TAX1BP3 (Tax1 binding protein 3) - Rat Genome Database

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Gene: TAX1BP3 (Tax1 binding protein 3) Canis lupus familiaris
Analyze
Symbol: TAX1BP3
Name: Tax1 binding protein 3
RGD ID: 12328065
Description: ENCODES a protein that exhibits beta-catenin binding (inferred); INVOLVED IN negative regulation of cell population proliferation (ortholog); ASSOCIATED WITH Abderhalden-Kaufmann-Lignac Syndrome (ortholog); arrhythmogenic right ventricular cardiomyopathy (ortholog); Canavan disease (ortholog); FOUND IN actin cytoskeleton (inferred); basolateral plasma membrane (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Tax1 (human T-cell leukemia virus type I) binding protein 3; tax1-binding protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1947,492,371 - 47,497,298 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl947,493,069 - 47,497,203 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha946,654,625 - 46,659,564 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0948,337,717 - 48,342,666 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl948,337,720 - 48,342,619 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1947,115,492 - 47,120,433 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0947,404,610 - 47,409,549 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0947,460,236 - 47,465,179 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TAX1BP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1947,492,371 - 47,497,298 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl947,493,069 - 47,497,203 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha946,654,625 - 46,659,564 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0948,337,717 - 48,342,666 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl948,337,720 - 48,342,619 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1947,115,492 - 47,120,433 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0947,404,610 - 47,409,549 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0947,460,236 - 47,465,179 (-)NCBIUU_Cfam_GSD_1.0
TAX1BP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38173,662,895 - 3,668,578 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl173,662,895 - 3,668,679 (-)EnsemblGRCh38hg38GRCh38
GRCh37173,566,189 - 3,571,872 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36173,512,938 - 3,518,722 (-)NCBINCBI36Build 36hg18NCBI36
Build 34173,512,938 - 3,518,722NCBI
Celera173,579,928 - 3,585,715 (-)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef173,457,894 - 3,463,683 (-)NCBIHuRef
CHM1_1173,576,823 - 3,582,609 (-)NCBICHM1_1
T2T-CHM13v2.0173,551,947 - 3,557,633 (-)NCBIT2T-CHM13v2.0
Tax1bp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391173,067,909 - 73,072,872 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1173,067,909 - 73,073,988 (+)EnsemblGRCm39 Ensembl
GRCm381173,177,083 - 73,182,046 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1173,177,083 - 73,183,162 (+)EnsemblGRCm38mm10GRCm38
MGSCv371172,990,585 - 72,995,548 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361172,993,278 - 72,998,241 (+)NCBIMGSCv36mm8
Celera1180,714,177 - 80,719,138 (+)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.25NCBI
Tax1bp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81058,294,357 - 58,298,875 (+)NCBIGRCr8
mRatBN7.21057,795,845 - 57,800,363 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1057,795,382 - 57,800,363 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1062,451,524 - 62,456,041 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01061,939,983 - 61,944,500 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01057,439,136 - 57,443,653 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01059,743,356 - 59,748,063 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1059,743,544 - 59,748,062 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01059,482,530 - 59,487,239 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41060,054,096 - 60,058,595 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11060,067,718 - 60,072,217 (+)NCBI
Celera1056,918,760 - 56,923,259 (+)NCBICelera
Cytogenetic Map10q24NCBI
Tax1bp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546713,146,527 - 13,151,109 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546713,146,527 - 13,151,109 (+)NCBIChiLan1.0ChiLan1.0
TAX1BP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21911,274,594 - 11,280,369 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11713,240,101 - 13,245,815 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0173,713,211 - 3,718,959 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1173,709,600 - 3,715,342 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl173,709,600 - 3,715,342 (-)Ensemblpanpan1.1panPan2
Tax1bp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560255,533,701 - 55,539,675 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936677361,300 - 367,234 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAX1BP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1249,754,166 - 49,759,412 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11249,754,162 - 49,759,026 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21251,614,252 - 51,619,116 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TAX1BP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,166,151 - 3,171,292 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605918,658,710 - 18,663,867 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tax1bp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247866,318,879 - 6,323,816 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247866,318,879 - 6,323,835 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TAX1BP3
42 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000030748   ⟹   ENSCAFP00000028582
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl947,493,069 - 47,497,196 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000089976   ⟹   ENSCAFP00000065260
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl947,493,214 - 47,497,203 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845029181   ⟹   ENSCAFP00845022948
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl948,337,720 - 48,342,619 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845029198   ⟹   ENSCAFP00845022964
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl948,338,560 - 48,342,619 (-)Ensembl
RefSeq Acc Id: XM_003639265   ⟹   XP_003639313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1947,492,371 - 47,497,298 (-)NCBI
Dog10K_Boxer_Tasha946,654,625 - 46,659,564 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038486695   ⟹   XP_038342623
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1947,115,492 - 47,120,433 (-)NCBI
RefSeq Acc Id: XM_038548562   ⟹   XP_038404490
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0947,460,236 - 47,465,179 (-)NCBI
RefSeq Acc Id: XM_038612503   ⟹   XP_038468431
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0947,404,610 - 47,409,549 (-)NCBI
RefSeq Acc Id: XM_038677779   ⟹   XP_038533707
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0948,337,717 - 48,342,666 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003639313   ⟸   XM_003639265
- UniProtKB: A0A8C0MWY5 (UniProtKB/TrEMBL),   A0A8C0K555 (UniProtKB/TrEMBL),   A0A8I3NPF4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000028582   ⟸   ENSCAFT00000030748
RefSeq Acc Id: ENSCAFP00000065260   ⟸   ENSCAFT00000089976
RefSeq Acc Id: XP_038342623   ⟸   XM_038486695
RefSeq Acc Id: XP_038468431   ⟸   XM_038612503
RefSeq Acc Id: XP_038533707   ⟸   XM_038677779
- UniProtKB: A0A8C0MWY5 (UniProtKB/TrEMBL),   A0A8C0K555 (UniProtKB/TrEMBL),   A0A8I3NPF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404490   ⟸   XM_038548562
- UniProtKB: A0A8C0K555 (UniProtKB/TrEMBL),   A0A8C0MWY5 (UniProtKB/TrEMBL),   A0A8I3NPF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845022964   ⟸   ENSCAFT00845029198
RefSeq Acc Id: ENSCAFP00845022948   ⟸   ENSCAFT00845029181
Protein Domains
PDZ

Promoters
RGD ID:13684727
Promoter ID:EPDNEW_C2796
Type:initiation region
Name:TAX1BP3_1
Description:Tax1 binding protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1947,497,219 - 47,497,279EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019347 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030009864 UniProtKB/TrEMBL
  ENSCAFG00040006050 UniProtKB/TrEMBL
  ENSCAFG00845016451 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000030748.5 UniProtKB/TrEMBL
  ENSCAFT00000089976.2 UniProtKB/TrEMBL
  ENSCAFT00030018242.1 UniProtKB/TrEMBL
  ENSCAFT00030018288.1 UniProtKB/TrEMBL
  ENSCAFT00040011299.1 UniProtKB/TrEMBL
  ENSCAFT00040011310.1 UniProtKB/TrEMBL
  ENSCAFT00845029181 ENTREZGENE
  ENSCAFT00845029181.1 UniProtKB/TrEMBL
  ENSCAFT00845029198.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
InterPro PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  Tax1-binding_p3 UniProtKB/TrEMBL
KEGG Report cfa:100856105 UniProtKB/TrEMBL
NCBI Gene TAX1BP3 ENTREZGENE
PANTHER DISCS LARGE UniProtKB/TrEMBL
  DISKS LARGE 1 TUMOR SUPPRESSOR PROTEIN UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
PIRSF Tax1-binding_p3 UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/TrEMBL
UniProt A0A8C0K555 ENTREZGENE
  A0A8C0MWY5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QD58_CANLF UniProtKB/TrEMBL
  A0A8I3NPF4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NZV9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:47126 ENTREZGENE