NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10) - Rat Genome Database

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Gene: NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10) Canis lupus familiaris
Analyze
Symbol: NDUFA10
Name: NADH:ubiquinone oxidoreductase subunit A10
RGD ID: 12385137
Description: ENCODES a protein that exhibits deoxynucleoside kinase activity (inferred); NADH dehydrogenase (ubiquinone) activity (inferred); INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (ortholog); mitochondrial respiratory chain complex I assembly (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Bethlem Myopathy 1A (ortholog); chromosome 2q37 deletion syndrome (ortholog); D-2-hydroxyglutaric aciduria 1 (ortholog); FOUND IN mitochondrial respiratory chain complex I (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CI-42kD; Complex I-42kD; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial-like; NADH-ubiquinone oxidoreductase 42 kDa subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12549,920,748 - 49,968,966 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2549,920,894 - 49,968,901 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2550,417,870 - 50,466,092 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02550,312,005 - 50,360,202 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2550,312,005 - 50,360,188 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12550,183,360 - 50,231,504 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02549,974,238 - 50,022,369 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02550,205,078 - 50,253,281 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NDUFA10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12549,920,748 - 49,968,966 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2549,920,894 - 49,968,901 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2550,417,870 - 50,466,092 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02550,312,005 - 50,360,202 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2550,312,005 - 50,360,188 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12550,183,360 - 50,231,504 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02549,974,238 - 50,022,369 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02550,205,078 - 50,253,281 (-)NCBIUU_Cfam_GSD_1.0
NDUFA10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382239,892,442 - 240,025,342 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2239,892,450 - 240,025,743 (-)EnsemblGRCh38hg38GRCh38
GRCh372240,831,859 - 240,964,759 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,548,829 - 240,613,471 (-)NCBINCBI36Build 36hg18NCBI36
Build 342240,620,147 - 240,684,788NCBI
Celera2234,570,056 - 234,638,352 (-)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2232,654,836 - 232,722,773 (-)NCBIHuRef
CHM1_12240,902,845 - 240,970,868 (-)NCBICHM1_1
T2T-CHM13v2.02240,386,242 - 240,518,068 (-)NCBIT2T-CHM13v2.0
Ndufa10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39192,367,208 - 92,401,547 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl192,366,732 - 92,401,582 (-)EnsemblGRCm39 Ensembl
GRCm38192,439,486 - 92,473,825 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl192,439,010 - 92,473,860 (-)EnsemblGRCm38mm10GRCm38
MGSCv37194,336,285 - 94,370,335 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,270,114 - 94,304,164 (-)NCBIMGSCv36mm8
Celera195,379,073 - 95,413,122 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map146.4NCBI
Ndufa10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89100,454,498 - 100,490,023 (-)NCBIGRCr8
mRatBN7.2993,007,034 - 93,041,825 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl993,007,042 - 93,042,560 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9101,441,793 - 101,476,601 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09106,577,557 - 106,612,365 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09104,934,713 - 104,969,479 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0999,617,051 - 99,651,827 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl999,617,052 - 99,651,813 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0999,282,165 - 99,316,943 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4991,655,135 - 91,689,653 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1991,859,903 - 91,894,383 (-)NCBI
Celera990,544,387 - 90,579,150 (-)NCBICelera
Cytogenetic Map9q36NCBI
Ndufa10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555421,329,212 - 1,370,695 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555421,329,802 - 1,370,109 (+)NCBIChiLan1.0ChiLan1.0
NDUFA10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213142,609,806 - 142,678,378 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B142,624,772 - 142,689,688 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B127,204,900 - 127,269,478 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B246,022,168 - 246,085,828 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B246,022,168 - 246,087,658 (-)Ensemblpanpan1.1panPan2
Ndufa10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303191,747,635 - 191,783,140 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367451,436,234 - 1,471,843 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367451,436,257 - 1,471,785 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFA10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15138,986,421 - 139,031,897 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115138,999,174 - 139,031,892 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215153,792,416 - 153,825,373 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFA10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110126,018,383 - 126,082,847 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10126,015,852 - 126,083,082 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604073,324,402 - 73,390,721 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndufa10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248474,370,570 - 4,412,393 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248474,371,264 - 4,412,334 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NDUFA10
882 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000020004   ⟹   ENSCAFP00000018556
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2549,920,894 - 49,968,901 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845053825   ⟹   ENSCAFP00845042304
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2550,312,005 - 50,360,188 (-)Ensembl
RefSeq Acc Id: XM_022409746   ⟹   XP_022265454
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12549,920,748 - 49,968,966 (-)NCBI
Dog10K_Boxer_Tasha2550,417,870 - 50,466,092 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038435965   ⟹   XP_038291893
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02550,312,005 - 50,360,202 (-)NCBI
RefSeq Acc Id: XM_038435966   ⟹   XP_038291894
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02550,312,005 - 50,360,202 (-)NCBI
RefSeq Acc Id: XM_038510887   ⟹   XP_038366815
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12550,183,360 - 50,231,504 (-)NCBI
RefSeq Acc Id: XM_038510888   ⟹   XP_038366816
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12550,183,360 - 50,231,504 (-)NCBI
RefSeq Acc Id: XM_038574385   ⟹   XP_038430313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02550,205,078 - 50,253,281 (-)NCBI
RefSeq Acc Id: XM_038574386   ⟹   XP_038430314
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02550,205,078 - 50,253,281 (-)NCBI
RefSeq Acc Id: XM_038638620   ⟹   XP_038494548
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02549,974,238 - 50,022,369 (-)NCBI
RefSeq Acc Id: XM_038638621   ⟹   XP_038494549
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02549,974,238 - 50,022,369 (-)NCBI
RefSeq Acc Id: XM_845210   ⟹   XP_850303
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12549,920,748 - 49,968,966 (-)NCBI
Dog10K_Boxer_Tasha2550,417,870 - 50,466,092 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_850303   ⟸   XM_845210
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LJY8 (UniProtKB/TrEMBL),   A0A8C0TG47 (UniProtKB/TrEMBL),   A0A8I3Q997 (UniProtKB/TrEMBL),   A0A8P0PGG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022265454   ⟸   XM_022409746
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TIE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000018556   ⟸   ENSCAFT00000020004
RefSeq Acc Id: XP_038366816   ⟸   XM_038510888
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038366815   ⟸   XM_038510887
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038494549   ⟸   XM_038638621
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038494548   ⟸   XM_038638620
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038291894   ⟸   XM_038435966
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LJY8 (UniProtKB/TrEMBL),   A0A8C0TG47 (UniProtKB/TrEMBL),   A0A8I3Q997 (UniProtKB/TrEMBL),   A0A8P0PGG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038291893   ⟸   XM_038435965
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TIE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038430314   ⟸   XM_038574386
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LJY8 (UniProtKB/TrEMBL),   A0A8C0TG47 (UniProtKB/TrEMBL),   A0A8I3Q997 (UniProtKB/TrEMBL),   A0A8P0PGG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038430313   ⟸   XM_038574385
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TIE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845042304   ⟸   ENSCAFT00845053825
Protein Domains
Deoxynucleoside kinase

Promoters
RGD ID:13687839
Promoter ID:EPDNEW_C5908
Type:initiation region
Name:NDUFA10_1
Description:NADH:ubiquinone oxidoreductase subunit A10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12549,968,899 - 49,968,959EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012591 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040021727 UniProtKB/TrEMBL
  ENSCAFG00845030335 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020004.5 UniProtKB/TrEMBL
  ENSCAFT00000105698.1 UniProtKB/TrEMBL
  ENSCAFT00040040315.1 UniProtKB/TrEMBL
  ENSCAFT00040040357.1 UniProtKB/TrEMBL
  ENSCAFT00040040446.1 UniProtKB/TrEMBL
  ENSCAFT00845053825 ENTREZGENE
  ENSCAFT00845053825.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro DNK_dom UniProtKB/TrEMBL
  NDUFA10 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene NDUFA10 ENTREZGENE
PANTHER DEOXYNUCLEOSIDE KINASE UniProtKB/TrEMBL
  NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam dNK UniProtKB/TrEMBL
PIRSF NADH_UQ_42KD UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0LJY8 ENTREZGENE
  A0A8C0TFF2_CANLF UniProtKB/TrEMBL
  A0A8C0TG47 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TIE1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q997 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PGG2 ENTREZGENE, UniProtKB/TrEMBL
  NDUAA_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:54974 ENTREZGENE