACTGCCTTGATATATGAATACACTCAG
AAAGTACATTTAGCTTGTAGTGTTGAATTCTCTTAAAGGAATGCTTAAATTTTTTATTATTATT
TTATTGTTTTAAATACTTGCCTTATTTGAATGTTTAGCAGTACTCCTTTCCCACTTATATATTG
TGTGATACAATTTTGCTTGCCTATAGGAGTTTAAAAATTTTCCATGTGAAATACTCTGAATTAA
ACATACATGTAACTTACATAACTGTTAGAAATAACAGTCTGATTTAATAAATGTTTCATTTTAA
AGGTT

hide sequence

RefSeq Acc Id:

XM_021729730 ⟹ XP_021585405

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	101,761,273 - 101,820,754 (-)	NCBI
SpeTri2.0	NW_004936564	6,036,136 - 6,095,547 (-)	NCBI

Sequence:

show sequence

GACCGGCGGCCGCCGCCGAAGCATGAAGAAGGGGTAAGGCTAGAGCCCCCCACGATTTCACGGT
GAACTAGCACAGAGGTTTATCTCAAGATGCCGTTAGTGAAAAGAAACATCGATCCTAGGCACTT
GTGCCACACAGCACTGCCTAGAGGCATTAAGAACGAACTGGAATGTGTAACCAATATTTCTTTG
GCAAATATAATTAGACAGCTAAGTAGCCTAAGTAAATATGCTGAAGATATATTTGGAGAATTAT
TCAATGAAGCACATAGTTTTTCCTTCAGAGTTAACTCACTGCAAGAACGTGTGGACCGTTTATC
TGTTAGTGTTACACAGCTTGATCCTAAAGAAGAAGAATTGTCTTTGCAAGACATAACAATGAGA
AAAGCCTTCCGAAGTTCTACAATTCAAGATCAGCAGCTTTTCGACCGCAAGACTTTGCCTATTC
CATTACAAGAGACATATGATGTTTGTGAACAACCTCCACCTCTCAACATACTTACTCCTTATAG
AGATGATGGTAAAGAAGGTTTGAAGTTTTATACCAATCCTTCATATTTCTTTGATCTATGGAAA
GAAAAAATGTTGCAAGATACAGAGGACAAGAGGAAGGAAAAGAGGAAACAGAAGAAAAATCTAG
ATCGTCCTCATGAACCAGAAAAAGTGCCAAGAGCACCTCATGACAGGAGGAGAGAATGGCAGAA
GCTGGCCCAAGGTCCAGAGCTGGCTGAAGATGATGCTAATCTCTTACATAAGCATATTGAAGTT
GCTAATGGCCCAGCCTCTCATTTTGAAACAAGACCTCAGACTTACGTGGATCATATGGATGGAT
CTTATTCACTTTCTGCCTTGCCATTTAGTCAGATGAGTGAGCTTCTGACTAGAGCTGAGGAAAG
GGTCTTAGTCAGACCACATGAACCACCTCCGCCTCCACCCATGCATGGAACAGGAGATGCAAAA
CCCATACCCACCTGTATCAGTTCTGCTACAGGTTTGATAGAAAATCGCCCTCAGTCACCAGCCA
CAGGCAGAACACCTGTGTTTGTGAGCCCCACTCCCCCACCTCCTCCACCACCTCTTCCATCTGC
CTTGTCAACTTCTTCATTAAGAGCTTCAATGACTTCCACTCCTCCCCCTCCAGTACCTCCCCCA
CCTCCACCTCCAACCACTGCTTTGCAAGCTCCAGCTGTACCACCACCTCCAGCTCCTCTTCAGA
TTGCCCCTGGAGTTCTTCACCCAGCTCCTCCTCCAATTGCACCTCCTCTAGTACAACCCTCTCC
ACCAGTAGCTAGAGCTGCCCCAGTATGTGAGACTGTACCAGTTCATCCACTCCCACAAGGTGAA
GTCCAGGGGCTGCCTCCACCCCCACCACCGCCTCCTCTGCCTCCACCTGGCATTCGACCATCAT
CAGCTGTCACAGTTGCAGCTCTTGCTCATCCTCCCTCTGGGCTACATCCAACACCATCTACTGC
CCCAGGTCCCCATGTTCCATTAATGCCTCCATCTCCTCCATCACAAGTTATACCTGCTTCTGAG
CCAAAGCGTCATCCATCAACCCTACCTGTAATCAGTGACGCAAGGAGTGTACTACTGGAAGCAA
TACGAAAAGGTATTCAACTACGCAAAGTAGAAGAGCAGCGTGAACAGGAAGCTAAGCATGAACG
CATTGAAAATGATGTTGCCACCATCCTGTCTCGCCGTATTGCTGTGGAATATAGTGATTCAGAA
GATGATTCAGAATTTGATGAAGTAGATTGGTTGGAATAAGAAAAATGCATTGATCAATATTACA
AAACTGAATGCAAATGTCCTTTGTGGTGCTTGTTCTTTGAAAATGTTTGGTCATTCTAGTGTTT
TGCTTTCTATTCCTTATAATAAATAACCCTTTTCCTCCATAATTTTTGATTTTGAAGAAAAGTA
TTAGCATACATTTCAAACTAAATGTTTTACAGTGGCTTATATTTTTTTTCCCTGAAAAGACATA
ATTTGGTCCAACAAACCACTAAGTATTAAGCATGGACAGCTGTTGTTAGAGTAGCAGATTCAGT
TTTTTGATATATCTTAATTGTGCACTTCGTGAATTTTAATTTAAGGAAAGCGAATGAGATTGAA
ATCTTGAGGGCAGCTGTAATATTAATGAGCCTTATTCTACTTCCTGATGTTTTAAAAGAAGAAA
CACTGCCTTGATATATGAATACACTCAGAAAGTACATTTAGCTTGTAGTGTTGAATTCTCTTAA
AGGAATGCTTAAATTTTTTATTATTATTTTATTGTTTTAAATACTTGCCTTATTTGAATGTTTA
GCAGTACTCCTTTCCCACTTATATATTGTGTGATACAATTTTGCTTGCCTATAGGAGTTTAAAA
ATTTTCCATGTGAAATACTCTGAATTAAACATACATGTAACTTACATAACTGTTAGAAATAACA
GTCTGATTTAATAAATGTTTCATTTTAAAGGTT

hide sequence

RefSeq Acc Id:

XM_040283206 ⟹ XP_040139140

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	101,761,273 - 101,820,761 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005330219	(Get FASTA)	NCBI Sequence Viewer
	XP_021585404	(Get FASTA)	NCBI Sequence Viewer
	XP_021585405	(Get FASTA)	NCBI Sequence Viewer
	XP_040139140	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000005327.2
	ENSSTOP00000031635.1
GenBank Protein	KAG3290051	(Get FASTA)	NCBI Sequence Viewer
	KAG3290052	(Get FASTA)	NCBI Sequence Viewer
	KAG3290053	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005330219 ⟸ XM_005330162
- Peptide Label:	isoform X1
- UniProtKB:	I3M705 (UniProtKB/TrEMBL), A0A287DDI9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSF RVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVC EQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEK VPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALP FSQMSELLTRAEERVLVRPHEPPPPPPMHGTGDAKPIPTCISSATGLIENRPQSPATGRTPVFV SPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPTTALQAPAVPPPPAPLQIAPGVLHP APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSAVTVAAL AHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLR KVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE hide sequence

RefSeq Acc Id:	XP_021585404 ⟸ XM_021729729
- Peptide Label:	isoform X1
- UniProtKB:	I3M705 (UniProtKB/TrEMBL), A0A287DDI9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSF RVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVC EQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEK VPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALP FSQMSELLTRAEERVLVRPHEPPPPPPMHGTGDAKPIPTCISSATGLIENRPQSPATGRTPVFV SPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPTTALQAPAVPPPPAPLQIAPGVLHP APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSAVTVAAL AHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLR KVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE hide sequence

RefSeq Acc Id:	XP_021585405 ⟸ XM_021729730
- Peptide Label:	isoform X2
- UniProtKB:	A0A287DDI9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSF RVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVC EQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKKNLDRPHEPEKV PRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPF SQMSELLTRAEERVLVRPHEPPPPPPMHGTGDAKPIPTCISSATGLIENRPQSPATGRTPVFVS PTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPTTALQAPAVPPPPAPLQIAPGVLHPA PPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSAVTVAALA HPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRK VEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE hide sequence

RefSeq Acc Id:	XP_040139140 ⟸ XM_040283206
- Peptide Label:	isoform X1
- UniProtKB:	I3M705 (UniProtKB/TrEMBL), A0A287DDI9 (UniProtKB/TrEMBL)

Protein Domains

WH2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000005949	UniProtKB/TrEMBL
	ENSSTOG00000031549	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000005955.3	UniProtKB/TrEMBL
	ENSSTOT00000041929.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.340	UniProtKB/TrEMBL
	6.10.280.150	UniProtKB/TrEMBL
InterPro	SCAR/WAVE_fam	UniProtKB/TrEMBL
	WH2_dom	UniProtKB/TrEMBL
NCBI Gene	Wasf1	ENTREZGENE
PANTHER	PTHR12902	UniProtKB/TrEMBL
	WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 1	UniProtKB/TrEMBL
Pfam	WH2	UniProtKB/TrEMBL
PROSITE	WH2	UniProtKB/TrEMBL
SMART	WH2	UniProtKB/TrEMBL
UniProt	A0A287DDI9	ENTREZGENE, UniProtKB/TrEMBL
	I3M705	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-02-19	Wasf1	WASP family member 1		WAS protein family member 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

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