OR2A37 (olfactory receptor family 2 subfamily A member 37) - Rat Genome Database

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Gene: OR2A37 (olfactory receptor family 2 subfamily A member 37) Canis lupus familiaris
Analyze
Symbol: OR2A37
Name: olfactory receptor family 2 subfamily A member 37
RGD ID: 12379401
Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC491442; olfactory receptor 2A5-like
RGD Orthologs
Human
Mouse
Rat
Bonobo
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
NCBI Annotation Information: Annotation category: not annotated on reference assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1165,790,121 - 5,791,053 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl165,790,121 - 5,791,053 (-)EnsemblCanFam3.1canFam3CanFam3.1
UMICH_Zoey_3.1165,583,886 - 5,584,818 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0165,441,741 - 5,442,673 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0165,511,260 - 5,512,192 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
OR2A37
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1165,790,121 - 5,791,053 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl165,790,121 - 5,791,053 (-)EnsemblCanFam3.1canFam3CanFam3.1
UMICH_Zoey_3.1165,583,886 - 5,584,818 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0165,441,741 - 5,442,673 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0165,511,260 - 5,512,192 (-)NCBIUU_Cfam_GSD_1.0
OR2A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387144,109,583 - 144,110,539 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7144,109,583 - 144,110,539 (+)EnsemblGRCh38hg38GRCh38
GRCh377143,806,676 - 143,807,632 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367143,437,609 - 143,438,565 (+)NCBINCBI36Build 36hg18NCBI36
Build 347143,244,323 - 143,245,280NCBI
Celera7138,439,957 - 138,440,913 (+)NCBICelera
Cytogenetic Map7q35NCBI
HuRef7138,006,220 - 138,007,176 (+)NCBIHuRef
CHM1_17143,744,029 - 143,744,985 (+)NCBICHM1_1
T2T-CHM13v2.07145,390,058 - 145,391,014 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27143,144,903 - 143,145,859 (+)NCBI
Or2a52
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39643,143,994 - 43,144,926 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl643,140,216 - 43,146,795 (+)EnsemblGRCm39 Ensembl
GRCm38643,167,060 - 43,167,992 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl643,163,282 - 43,169,861 (+)EnsemblGRCm38mm10GRCm38
MGSCv37643,117,059 - 43,117,991 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36643,096,667 - 43,097,599 (+)NCBIMGSCv36mm8
Celera643,114,760 - 43,115,692 (+)NCBICelera
Cytogenetic Map6B2.1NCBI
cM Map621.1NCBI
Or2a52
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8472,965,128 - 72,966,057 (+)NCBIGRCr8
mRatBN7.2471,965,118 - 71,966,047 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl471,960,813 - 71,967,189 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx476,962,850 - 76,963,779 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0472,876,080 - 72,877,009 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0471,258,412 - 71,259,341 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0472,589,565 - 72,590,494 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl472,589,565 - 72,590,494 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04137,287,397 - 137,288,326 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4470,881,512 - 70,905,271 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera466,915,122 - 66,916,051 (+)NCBICelera
Cytogenetic Map4q24NCBI
LOC100976806
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26180,820,553 - 180,827,059 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1732,836,070 - 32,837,104 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07135,967,082 - 135,968,135 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17148,456,351 - 148,457,389 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7148,456,414 - 148,457,370 (+)Ensemblpanpan1.1panPan2
LOC100511653
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.19113,488,392 - 113,489,881 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29124,937,787 - 124,938,719 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103227154
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121112,841,550 - 112,844,318 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21112,842,992 - 112,843,948 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660729,615,606 - 9,616,644 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in OR2A37
9 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system nervous system reproductive system adipose tissue
High
Medium
Low
Below cutoff 1 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000024254   ⟹   ENSCAFP00000022518
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl165,790,121 - 5,791,053 (-)Ensembl
RefSeq Acc Id: NM_001388821   ⟹   NP_001375750
RefSeq Status: INFERRED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1165,583,886 - 5,584,818 (-)NCBI
UNSW_CanFamBas_1.0165,441,741 - 5,442,673 (-)NCBI
UU_Cfam_GSD_1.0165,511,260 - 5,512,192 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001375750 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00030011938.1
  ENSCAFP00040016176.1
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000022518   ⟸   ENSCAFT00000024254
RefSeq Acc Id: NP_001375750   ⟸   NM_001388821
- UniProtKB: A0A8C0YU24 (UniProtKB/TrEMBL),   A0A8C0R4T4 (UniProtKB/TrEMBL)
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000032151 Ensembl
  ENSCAFG00030007480 UniProtKB/TrEMBL
  ENSCAFG00040010076 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030013678.1 UniProtKB/TrEMBL
  ENSCAFT00040018647.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene LOC491442 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0R4T4 ENTREZGENE
  A0A8C0YU24 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:84602 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-01-14 OR2A37  olfactory receptor family 2 subfamily A member 37  LOC491442  olfactory receptor 2A5-like  Symbol and/or name change 5135510 APPROVED