RBMX2 (RNA binding motif protein X-linked 2) - Rat Genome Database

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Gene: RBMX2 (RNA binding motif protein X-linked 2) Canis lupus familiaris
Analyze
Symbol: RBMX2
Name: RNA binding motif protein X-linked 2
RGD ID: 12434550
Description: ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN mRNA splicing, via spliceosome (inferred); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); syndromic X-linked intellectual disability Lubs type (ortholog); FOUND IN catalytic step 2 spliceosome (inferred); endoplasmic reticulum (inferred); nuclear membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RNA binding motif protein, X-linked 2; RNA-binding motif protein, X-linked 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X101,533,732 - 101,547,147 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX101,533,835 - 101,544,552 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX87,711,320 - 87,724,740 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X103,393,045 - 103,406,509 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX103,393,156 - 103,406,483 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X100,807,764 - 100,821,183 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X102,653,440 - 102,666,817 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X102,431,938 - 102,445,358 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RBMX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X101,533,732 - 101,547,147 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX101,533,835 - 101,544,552 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX87,711,320 - 87,724,740 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X103,393,045 - 103,406,509 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX103,393,156 - 103,406,483 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X100,807,764 - 100,821,183 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X102,653,440 - 102,666,817 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X102,431,938 - 102,445,358 (+)NCBIUU_Cfam_GSD_1.0
RBMX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X130,401,987 - 130,413,656 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX130,401,987 - 130,413,656 (+)EnsemblGRCh38hg38GRCh38
GRCh37X129,535,961 - 129,547,630 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X129,363,624 - 129,374,998 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X129,261,758 - 129,273,163NCBI
CeleraX129,922,409 - 129,933,783 (+)NCBICelera
Cytogenetic MapXq26.1NCBI
HuRefX118,931,323 - 118,942,334 (+)NCBIHuRef
CHM1_1X129,447,576 - 129,458,950 (+)NCBICHM1_1
T2T-CHM13v2.0X128,721,817 - 128,733,484 (+)NCBIT2T-CHM13v2.0
Rbmx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X47,783,881 - 47,799,596 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX47,783,881 - 47,799,600 (+)EnsemblGRCm39 Ensembl
GRCm38X48,695,004 - 48,710,719 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX48,695,004 - 48,710,723 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X46,048,181 - 46,063,896 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X44,939,631 - 44,955,346 (+)NCBIMGSCv36mm8
CeleraX36,198,827 - 36,211,268 (+)NCBICelera
Cytogenetic MapXA5NCBI
cM MapX25.69NCBI
Rbmx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X132,766,395 - 132,774,120 (+)NCBIGRCr8
mRatBN7.2X127,888,514 - 127,896,239 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX127,888,438 - 127,896,869 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX130,014,285 - 130,022,027 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X133,585,048 - 133,592,773 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X131,111,456 - 131,119,198 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X135,550,931 - 135,558,440 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX135,550,834 - 135,558,440 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X135,621,255 - 135,628,591 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X135,113,789 - 135,121,414 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX126,836,235 - 126,843,698 (+)NCBICelera
Cytogenetic MapXq36NCBI
Rbmx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554734,654,748 - 4,664,590 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554734,654,257 - 4,664,419 (-)NCBIChiLan1.0ChiLan1.0
RBMX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X129,822,590 - 129,833,670 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X129,826,204 - 129,837,284 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X119,528,923 - 119,540,319 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X129,820,864 - 129,831,902 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX129,820,864 - 129,831,902 (+)Ensemblpanpan1.1panPan2
Rbmx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X99,741,791 - 99,754,645 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364791,233,899 - 1,245,619 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364791,232,921 - 1,245,665 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBMX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX106,880,912 - 106,890,390 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X106,880,912 - 106,890,391 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RBMX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X105,660,294 - 105,671,417 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX105,660,614 - 105,670,921 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606543,080,371 - 43,091,846 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbmx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247979,679,171 - 9,690,066 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247979,679,066 - 9,689,943 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RBMX2
58 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 2 13 4 6 9 9 1
Low 3 5 9 6 2 6 6 3 8 1 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000029787   ⟹   ENSCAFP00000027683
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX101,533,835 - 101,544,552 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845055199   ⟹   ENSCAFP00845043414
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX103,393,156 - 103,406,483 (+)Ensembl
RefSeq Acc Id: XM_005641806   ⟹   XP_005641863
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X101,533,732 - 101,547,147 (+)NCBI
Dog10K_Boxer_TashaX87,711,320 - 87,724,740 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038450853   ⟹   XP_038306781
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X103,393,045 - 103,406,509 (+)NCBI
RefSeq Acc Id: XM_038524322   ⟹   XP_038380250
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X100,807,764 - 100,821,183 (+)NCBI
RefSeq Acc Id: XM_038588294   ⟹   XP_038444222
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X102,431,938 - 102,445,358 (+)NCBI
RefSeq Acc Id: XM_038652814   ⟹   XP_038508742
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X102,653,440 - 102,666,817 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005641863   ⟸   XM_005641806
- UniProtKB: A0A8C0N281 (UniProtKB/TrEMBL),   A0A8I3QBH7 (UniProtKB/TrEMBL),   A0A8C0JHZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000027683   ⟸   ENSCAFT00000029787
RefSeq Acc Id: XP_038380250   ⟸   XM_038524322
RefSeq Acc Id: XP_038508742   ⟸   XM_038652814
RefSeq Acc Id: XP_038306781   ⟸   XM_038450853
- UniProtKB: A0A8C0N281 (UniProtKB/TrEMBL),   A0A8I3QBH7 (UniProtKB/TrEMBL),   A0A8C0JHZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038444222   ⟸   XM_038588294
- UniProtKB: A0A8C0JHZ5 (UniProtKB/TrEMBL),   A0A8C0N281 (UniProtKB/TrEMBL),   A0A8I3QBH7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845043414   ⟸   ENSCAFT00845055199
Protein Domains
RRM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018770 Ensembl
  ENSCAFG00000053540 UniProtKB/TrEMBL
  ENSCAFG00030011824 UniProtKB/TrEMBL
  ENSCAFG00040022047 UniProtKB/TrEMBL
  ENSCAFG00845031049 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000094018.1 UniProtKB/TrEMBL
  ENSCAFT00030021891.1 UniProtKB/TrEMBL
  ENSCAFT00040040922.1 UniProtKB/TrEMBL
  ENSCAFT00845055199 ENTREZGENE
  ENSCAFT00845055199.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  RRM_Ist3_like UniProtKB/TrEMBL
KEGG Report cfa:492135 UniProtKB/TrEMBL
NCBI Gene RBMX2 ENTREZGENE
PANTHER RNA-BINDING MOTIF PROTEIN, X-LINKED 2 UniProtKB/TrEMBL
  RNA-BINDING MOTIF PROTEIN, X-LINKED 2 UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8C0JHZ5 ENTREZGENE
  A0A8C0N281 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QBH7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:54669 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-01 RBMX2  RNA binding motif protein X-linked 2    RNA binding motif protein, X-linked 2  Symbol and/or name change 5135510 APPROVED