Ift80 (intraflagellar transport 80) - Rat Genome Database

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Gene: Ift80 (intraflagellar transport 80) Ictidomys tridecemlineatus
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Symbol: Ift80
Name: intraflagellar transport 80
RGD ID: 12491504
Description: INVOLVED IN apoptotic process (ortholog); articular cartilage development (ortholog); bone development (ortholog); ASSOCIATED WITH Asphyxia (ortholog); asphyxiating thoracic dystrophy (ortholog); asphyxiating thoracic dystrophy 1 (ortholog); FOUND IN 9+0 non-motile cilium (ortholog); intraciliary transport particle B (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: intraflagellar transport 80 homolog; intraflagellar transport 80, transcript variant X1; intraflagellar transport 80, transcript variant X2; intraflagellar transport protein 80 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560292,197,246 - 92,324,932 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936708238,268 - 362,519 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936708238,302 - 362,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (ISO)
articular cartilage development  (IEA,ISO)
bone development  (ISO)
bone mineralization involved in bone maturation  (IEA,ISO)
bone morphogenesis  (IEA,ISO)
canonical NF-kappaB signal transduction  (ISO)
cartilage development  (ISO)
cell population proliferation  (ISO)
chondrocyte differentiation  (IEA,ISO)
cilium assembly  (IEA,ISO)
endochondral ossification  (IEA,ISO)
establishment or maintenance of cell polarity  (ISO)
fibroblast growth factor receptor signaling pathway  (ISO)
gene expression  (ISO)
growth plate cartilage chondrocyte differentiation  (IEA,ISO)
growth plate cartilage development  (IEA,ISO)
keratinocyte proliferation  (IEA,ISO)
limb development  (IEA,ISO)
multicellular organism growth  (ISO)
negative regulation of keratinocyte proliferation  (IEA,ISO)
negative regulation of non-canonical Wnt signaling pathway  (IEA,ISO)
non-canonical Wnt signaling pathway  (IEA,ISO)
non-motile cilium assembly  (IEA,ISO)
odontoblast differentiation  (ISO)
odontogenesis  (ISO)
ossification  (ISO)
osteoblast differentiation  (IEA,ISO)
osteoblast proliferation  (IEA,ISO)
osteoclast differentiation  (ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
proteasomal protein catabolic process  (ISO)
protein stabilization  (ISO)
protein ubiquitination  (ISO)
receptor localization to non-motile cilium  (IEA,ISO)
skeletal system development  (IEA,ISO)
smoothened signaling pathway  (IEA,ISO)
stem cell differentiation  (ISO)
stem cell proliferation  (ISO)
tooth eruption  (ISO)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ift80
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560292,197,246 - 92,324,932 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936708238,268 - 362,519 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936708238,302 - 362,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IFT80
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383160,256,986 - 160,399,225 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3160,256,986 - 160,399,880 (-)EnsemblGRCh38hg38GRCh38
GRCh373159,974,774 - 160,117,013 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363161,457,482 - 161,600,014 (-)NCBINCBI36Build 36hg18NCBI36
Celera3158,396,141 - 158,538,687 (-)NCBICelera
Cytogenetic Map3q25.33NCBI
HuRef3157,373,426 - 157,515,902 (-)NCBIHuRef
CHM1_13159,937,988 - 160,080,209 (-)NCBICHM1_1
T2T-CHM13v2.03163,031,586 - 163,173,837 (-)NCBIT2T-CHM13v2.0
Ift80
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39368,799,832 - 68,911,939 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl368,799,832 - 68,911,892 (-)EnsemblGRCm39 Ensembl
GRCm38368,892,499 - 69,004,680 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl368,892,499 - 69,004,570 (-)EnsemblGRCm38mm10GRCm38
MGSCv37368,696,421 - 68,808,492 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36368,980,431 - 69,092,394 (-)NCBIMGSCv36mm8
Celera369,005,128 - 69,112,374 (-)NCBICelera
Cytogenetic Map3E1NCBI
cM Map332.07NCBI
Ift80
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82155,455,773 - 155,550,082 (-)NCBIGRCr8
mRatBN7.22153,144,707 - 153,240,024 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2153,145,795 - 153,240,024 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2160,275,443 - 160,369,696 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02158,325,966 - 158,420,213 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02152,958,736 - 153,052,980 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02165,506,878 - 165,600,748 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2165,505,810 - 165,600,748 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02184,867,651 - 184,961,866 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42158,892,673 - 158,987,059 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12158,842,636 - 158,937,022 (-)NCBI
Celera2147,496,487 - 147,590,825 (-)NCBICelera
Cytogenetic Map2q32NCBI
Ift80
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544810,808,940 - 10,819,655 (-)NCBIChiLan1.0ChiLan1.0
IFT80
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22158,193,564 - 158,335,974 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13158,198,280 - 158,340,492 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03157,279,076 - 157,421,478 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13165,327,511 - 165,469,795 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3165,329,056 - 165,454,905 (-)Ensemblpanpan1.1panPan2
IFT80
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13426,332,456 - 26,455,428 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3430,374,586 - 30,497,664 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03426,388,720 - 26,512,021 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3426,387,471 - 26,511,904 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13426,318,615 - 26,441,864 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03426,279,456 - 26,402,532 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03426,519,525 - 26,642,618 (-)NCBIUU_Cfam_GSD_1.0
IFT80
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1399,943,208 - 100,078,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11399,943,203 - 100,078,148 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213108,339,643 - 108,382,860 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IFT80
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11530,441,724 - 30,577,437 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1530,461,526 - 30,577,484 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660412,961,984 - 3,104,898 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ift80
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473038,003,902 - 38,144,277 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473038,003,437 - 38,144,312 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSSTOT00000024198   ⟹   ENSSTOP00000019551
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936708238,379 - 362,519 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000038521   ⟹   ENSSTOP00000030986
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936708238,268 - 348,105 (-)Ensembl
RefSeq Acc Id: XM_005338288   ⟹   XP_005338345
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560292,197,246 - 92,324,932 (-)NCBI
SpeTri2.0NW_004936708238,302 - 362,537 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735234   ⟹   XP_021590909
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560292,197,246 - 92,324,932 (-)NCBI
SpeTri2.0NW_004936708238,302 - 362,537 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040270011   ⟹   XP_040125945
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560292,197,246 - 92,324,932 (-)NCBI
RefSeq Acc Id: XM_040270012   ⟹   XP_040125946
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560292,197,246 - 92,324,911 (-)NCBI
RefSeq Acc Id: XM_040270013   ⟹   XP_040125947
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560292,197,246 - 92,324,915 (-)NCBI
RefSeq Acc Id: XP_005338345   ⟸   XM_005338288
- Peptide Label: isoform X1
- UniProtKB: I3N5A5 (UniProtKB/TrEMBL),   A0A287DBW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021590909   ⟸   XM_021735234
- Peptide Label: isoform X2
- UniProtKB: A0A287DBW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040125945   ⟸   XM_040270011
- Peptide Label: isoform X3
- UniProtKB: A0A287DBW3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040125947   ⟸   XM_040270013
- Peptide Label: isoform X4
- UniProtKB: A0A287DBW3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040125946   ⟸   XM_040270012
- Peptide Label: isoform X4
- UniProtKB: A0A287DBW3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000019551   ⟸   ENSSTOT00000024198
RefSeq Acc Id: ENSSTOP00000030986   ⟸   ENSSTOT00000038521


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000026740 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024198.2 UniProtKB/TrEMBL
  ENSSTOT00000038521.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.470 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Ift80 ENTREZGENE
PANTHER INTRAFLAGELLAR TRANSPORT PROTEIN 80 HOMOLOG UniProtKB/TrEMBL
  OUTER SEGMENT 5 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A287DBW3 ENTREZGENE, UniProtKB/TrEMBL
  I3N5A5 ENTREZGENE, UniProtKB/TrEMBL