NPY2R (neuropeptide Y receptor Y2) - Rat Genome Database

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Gene: NPY2R (neuropeptide Y receptor Y2) Canis lupus familiaris
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Symbol: NPY2R
Name: neuropeptide Y receptor Y2
RGD ID: 12330671
Description: ENCODES a protein that exhibits neuropeptide Y receptor activity (ortholog); peptide YY receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); behavioral fear response (ortholog); G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH alcohol use disorder (ortholog); atherosclerosis (ortholog); childhood absence epilepsy (ortholog); FOUND IN cilium (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neuropeptide Y receptor type 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11552,790,136 - 52,797,785 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1552,794,671 - 52,795,818 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1553,131,265 - 53,141,184 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01553,475,002 - 53,484,515 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1553,481,383 - 53,484,128 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11552,727,621 - 52,737,421 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01552,836,294 - 52,846,610 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01553,149,800 - 53,159,345 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:15670655   PMID:22301074  


Genomics

Comparative Map Data
NPY2R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11552,790,136 - 52,797,785 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1552,794,671 - 52,795,818 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1553,131,265 - 53,141,184 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01553,475,002 - 53,484,515 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1553,481,383 - 53,484,128 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11552,727,621 - 52,737,421 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01552,836,294 - 52,846,610 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01553,149,800 - 53,159,345 (+)NCBIUU_Cfam_GSD_1.0
NPY2R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384155,173,723 - 155,217,076 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4155,208,636 - 155,217,078 (+)EnsemblGRCh38hg38GRCh38
GRCh374156,094,875 - 156,138,228 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364156,349,232 - 156,357,678 (+)NCBINCBI36Build 36hg18NCBI36
Build 344156,487,385 - 156,495,832NCBI
Celera4153,460,186 - 153,468,632 (+)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4151,868,438 - 151,876,885 (+)NCBIHuRef
CHM1_14156,107,896 - 156,116,343 (+)NCBICHM1_1
T2T-CHM13v2.04158,505,608 - 158,548,978 (+)NCBIT2T-CHM13v2.0
Npy2r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39382,445,688 - 82,455,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl382,445,690 - 82,455,391 (-)EnsemblGRCm39 Ensembl
GRCm38382,538,383 - 82,548,989 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl382,538,383 - 82,548,084 (-)EnsemblGRCm38mm10GRCm38
MGSCv37382,342,305 - 82,352,007 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36382,624,310 - 82,634,013 (-)NCBIMGSCv36mm8
Celera382,557,426 - 82,567,083 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map336.49NCBI
Npy2r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82170,200,027 - 170,210,286 (-)NCBIGRCr8
mRatBN7.22167,901,999 - 167,912,165 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2167,903,879 - 167,905,024 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2175,099,298 - 175,100,444 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02173,120,230 - 173,121,376 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02167,713,107 - 167,714,253 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02181,528,949 - 181,538,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2181,530,832 - 181,531,978 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02200,942,882 - 200,952,072 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42150,554,962 - 150,556,108 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12174,209,622 - 174,210,769 (-)NCBI
Celera2161,929,373 - 161,930,519 (-)NCBICelera
Cytogenetic Map2q34NCBI
Npy2r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547111,796,278 - 11,804,114 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547111,796,278 - 11,804,114 (-)NCBIChiLan1.0ChiLan1.0
NPY2R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23153,087,172 - 153,132,447 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14153,442,534 - 153,487,785 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04147,542,551 - 147,586,397 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14159,360,854 - 159,404,224 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4159,401,080 - 159,402,231 (+)Ensemblpanpan1.1panPan2
Npy2r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530137,606,621 - 37,615,131 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365761,932,870 - 1,938,703 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365761,932,526 - 1,939,560 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPY2R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl874,039,616 - 74,047,817 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1874,039,959 - 74,048,398 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2878,331,707 - 78,340,148 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NPY2R
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17101,696,081 - 101,773,782 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7101,770,551 - 101,771,696 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603781,413,529 - 81,421,886 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Npy2r
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248483,048,413 - 3,054,495 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248483,049,009 - 3,054,548 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NPY2R
112 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 6
Low 3 7 5 4 5 3 6 8 1
Below cutoff 2 5 15 1 2 1 3 6 5 9

Sequence


RefSeq Acc Id: ENSCAFT00000013442   ⟹   ENSCAFP00000066087
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1552,794,671 - 52,795,818 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017841   ⟹   ENSCAFP00845013896
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1553,481,383 - 53,484,128 (+)Ensembl
RefSeq Acc Id: XM_005629373   ⟹   XP_005629430
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11552,790,136 - 52,797,785 (+)NCBI
Dog10K_Boxer_Tasha1553,133,499 - 53,141,184 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038451982   ⟹   XP_038307910
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1553,131,265 - 53,141,184 (+)NCBI
RefSeq Acc Id: XM_038496692   ⟹   XP_038352620
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11552,729,742 - 52,737,421 (+)NCBI
RefSeq Acc Id: XM_038496693   ⟹   XP_038352621
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11552,727,621 - 52,737,421 (+)NCBI
RefSeq Acc Id: XM_038559085   ⟹   XP_038415013
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01553,151,652 - 53,159,345 (+)NCBI
RefSeq Acc Id: XM_038559086   ⟹   XP_038415014
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01553,149,800 - 53,159,345 (+)NCBI
RefSeq Acc Id: XM_038623022   ⟹   XP_038478950
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01552,838,909 - 52,846,610 (+)NCBI
RefSeq Acc Id: XM_038623023   ⟹   XP_038478951
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01552,836,294 - 52,846,610 (+)NCBI
RefSeq Acc Id: XM_038688695   ⟹   XP_038544623
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01553,476,814 - 53,484,515 (+)NCBI
RefSeq Acc Id: XM_038688696   ⟹   XP_038544624
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01553,475,002 - 53,484,515 (+)NCBI
RefSeq Acc Id: XP_005629430   ⟸   XM_005629373
- Sequence:
RefSeq Acc Id: ENSCAFP00000066087   ⟸   ENSCAFT00000013442
RefSeq Acc Id: XP_038352621   ⟸   XM_038496693
RefSeq Acc Id: XP_038352620   ⟸   XM_038496692
RefSeq Acc Id: XP_038478951   ⟸   XM_038623023
RefSeq Acc Id: XP_038478950   ⟸   XM_038623022
RefSeq Acc Id: XP_038544624   ⟸   XM_038688696
RefSeq Acc Id: XP_038544623   ⟸   XM_038688695
RefSeq Acc Id: XP_038307910   ⟸   XM_038451982
RefSeq Acc Id: XP_038415014   ⟸   XM_038559086
RefSeq Acc Id: XP_038415013   ⟸   XM_038559085
RefSeq Acc Id: ENSCAFP00845013896   ⟸   ENSCAFT00845017841

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008476 Ensembl
  ENSCAFG00000050243 UniProtKB/TrEMBL
  ENSCAFG00030008386 UniProtKB/TrEMBL
  ENSCAFG00040013095 UniProtKB/TrEMBL
  ENSCAFG00845010147 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000101430.1 UniProtKB/TrEMBL
  ENSCAFT00030015385.1 UniProtKB/TrEMBL
  ENSCAFT00040024187.1 UniProtKB/TrEMBL
  ENSCAFT00845017841.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  NPY2_rcpt UniProtKB/TrEMBL
NCBI Gene NPY2R ENTREZGENE
PANTHER NEUROPEPTIDE Y RECEPTOR UniProtKB/TrEMBL
  NEUROPEPTIDE Y RECEPTOR TYPE 2 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  NRPEPTIDEY2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0SG18_CANLF UniProtKB/TrEMBL
  A0A8I3RVM8_CANLF UniProtKB/TrEMBL