Ndufb3 (NADH:ubiquinone oxidoreductase subunit B3)

Gene: Ndufb3 (NADH:ubiquinone oxidoreductase subunit B3) Ictidomys tridecemlineatus

Analyze

Symbol:

Ndufb3

Name:

NADH:ubiquinone oxidoreductase subunit B3

RGD ID:

12484473

Description:

INVOLVED IN electron transport chain (inferred); mitochondrial respiratory chain complex I assembly (inferred); ASSOCIATED WITH Alzheimer's disease (ortholog); autoimmune lymphoproliferative syndrome type 2B (ortholog); Autoimmune Lymphoproliferative Syndrome, Type V (ortholog); FOUND IN mitochondrial respiratory chain complex I (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3; NADH:ubiquinone oxidoreductase subunit B3, transcript variant X1; NADH:ubiquinone oxidoreductase subunit B3, transcript variant X2; NADH:ubiquinone oxidoreductase subunit B3, transcript variant X3; NADH:ubiquinone oxidoreductase subunit B3, transcript variant X4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	158,368,034 - 158,379,651 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936726	338,423 - 349,943 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936726	338,384 - 349,943 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

autoimmune lymphoproliferative syndrome type 2B (ISO)

Autoimmune Lymphoproliferative Syndrome, Type V (ISO)

cataract (ISO)

common variable immunodeficiency 1 (ISO)

epilepsy (ISO)

genetic disease (ISO)

mitochondrial complex I deficiency (ISO)

Neurodevelopmental Disorders (ISO)

nuclear type mitochondrial complex I deficiency 25 (ISO)

Pulmonary Arterial Hypertension (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

electron transport chain (IEA)

mitochondrial respiratory chain complex I assembly (IEA)

Cellular Component

mitochondrial inner membrane (IEA)

mitochondrial respiratory chain complex I (IEA,ISO)

mitochondrion (IEA)

respirasome (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Ndufb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	158,368,034 - 158,379,651 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936726	338,423 - 349,943 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936726	338,384 - 349,943 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NDUFB3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	201,072,001 - 201,085,750 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	201,071,433 - 201,085,750 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	201,936,724 - 201,950,473 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	201,644,779 - 201,658,710 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	201,762,039 - 201,775,970	NCBI
Celera	2	195,691,087 - 195,705,098 (+)	NCBI		Celera
Cytogenetic Map	2	q33.1	NCBI
HuRef	2	193,787,966 - 193,801,894 (+)	NCBI		HuRef
CHM1_1	2	201,942,480 - 201,956,491 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	201,555,443 - 201,569,193 (+)	NCBI		T2T-CHM13v2.0

Ndufb3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	58,625,556 - 58,635,123 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	58,625,543 - 58,635,123 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	58,586,397 - 58,595,964 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	58,586,384 - 58,595,964 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	58,643,443 - 58,652,792 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	58,531,145 - 58,540,494 (+)	NCBI		MGSCv36	mm8
Celera	1	59,106,184 - 59,115,486 (+)	NCBI		Celera
Cytogenetic Map	1	C1.3	NCBI
cM Map	1	29.13	NCBI

Ndufb3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	67,623,417 - 67,633,629 (+)	NCBI		GRCr8
mRatBN7.2	9	60,129,240 - 60,139,452 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	60,129,154 - 60,139,446 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	68,623,673 - 68,634,023 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	73,739,618 - 73,749,968 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	72,057,879 - 72,068,231 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	65,478,496 - 65,488,708 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	65,478,496 - 65,488,702 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	65,285,887 - 65,296,099 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	57,252,769 - 57,262,981 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	57,399,754 - 57,409,928 (+)	NCBI
Celera	9	57,570,576 - 57,580,788 (+)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

Ndufb3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	477,144 - 483,122 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	477,138 - 483,122 (-)	NCBI	ChiLan1.0	ChiLan1.0

NDUFB3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	103,698,768 - 103,712,575 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	103,713,797 - 103,727,575 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	88,329,424 - 88,343,180 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	206,487,855 - 206,501,709 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	206,487,905 - 206,501,709 (+)	Ensembl	panpan1.1		panPan2

NDUFB3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	10,240,109 - 10,247,487 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	10,240,213 - 10,247,486 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	11,124,653 - 11,132,816 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	10,144,770 - 10,152,924 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	10,145,621 - 10,157,006 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	10,126,399 - 10,134,586 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	10,104,329 - 10,112,494 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	10,098,151 - 10,106,332 (+)	NCBI		UU_Cfam_GSD_1.0

NDUFB3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	104,747,678 - 104,759,139 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	104,747,835 - 104,759,137 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	116,072,351 - 116,083,636 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NDUFB3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	86,723,212 - 86,735,837 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	86,723,253 - 86,735,980 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	112,683,374 - 112,696,127 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ndufb3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624889	131,732 - 141,915 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624889	126,294 - 141,572 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005338898	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013364584	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013364586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021735654	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000009625 ⟹ ENSSTOP00000008634

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936726	338,423 - 349,943 (+)	Ensembl

RefSeq Acc Id:

XM_005338898 ⟹ XP_005338955

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	158,368,034 - 158,379,651 (+)	NCBI
SpeTri2.0	NW_004936726	338,384 - 349,943 (+)	NCBI

Sequence:

show sequence

TCCTACTGTAAGGAACTGTACTTGACAACTTCCGTTTCCGGTTGGCTCCGGCTGGACGGTTGAC
TATTGAGTGTCCTGAGAGGTCAAATTGCTGTAAGACATGGCTCCTGGACATGGACATGGACATG
AACATGGTCATGGAAAACTAGAACTTCCAGATTATAGGCATTGGAAGATAGAAGGGACACCATT
ACAAACTGTCCAGGAGAAGCTGGCTGCAAAAGGGCTCAGGGATCCATGGGGCCGGAATGAAGCT
TGGAGATACATGGGTGGCTTTGCACACAATGTTTCCTTTGTTGGTGTATTATTAAAAGGATTTA
AATGGGGATTTGCTGCTTTTGTGGTAGCCGTAGGGGCCGAATATTATCTGGAGTCCCAGAAAAA
AGATAACAATCATCACTGAAGATAGTATCTGGAAATATCTTAGTAACTCCTTTATTCTCTTATA
AAAATAAGATTTCTTCACTATATCATACTTGTCCATGTGTTTGCCCCTTAAAGAATATTAGTAA
GGATTAATAAAGTAAGAAAAACATA

hide sequence

RefSeq Acc Id:

XM_013364584 ⟹ XP_013220038

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	158,368,040 - 158,379,651 (+)	NCBI
SpeTri2.0	NW_004936726	338,397 - 349,943 (+)	NCBI

Sequence:

show sequence

AACTGTACTTGACAACTTCCGTTTCCGGTTGGCTCCGGCTGGACGGTTGACTATTGAGTGTCCT
GAGAGGTCAAATTGCTGTAAGAAAAAGTTCATGTGATCATACGTATTCAAAATCATTAAGACAA
CATTCTAAAAGAATCATCTAAATAAAGACATGGCTCCTGGACATGGACATGGACATGAACATGG
TCATGGAAAACTAGAACTTCCAGATTATAGGCATTGGAAGATAGAAGGGACACCATTACAAACT
GTCCAGGAGAAGCTGGCTGCAAAAGGGCTCAGGGATCCATGGGGCCGGAATGAAGCTTGGAGAT
ACATGGGTGGCTTTGCACACAATGTTTCCTTTGTTGGTGTATTATTAAAAGGATTTAAATGGGG
ATTTGCTGCTTTTGTGGTAGCCGTAGGGGCCGAATATTATCTGGAGTCCCAGAAAAAAGATAAC
AATCATCACTGAAGATAGTATCTGGAAATATCTTAGTAACTCCTTTATTCTCTTATAAAAATAA
GATTTCTTCACTATATCATACTTGTCCATGTGTTTGCCCCTTAAAGAATATTAGTAAGGATTAA
TAAAGTAAGAAAAACATA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005338955	(Get FASTA)	NCBI Sequence Viewer
	XP_013220038	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000008634.2
GenBank Protein	KAG3274973	(Get FASTA)	NCBI Sequence Viewer
	KAG3274974	(Get FASTA)	NCBI Sequence Viewer
	KAG3274975	(Get FASTA)	NCBI Sequence Viewer
	KAG3274976	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005338955 ⟸ XM_005338898
- UniProtKB:	I3MDW8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAPGHGHGHEHGHGKLELPDYRHWKIEGTPLQTVQEKLAAKGLRDPWGRNEAWRYMGGFAHNVS FVGVLLKGFKWGFAAFVVAVGAEYYLESQKKDNNHH hide sequence

RefSeq Acc Id:	XP_013220038 ⟸ XM_013364584
- UniProtKB:	I3MDW8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAPGHGHGHEHGHGKLELPDYRHWKIEGTPLQTVQEKLAAKGLRDPWGRNEAWRYMGGFAHNVS FVGVLLKGFKWGFAAFVVAVGAEYYLESQKKDNNHH hide sequence

RefSeq Acc Id:

ENSSTOP00000008634 ⟸ ENSSTOT00000009625

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000009635	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000009625.3	UniProtKB/TrEMBL
InterPro	NDUFB3	UniProtKB/TrEMBL
NCBI Gene	Ndufb3	ENTREZGENE
PANTHER	NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3	UniProtKB/TrEMBL
	PTHR15082	UniProtKB/TrEMBL
Pfam	NDUF_B12	UniProtKB/TrEMBL
UniProt	I3MDW8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM