MTARC1 (mitochondrial amidoxime reducing component 1) - Rat Genome Database

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Gene: MTARC1 (mitochondrial amidoxime reducing component 1) Canis lupus familiaris
Analyze
Symbol: MTARC1
Name: mitochondrial amidoxime reducing component 1
RGD ID: 12346334
Description: ENCODES a protein that exhibits nitrite reductase (NO-forming) activity (ortholog); nitrite reductase activity (ortholog); oxidoreductase activity, acting on other nitrogenous compounds as donors (ortholog); INVOLVED IN cellular detoxification of nitrogen compound (ortholog); nitric oxide biosynthetic process (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); gastrointestinal stromal tumor (ortholog); Loeys-Dietz syndrome 4 (ortholog); FOUND IN nitric-oxide synthase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MARC1; mitochondrial amidoxime-reducing component 1; MOCO sulphurase C-terminal domain containing 1; MOSC1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13815,460,548 - 15,490,941 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3815,463,548 - 15,532,241 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3815,501,865 - 15,532,434 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03815,496,387 - 15,527,068 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3815,451,494 - 15,522,862 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13815,503,851 - 15,534,357 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03815,858,250 - 15,883,444 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03816,151,276 - 16,181,816 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MTARC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13815,460,548 - 15,490,941 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3815,463,548 - 15,532,241 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3815,501,865 - 15,532,434 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03815,496,387 - 15,527,068 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3815,451,494 - 15,522,862 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13815,503,851 - 15,534,357 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03815,858,250 - 15,883,444 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03816,151,276 - 16,181,816 (+)NCBIUU_Cfam_GSD_1.0
MTARC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381220,786,913 - 220,819,659 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1220,786,352 - 220,819,659 (+)EnsemblGRCh38hg38GRCh38
GRCh371220,960,255 - 220,993,001 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361219,026,894 - 219,054,353 (+)NCBINCBI36Build 36hg18NCBI36
Celera1194,179,397 - 194,207,116 (+)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1191,634,656 - 191,662,358 (+)NCBIHuRef
CHM1_11222,232,498 - 222,260,205 (+)NCBICHM1_1
T2T-CHM13v2.01220,026,620 - 220,059,373 (+)NCBIT2T-CHM13v2.0
Mtarc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391184,518,964 - 184,543,622 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1184,518,964 - 184,543,394 (-)EnsemblGRCm39 Ensembl
GRCm381184,786,767 - 184,811,743 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1184,786,767 - 184,811,313 (-)EnsemblGRCm38mm10GRCm38
MGSCv371186,610,646 - 186,635,192 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361186,487,555 - 186,512,101 (-)NCBIMGSCv36mm8
Celera1191,748,956 - 191,773,778 (-)NCBICelera
Cytogenetic Map1H5NCBI
cM Map189.07NCBI
Mtarc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81398,854,235 - 98,894,208 (-)NCBIGRCr8
mRatBN7.21396,324,377 - 96,362,677 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1396,339,757 - 96,397,796 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1398,845,403 - 98,868,427 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013100,244,818 - 100,267,603 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01397,427,640 - 97,450,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013102,693,679 - 102,724,120 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13102,698,546 - 102,721,218 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013107,375,873 - 107,398,500 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413100,747,272 - 100,806,258 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1395,859,205 - 95,880,141 (-)NCBICelera
Cytogenetic Map13q26NCBI
MTARC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2128,585,807 - 28,613,469 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1128,547,598 - 28,575,285 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01196,373,028 - 196,405,115 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11201,407,483 - 201,435,186 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1201,407,390 - 201,435,186 (+)Ensemblpanpan1.1panPan2
Mtarc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934456,229,847 - 56,255,778 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366501,478,037 - 1,504,611 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366501,477,138 - 1,504,501 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTARC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1010,190,835 - 10,216,175 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11010,190,759 - 10,264,467 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21012,257,867 - 12,288,355 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTARC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1258,654,316 - 8,744,579 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl258,717,436 - 8,743,652 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660559,000,217 - 9,029,492 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mtarc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248354,164,672 - 4,177,365 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248354,164,755 - 4,177,931 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MTARC1
503 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 12 6 6 1 7 7 6
Low 5 1 10 6 5 6 5 3 3
Below cutoff 5

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005640829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038464017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038464018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038464019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000018014   ⟹   ENSCAFP00000016681
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3815,463,548 - 15,485,413 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000061747   ⟹   ENSCAFP00000047414
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3815,463,548 - 15,532,241 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000077764   ⟹   ENSCAFP00000057233
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3815,463,548 - 15,486,446 (+)Ensembl
RefSeq Acc Id: XM_038448480   ⟹   XP_038304408
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03815,496,387 - 15,521,614 (+)NCBI
RefSeq Acc Id: XM_038448481   ⟹   XP_038304409
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03815,496,387 - 15,527,068 (+)NCBI
RefSeq Acc Id: XM_038464017   ⟹   XP_038319945
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3815,501,865 - 15,526,978 (+)NCBI
RefSeq Acc Id: XM_038464018   ⟹   XP_038319946
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3815,501,865 - 15,521,468 (+)NCBI
RefSeq Acc Id: XM_038464019   ⟹   XP_038319947
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3815,501,865 - 15,532,434 (+)NCBI
RefSeq Acc Id: XM_038522384   ⟹   XP_038378312
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13815,503,851 - 15,528,931 (+)NCBI
RefSeq Acc Id: XM_038522385   ⟹   XP_038378313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13815,503,851 - 15,534,357 (+)NCBI
RefSeq Acc Id: XM_038586186   ⟹   XP_038442114
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03816,151,276 - 16,176,361 (+)NCBI
RefSeq Acc Id: XM_038586187   ⟹   XP_038442115
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03816,151,276 - 16,181,816 (+)NCBI
RefSeq Acc Id: XM_038650593   ⟹   XP_038506521
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03815,858,250 - 15,883,444 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000057233   ⟸   ENSCAFT00000077764
RefSeq Acc Id: ENSCAFP00000016681   ⟸   ENSCAFT00000018014
RefSeq Acc Id: ENSCAFP00000047414   ⟸   ENSCAFT00000061747
RefSeq Acc Id: XP_038378313   ⟸   XM_038522385
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038378312   ⟸   XM_038522384
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038506521   ⟸   XM_038650593
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038304409   ⟸   XM_038448481
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SSQ1 (UniProtKB/TrEMBL),   A0A8I3S7H5 (UniProtKB/TrEMBL),   A0A8C0JM24 (UniProtKB/TrEMBL),   A0A8C0SR85 (UniProtKB/TrEMBL),   A0A8I3QDM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038304408   ⟸   XM_038448480
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RQK0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319947   ⟸   XM_038464019
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SSQ1 (UniProtKB/TrEMBL),   A0A8I3S7H5 (UniProtKB/TrEMBL),   A0A8C0JM24 (UniProtKB/TrEMBL),   A0A8C0SR85 (UniProtKB/TrEMBL),   A0A8I3QDM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319945   ⟸   XM_038464017
- Peptide Label: isoform X1
- UniProtKB: A0A8P0ND86 (UniProtKB/TrEMBL),   A0A8C0RQK0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319946   ⟸   XM_038464018
- Peptide Label: isoform X1
- UniProtKB: A0A8P0ND86 (UniProtKB/TrEMBL),   A0A8C0RQK0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442115   ⟸   XM_038586187
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JM24 (UniProtKB/TrEMBL),   A0A8C0SR85 (UniProtKB/TrEMBL),   A0A8C0SSQ1 (UniProtKB/TrEMBL),   A0A8I3QDM5 (UniProtKB/TrEMBL),   A0A8I3S7H5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442114   ⟸   XM_038586186
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RQK0 (UniProtKB/TrEMBL)
Protein Domains
MOSC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011336 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030021722 UniProtKB/TrEMBL
  ENSCAFG00040015900 UniProtKB/TrEMBL
  ENSCAFG00845030177 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000018014.5 UniProtKB/TrEMBL
  ENSCAFT00000077764.2 UniProtKB/TrEMBL
  ENSCAFT00000104376.1 UniProtKB/TrEMBL
  ENSCAFT00030039898.1 UniProtKB/TrEMBL
  ENSCAFT00040029258.1 UniProtKB/TrEMBL
  ENSCAFT00040029280.1 UniProtKB/TrEMBL
  ENSCAFT00040029491.1 UniProtKB/TrEMBL
  ENSCAFT00845053522.1 UniProtKB/TrEMBL
  ENSCAFT00845053573 ENTREZGENE
  ENSCAFT00845053573.1 UniProtKB/TrEMBL
InterPro MoCF_Sase_C UniProtKB/TrEMBL
  MOSC_N UniProtKB/TrEMBL
  Pyrv_Knase-like_insert_dom_sf UniProtKB/TrEMBL
NCBI Gene MARC1 ENTREZGENE
PANTHER MITOCHONDRIAL AMIDOXIME-REDUCING COMPONENT 1 UniProtKB/TrEMBL
  MOLYBDOPTERIN COFACTOR SULFURASE MOSC UniProtKB/TrEMBL
Pfam MOSC UniProtKB/TrEMBL
  MOSC_N UniProtKB/TrEMBL
PROSITE MOSC UniProtKB/TrEMBL
Superfamily-SCOP MOSC N-terminal domain-like UniProtKB/TrEMBL
  SSF50800 UniProtKB/TrEMBL
UniProt A0A8C0JM24 ENTREZGENE
  A0A8C0RQK0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SR85 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SSQ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QDM5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S7H5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0ND86 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43013 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-10-01 MTARC1  mitochondrial amidoxime reducing component 1  MARC1  mitochondrial amidoxime reducing component 1  Symbol and/or name change 5135510 APPROVED