Tmem38a (transmembrane protein 38A)

Gene: Tmem38a (transmembrane protein 38A) Ictidomys tridecemlineatus

Analyze

Symbol:

Tmem38a

Name:

transmembrane protein 38A

RGD ID:

12487337

Description:

ENCODES a protein that exhibits identical protein binding (inferred); potassium channel activity (inferred); INVOLVED IN cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); inorganic cation transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (inferred); nuclear membrane (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

trimeric intracellular cation channel type A

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	204,416,087 - 204,434,925 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936596	3,965,203 - 3,984,006 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936596	3,965,220 - 3,984,120 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to caffeine (IEA,ISO)

endoplasmic reticulum organization (IEA,ISO)

inorganic cation transmembrane transport (IEA,ISO)

monoatomic ion transport (IEA)

potassium ion transmembrane transport (IEA,ISO)

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (IEA,ISO)

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (IEA,ISO)

Cellular Component

membrane (IEA)

nuclear membrane (IEA)

nucleus (IEA)

sarcoplasmic reticulum (IEA)

Molecular Function

identical protein binding (IEA)

potassium channel activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tmem38a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	204,416,087 - 204,434,925 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936596	3,965,203 - 3,984,006 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936596	3,965,220 - 3,984,120 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM38A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	16,661,139 - 16,690,023 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	16,661,139 - 16,690,023 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	16,771,950 - 16,800,834 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	16,632,938 - 16,660,830 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	16,632,937 - 16,660,814	NCBI
Celera	19	16,673,777 - 16,701,673 (+)	NCBI		Celera
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	16,340,650 - 16,368,543 (+)	NCBI		HuRef
CHM1_1	19	16,771,437 - 16,799,382 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	16,795,931 - 16,824,815 (+)	NCBI		T2T-CHM13v2.0

Tmem38a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	73,325,033 - 73,341,128 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	73,325,899 - 73,341,126 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	72,571,189 - 72,587,284 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	72,572,055 - 72,587,282 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	75,096,002 - 75,111,183 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	75,501,092 - 75,516,273 (+)	NCBI		MGSCv36	mm8
Celera	8	76,918,441 - 76,933,607 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	35.08	NCBI

Tmem38a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	17,292,215 - 17,307,704 (-)	NCBI		GRCr8
mRatBN7.2	16	17,258,160 - 17,274,204 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	17,258,164 - 17,273,415 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	17,326,841 - 17,342,331 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	18,457,823 - 18,473,312 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	17,379,766 - 17,395,255 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	18,960,197 - 18,974,942 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	18,959,315 - 18,974,770 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	18,822,741 - 18,837,486 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	17,669,835 - 17,684,440 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	17,668,985 - 17,684,446 (-)	NCBI
Celera	16	17,478,830 - 17,493,434 (-)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

Tmem38a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955524	1,132,111 - 1,144,380 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955524	1,132,111 - 1,144,335 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM38A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	21,532,243 - 21,574,556 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	20,539,413 - 20,581,132 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	16,150,715 - 16,179,256 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	17,129,060 - 17,159,002 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	17,129,842 - 17,159,002 (+)	Ensembl	panpan1.1		panPan2

TMEM38A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	45,876,642 - 45,895,054 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	45,877,524 - 45,894,986 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	45,790,121 - 45,808,540 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	46,363,605 - 46,382,014 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	46,363,604 - 46,382,008 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	45,598,857 - 45,617,268 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	46,009,411 - 46,027,833 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	46,284,762 - 46,303,184 (-)	NCBI		UU_Cfam_GSD_1.0

TMEM38A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	60,929,049 - 60,960,467 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	60,929,043 - 60,960,527 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	60,517,874 - 60,526,926 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103234112
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	15,169,143 - 15,200,372 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	15,170,033 - 15,200,481 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	4,270,392 - 4,299,557 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem38a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624908	836,347 - 849,998 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624908	837,753 - 849,972 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005333030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000023110 ⟹ ENSSTOP00000016159

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936596	3,965,203 - 3,984,006 (-)	Ensembl

RefSeq Acc Id:

XM_005333030 ⟹ XP_005333087

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	204,416,087 - 204,434,925 (-)	NCBI
SpeTri2.0	NW_004936596	3,965,220 - 3,984,120 (-)	NCBI

Sequence:

show sequence

GCTGGGGGTGGCGCCTGGAGGGCCGGGGCGGGCCCAGCGGCGGGGGCGCAGTCGCCGGGCCGCG
GGCGGCGGGACGGACAGGGCCGGGGGCCGCGGTGGCACCCGGCGCGCGCCATGGACCTGCTGTC
GGCCCTGAGCCTGGGCGAGCTGGCGCTCAGCTTCTCACGGGTGCCGCTCTTCCCAGTCTTTGAC
CTCAGCTATTTCATCGTCTCCATTCTCTACCTCAAGTATGAACCCGGAGCGGTCGAGCTGTCCC
GGCGCCACCCGGTGGCCTCCTGGATGTGTGCCATGCTGCACTGTTTTGGGAGTTACATCCTGGC
TGACCTGCTCCTCGGGGAGCCCTTGATTGACTACTTCAGCAACAACTCCAGTGTCCTGTTGGCC
TCAGCTGTCTGGTACTTGATTTTCTTCTGCCCCCTGGACCTCTTCTACAAGTGTGTCTCCTTCC
TGCCTGTGAAGCTCATCTTCGTGGCCATGAAGGAGGTGGTGAGAGTCCGCAAGATCGCGGTGGG
CATCCATCACGCCCATCACCACTACCACCACGGGTGGTTCGTCATGATCGCAACGGGGTGGGTC
AAAGGCTCTGGGGTCGCCCTCATGTCCAACTTGGAGCAGCTGCTCCGAGGAGTCTGGAAGCCGG
AGACCAATGAGATCCTGCACATGTCCTTCCCCACCAAGGCCAGCTTGTACGGAGCCATCCTGTT
CACCCTCCAGCAGACCCGCTGGCTCCCGGTGTCCAAGGCCAGCCTCATCTTCATCTTCACCATG
TTCATGGTGTCCTGTAAGGTGTTCCTGACAGCCACTCACTCCCACAACTCCCCATTTGATGTCC
TGGAGGGCTACGTCTGCCCTGTGCTATTTGGAGCAGCCTGGGGAGGTGACCATCACCATGACAA
CCACGGTGCATCTCATGGCGGTTCCCATGGTGGCGGGCCAGGTGCCCAGCATTCCGTCCTGCCT
GCCAAGTCCAAGGAGGAGCTGAGCGAGGGCTCCAGGAAGAAGAAGACCAAGAAGGCAGATTAGG
GGGTGGCCCAGGGGACCCATGGGGCACCAGGGGTAGGACCAGGCCCAGGACCCTCACAGCTGGG
GGTCATCCTGAGCTTCTTGCCCATCTCTGGGCCTTGATTTCCCCATCTGCAAATTGGGGCCATC
AGCTCATCCTCCAGGGCTGAGGTGGGGATTAAATGAGATGACGATGGACTTTTATAGGAGTGGA
GGGTCCCTCTCTCTCTGTCAGGCCCTCTGTTGAGTCACAGCTTTTTTAGGGGCACACAGAGTCC
CGGTAGCAGCTCCAACTAAAAATCCTGGCATTTAATTCTTTGTTCTTTATTTGGTTTTGTTTTT
CTTCTCTGAAATTGCATCTTGACTCAGAGAATTTCAAGCCATGTCAAGACTTATCCTTTTGGTG
GACATTTCCTAAGTACCTGCTGTGAGCCAGGTGCTGTGATTTCAAAGTCTTCTTGCCCAGGCTC
CTCCAGGCCCAGAACTTTCTGGCTCCTGCTGGGCATCCCTGGGTAAGTTCCTTCCCTTCTCTGA
GCTTCAAGTTCCCCATCTGTAGAGTGGAGACCCCTGGCCCTCTGAACAGAAGGGCTTCTTTGAA
GCAAGACGGAAAAGATCTATAAGCTCGTCAGCACCATGCAGTCAGGAGGGGATATCAGGGCAGT
TCTGAATCGTGGAAGGATTCAAACAGCTATCTGTGGCTTCGGGCTGCCTCCAAACCAAAGACTC
GCAGCCATCTGGGTGGGGGTCCCAAGATCCAGCTCTGTGAAGGAGCTCTAGGTGCTCACAGTTG
GTCCCTGGAAGTGTCAGGCCTTCCTCATGCTGAAATCCGTCACCGTCGCTCACTCAGTCGTTCA
ACAGGCTGATGCCTGTGCTGTTTGTGCTGCTGCCGGGCAGGCCAGGAACCTGTACGGGGTGAGC
AGACTCCCTCGCCCAAGCCGAGGTCAGCAGACATCTGAGAGGGGTGGAGAGGGTGGACATGTCC
GGCCTCAGGTTGAATTTGAGCCCAGACCAGGTTGGGGTCCCGAGTGTCACCCATCTGTTGGGCA
AGTGCCTTGTTCCAGTGATGCCCGGGAGTTGGGTGGGTCCTGAGGCTTCAAGCCCCCCAATTTC
ATCCCTTGCCTGTCCGCCAAAGCTCGGCATGAGGGCCCGCCAATAAATCTGTTGTGAATGAACC
CTCA

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Protein Sequences


Protein RefSeqs	XP_005333087	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000016159.1
GenBank Protein	KAG3279984	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005333087 ⟸ XM_005333030

- UniProtKB:

I3MVL4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDLLSALSLGELALSFSRVPLFPVFDLSYFIVSILYLKYEPGAVELSRRHPVASWMCAMLHCFG
SYILADLLLGEPLIDYFSNNSSVLLASAVWYLIFFCPLDLFYKCVSFLPVKLIFVAMKEVVRVR
KIAVGIHHAHHHYHHGWFVMIATGWVKGSGVALMSNLEQLLRGVWKPETNEILHMSFPTKASLY
GAILFTLQQTRWLPVSKASLIFIFTMFMVSCKVFLTATHSHNSPFDVLEGYVCPVLFGAAWGGD
HHHDNHGASHGGSHGGGPGAQHSVLPAKSKEELSEGSRKKKTKKAD

hide sequence

RefSeq Acc Id:

ENSSTOP00000016159 ⟸ ENSSTOT00000023110

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000020542	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000023110.2	UniProtKB/TrEMBL
InterPro	TRIC_channel	UniProtKB/TrEMBL
NCBI Gene	Tmem38a	ENTREZGENE
PANTHER	PTHR12454	UniProtKB/TrEMBL
	TRIMERIC INTRACELLULAR CATION CHANNEL TYPE A	UniProtKB/TrEMBL
Pfam	TRIC	UniProtKB/TrEMBL
UniProt	I3MVL4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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