TEKT1 (tektin 1) - Rat Genome Database

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Gene: TEKT1 (tektin 1) Canis lupus familiaris
Analyze
Symbol: TEKT1
Name: tektin 1
RGD ID: 12379613
Description: INVOLVED IN cilium assembly (inferred); cilium movement involved in cell motility (inferred); flagellated sperm motility (inferred); ASSOCIATED WITH common variable immunodeficiency (ortholog); congenital myasthenic syndrome 2A (ortholog); developmental and epileptic encephalopathy 25 (ortholog); FOUND IN axonemal A tubule inner sheath (ortholog); axonemal microtubule (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: tektin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1530,600,983 - 30,614,679 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl530,565,639 - 30,614,673 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0530,702,285 - 30,716,037 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl530,702,697 - 30,716,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1530,668,771 - 30,682,373 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0530,627,225 - 30,640,929 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0530,800,692 - 30,814,062 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:11039601   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TEKT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1530,600,983 - 30,614,679 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl530,565,639 - 30,614,673 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0530,702,285 - 30,716,037 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl530,702,697 - 30,716,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1530,668,771 - 30,682,373 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0530,627,225 - 30,640,929 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0530,800,692 - 30,814,062 (+)NCBIUU_Cfam_GSD_1.0
TEKT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38176,797,993 - 6,831,729 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl176,789,133 - 6,831,761 (-)EnsemblGRCh38hg38GRCh38
GRCh37176,701,312 - 6,735,048 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36176,644,024 - 6,675,784 (-)NCBINCBI36Build 36hg18NCBI36
Build 34176,644,024 - 6,675,784NCBI
Celera176,729,093 - 6,760,865 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef176,598,870 - 6,630,626 (-)NCBIHuRef
CHM1_1176,713,517 - 6,745,273 (-)NCBICHM1_1
T2T-CHM13v2.0176,698,681 - 6,732,423 (-)NCBIT2T-CHM13v2.0
Tekt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391172,235,543 - 72,253,268 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1172,235,548 - 72,253,268 (-)EnsemblGRCm39 Ensembl
GRCm381172,344,717 - 72,362,442 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,344,722 - 72,362,442 (-)EnsemblGRCm38mm10GRCm38
MGSCv371172,158,222 - 72,175,382 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361172,160,917 - 72,178,068 (-)NCBIMGSCv36mm8
Celera1179,864,978 - 79,882,394 (-)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1144.03NCBI
Tekt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81057,450,712 - 57,479,121 (-)NCBIGRCr8
mRatBN7.21056,952,164 - 56,980,572 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1056,952,167 - 56,980,572 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1061,615,143 - 61,643,556 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01061,103,620 - 61,132,042 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01056,602,709 - 56,631,121 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01058,895,689 - 58,924,098 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1058,895,674 - 58,924,137 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01058,636,233 - 58,663,145 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41059,219,929 - 59,248,976 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11059,233,552 - 59,262,599 (-)NCBI
Celera1056,081,049 - 56,108,364 (-)NCBICelera
Cytogenetic Map10q24NCBI
Tekt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546712,276,702 - 12,301,630 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546712,278,515 - 12,301,736 (-)NCBIChiLan1.0ChiLan1.0
TEKT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21914,387,356 - 14,427,539 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11716,353,555 - 16,393,737 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0176,830,517 - 6,862,596 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1176,819,230 - 6,851,014 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl176,819,230 - 6,851,014 (-)Ensemblpanpan1.1panPan2
Tekt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560254,683,936 - 54,697,449 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366771,195,280 - 1,216,960 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366771,195,283 - 1,216,993 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TEKT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1250,526,193 - 50,580,552 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11250,526,188 - 50,552,083 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21252,524,664 - 52,548,893 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TEKT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,161,826 - 6,184,735 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,159,008 - 6,184,711 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605915,254,603 - 15,277,787 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tekt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247867,218,590 - 7,249,538 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247867,218,533 - 7,248,593 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TEKT1
220 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 6 1 6 6 12 1
Low 5 2 14 6 5 6 8 10 5
Below cutoff 2

Sequence


RefSeq Acc Id: ENSCAFT00845003523   ⟹   ENSCAFP00845002797
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl530,702,697 - 30,716,581 (+)Ensembl
RefSeq Acc Id: NM_001003097   ⟹   NP_001003097
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1530,601,367 - 30,614,673 (+)NCBI
ROS_Cfam_1.0530,702,661 - 30,716,031 (+)NCBI
UMICH_Zoey_3.1530,668,771 - 30,682,373 (+)NCBI
UNSW_CanFamBas_1.0530,627,225 - 30,640,929 (+)NCBI
UU_Cfam_GSD_1.0530,800,692 - 30,814,062 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038664058   ⟹   XP_038519986
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0530,702,700 - 30,716,037 (+)NCBI
RefSeq Acc Id: XM_038664059   ⟹   XP_038519987
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0530,702,285 - 30,716,037 (+)NCBI
RefSeq Acc Id: XM_038664060   ⟹   XP_038519988
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0530,702,689 - 30,716,037 (+)NCBI
RefSeq Acc Id: NP_001003097   ⟸   NM_001003097
- UniProtKB: A0A8C0R1X9 (UniProtKB/TrEMBL),   A0A8C0RUM1 (UniProtKB/TrEMBL),   A0A8I3MF23 (UniProtKB/TrEMBL),   A0A8C0NRK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038519987   ⟸   XM_038664059
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NRK6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038519988   ⟸   XM_038664060
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NRK6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038519986   ⟸   XM_038664058
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NRK6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845002797   ⟸   ENSCAFT00845003523
Protein Domains
Calponin-homology (CH)

Promoters
RGD ID:13683194
Promoter ID:EPDNEW_C1263
Type:single initiation site
Name:TEKT1_1
Description:tektin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1530,601,309 - 30,601,369EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015292 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018817 UniProtKB/TrEMBL
  ENSCAFG00040000273 UniProtKB/TrEMBL
  ENSCAFG00040000330 UniProtKB/TrEMBL
  ENSCAFG00845002020 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000024286.6 UniProtKB/TrEMBL
  ENSCAFT00030034640.1 UniProtKB/TrEMBL
  ENSCAFT00030034700.1 UniProtKB/TrEMBL
  ENSCAFT00040000508.1 UniProtKB/TrEMBL
  ENSCAFT00040000557.1 UniProtKB/TrEMBL
  ENSCAFT00845003523 ENTREZGENE
  ENSCAFT00845003523.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
InterPro CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  Tektin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tektin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene TEKT1 ENTREZGENE
PANTHER CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED UniProtKB/TrEMBL
  PTHR19960 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMOOTHELIN-LIKE PROTEIN 2 UniProtKB/TrEMBL
  TEKTIN-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00307 UniProtKB/TrEMBL
  Tektin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS TEKTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PS50021 UniProtKB/TrEMBL
SMART SM00033 UniProtKB/TrEMBL
Superfamily-SCOP SSF47576 UniProtKB/TrEMBL
UniProt A0A8C0NRK6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Q1C5_CANLF UniProtKB/TrEMBL
  A0A8C0R1X9 ENTREZGENE
  A0A8C0RNH3_CANLF UniProtKB/TrEMBL
  A0A8C0RUM1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MF23 ENTREZGENE, UniProtKB/TrEMBL
  Q9TTW3 ENTREZGENE, UniProtKB/Swiss-Prot
VGNC ID VGNC:47242 ENTREZGENE