SMIM12 (small integral membrane protein 12)

Gene: SMIM12 (small integral membrane protein 12) Canis lupus familiaris

Analyze

Symbol:

SMIM12

Name:

small integral membrane protein 12

RGD ID:

12428205

Description:

ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

C15H1orf212

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	7,121,532 - 7,126,450 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	7,121,189 - 7,126,450 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	7,360,099 - 7,364,782 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	7,266,656 - 7,271,543 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	7,270,619 - 7,271,543 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	7,129,342 - 7,134,017 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	7,177,167 - 7,182,038 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	7,191,291 - 7,196,173 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease dominant intermediate C (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:16341006

Genomics

Comparative Map Data

SMIM12
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	7,121,532 - 7,126,450 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	7,121,189 - 7,126,450 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	7,360,099 - 7,364,782 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	7,266,656 - 7,271,543 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	7,270,619 - 7,271,543 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	7,129,342 - 7,134,017 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	7,177,167 - 7,182,038 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	7,191,291 - 7,196,173 (+)	NCBI		UU_Cfam_GSD_1.0

SMIM12
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	34,850,362 - 34,859,749 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	34,712,737 - 34,859,755 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	35,315,963 - 35,325,350 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	35,091,711 - 35,097,934 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	33,589,547 - 33,599,002 (-)	NCBI		Celera
Cytogenetic Map	1	p34.3	NCBI
HuRef	1	33,433,527 - 33,442,967 (-)	NCBI		HuRef
CHM1_1	1	35,431,467 - 35,440,901 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	34,712,985 - 34,722,442 (-)	NCBI		T2T-CHM13v2.0

Smim12
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	127,137,577 - 127,141,602 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	127,137,577 - 127,141,602 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	127,243,784 - 127,247,809 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	127,243,784 - 127,247,809 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	126,921,028 - 126,925,053 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	126,746,145 - 126,750,113 (+)	NCBI		MGSCv36	mm8
Celera	4	125,578,251 - 125,582,269 (+)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI
cM Map	4	61.41	NCBI

Smim12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	144,853,887 - 144,857,746 (+)	NCBI		GRCr8
mRatBN7.2	5	139,569,367 - 139,573,276 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	139,569,391 - 139,574,320 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	142,264,872 - 142,268,683 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	144,034,870 - 144,038,681 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	144,035,643 - 144,039,454 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	145,311,317 - 145,315,185 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	145,311,375 - 145,315,185 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	149,080,643 - 149,084,601 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	146,692,300 - 146,696,110 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	138,063,425 - 138,067,235 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Smim12
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	12,972,797 - 12,976,962 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	12,972,797 - 12,976,963 (-)	NCBI	ChiLan1.0	ChiLan1.0

SMIM12
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	191,986,403 - 191,991,175 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	191,107,515 - 191,113,869 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	34,121,669 - 34,126,465 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1 Ensembl	1	35,303,890 - 35,304,168 (-)	Ensembl	panpan1.1		panPan2

Smim12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	51,662,093 - 51,667,022 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	17,486,894 - 17,487,982 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	17,486,883 - 17,491,222 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SMIM12
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	91,109,698 - 91,109,976 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	91,109,044 - 91,113,686 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SMIM12
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	98,028,144 - 98,032,620 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	98,028,144 - 98,032,290 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666256	42,915 - 47,683 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Smim12
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	17,894,153 - 17,897,758 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	17,894,154 - 17,897,796 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SMIM12
75 total Variants

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001313885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005628969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005628970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022427649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038687148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038687149	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038687150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038687151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000372	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000085864 ⟹ ENSCAFP00000049095

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	15	7,121,189 - 7,126,450 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845027453 ⟹ ENSCAFP00845021599

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	15	7,270,619 - 7,271,543 (+)	Ensembl

RefSeq Acc Id:

NM_001313885 ⟹ NP_001300814

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	15	7,121,532 - 7,126,450 (+)	NCBI
Dog10K_Boxer_Tasha	15	7,360,099 - 7,364,782 (+)	NCBI
ROS_Cfam_1.0	15	7,266,656 - 7,271,543 (+)	NCBI
UMICH_Zoey_3.1	15	7,129,342 - 7,134,017 (+)	NCBI
UNSW_CanFamBas_1.0	15	7,177,167 - 7,182,038 (+)	NCBI
UU_Cfam_GSD_1.0	15	7,191,291 - 7,196,173 (+)	NCBI

Sequence:

show sequence

GGCGGCGGCCGGACCGGGAGCGCGGCTGCGGCTGCGGCTGCGGCGCGGATGTCATGTGGCCTGT
GCTTTGGACCGTGGTGCGTACCTATGCTCCCTATGTCACGTTTCCTGTGGCCTTTGTGGTCGGG
GCTGTGGGTTACCACTTGGAATGGTTCATCCGGGGAAAGGATCCCCAGCCTGCGGAGGAGGAGA
AGAGCATCTCTGAGCGCCGGGAGGACCGCAAGCTGGATGAACTGCTAGGCAAGGACCACACCCA
GGTGGTGAGCCTTAAGGACAAGCTGGAATTTGCCCCTAAAGCCGTCCTGAACAGAAACCGCCCG
GAAAAGAATTAACGAAAGACACAGAGCCCTGTGGGCCCTTGTGGGCCACCACCGGCCCTGCCAC
CATGTCTGCGCCGCTCCAGAACCCACATCTGATTTGCTTTATGGCTTATTCTGGCCCCTCGCGT
ACCACCCGGCCAGGCAGACGTGTGAGCAGCGGAGGGGCCGGTGAAGAGGAAGGCCCTTGAGGGT
GCTGCTGGCCTGAAGGCTCATCTGTCAGGCTTCTGCTCGTCGGGCGCACGGCTGGGAGGACTGT
CATGAAATGAATGACGGCTGTCTGTTTCTTTGGGGAGGCCCCCCTGGCCTCACGTGGGAGCGGC
TGGGGTTGGGGTGCTGCCTTAGGAGGTACACCTGCGTGCCCAGTTCCAGTGCACACTGGGAAGA
ATGCAACCAGCTGCCTGCCTCCCGTTGCTGGCTTGCCCACCCCCCTCTCACGCTTCCTGAAATC
CTGTCAGCTCAGGAGTGAGACTCCCTGGGGAGGAAAGCCTTTTACTGTTCTTGGAAGCCCAGGC
TGCGTACCTTGGGGCAGGGGGATATGCTTGAAAACAGTCTCATTCTTCGCACACACCCACCCCC
CCATCACTGTATGGTACAAAACCTGATTAAAGTGGCATCTGAGAACTGTC

hide sequence

RefSeq Acc Id:

XM_038687148 ⟹ XP_038543076

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	15	7,268,726 - 7,271,543 (+)	NCBI

RefSeq Acc Id:

XM_038687149 ⟹ XP_038543077

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	15	7,266,705 - 7,271,543 (+)	NCBI

RefSeq Acc Id:

XM_038687150 ⟹ XP_038543078

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	15	7,269,907 - 7,271,543 (+)	NCBI

RefSeq Acc Id:

XM_038687151 ⟹ XP_038543079

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	15	7,268,563 - 7,271,543 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001300814	(Get FASTA)	NCBI Sequence Viewer
	XP_038543076	(Get FASTA)	NCBI Sequence Viewer
	XP_038543077	(Get FASTA)	NCBI Sequence Viewer
	XP_038543078	(Get FASTA)	NCBI Sequence Viewer
	XP_038543079	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	E2R5I0	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000049095.2
	ENSCAFP00040013976.1
	ENSCAFP00805020758
	ENSCAFP00845021599
	ENSCAFP00845021599.1

RefSeq Acc Id:	NP_001300814 ⟸ NM_001313885
- UniProtKB:	E2R5I0 (UniProtKB/Swiss-Prot), A0A8C0QYR1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MWPVLWTVVRTYAPYVTFPVAFVVGAVGYHLEWFIRGKDPQPAEEEKSISERREDRKLDELLGK DHTQVVSLKDKLEFAPKAVLNRNRPEKN hide sequence

RefSeq Acc Id:

ENSCAFP00000049095 ⟸ ENSCAFT00000085864

RefSeq Acc Id:	XP_038543077 ⟸ XM_038687149
- Peptide Label:	isoform X2
- UniProtKB:	E2R5I0 (UniProtKB/Swiss-Prot), A0A8C0QYR1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038543079 ⟸ XM_038687151
- Peptide Label:	isoform X2
- UniProtKB:	E2R5I0 (UniProtKB/Swiss-Prot), A0A8C0QYR1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038543076 ⟸ XM_038687148
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038543078 ⟸ XM_038687150
- Peptide Label:	isoform X2
- UniProtKB:	E2R5I0 (UniProtKB/Swiss-Prot), A0A8C0QYR1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845021599 ⟸ ENSCAFT00845027453

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000046486	Ensembl, UniProtKB/Swiss-Prot
	ENSCAFG00040008661	UniProtKB/Swiss-Prot
	ENSCAFG00805014575	UniProtKB/Swiss-Prot
	ENSCAFG00845015395	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSCAFT00000085864.2	UniProtKB/Swiss-Prot
	ENSCAFT00040016138.1	UniProtKB/Swiss-Prot
	ENSCAFT00805026457	UniProtKB/Swiss-Prot
	ENSCAFT00845027453	ENTREZGENE
	ENSCAFT00845027453.1	UniProtKB/Swiss-Prot
InterPro	UPF0767	UniProtKB/Swiss-Prot
KEGG Report	cfa:100682960	UniProtKB/Swiss-Prot
NCBI Gene	SMIM12	ENTREZGENE
PANTHER	PTHR28599	UniProtKB/Swiss-Prot
	SMALL INTEGRAL MEMBRANE PROTEIN 12	UniProtKB/Swiss-Prot
Pfam	UPF0767	UniProtKB/Swiss-Prot
UniProt	A0A8C0QYR1	ENTREZGENE
	E2R5I0	ENTREZGENE, UniProtKB/Swiss-Prot
VGNC ID	VGNC:54268	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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