UQCC3 (ubiquinol-cytochrome c reductase complex assembly factor 3) - Rat Genome Database

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Gene: UQCC3 (ubiquinol-cytochrome c reductase complex assembly factor 3) Canis lupus familiaris
Analyze
Symbol: UQCC3
Name: ubiquinol-cytochrome c reductase complex assembly factor 3
RGD ID: 12399337
Description: ENCODES a protein that exhibits cardiolipin binding (inferred); phosphatidic acid binding (inferred); INVOLVED IN cristae formation (inferred); mitochondrial electron transport, ubiquinol to cytochrome c (inferred); mitochondrial respiratory chain complex III assembly (inferred); ASSOCIATED WITH intellectual disability (ortholog); Larsen-like syndrome B3GAT3 type (ortholog); leukocyte adhesion deficiency 3 (ortholog); FOUND IN mitochondrial respiratory chain complex III (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C18H11orf83; ubiquinol-cytochrome-c reductase complex assembly factor 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,984,203 - 53,985,496 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,984,771 - 53,985,422 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,589,252 - 52,590,539 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01855,036,321 - 55,037,608 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1855,036,884 - 55,037,536 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,132,577 - 54,133,863 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,707,591 - 53,708,879 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,503,348 - 54,504,636 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UQCC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,984,203 - 53,985,496 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,984,771 - 53,985,422 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,589,252 - 52,590,539 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01855,036,321 - 55,037,608 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1855,036,884 - 55,037,536 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,132,577 - 54,133,863 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,707,591 - 53,708,879 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,503,348 - 54,504,636 (-)NCBIUU_Cfam_GSD_1.0
UQCC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,671,673 - 62,673,686 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,670,273 - 62,673,686 (+)EnsemblGRCh38hg38GRCh38
GRCh371162,439,145 - 62,441,158 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,195,702 - 62,196,428 (+)NCBINCBI36Build 36hg18NCBI36
Celera1159,768,705 - 59,769,431 (+)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,767,992 - 58,770,027 (+)NCBIHuRef
CHM1_11162,322,237 - 62,324,273 (+)NCBICHM1_1
T2T-CHM13v2.01162,661,091 - 62,663,101 (+)NCBIT2T-CHM13v2.0
Uqcc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,857,378 - 8,858,297 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,857,378 - 8,858,287 (-)EnsemblGRCm39 Ensembl
GRCm38198,880,014 - 8,880,933 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,880,014 - 8,880,923 (-)EnsemblGRCm38mm10GRCm38
MGSCv37198,954,504 - 8,955,423 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36198,947,059 - 8,947,978 (-)NCBIMGSCv36mm8
Celera198,640,616 - 8,641,535 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.9NCBI
Uqcc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,202,700 - 215,203,478 (-)NCBIGRCr8
mRatBN7.21205,773,591 - 205,774,369 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,772,780 - 205,774,376 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,182,040 - 214,182,818 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,216,967 - 221,217,745 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,909,817 - 213,910,595 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01225,076,301 - 225,077,079 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,076,301 - 225,077,079 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,013,921 - 232,014,699 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,549,821 - 211,550,599 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1203,286,367 - 203,287,145 (-)NCBICelera
Cytogenetic Map1q43NCBI
LOC102013363
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599526,609 - 541,643 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955599540,598 - 541,643 (-)NCBIChiLan1.0ChiLan1.0
LOC134731237
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2963,898,019 - 63,898,891 (+)NCBINHGRI_mPanPan1-v2
LOC101965457
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,475,349 - 10,477,440 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581590,503 - 591,612 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581590,503 - 591,225 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UQCC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,074,784 - 9,078,541 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.129,077,055 - 9,078,649 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,423,620 - 8,424,391 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103233987
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,234,810 - 11,235,569 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,235,023 - 11,235,492 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,568,744 - 108,570,182 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101724106
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,177,499 - 1,178,168 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,177,498 - 1,178,171 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in UQCC3
30 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 5 12 2 10 6
Low 1 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000024893   ⟹   ENSCAFP00000023096
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1853,984,771 - 53,985,422 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845015361   ⟹   ENSCAFP00845011928
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1855,036,884 - 55,037,536 (-)Ensembl
RefSeq Acc Id: XM_038425313   ⟹   XP_038281241
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01855,036,321 - 55,037,608 (-)NCBI
RefSeq Acc Id: XM_038501582   ⟹   XP_038357510
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11854,132,577 - 54,133,863 (-)NCBI
RefSeq Acc Id: XM_038564268   ⟹   XP_038420196
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01854,503,348 - 54,504,636 (-)NCBI
RefSeq Acc Id: XM_038628408   ⟹   XP_038484336
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01853,707,591 - 53,708,879 (-)NCBI
RefSeq Acc Id: XM_849946   ⟹   XP_855039
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11853,984,203 - 53,985,496 (-)NCBI
Dog10K_Boxer_Tasha1852,589,252 - 52,590,539 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_855039   ⟸   XM_849946
- UniProtKB: A0A8C0MI20 (UniProtKB/TrEMBL),   A0A8C0KIT9 (UniProtKB/TrEMBL),   A0A8I3N4J6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000023096   ⟸   ENSCAFT00000024893
RefSeq Acc Id: XP_038357510   ⟸   XM_038501582
RefSeq Acc Id: XP_038484336   ⟸   XM_038628408
RefSeq Acc Id: XP_038281241   ⟸   XM_038425313
- UniProtKB: A0A8C0MI20 (UniProtKB/TrEMBL),   A0A8C0KIT9 (UniProtKB/TrEMBL),   A0A8I3N4J6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038420196   ⟸   XM_038564268
- UniProtKB: A0A8C0KIT9 (UniProtKB/TrEMBL),   A0A8C0MI20 (UniProtKB/TrEMBL),   A0A8I3N4J6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845011928   ⟸   ENSCAFT00845015361

Promoters
RGD ID:13686650
Promoter ID:EPDNEW_C4718
Type:initiation region
Name:UQCC3_1
Description:ubiquinol-cytochrome c reductase complex assembly factor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11853,985,467 - 53,985,527EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015715 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006054 UniProtKB/TrEMBL
  ENSCAFG00040019249 UniProtKB/TrEMBL
  ENSCAFG00845008750 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000024893.5 UniProtKB/TrEMBL
  ENSCAFT00030011092.1 UniProtKB/TrEMBL
  ENSCAFT00040035587.1 UniProtKB/TrEMBL
  ENSCAFT00845015361 ENTREZGENE
  ENSCAFT00845015361.1 UniProtKB/TrEMBL
InterPro UQCC3 UniProtKB/TrEMBL
KEGG Report cfa:612210 UniProtKB/TrEMBL
NCBI Gene UQCC3 ENTREZGENE
PANTHER PTHR36465 UniProtKB/TrEMBL
  UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 UniProtKB/TrEMBL
Pfam UQCC3 UniProtKB/TrEMBL
UniProt A0A8C0KIT9 ENTREZGENE
  A0A8C0MI20 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N4J6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:48161 ENTREZGENE