Bzw1 (basic leucine zipper and W2 domains 1) - Rat Genome Database

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Gene: Bzw1 (basic leucine zipper and W2 domains 1) Ictidomys tridecemlineatus
Analyze
Symbol: Bzw1
Name: basic leucine zipper and W2 domains 1
RGD ID: 12499047
Description: INVOLVED IN regulation of translational initiation (ortholog); ASSOCIATED WITH melanoma (ortholog); Neurodevelopmental Disorders (ortholog); Pulmonary Arterial Hypertension (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: basic leucine zipper and W2 domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303158,179,099 - 158,195,783 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936726149,391 - 166,075 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Bzw1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303158,179,099 - 158,195,783 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936726149,391 - 166,075 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BZW1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382200,811,589 - 200,827,338 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2200,810,594 - 200,827,338 (+)EnsemblGRCh38hg38GRCh38
GRCh372201,676,312 - 201,692,061 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362201,384,892 - 201,396,805 (+)NCBINCBI36Build 36hg18NCBI36
Build 342201,502,152 - 201,514,065NCBI
Celera2195,431,568 - 195,443,290 (+)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2193,527,794 - 193,540,092 (+)NCBIHuRef
CHM1_12201,682,306 - 201,694,606 (+)NCBICHM1_1
T2T-CHM13v2.02201,295,023 - 201,310,790 (+)NCBIT2T-CHM13v2.0
Bzw1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39158,432,057 - 58,446,513 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl158,432,057 - 58,446,512 (+)EnsemblGRCm39 Ensembl
GRCm38158,392,898 - 58,407,354 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl158,392,898 - 58,407,353 (+)EnsemblGRCm38mm10GRCm38
MGSCv37158,449,980 - 58,463,392 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36158,337,682 - 58,351,094 (+)NCBIMGSCv36mm8
Celera158,912,534 - 58,924,908 (+)NCBICelera
Cytogenetic Map1C1.3NCBI
cM Map129.09NCBI
Bzw1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8967,424,860 - 67,438,656 (+)NCBIGRCr8
mRatBN7.2959,930,672 - 59,944,468 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl959,930,744 - 59,944,430 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx968,423,960 - 68,435,936 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0973,539,889 - 73,551,866 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0971,857,964 - 71,869,940 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0965,279,675 - 65,293,471 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl965,279,675 - 65,291,651 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0965,086,973 - 65,100,762 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4957,053,423 - 57,065,699 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1957,200,404 - 57,212,681 (+)NCBI
Celera957,373,337 - 57,385,338 (+)NCBICelera
Cytogenetic Map9q31NCBI
Bzw1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955403673,863 - 688,353 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955403676,384 - 688,353 (-)NCBIChiLan1.0ChiLan1.0
BZW1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213103,436,638 - 103,448,951 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B103,451,638 - 103,463,945 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B88,067,041 - 88,079,647 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B206,225,963 - 206,238,587 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B206,225,963 - 206,238,587 (+)Ensemblpanpan1.1panPan2
BZW1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13710,005,137 - 10,021,442 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3710,005,183 - 10,017,448 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3710,890,337 - 10,906,641 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0379,910,555 - 9,926,864 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1379,892,074 - 9,908,376 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0379,869,916 - 9,886,220 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0379,863,787 - 9,880,092 (+)NCBIUU_Cfam_GSD_1.0
BZW1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15104,525,451 - 104,543,783 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115104,525,900 - 104,543,795 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215115,734,058 - 115,749,664 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BZW1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11086,462,931 - 86,475,381 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1086,463,010 - 86,473,740 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040112,942,630 - 112,955,116 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bzw1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624889313,992 - 325,860 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624889314,439 - 325,885 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_040268124   ⟹   XP_040124058
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303158,179,099 - 158,195,783 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040124058 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000030784.1
GenBank Protein KAG3274950 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040124058   ⟸   XM_040268124
- UniProtKB: A0A287DB79 (UniProtKB/TrEMBL)
Protein Domains
W2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000030689 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000035216.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.180 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  W2_domain UniProtKB/TrEMBL
NCBI Gene Bzw1 ENTREZGENE
PANTHER BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam PF02020 UniProtKB/TrEMBL
PROSITE PS51363 UniProtKB/TrEMBL
SMART eIF5C UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A287DB79 ENTREZGENE, UniProtKB/TrEMBL