DSPP (dentin sialophosphoprotein) - Rat Genome Database

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Gene: DSPP (dentin sialophosphoprotein) Canis lupus familiaris
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Symbol: DSPP
Name: dentin sialophosphoprotein
RGD ID: 12376540
Description: ENCODES a protein that exhibits collagen binding (ortholog); INVOLVED IN ameloblast differentiation (ortholog); amelogenesis (ortholog); biomineral tissue development (ortholog); ASSOCIATED WITH Autosomal Dominant Deafness 39 with Dentinogenesis Imperfecta 1 (ortholog); autosomal dominant polycystic kidney disease (ortholog); dental pulp calcification (ortholog); FOUND IN collagen-containing extracellular matrix (ortholog); extracellular matrix (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13211,017,440 - 11,022,780 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3230,932,307 - 30,937,641 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03211,069,800 - 11,075,135 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3211,069,800 - 11,075,121 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13211,152,952 - 11,158,287 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03210,978,595 - 10,983,939 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03228,970,188 - 28,976,515 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
DSPP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13211,017,440 - 11,022,780 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3230,932,307 - 30,937,641 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03211,069,800 - 11,075,135 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3211,069,800 - 11,075,121 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13211,152,952 - 11,158,287 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03210,978,595 - 10,983,939 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03228,970,188 - 28,976,515 (-)NCBIUU_Cfam_GSD_1.0
DSPP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38487,608,529 - 87,616,873 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl487,608,529 - 87,616,873 (+)EnsemblGRCh38hg38GRCh38
GRCh37488,529,681 - 88,538,025 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36488,748,705 - 88,757,049 (+)NCBINCBI36Build 36hg18NCBI36
Build 34488,886,859 - 88,895,204NCBI
Celera485,818,035 - 85,826,406 (+)NCBICelera
Cytogenetic Map4q22.1NCBI
HuRef484,275,661 - 84,283,858 (+)NCBIHuRef
CHM1_1488,506,445 - 88,514,787 (+)NCBICHM1_1
T2T-CHM13v2.0490,935,096 - 90,943,283 (+)NCBIT2T-CHM13v2.0
Dspp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395104,318,569 - 104,327,993 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5104,318,578 - 104,327,993 (+)EnsemblGRCm39 Ensembl
GRCm385104,170,703 - 104,180,127 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5104,170,712 - 104,180,127 (+)EnsemblGRCm38mm10GRCm38
MGSCv375104,599,731 - 104,609,146 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365104,411,005 - 104,420,429 (+)NCBIMGSCv36mm8
Celera5101,476,457 - 101,494,758 (+)NCBICelera
Cytogenetic Map5E5NCBI
cM Map550.59NCBI
Dspp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8145,870,232 - 5,876,339 (-)NCBIGRCr8
mRatBN7.2145,565,562 - 5,571,669 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl145,565,629 - 5,571,672 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx145,534,670 - 5,540,793 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,834,894 - 6,841,017 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0145,533,249 - 5,539,381 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0146,926,972 - 6,933,079 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl146,926,976 - 6,933,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0146,914,385 - 6,920,492 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4146,674,662 - 6,680,769 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1146,674,663 - 6,680,769 (-)NCBI
Celera145,704,631 - 5,710,738 (-)NCBICelera
Cytogenetic Map14p22NCBI
Dspp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554742,254,842 - 2,259,303 (-)NCBIChiLan1.0ChiLan1.0
DSPP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2385,617,889 - 85,623,744 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1485,880,160 - 85,886,034 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0479,903,923 - 79,909,836 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1490,630,300 - 90,635,681 (+)NCBIpanpan1.1PanPan1.1panPan2
Dspp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052852,036,925 - 2,043,572 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936905458,298 - 463,346 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936905458,062 - 463,359 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DSPP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8131,319,983 - 131,472,761 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18131,318,187 - 131,444,274 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28140,512,001 - 140,540,005 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DSPP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1735,993,669 - 35,999,443 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603714,694,483 - 14,700,534 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dspp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248724,096,001 - 4,102,392 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DSPP
78 total Variants

Expression


Sequence


RefSeq Acc Id: ENSCAFT00845027988   ⟹   ENSCAFP00845022028
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3211,069,800 - 11,075,121 (+)Ensembl
RefSeq Acc Id: XM_003434003   ⟹   XP_003434051
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13211,017,440 - 11,022,780 (+)NCBI
Dog10K_Boxer_Tasha3230,932,307 - 30,937,641 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038444079   ⟹   XP_038300007
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03211,069,800 - 11,075,135 (+)NCBI
RefSeq Acc Id: XM_038518472   ⟹   XP_038374400
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13211,152,952 - 11,158,287 (+)NCBI
RefSeq Acc Id: XM_038582184   ⟹   XP_038438112
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03228,970,188 - 28,976,515 (-)NCBI
RefSeq Acc Id: XM_038646410   ⟹   XP_038502338
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03210,978,595 - 10,983,939 (+)NCBI
RefSeq Acc Id: XP_003434051   ⟸   XM_003434003
- Sequence:
RefSeq Acc Id: XP_038374400   ⟸   XM_038518472
RefSeq Acc Id: XP_038502338   ⟸   XM_038646410
RefSeq Acc Id: XP_038300007   ⟸   XM_038444079
- UniProtKB: A0A8I3P2A0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038438112   ⟸   XM_038582184
- UniProtKB: A0A8I3P2A0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845022028   ⟸   ENSCAFT00845027988


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000044575 UniProtKB/TrEMBL
  ENSCAFG00030025924 UniProtKB/TrEMBL
  ENSCAFG00845015696 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000063924.2 UniProtKB/TrEMBL
  ENSCAFT00030047887.1 UniProtKB/TrEMBL
  ENSCAFT00845027988 ENTREZGENE
  ENSCAFT00845027988.1 UniProtKB/TrEMBL
NCBI Gene DSPP ENTREZGENE
PANTHER DENTIN SIALOPHOSPHOPROTEIN UniProtKB/TrEMBL
  DENTIN SIALOPHOSPHOPROTEIN UniProtKB/TrEMBL
UniProt A0A8C0PYM2_CANLF UniProtKB/TrEMBL
  A0A8I3P2A0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0T5Z9_CANLF UniProtKB/TrEMBL